critical range
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2021 ◽  
Vol 12 (2) ◽  
Author(s):  
Florian Kokoszka ◽  
Daniele Iudicone ◽  
Adriana Zingone ◽  
Vincenzo Saggiomo ◽  
Maurizio Ribera D'Alcalá ◽  
...  

This is a short communication about the inter-annual recurring presence at the coastal site in the Gulf of Naples of density staircases visible below the mixed surface layer of the water-column, from the end of summer to the beginning of winter, each year during nearly two decades of survey (2001 to 2020). We repetitively observe sequences from 1 to 4 small vertical staircases structures (~ 3 m thick) in the density profiles (~ Δ0.2 kg.m-3), located between 10 m to 50 m deep below the seasonal mixed layer depth. We interpret these vertical structures as the result of double diffusive processes that could host salt-fingering regime (SF) due to warm salty water parcels overlying on relatively fresher and colder layers. This common feature of the Mediterranean basin (i.e., the thermohaline staircases of the Tyrrhenian sea) may sign here for the lateral intrusions of nearshore water masses. These stably stratified layers are characterized by density ratio Rρ 5.0 to 10.0, slightly higher than the critical range (1.0 - 3.0) generally expected for fully developed salt-fingers. SF mixing, such as parameterized (Zhang et al., 1998), appears to inhibit weakly the effective eddy diffusivity with negative averaged value (~ - 1e-8 m2.s-1). A quasi 5-year cycle is visible in the inter-annual variability of the eddy diffusivity associated to SF, suggesting a decadal modulation of the parameters regulating the SF regime. Even contributing weakly to the turbulent mixing of the area, we hypothesis that SF could influence the seasonal stratification by intensifying the density of deep layers. Downward transfer of salt could have an impact on the nutrient supply for the biological communities, that remains to be determined.


2021 ◽  
Vol 9 ◽  
Author(s):  
O. Korculanin ◽  
T. Kochetkova ◽  
M. P. Lettinga

Human blood is a shear-thinning fluid with a complex response that strongly depends on the red blood cell’s (RBC’s) ability to form aggregates, called rouleaux. Despite numerous investigations, microscopic understanding of the break up of RBC aggregates has not been fully elucidated. Here, we present a study of breaking up aggregates consisting of two RBCs (a doublet) during shear flow. We introduce the filamentous fd bacteriophage as a rod-like depletant agent with a very long-range interaction force, which can be tuned by the rod’s concentration. We visualize the structures while shearing by combining a home-build counter-rotating cone-plate shear cell with microscopy imaging. A diagram of dynamic states for shear rates versus depletant concentration shows regions of different flow responses and separation stages for the RBCs doublets. With increasing interaction forces, the full-contact flow states dominate, such as rolling and tumbling. We argue that the RBC doublets can only undergo separation during tumbling motion when the angle between the normal of the doublets with the flow direction is within a critical range. However, at sufficiently high shear rates, the time spent in the critical range becomes too short, such that the cells continue to tumble without separating.


2021 ◽  
pp. 1-16
Author(s):  
Mohamed Shafik Khaled ◽  
Hicham Ferroudji ◽  
Mohammad Azizur Rahman ◽  
Ibrahim Hasan Galal ◽  
A. Rashid Hasan

