Techno-Economic Analysis and Feasibility Studies of Electric Vehicle Charging Station

Recent United Nations high-level dialogue on energy, which had emphasized on energy usage and environmental protection, has renewed commitments by different countries on the adoption of electric vehicle (EVs). This paper aims to analyze the economic feasibility of establishing electrical charging stations, which is an important factor for the wide adoption of EVs, using life cycle cost analysis. Although local data have been used, the method can be easily adopted to analyze economic feasibility at different markets. The findings have revealed that an electrical charging station is only feasible when the acquisition cost is kept to a minimum to return 1.47 times the initial investment in terms of life cycle cost. An acquisition cost of BND 29,725 on the electrical charging station represents the threshold below which an electrical charging station is more attractive. In order to promote these charging stations, the government needs to provide multiple incentives, including a subsidy to reduce the acquisition cost, relaxing control on the electric selling price, taxing the establishment of conventional filling stations, and minimally reducing the profit margin on the selling price of fossil fuel. It has been shown that a 40% initial subsidy on the purchase of electrical charging stations, coupled with a slight subsidy of BND 0.018/kWh on electricity, would make electrical charging stations economically competitive. To reach its target of 60% electrification of the transportation sector, Brunei would need to implement a structure program to establish between 646 and 3300 electrical charging stations by the year 2035, to cater for its expected number of EVs.

Value for Money: Guidance Note on Procurement

This guidance note discusses the principle of value for money (VFM) and its relevance and application to the different phases of the ADB procurement cycle. It also introduces “life cycle costing,” which takes into account not only the acquisition cost, but also a combination of paid price plus the cost of operating and maintaining the goods or services procured. The guidance note provides a matrix of the relationship of VFM with other ADB core procurement principles to give a better understanding of how VFM works with the other principles.

An integrated approach to evaluate different tetracycline derivatives for formulary decisions

Disclaimer In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Purpose Stenotrophomonas maltophilia has emerged as a critical opportunistic pathogen associated with significant morbidity and mortality. Tetracycline derivatives have been recognized as alternative treatment options, but they have varied pharmacokinetic properties. An integrated approach to different tetracycline derivatives for formulary decisions is reported. Methods The minimum inhibitory concentration (MIC) data from clonally diverse bloodstream S. maltophilia isolates were examined, along with the pharmacokinetic profiles of 4 tetracycline derivatives, to predict achievable pharmacodynamic exposures with standard intravenous dosing regimens. Antimicrobial therapy was assessed using the ratio of daily drug acquisition cost relative to the ratio of the free-drug area under the time-concentration curve (fAUC) to the 90th percentile for minimum inhibitory concentration (MIC) values for isolates (fAUC/MIC90). Results In our analysis, minocycline had the greatest fAUC/MIC90. Doxycycline was the most financially preferred agent, as calculated using 2020 average wholesale price for base-case estimates of drug acquisition cost. Conclusion An integrated evaluation for antimicrobial formulary decision-making addressed local susceptibility data, pharmacokinetics, pharmacodynamics, dosing regimens, and drug acquisition costs. This comprehensive method is more objective than the conventional approach and warrants validation.

Orchestrating Information Acquisition

We study how to orchestrate information acquisition in an environment where bidders endowed with original estimates (“types”) about their private values can acquire further information by incurring a cost. We consider both single-round and fully sequential short-listing rules. The optimal single-round shortlisting rule admits the set of most efficient bidders that maximizes expected virtual surplus adjusted by the second-stage signal and information acquisition cost. When shortlisting is fully sequential, at each round, the most efficient remaining bidder is admitted provided that her conditional expected contribution to the virtual surplus is positive. (JEL D44, D82, D83)

Extending subsurface imaging beyond ocean-bottom node coverage using multiples: A case study in deepwater Nigeria

We have evaluated the results of a receiver decimation study in a deepwater context using separated wavefield imaging (SWIM) algorithms to provide extended illumination for imaging without ocean-bottom node (OBN) positioning constraints. We carried out subsurface imaging using the SWIM imaging technique with a reduced OBN layout, and we compared the results with those from conventional one-way wave-equation migration. We found from the results that the SWIM algorithm makes it possible to reduce the OBN layout while obtaining a similar subsurface image with the same shot geometry, which allows a reduced receiver acquisition effort, offers more geometry flexibility without affecting the image quality, with a potentially significant reduction of acquisition cost and 4D processing turnaround time.

