The COVID-19 pandemic and the COVID-19 crisis have brought tremendous pressure on human beings and have raised deep concerns regarding the future of people's activities all over the world. The post-COVID-19 era presents a highly challenging perspective due to the uncertainties raised by the new environment, already weakened by the lack of cooperation among individuals, the ruthless competition between entities, and the fierce and aggressive decisions taken in haste, which affected the balance of our planet, the future of the next generations, and the well-being and mental health of people. Mindfulness represents a major solution to today's problems, offering individuals the possibility to become more focused, more connected with present situations, and more willing to understand not only their needs, but also the requirements of their colleagues, communities, and all that surrounds them. Mindfulness, as an investment in our lives, comes to support creativity, development, innovation, responsibility, sustainability, well-being, and a healthy and well-balanced business environment.