scholarly journals Newer Treatment Modalities in Urticaria

2021 ◽  
pp. 472-476
Author(s):  
Meghana Pendam ◽  
Bhushan Madke
Keyword(s):  
Health Care Expenditures ◽  
Treatment Modalities ◽  
Autologous Serum ◽  
Clinical Disorder ◽  
First Line Therapy ◽  
Quality Life ◽  
Negative Effect ◽  
Quality Of Living ◽  
Inflammatory Drugs

Wheals (hives), angioedema, or both are symptoms of urticaria, a chronic clinical disorder. Urticaria has a complicated pathogenesis, as well as a large disease burden, a negative effect on health-care expenditures and quality of living. Urticaria could also be a chronic condition that affects up to 1% of the general population at some stage in their lives and can drastically impair quality life. The use of second-generation, non-sedating antihistamines has replaced antihistamines to use as the first-line therapy. However, urticaria can be difficult to manage in some cases; in these cases, alternate treatment approaches must be considered. This article reviews antihistamines, leukotriene antagonists, anti-inflammatory drugs, biologicals, subcutaneous autologous serum therapy, doxepin, cyclosporine ,tranexamic acid and other newer treatment modalities.

scholarly journals Management of Early Osteoarthritis

2020 ◽  
Author(s):  
Ahmed Mostafa Kotb Aziz
Keyword(s):  
Cost Effective ◽  
Cyst Formation ◽  
Degenerative Joint Disease ◽  
Joint Arthroplasty ◽  
Joint Disease ◽  
Treatment Modalities ◽  
Cost Effective Treatment ◽  
Inflammatory Drugs ◽  
Lifestyle Physical Activity

Osteoarthritis (OA) is a chronic degenerative joint disease of dynamic pathology with multiple etiologies. It involves progressive process of softening, loss of articular cartilage, subchondral bone sclerosis, development of osteophytes, and cyst formation. OA usually contributes to decreased activity associated with aging, secondary to diminished function and pain, thus consequently impairing quality of life. It is well established that pain due to OA, swelling, or stiffness can make it difficult for individuals to perform simple daily living activities. Although OA is not curable, a variety of treatment modalities are available to improve symptoms. Main elements include pain management maneuvers, education, changing lifestyle physical activity (PA), and weight reduction in case of overweight. Although total joint arthroplasty (TJA) is considered a cost-effective treatment for people with OA, TJA should only be considered after failure of conservative treatments. Symptoms of OA are usually managed by either pharmachological or nonpharmachological protocols; joint replacement surgeries are considered in advanced cases. Analgesics remain the keystone of pharmacological treatment for OA symptoms, including paracetamol, topical and oral nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids. However, benefits from paracetamol and opioids are minimal, and NSAIDs are not ideal for many patients because they have many side-effects. Intra-articular therapies such as corticosteroids are also commonly used, though usually with short-term benefits.

scholarly journals Role of Agnikarma in Pain Management of Various Musculoskeletal Disorders: A Review Study

2021 ◽  
pp. 89-96
Author(s):  
Badwe Yogesh ◽  
Shilvant Rishabh ◽  
Shinde Jyoti
Keyword(s):  
Pain Management ◽  
Musculoskeletal Disorders ◽  
Pain Treatment ◽  
Cost Effective ◽  
Modern Medicine ◽  
Treatment Modalities ◽  
Research Article ◽  
Inflammatory Drugs

Agnikarma is one of the important Para-surgical procedures described in Ayurveda, which has been widely used in the clinical practice now days. Sushruta has given detail description about Agnikarma. Superiority of Agnikarma over other the treatment modalities are timely described by our ancienter because of its Apunrabhavatva i.e., no recurrence property. Pain (Ruja) is the cardinal feature of most of the musculoskeletal disorders and it can affect the quality of life. In modern lifestyle, patient needs instant relief from pain. Treatment available in modern medicine commonly NSAID’s (Nonsteroidal anti-inflammatory drugs) but it has some hazardous effects on body. This review is an attempt has been made to study various research article, analyzed the role of Agnikarma and its applicability on various painful disorders which help to gain best knowledge about Agnikarma. In this article total 15 research works from various journals have been studied conducted on Agnikarma. Agnikarma was found very important tool in pain management of many musculoskeletal disorders. It was found safe, easy, cost-effective and OPD level procedure.  

scholarly journals Safe therapy of osteoarthritis: place of topical nonsteroidal anti-inflammatory drugs

2020 ◽  
pp. 128-134
Author(s):  
N. V. Chichasova ◽  
G. R. Imametdinova ◽  
A. M. Lila
Keyword(s):  
Negative Impact ◽  
Social Significance ◽  
The Social ◽  
Negative Effect ◽  
Inflammatory Drugs ◽  
Transdermal Penetration ◽  
Anti Inflammatory ◽  
Social Importance ◽  
Transdermal Transport

