Rapid Initial Morphospace Expansion and Delayed Morphological Disparity Peak in the First 100 Million Years of the Archosauromorph Evolutionary Radiation

Adaptive radiations have played a major role in generating modern and deep-time biodiversity. The Triassic radiation of the Archosauromorpha was one of the most spectacular vertebrate radiations, giving rise to many highly ecomorphologically varied lineages—including the dinosaurs, pterosaurs, and stem-crocodylians—that dominated the larger-bodied land fauna for the following 150 Ma, and ultimately gave rise to today’s > 10,000 species of birds and crocodylians. This radiation provides an outstanding testbed for hypotheses relating to adaptive radiations more broadly. Recent studies have started to characterize the tempo and mode of the archosauromorph early adaptive radiation, indicating very high initial rates of evolution, non-competitive niche-filling processes, and previously unrecognized morphological disparity even among non-crown taxa. However, these analyses rested primarily either on discrete characters or on geometric morphometrics of the cranium only, or even failed to fully include phylogenetic information. Here we expand previous 2D geometric morphometric cranial datasets to include new taxa and reconstructions, and create an analogous dataset of the pelvis, thereby allowing comparison of anatomical regions and the transition from “sprawling” to “upright” posture to be examined. We estimated morphological disparity and evolutionary rates through time. All sampled clades showed a delayed disparity peak for sum of variances and average nearest neighbor distances in both the cranium and pelvis, with disparity likely not saturated by the end of the studied time span (Late Jurassic); this contrasts with smaller radiations, but lends weight to similar results for large, ecomorphologically-varied groups. We find lower variations in pelvic than cranial disparity among Triassic-Jurassic archosaurs, which may be related to greater morphofunctional constraints on the pelvis. Contrasting with some previous work, but also confirming some previous findings during adaptive radiations, we find relatively widespread evidence of correlation between sampled diversity and disparity, especially at the largest phylogenetic scales and using average displacement rather than sum of variances as disparity metric; this also demonstrates the importance of comparing disparity metrics, and the importance of phylogenetic scale. Stem and crown archosauromorphs show a morphological diversification of both the cranium and pelvis with higher initial rates (Permian–Middle Triassic and at the base of major clades) followed by lower rates once diversification into niches has occurred (Late Triassic–Jurassic), indicating an “early burst” pattern sensu lato. Our results provide a more detailed and comprehensive picture of the early archosauromorph radiation and have significant bearing on the understanding of deep-time adaptive radiations more broadly, indicating widespread patterns of delayed disparity peaks, initial correlation of diversity and disparity, and evolutionary early bursts.

521 Incidence of Bone Fracture Rate Post-Burn and Trauma in Role 2 and 3 Treatment Centers

Introduction One of the hallmarks of critical illness and trauma is that it triggers resorptive bone loss, as well as an increase in bone fractures and a reduction in bone density. Sustained markers of bone resorption, bone formation, and regulators of bone signaling pathways are linked to prolonged inflammatory activities and the prolonged deterioration of bone microstructure. The objective of this study is to evaluate the bone fracture rate of the U.S Military, non-U.S. Military, North Atlantic Treaty Organization (NATO) Military, local civilian, and Coalition Forces population in Operation Enduring Freedom and Operation Freedom’s Sentinel with burns from 2005 to 2018 using the Department of Defense Trauma Registry (DoDTR; n=28,707). Our hypothesis is that there is a direct relationship between burn injury severity and bone fracture rates. Methods Pearson’s correlation coefficient and scatterplots were used in this retrospective, observational study to demonstrate the correlation between total body surface area (TBSA) burn and number of fractures by anatomical location. Results Approximately 15,195 patients (age: 26 ± 10 years) in Role 2 and Role 3 treatment centers reported fractures. Of those patients, 351 suffered from burns with 632 anatomical fracture locations. Facial fractures were most prominent (16%), followed by foot (12%), skull (12%), tibia/fibula (11%), hand (11%), and ulna/radius (10%). There was no initial correlation between n increasing severity of TBSA burn and count of fracture locations (ρ=-0.03, p=0.8572). Conclusions There was no acute correlation between burn severity and bone fracture rates; however, further analyses are required to assess chronic post-burn fracture rates.

