scholarly journals REFLECTIONS FROM COASTAL STRUCTURES

1988 ◽  
Vol 1 (21) ◽  
pp. 58 ◽  
Author(s):  
N.W.H. Allsop ◽  
S.S.L. Hettiarachchi
Keyword(s):  
Wave Motion ◽  
Significant Contribution ◽  
Numerical Models ◽  
Coastal Structures ◽  
Wave Reflections ◽  
Reflected Waves ◽  
Sea Bed ◽  
Wide Range ◽  
Alternative Structure ◽  
General Reduction

Wave reflections at and within a coastal harbour may make a significant contribution to wave disturbance in the harbour. Reflected waves may lead to danger to vessels navigating close to structures, and may reduce the availability of berths within the harbour. Wave reflections may also increase local scour or general reduction in sea bed levels. In the design of breakwaters, sea walls, and coastal revetments, it is therefore important to estimate and compare the reflection performance of alternative structure types. In the use of numerical models of wave motion within harbours, it is essential to define realistically the reflection properties of each boundary. This paper presents results from a study of the reflection performance of a wide range of structures used in coastal and harbour engineering.

scholarly journals Two-Dimensional Numerical Modeling of Flow in Physical Models of Rock Vane and Bendway Weir Configurations

Water ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 458
Author(s):  
Drew C. Baird ◽  
Benjamin Abban ◽  
S. Michael Scurlock ◽  
Steven B. Abt ◽  
Christopher I. Thornton
Keyword(s):  
Numerical Modeling ◽  
Physical Model ◽  
Numerical Models ◽  
Hydraulic Performance ◽  
Physical Models ◽  
Protection Measures ◽  
Design Engineers ◽  
Model Study ◽  
Study Results ◽  
Wide Range

While there are a wide range of design recommendations for using rock vanes and bendway weirs as streambank protection measures, no comprehensive, standard approach is currently available for design engineers to evaluate their hydraulic performance before construction. This study investigates using 2D numerical modeling as an option for predicting the hydraulic performance of rock vane and bendway weir structure designs for streambank protection. We used the Sedimentation and River Hydraulics (SRH)-2D depth-averaged numerical model to simulate flows around rock vane and bendway weir installations that were previously examined as part of a physical model study and that had water surface elevation and velocity observations. Overall, SRH-2D predicted the same general flow patterns as the physical model, but over- and underpredicted the flow velocity in some areas. These over- and underpredictions could be primarily attributed to the assumption of negligible vertical velocities. Nonetheless, the point differences between the predicted and observed velocities generally ranged from 15 to 25%, with some exceptions. The results showed that 2D numerical models could provide adequate insight into the hydraulic performance of rock vanes and bendway weirs. Accordingly, design guidance and implications of the study results are presented for design engineers.

scholarly journals Breeding Strategies to Improve Miscanthus as a Sustainable Source of Biomass for Bioenergy and Biorenewable Products

Agronomy ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 673 ◽  
Author(s):  
John Clifton-Brown ◽  
Kai-Uwe Schwarz ◽  
Danny Awty-Carroll ◽  
Antonella Iurato ◽  
Heike Meyer ◽  
...  
Keyword(s):  
Significant Contribution ◽  
Perennial Grass ◽  
Time Frame ◽  
Eastern Asia ◽  
Germplasm Collections ◽  
Naturally Occurring ◽  
Wide Range ◽  
Yield Quality ◽  
Short Time ◽  
Commercial Expansion

Miscanthus, a C4 perennial grass native to Eastern Asia, is being bred to provide biomass for bioenergy and biorenewable products. Commercial expansion with the clonal hybrid M. × giganteus is limited by low multiplication rates, high establishment costs and drought sensitivity. These limitations can be overcome by breeding more resilient Miscanthus hybrids propagated by seed. Naturally occurring fast growing indigenous Miscanthus species are found in diverse environments across Eastern Asia. The natural diversity provides for plant breeders, the genetic resources to improve yield, quality, and resilience for a wide range of climates and adverse abiotic stresses. The challenge for Miscanthus breeding is to harness the diversity through selections of outstanding wild types, parents, and progenies over a short time frame to deploy hybrids that make a significant contribution to a world less dependent on fossil resources. Here are described the strategies taken by the Miscanthus breeding programme at Aberystwyth, UK and its partners. The programme built up one of the largest Miscanthus germplasm collections outside Asia. We describe the initial strategies to exploit the available genetic diversity to develop varieties. We illustrate the success of combining diverse Miscanthus germplasm and the selection criteria applied across different environments to identify promising hybrids and to develop these into commercial varieties. We discuss the potential for molecular selections to streamline the breeding process.