Cost-efficiency analysis of conversion from reference pegfilgrastim to its biosimilar (pegfilgrastim-jmdb) and expanded access to food and transportation support for Medicare/Medicaid patients within the CMS Oncology Care Model.

e18837 Background: The CMS Oncology Care Model (OCM) aims to improve quality of care and health outcomes in cancer centers at the same or lower cost. We performed cost-efficiency analyses of converting selected cancer patients (pts) from reference pegfilgrastim (PFG) to its biosimilar (PFG-jmdb); and simulated re-allocating savings to provide nutrition and transportation support to CMS beneficiaries within OCM. Methods: Incidence rates for breast, ovarian, lung, colorectal cancers and non-Hodgkin lymphoma were extracted from SEER, further stratified by age <65 (commercial insurance) or >65 (Medicare) adjusted for Medicare/Medicaid mix. Chemotherapy (CTX) rates were matched to tumor type; of these 19.4% were assumed to require PFG prophylaxis (PPX). Two models compared respectively prefilled syringe (PFS) and on-body injector (OBI) reference PFG to PFS PFG-jmdb. Cost inputs included Average Sales Price (ASP) 3Q20 for Medicare and National Average Drug Acquisition Cost (NADAC, estimated by wholesale acquisition cost (WAC)-3.9%) for Medicaid pts plus medication administration. Cost savings across various biosimilar conversion rates for CTX cycles 1-6 were translated into $100 units of healthy food or medical transportation. Results: In 2020, biosimilar conversion for the estimated 31,210 Medicare and 1,722 Medicaid pts in the 5 tumor types needing PFG PPX yielded savings of up to ̃$19M (Medicare) and ̃$20M (Medicaid). These savings could have provided a monthly $100 food or transportation check to at least 24,716 Medicare or 33,630 Medicaid pts for 6 months. Conclusions: Savings from biosimilar conversion can be re-allocated on a budget neutral basis to food and transportation support to pts with such needs. This achieves the dual OCM aim of reducing drug budgets while enhancing patient-centric support services.[Table: see text]

Convergence and Divergence Regarding Business Combinations

The presence of several legal entities within the same group entails the existence of as many independent accountants as there are companies. In accordance with IFRS 3 “business combinations,” the result is goodwill that will be recognized as a non-current intangible asset in the consolidated balance sheet, being subjected annually to the impairment test; insofar as the investment cost is lower than the acquisition cost of the net assets, the negative goodwill will be obtained which will be recognized in the form a profit in the consolidated profit and loss account. In addition, national differences in accounting, taxation, and auditing are the sources of the various problems that arise in the process of controlling subsidiaries and consolidating accounts. This chapter aims to study the convergence and divergence regarding business combinations in the joint business as well as to analyze the managerial controversies that are presented in the conversion of the financial statements.

Software for Static Equipment Budgeting of China’s Petrochemical Industry

We developed software by using Python language to reduce the manual work in the petrochemical budgeting process. Budget forms automatically generated by the software are based on the acquisition cost of items of static equipment and their installation fees. The software is also able to generate an Excel file that can be imported into the petrochemical aggregation software. This article explains the logic of the software based on the static equipment workflow in the current project. It provides development ideas to solve the problem of manually inputting equipment installation indexes, avoid confusion of equipment prices in the traditional estimate preparation process, and improve the work efficiency in the future.