Progestogen metabolites for use in pregnancy monitoring of 13-lined ground squirrels (Ictidomys tridecemlineatus)

Graphical abstract 13-lined ground squirrels (TLGS; Ictidomys tridecemlineatus) are small, omnivorous, fossorial, hibernating sciurids. TLGS are seasonal induced ovulators, with a ~28-day gestation period. The main goal of this study was to ascertain whether enzyme-linked immunosorbent assay (ELISA) of TLGS fecal samples can be used to non-invasively detect pregnancy. Competitive ELISAs for progestogen metabolites were conducted on feces collected from a group of (n =13) females. Feces were collected thrice weekly during the breeding season and frozen for subsequent analysis. Competitive ELISAs were run using progesterone kits ), setting data against seven different time-points between hibernation, emergence, and litter birthdate. Eleven females produced litters. ELISA data from the (n = 2) non-pregnant females demonstrated no rise in progestogen metabolites at any point over 28 days. In contrast, data from the (n = 11) pregnant females all demonstrated a pronounced rise in progestogen metabolites, with most animals displaying progesterone withdrawal in the final week of gestation. A >20-fold rise in progestogen metabolite was observed halfway through gestation (P < 005). Analysis on litter size and progestogen metabolite concentration showed no significant correlation (r2 = −0.615). Initial correlation analysis done on sex ratio of litters vs progestogen metabolites showed no significant effect of progesterone on sex ratios (males: r2 = −0.772, females: r2 = 0.375). This work demonstrated that TLGS also undergo progesterone withdrawal about a week before parturition. We have ascertained that a commercially available progesterone assay kit can detect a significant elevation in progestogen metabolites in this species about halfway through gestation. Lay summary This research was conducted to discover whether pregnancy prediction is possible in female 13-lined ground squirrels (TLGS; a small hibernating ground squirrel named for their number of stripes). Pregnancy status in this species, we postulated, could be anticipated by generating profiles for individuals via a non-invasive technique known as fecal endocrine hormone profiling. Fecal samples were collected from 13 females thrice weekly for 4 weeks post-hibernation in the breeding season of 2016. Fecal samples were then processed and run through an assay known as an ELISA giving concentrations of hormone metabolites excreted through feces. We then set these samples against time points to develop a profile for each female. We have ascertained that elevated progesterone (potential pregnancy) can be detected by a commercially available assay kit. Understanding hormone patterns in animals gives researchers a better idea of best husbandry practices, including breeding in managed care.

Dynamical decoupling with initial system-environment correlations

Dynamical decoupling (DD) technique is one of the most successful methods to suppress decoherence in qubit systems. In this paper, we studied a solvable pure dephasing model and investigated how DD sequences and initial correlations affect this system. We gave the analytical expressions of decoherence functions and compared the decoherence suppression effects of DD pulses in Ohmic, sub-Ohmic and super-Ohmic environments. Our results show that (1) The initial system-environment correlation will cause additional decoherence. In order to control the dynamic process of open quantum system more accurately and effectively, the initial correlation between the system and reservoir must be considered. (2) High frequency DD pulses can significantly reduce the amplitude of the decoherence function even in the presence of initial system-environment correlations.

PENINGKATAN KOMPETENSI PAEDAGOGIK GURU DALAM PENYUSUNAN PERENCANAAN PEMBELAJARAN MELALUI SUPERVISI AKADEMIK DI MADRASAH IBTIDAIYAH SWASTA TIMBANG LAWAN BOHOROK