Summary Horizontal wells are designed to have smooth (straight), curved, and lateral sections. However, the actual drilled path usually suffers from unwanted undulations from the planned well trajectory known as wellbore tortuosity. Wellbore tortuosity can slow the drilling penetration rate, aggravate drillstring vibration and buckling, complicate the casing and cement job, and lead to inaccurate wellbore position. This paper presents a validated computational fluid dynamics (CFD) model to investigate the impact of wellbore tortuosity on hole cleaning. The Eulerian-Eulerian approach is used to simulate solid-liquid laminar flow in annular geometry using polyhedral mesh. Then, the impact of wellbore tortuosity on cuttings accumulation, annular pressure loss, and fluid velocity was investigated and compared with the flow behavior in a straight horizontal well. A parametric analysis of spiral period length, spiral amplitude, drillstring rotation, flow rate, annular eccentricity, drilling rate of penetration (ROP), and cuttings size was conducted to assess their influence on cuttings transport in spiral tortuous holes and their relative magnitude to other design or operating factors. Simulation results show that polyhedral mesh is an optimum meshing technique for spiral profile geometry. Wellbore tortuosity aggravates hole cleaning in lateral sections based on the length of the spiral period and/or the spiral amplitude. Reduction in cuttings velocity was observed in the top part of the spiral geometry (crest), causing large deposition of cuttings in this area compared to the spiral lower part (trough). Drillstring rotation from 0 to 200 rev/min is the critical range for efficient hole cleaning in spiral geometry. Cuttings size can improve cuttings accumulation if the particle size is larger than the viscous layer located near the bed velocity profile. The drilling ROP and annular eccentricity aggravate cuttings accumulation and bed deposition in a spiral hole, similar to what is normally observed in straight horizontal wells.


2021 ◽  
Vol 2021 ◽  
pp. 1-17
Author(s):  
Denghong Chen ◽  
Chao Li ◽  
Xinzhu Hua ◽  
Xiaoyu Lu ◽  
Yongqiang Yuan ◽  
...  

Taking the occurrence conditions of the hard main roof in the deep 13-1 coal mining roadway in Huainan mining area as the research object, based on the mechanical parameters of the surrounding rock and the stress state of the main roof obtained by numerical simulation, a simply supported beam calculation model was established based on the damage factor D, main roof support reaction RA, RB, and critical range C (9 m) and B (7 m) at the elastoplastic junction of the solid coal side and mining face side (hereinafter referred to as “junction”). Considering that the damage area still has a large bearing capacity, the vertical stress of the main roof at the junction is K1γH (0.05γh, 0.15γh, and 0.25γh) and K2γH (0.01γh, 0.10γh, and 0.2γh). The maximum deflection is 21 mm, 324 mm, and 627.6 mm, respectively. According to the criterion of tensile failure, the maximum bending moment of the top beam is 209 mN·m at the side of the working face 3.1 m away from the roadway side when K1 = 0.15 and K2 = 0.10, and the whole hard main roof is in tensile failure except the junction. To control the stability of the top beam and simplify the supporting reaction to limit the deformation of the slope angle, RC and RD are used to construct the statically indeterminate beam. By adding an anchor cable and advance self-moving support to the roadway side angle, the problem of difficult control of the surrounding rock with a large deformation of the side angle roof is solved, which provides a reference for roof control under similar conditions.


Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5199
Author(s):  
Pan Zheng ◽  
Wugui Jiang ◽  
Qinghua Qin ◽  
Duosheng Li

The molecular dynamics (MD) method is used to investigate the influence of the shielding gas on the dynamic behavior of the heterogeneous rotation transmission nano-system (RTS) built on carbon nanotubes (CNTs) and boron nitride nanotube (BNNT) in a helium environment. In the heterogeneous RTS, the inner CNT acts as a rotor, the middle BNNT serves as a motor, and the outer CNT functions as a stator. The rotor will be actuated to rotate by the motor due to the interlayer van der Waals effects and the end effects. The MD simulation results show that, when the gas density is lower than a critical range, a stable signal of the rotor will arise on the output and the rotation transmission ratio (RRT) of RTS can reach 1.0, but as the gas density is higher than the critical range, the output signal of the rotor cannot be stable due to the sharp drop of the RRT caused by the large friction between helium and the RTS. The greater the motor input signal of RTS, the lower the critical working helium density range. The results also show that the system temperature and gas density are the two main factors affecting the RTS transmission behavior regardless of the size of the simulation box. Our MD results clearly indicate that in the working temperature range of the RTS from 100 K to 600 K, the higher the temperature and the lower the motor input rotation frequency, the higher the critical working helium density range allows.