Dynamical Evolution of Globular Clusters with Mass Spectrum

1991 ◽  
Vol 9 (1) ◽  
pp. 41-44
Author(s):  
Hyung Mok Lee
Keyword(s):  
Mass Spectrum ◽  
Globular Clusters ◽  
Numerical Models ◽  
Relaxation Times ◽  
Dynamical Evolution ◽  
Planck Equation ◽  
Mass Function ◽  
Low Mass Stars ◽  
Wide Range ◽  
Three Body

AbstractWe present a series of numerical models describing the dynamical evolution of globular clusters with a mass spectrum, based on integration of the Fokker-Planck equation. We include three-body binary heating and a steady galactic tidal field. A wide range of initial mass functions is adopted and the evolution of the mass function is examined. The mass function begins to change appreciably during the post-collapse expansion phase due to the selective evaporation of low mass stars through the tidal boundary. One signature of highly evolved clusters is thus the significant flattening of the mass function. The age (in units of the half-mass relaxation time) increases very rapidly beyond about 100 signifying the final stage of cluster disruption. This appears to be consistent with the sharp cut-off of half-mass relaxation times at near 108 years for the Galactic globular clusters.

Coupled Thermo-Hydro-Geochemical Models of Engineered Barrier Systems: The Febex Project

2000 ◽  
Vol 663 ◽  
Author(s):  
J. Samper ◽  
R. Juncosa ◽  
V. Navarro ◽  
J. Delgado ◽  
L. Montenegro ◽  
...  
Keyword(s):  
Large Scale ◽  
Reference Model ◽  
Numerical Models ◽  
Full Scale ◽  
Small Scale ◽  
Model Parameters ◽  
In Situ Test ◽  
Wide Range ◽  
Engineered Barrier

ABSTRACTFEBEX (Full-scale Engineered Barrier EXperiment) is a demonstration and research project dealing with the bentonite engineered barrier designed for sealing and containment of waste in a high level radioactive waste repository (HLWR). It includes two main experiments: an situ full-scale test performed at Grimsel (GTS) and a mock-up test operating since February 1997 at CIEMAT facilities in Madrid (Spain) [1,2,3]. One of the objectives of FEBEX is the development and testing of conceptual and numerical models for the thermal, hydrodynamic, and geochemical (THG) processes expected to take place in engineered clay barriers. A significant improvement in coupled THG modeling of the clay barrier has been achieved both in terms of a better understanding of THG processes and more sophisticated THG computer codes. The ability of these models to reproduce the observed THG patterns in a wide range of THG conditions enhances the confidence in their prediction capabilities. Numerical THG models of heating and hydration experiments performed on small-scale lab cells provide excellent results for temperatures, water inflow and final water content in the cells [3]. Calculated concentrations at the end of the experiments reproduce most of the patterns of measured data. In general, the fit of concentrations of dissolved species is better than that of exchanged cations. These models were later used to simulate the evolution of the large-scale experiments (in situ and mock-up). Some thermo-hydrodynamic hypotheses and bentonite parameters were slightly revised during TH calibration of the mock-up test. The results of the reference model reproduce simultaneously the observed water inflows and bentonite temperatures and relative humidities. Although the model is highly sensitive to one-at-a-time variations in model parameters, the possibility of parameter combinations leading to similar fits cannot be precluded. The TH model of the “in situ” test is based on the same bentonite TH parameters and assumptions as for the “mock-up” test. Granite parameters were slightly modified during the calibration process in order to reproduce the observed thermal and hydrodynamic evolution. The reference model captures properly relative humidities and temperatures in the bentonite [3]. It also reproduces the observed spatial distribution of water pressures and temperatures in the granite. Once calibrated the TH aspects of the model, predictions of the THG evolution of both tests were performed. Data from the dismantling of the in situ test, which is planned for the summer of 2001, will provide a unique opportunity to test and validate current THG models of the EBS.

scholarly journals Development of Anti-Infectives Using Phage Display: Biological Agents against Bacteria, Viruses, and Parasites