The article discusses the social significance of osteoarthritis as a widespread disease that develops mainly in older people, which makes it difficult to carry out anti-inflammatory and analgesic therapy due to the frequent combination of osteoarthritis with other diseases at this age, the need to treat comorbid conditions, which is often poorly combined with systemic therapy with non-steroidal anti-inflammatory drugs. It is noted that osteoarthritis not only worsens the quality of life of patients, but also leads to a decrease in the length of their life, which emphasizes the medical and social importance of conducting the safest possible therapy for this disease. Data on the negative impact of the presence of chronic pain on the progression of osteoarthritis are presented. The negative aspects of the use of oral forms of non-steroidal anti-inflammatory drugs are discussed: the development of adverse events primarily from the gastrointestinal tract and cardiovascular system, the negative effect on the synthesis of glycoaminoglycans («chondronegative effect»). Discusses the place of topical forms of NSAIDs in the treatment of patients with osteoarthritis in accordance with the recommendations of the International society for the use of topical forms of NSAIDs in the management of patients with osteoarthritis of large and small joints. Data on transdermal transport of the topical form of diclofenac, a small molecule with lipophilic properties, are presented. Data on the effectiveness of topical forms of diclofenac in comparison with oral forms are presented according to numerous randomized controlled trials, and the comparable effectiveness of both forms of diclofenac is demonstrated, with maximum safety of the topical form. A special structure of Voltaren® Emulgel (Voltaren® Emulgel), combining the properties of a gel and cream, which provides rapid transdermal penetration and longer retention of the active substance in the area of inflammation, is described, as well as a special prolonged form of Voltaren® Emulgel), which creates additional convenience for use.

Measuring Liveability by Exploring Urban Qualities of Kissy Street, Freetown, Sierra Leone

2016 ◽  
Vol 41 (2) ◽  
pp. 23-30 ◽  
Author(s):  
Fodei M. Conteh ◽  
Derya Oktay
Keyword(s):  
Inner City ◽  
Public Space ◽  
Sierra Leone ◽  
Mixed Method ◽  
Structured Interviews ◽  
Human Comfort ◽  
Street Space ◽  
Negative Effect ◽  
Quality Of Living

With increasing urbanisation in developing countries and the concomitant overcrowding on streets, serious questions remain about the liveability of inner-city residential-commercial streets. This paper contends that lively streets are not necessarily liveable streets. Liveability is defined by other criteria that take cognizance of human comfort and capabilities within living environments. Observations suggest an uneasy relationship between a crowded public space and the private residential spaces that sit next to them. The paper’s focus is to measure the liveability of a lively but overcrowded street and how its everyday use affects the physical characteristics of buildings, the activities, and the wellbeing of residents. Employing a mixed-method strategy, the study draws on observations, semi-structured interviews, and questionnaire survey of residents, shopkeepers, and street traders. The findings suggest that an overcrowded street space has a negative effect on the liveability and quality of living of residents and other users but that this is tempered by intra-dependency amongst the users and the negotiation of the rights accruing to all as individuals and as groups.

Vocation Education Quality from Demand Side’s Perspective: The Case of Transport Technology Universities in the North of Vietnam

2019 ◽  
Vol 10 (11) ◽  
pp. 1089-1097
Author(s):  
Nguyen Quynh Hoa ◽  
◽  
Phung Chu Hoang ◽  
Keyword(s):  
Vocational Training ◽  
Vocational Education And Training ◽  
Quality Outcomes ◽  
The North ◽  
Job Opportunities ◽  
Management Capacity ◽  
Negative Effect ◽  
Training Quality ◽  
And Training

Quality outcomes from vocational education and training (VET) are fundamental to ensuring a skilled workforce and supporting a productive economy. The quality of vocational training from the demand’s perspective is defined as meeting the customer specification, needs or requirements. Using the method of Exploratory Factor Analysis (EFA) and Multiple Regression Analysis to get the analytical results of 275 respondents as graduates of University of Transport and Communication, University of Transport Technology (the two universities training on transportation in the North of Vietnam), the results show that factors are measured by the observed variables in the study that ensure reliability and relevance. The descriptive statistics result of vocational training quality is 3.28, while all independent variables are at average level (between 3.1 to 3.48) with the highest value related to the quality of the teacher and the lowest are facilities and training programs and management capacity of university. However, the regression results show that the qualification of the teacher, material facilities and training program, management capacity and job opportunities at the training school do not affect the quality of the training while “Learners-NH” have a great positive effect and the labor market information has a negative effect on the training quality of the school significantly. Base on those data, some policy recommendations have been given out in order to improve the training quality of transport technology universities in the north of Vietnam in particular and the vocational training quality of Vietnam in general.