2021 ◽  
Vol 287 ◽  
pp. 112285
Author(s):  
Eleonora Grilli ◽  
Sílvia C.P. Carvalho ◽  
Tommaso Chiti ◽  
Elio Coppola ◽  
Rosaria D'Ascoli ◽  
...  

2021 ◽  
Vol 11 (10) ◽  
pp. 4681
Author(s):  
Mohammad Ebrahim Bajgholi ◽  
Gilles Rousseau ◽  
Martin Viens ◽  
Denis Thibault

This paper presents the results of a project aimed at evaluating the performance of ultrasonic techniques for detecting flaws in Francis turbine runners. This work is the first phase of a more ambitious program aimed at improving the reliability of inspection of critical areas in turbine runners. Francis runners may be utilized to supply power during peak periods, which means that they experience additional load stress associated with start and stop sequences. Inspection during manufacturing is then of paramount importance to remove as much as feasible all flaw initiation sites before the heat treatment. This phase one objective is to collect initial data on a simplified mock-up and then to compare the experimental ultrasonic data with the results of simulations performed by CIVA, a computer simulation package. The area of interest is the region with the highest stress between the blade and the web. A welded T-joint coupon made of UNS S41500 was manufactured to represent this high-stress area. During the FCAW welding process, ceramic beads were embedded in the weld to create discontinuities whose size is in the critical range to initiate a crack. Inspection of the material was carried out by various nondestructive testing (NDT) methods namely conventional pulse-echo, phased array, total focusing method (TFM). With these results, detection rates were obtained in order to compare the effectiveness of each method.


Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1232
Author(s):  
Manfred Wick ◽  
Catharina Gross ◽  
Hayrettin Tumani ◽  
Brigitte Wildemann ◽  
Martin Stangel ◽  
...  

The analysis of cells in the cerebrospinal fluid (CSF) is a routine procedure that is usually performed manually using the Fuchs–Rosenthal chamber and cell microscopy for cell counting and differentiation. In order to reduce the requirement for manual assessment, automated analyses by devices mainly used for blood cell analysis have been also used for CSF samples. Here, we summarize the current state of investigations using these automated devices and critically review their limitations. Despite technical improvements, the lower limit for reliable leukocyte counts in the CSF is still at approximately 20 cells/µL, to be validated depending on the device. Since the critical range for clinical decisions is in the range of 5–30 cells/µL this implies that cell numbers < 30/µL require a manual confirmation. Moreover, the lower limit of reliable erythrocyte detection by automated devices is at approximately 1000/µL. However, even low erythrocyte numbers may be of clinical importance. In contrast, heavily hemorrhagic samples from neurosurgery may be counted automatically at an acceptable precision more quickly. Finally, cell differentiation by automated devices provides only a rough orientation for lymphocytes, granulocytes and monocytes. Other diagnostically important cell types such as tumor cells, siderophages, blasts and others are not reliably detected. Thus, although the automation may give a gross estimate sufficient for the emergency room situation, each CSF requires a manual microscopy for cytological evaluation for the final report. In conclusion, although automated analysis of CSF cells may provide a first orientation of the cell profile in an individual sample, an additional manual cell count and a microscopic cytology are still required and represent the gold standard.


Utilitas ◽  
2021 ◽  
pp. 1-18
Author(s):  
Patrick Williamson

Abstract One prominent welfarist axiology, critical-level utilitarianism, says that individual lives must surpass a specified ‘critical level’ in order to make a positive contribution to the comparative status of a given population. In this article I develop a new dilemma for critical-level utilitarians. When comparatively evaluating populations composed of different species, critical-level utilitarians must decide whether the critical level is a universal threshold or whether the critical level is a species-relative threshold. I argue that both thresholds lead to a range of axiological puzzles and objections as yet undiscussed within the literature, and therefore conclude that critical-level utilitarianism should not be taken as a morally plausible welfarist axiology. I show that certain competitive formulations of critical range utilitarianism are subject to the argument too, and that further attempts to relativise critical levels to a particular group or category of welfare bearer (in particular, individual-relative critical levels) are unsustainable.


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