2012 ◽  
Vol 56 (9) ◽  
pp. 4569-4582 ◽  
Author(s):  
Johnny X. Huang ◽  
Sharon L. Bishop-Hurley ◽  
Matthew A. Cooper
Keyword(s):  
Phage Display ◽  
Significant Contribution ◽  
Biological Agents ◽  
Preclinical Development ◽  
Phage Display Technology ◽  
Whole Cells ◽  
Drug Candidates ◽  
Phage Display Libraries ◽  
Wide Range ◽  
Display Technology

ABSTRACTThe vast majority of anti-infective therapeutics on the market or in development are small molecules; however, there is now a nascent pipeline of biological agents in development. Until recently, phage display technologies were used mainly to produce monoclonal antibodies (MAbs) targeted against cancer or inflammatory disease targets. Patent disputes impeded broad use of these methods and contributed to the dearth of candidates in the clinic during the 1990s. Today, however, phage display is recognized as a powerful tool for selecting novel peptides and antibodies that can bind to a wide range of antigens, ranging from whole cells to proteins and lipid targets. In this review, we highlight research that exploits phage display technology as a means of discovering novel therapeutics against infectious diseases, with a focus on antimicrobial peptides and antibodies in clinical or preclinical development. We discuss the different strategies and methods used to derive, select, and develop anti-infectives from phage display libraries and then highlight case studies of drug candidates in the process of development and commercialization. Advances in screening, manufacturing, and humanization technologies now mean that phage display can make a significant contribution in the fight against clinically important pathogens.

scholarly journals The role of Edge-Driven Convection in the generation of volcanism I: a 2D systematic study

2020 ◽  
Author(s):  
Antonio Manjón-Cabeza Córdoba ◽  
Maxim Ballmer
Keyword(s):  
Numerical Models ◽  
High Volume ◽  
Oceanic Lithosphere ◽  
Companion Paper ◽  
Small Scale ◽  
Continental Lithosphere ◽  
Transient Phenomenon ◽  
Mantle Viscosity ◽  
Wide Range

Abstract. The origin of intraplate volcanism is not explained by the plate tectonic theory, and several models have been put forward for explanation. One of these models involves Edge-Driven Convection (EDC), in which cold and thick continental lithosphere is juxtaposed to warm and thin oceanic lithosphere to trigger convective instability. To test whether EDC can produce long-lived high-volume magmatism, we run numerical models of EDC for a wide range of mantle properties and edge (i.e., the oceanic-continental transition) geometries. We find that the most important parameters that govern EDC are the rheological paramaters mantle viscosity η0 and activation energy Ea. However, even the maximum melting volumes found in our models are insufficient to account for island-building volcanism on old seafloor, such as at the Canary Islands and Cape Verde. Also, beneath old seafloor, localized EDC-related melting commonly transitions into widespread melting due to small-scale sublithospheric convection, inconsistent with the distribution of volcanism at these volcanic chains. In turn, EDC is a good candidate to sustain the formation of small seamounts on young seafloor, as it is a highly transient phenomenon that occurs in all our models soon after initiation. In a companion paper, we investigate the implications of interaction of EDC with mantle-plume activity.

scholarly journals The role of edge-driven convection in the generation of volcanism – Part 1: A 2D systematic study

Solid Earth ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 613-632
Author(s):  
Antonio Manjón-Cabeza Córdoba ◽  
Maxim D. Ballmer
Keyword(s):  
Numerical Models ◽  
High Volume ◽  
Oceanic Lithosphere ◽  
Companion Paper ◽  
Rheological Parameters ◽  
Small Scale ◽  
Transient Phenomenon ◽  
Mantle Viscosity ◽  
Wide Range