The Impact of Competitive Quasi-Market on Service Delivery in Benue State University, Makurdi Nigeria

GIS Business ◽  
2019 ◽  
Vol 14 (4) ◽  
pp. 85-98
Author(s):  
Idoko Peter
Keyword(s):  
Service Delivery ◽  
A Priori ◽  
Least Square ◽  
Secondary Source ◽  
State University ◽  
Ordinary Least Square ◽  
Negative Effect ◽  
The Impact ◽  
The Relationship

This research the impact of competitive quasi market on service delivery in Benue State University, Makurdi Nigeria. Both primary and secondary source of data and information were used for the study and questionnaire was used to extract information from the purposively selected respondents. The population for this study is one hundred and seventy three (173) administrative staff of Benue State University selected at random. The statistical tools employed was the classical ordinary least square (OLS) and the probability value of the estimates was used to tests hypotheses of the study. The result of the study indicates that a positive relationship exist between Competitive quasi marketing in Benue State University, Makurdi Nigeria (CQM) and Transparency in the service delivery (TRSP) and the relationship is statistically significant (p<0.05). Competitive quasi marketing (CQM) has a negative effect on Observe Competence in Benue State University, Makurdi Nigeria (OBCP) and the relationship is not statistically significant (p>0.05). Competitive quasi marketing (CQM) has a positive effect on Innovation in Benue State University, Makurdi Nigeria (INVO) and the relationship is statistically significant (p<0.05) and in line with a priori expectation. This means that a unit increases in Competitive quasi marketing (CQM) will result to a corresponding increase in innovation in Benue State University, Makurdi Nigeria (INVO) by a margin of 22.5%. It was concluded that government monopoly in the provision of certain types of services has greatly affected the quality of service experience in the institution. It was recommended among others that the stakeholders in the market has to be transparent so that the system will be productive to serve the society effectively

INFLUENCE OF DICARBOXYLIC ACIDS ON SOWING QUALITY OF SPRING BARLEY

1970 ◽  
pp. 22-25
Author(s):  
N. N. Loy ◽  
S. N. Gulina
Keyword(s):  
Organic Acids ◽  
Spring Barley ◽  
Dose Range ◽  
Dicarboxylic Acids ◽  
Rotary Machine ◽  
Working Solution ◽  
Negative Effect ◽  
Sprouted Seeds

The effect of presowing seed treatment on various concentrations of dicarboxylic (organic) acids on the sowing characteristics of spring barley has been studied. Seeds were treated with organic acids obtained by exposing cuttings to the radiation with a dose of 100 kGy and consequent hydrolysis, in concentrations: 1•10-7 %; 1•10-9; 1•10-11; 1•10-13 and 1•10-15 % on a laboratory rotary machine RVO-64 for one day before laying for germination. Distilled water was used for the control case. The rate of application of the working solution calculated as 10 liters / ton of seeds. Seeds were germinated in filter paper rolls in accordance with GOST 12038-84 requirements. The temperature was maintained at +24 ° C in the thermostat where the glasses with rolls were placed. For determination of germinative power and laboratory germination the sprouted seeds were evaluated after three and seven days, respectively. In laboratory experiments it was established that the treatment of barley seeds of varieties Zazersky 85, Nur and Vladimir with organic acids (OK) in different concentrations had both a stimulating and a negative effect. On the Zazersky 85 variety, in variants with acid concentrations of 1•10-9 and 1•10-11, an increase in germination energy (EP) by 2-4% and a significant decrease (by 3-4%) of laboratory germination (LV) of barley seeds were noted. On the Nur variety, the increase in EP was observed at 4% (concentration 1•10-11), LV and seed growth force (CPC) by 2-7% at a concentration of 1•10-7 and in the dose range 1•10-11 - 1•10-14 compared to the control values. On the grade of Vladimir, an increase in EP, LV, and CPC was found to increase by 1-6% at concentrations OK 1•10-7 and 1•10-13. It was shown that the treatment of seeds with acids led to an increase in the length of the germ in all studied varieties (by 3-9%) and dry biomass of 7-day-old seedlings - by 3-6%. Consequently, the treatment of seeds with a mixture of dicarboxylic acids has a stimulating effect on the sowing quality of spring barley.

Beech sapling architecture following small and medium gap disturbances in silver fir-beech old-growth forests in Slovenia

2005 ◽  
Vol 156 (12) ◽  
pp. 481-486 ◽  
Author(s):  
Jurij Diaci ◽  
Lahorka Kozjek
Keyword(s):  
Light Intensity ◽  
Quality Characteristics ◽  
Stem Length ◽  
Silver Fir ◽  
Beech Forests ◽  
Vertical Growth ◽  
Relative Light Intensity ◽  
Stem Bending ◽  
Negative Effect

The objective of our research was to examine the effect of canopy shading on beech sapling architecture in the oldgrowth silver fir-beech forests of Pecka and Rajhenavski Rog. In August 2003 we sampled one plot (352 m2) in a large gap in Pecka, which was a result of a strong windstorm in 1983, and eight small gaps (26–78 m2) with similar sapling heights (3.8–8 m). A ground view of each gap was drawn including the characteristics of gap border trees and the density of separate sapling layers was recorded. The height and diameter were measured for each sapling, as well as the following quality characteristics on selected dominant saplings: width of the crown,number of larger branches and knots (&gt;1/3 DBH), intensity of stem bending, deviation from vertical growth, number of terminal shoots, and the type of damage. The results show a negative effect of high canopy shading (estimated relative light intensity was below 5%) on the architectural quality of saplings. A lower overall density of saplings, greater intensity of bending and deviation from vertical growth, a shorter stem length without branches, a larger number of saplings with two terminal shoots, and a larger number of damaged saplings were observed in small gaps.

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