Because of rapid urbanization, traffic problems, and other factors, underground spaces have been used more in the twenty-first century. Large underground spaces are required for underground city, metro, tunnel, mine, industrial and agricultural engineering, and civil air defense engineering. Underground spaces with varying thermal, ventilation, and lighting environments can face problems of comfort, health, and safety. High temperatures, high humidity, difficulty in flue gas emission, harmful microorganisms, radon, and physical and psychological problems are examples of issues. Air quality control technologies for underground spaces, such as ventilation, dehumidification, natural energy utilization, smoke extraction, and ventilation resistance reduction, are discussed. Ventilation for smoke-proofing/evacuation is also extensively addressed.