Abstract. The origin of intraplate volcanism is not explained by plate tectonic theory, and several models have been put forward for explanation. One of these models involves edge-driven convection (EDC), in which cold and thick continental lithosphere is juxtaposed with warm and thin oceanic lithosphere to trigger convective instability. To test whether EDC can produce long-lived high-volume magmatism, we run numerical models of EDC for a wide range of mantle properties and edge (i.e., the oceanic–continental transition) geometries. We find that the most important parameters that govern EDC are the rheological parameters mantle viscosity η0 and activation energy Ea. However, even the maximum melting volumes predicted by our most extreme cases are insufficient to account for island-building volcanism on old seafloor, such as at the Canary Islands and Cabo Verde. Also, beneath old seafloor, localized EDC-related melting commonly transitions into widespread melting due to small-scale sublithospheric convection, inconsistent with the distribution of volcanism at these volcano chains. In turn, EDC is a good candidate to sustain the formation of small seamounts on young seafloor, as it is a highly transient phenomenon that occurs in all our models soon after initiation. In a companion paper, we investigate the implications of interaction of EDC with mantle plume activity (Manjón-Cabeza Córdoba and Ballmer, 2021).

scholarly journals Combined numerical and experimental study of microstructure and permeability in porous granular media

2020 ◽  
Author(s):  
Philipp Eichheimer ◽  
Marcel Thielmann ◽  
Wakana Fujita ◽  
Gregor J. Golabek ◽  
Michihiko Nakamura ◽  
...  
Keyword(s):  
Fluid Flow ◽  
Numerical Simulations ◽  
Granular Media ◽  
Large Scale ◽  
Earth Science ◽  
Numerical Models ◽  
Effective Porosity ◽  
Flow Properties ◽  
Wide Range ◽  
Flow Through

Abstract. Fluid flow on different scales is of interest for several Earth science disciplines like petrophysics, hydrogeology and volcanology. To parameterize fluid flow in large-scale numerical simulations (e.g. groundwater and volcanic systems), flow properties on the microscale need to be considered. For this purpose experimental and numerical investigations of flow through porous media over a wide range of porosities are necessary. In the present study we sinter glass bead media with various porosities. The microstructure, namely effective porosity and effective specific surface, is investigated using image processing. We determine flow properties like hydraulic tortuosity and permeability using both experimental measurements and numerical simulations. By fitting microstructural and flow properties to porosity, we obtain a modified Kozeny-Carman equation for isotropic low-porosity media, that can be used to simulate permeability in large-scale numerical models. To verify the modified Kozeny-Carman equation we compare it to the computed and measured permeability values.

An Investigation of Tip Force Characteristics of Brush Seals

2007 ◽  
Author(s):  
Mehmet Demiroglu ◽  
Mustafa Gursoy ◽  
John A. Tichy
Keyword(s):  
Cantilever Beam ◽  
Numerical Models ◽  
Operating Conditions ◽  
Beam Equation ◽  
Labyrinth Seals ◽  
Wide Range ◽  
Brush Seals ◽  
Cantilever Beam Equation ◽  
Super Alloy ◽  
Force Pressure

Thanks to their compliant nature and superior leakage performance over conventional labyrinth seals, brush seals found increasing use in turbomachinery. Utilizing high temperature super-alloy fibers and their compliance capability these seals maintain contact with the rotor for a wide range of operating conditions leaving minimal passage for parasitic leakage flow. Consequently, the contact force/pressure generated at seal rotor interface is of importance for sustained seal performance and longevity of its service life. Although some analytical and numerical models have been developed to estimate bristle tip pressures, they simply rely on linear beam equation calculations and other such assumptions for loading cases. In this paper, previously available analytical and/or numerical models for bristle tip force/pressure have been modified and enhanced. The nonlinear cantilever beam equation has been solved and results are compared to a linear cantilever beam equation solution to establish application boundaries for both methods. The results are also compared to experimental data. With the support of testing, an empirical model has been developed for tip forces under operating conditions.

Rehabilitation: A Community Challenge

PEDIATRICS ◽  
1959 ◽  
Vol 23 (1) ◽  
pp. 131-131
Author(s):  
SEYMOUR S. BLUESTONE
Keyword(s):  
Significant Contribution ◽  
Rehabilitation Services ◽  
Community Activity ◽  
The Past ◽  
Wide Range ◽  
Basic Understanding ◽  
The Many

This volume collates knowledge accumulated, mainly during the past decade, by the many individuals and groups concerned with the provision of rehabilitation services. As one of the outstanding among these individuals, the author can speak authoritatively on the wide range of subjects covered. The book is well documented with references and is supplemented by an extensive classified bibliography. Intended "to form a source of reference and guidance for all those interested in (rehabilitation), particularly those at the planning level of community activity," the book should be of even wider interest as a significant contribution to the basic understanding of rehabilitation by all thinking people.

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