The writing of this School Action Research (PTS) was carried out by researchers of 9 educators (teachers) which consisted of 2 cycles by implementing the Improvement of Teacher's Pedagogical Competence in Preparing Learning Plans through Academic Supervision Can Improve the Quality of Teaching Teachers at Private Madrasah Ibtidaiyah Weigh Against Bohorok, The report on the results of the calculation of the Teacher's Learning Planning Ability about the initial correlation to the first cycle of 0.738 and the t test value of 4.283, as well as the calculation of the correlation of the first cycle to the second cycle of 0.921 and the t test value of 16.156 and the results of the calculation of the Learning Planning Component about the initial correlation to the first cycle of 0.713 and the value of the t test of 2.507, the calculation of the correlation between the first cycle and the second cycle is 0.875 and the t test value is 6.466. As well as the Improvement of Teacher's Pedagogical Competence in Preparing Learning Planning through Academic Supervision Getting Student Learning Outcomes at Private Madrasah Weigh Against Bohorok, with reports on the results of the calculation of the Average value of 9 Subjects about the initial correlation to the first cycle of 0.778 and the t-test value of 5.222 and calculations. The correlation between the first cycle and the second cycle is 0.934, and the t test value is 19.293. All calculation results show a significant value. Keywords: Teacher Pedagogic Competence, Learning Planning Compilation, Academic Supervision, Teacher Teaching Quality

Climate effect on COVID-19 spread rate: an online surveillance tool

BackgroundCOVID-19 outbreak poses an unprecedented challenge for societies, healthcare organizations and economies. In the present analysis we coupled climate data with COVID-19 spread rates worldwide, and in a single country (USA).MethodsData of confirmed COVID-19 cases was derived from the COVID-19 Global Cases by the CSSE at Johns Hopkins University up to March 19, 2020. We assessed disease spread by two measures: replication rate (RR), the slope of the logarithmic curve of confirmed cases, and the rate of spread (RoS), the slope of the linear regression of the logarithmic curve.ResultsBased on predefined criteria, the mean COVID-19 RR was significantly lower in warm climate countries (0.12±0.02) compared with cold countries (0.24±0.01), (P<0.0001). Similarly, RoS was significantly lower in warm climate countries 0.12±0.02 vs. 0.25 ± 0.01 than in cold climate countries (P<0.001). In all countries (independent of climate classification) both RR and RoS displayed a moderate negative correlation with temperature R= -0.69, 95% confidence interval [CI], -0.87 to -0.36; P<0.001 and R= -0.72, 95% confidence interval [CI], -0.87 to -0.36; P<0.001, respectively. We identified a similar moderate negative correlation with the dew point temperature. Additional climate variables did not display a significant correlation with neither RR nor RoS. Finally, in an ancillary analysis, COVID-19 intra-country model using an inter-state analysis of the USA did not identify yet correlation between climate parameters and RR or RoS as of March, 19, 2020.ConclusionsOur analysis suggests a plausible negative correlation between warmer climate and COVID-19 spread rate as defined by RR and RoS worldwide. This initial correlation should be interpreted cautiously and be further validated over time, the pandemic is at different stages in various countries as well as in regions within these countries. As such, some associations may be more affected by local transmission patterns rather than by climate. Importantly, we provide an online surveillance dashboard (https://covid19.net.technion.ac.il/) to further assess the association between climate parameters and outbreak dynamics worldwide as time goes by.Research in contextEvidence before this studyThe coronavirus, COVID-19 pandemic caused by the novel SARS-CoV 2, challenges healthcare organizations and economies worldwide. There have been previous reports describing the association between seasonal climactic variance and SARS-CoV 1 as well as the MERS infections, but the association with SARS-CoV 2 and climate has not been described extensively.Added value of this studyOur analysis demonstrates a plausible negative correlation between warmer climate and COVID-19 spread rate as defined by RR and RoS worldwide in all countries with local transmission as of March 9, 2020. This initial correlation should be interpreted cautiously and be further validated over time. Importantly, we provide an online surveillance dashboard available at (https://covid19.net.technion.ac.il/) for further dynamic tracking of climate effect on COVID-19 disease spread rate worldwide and on intra-country analysis between USA states.Implications of all the available evidenceOur findings of decreased replication and spread rates of COVID-19 in warm climates may suggest that the inevitable seasonal variance will alter the dynamic of the disease spread in both hemispheres in the coming months. However, we warrant a cautious interpretation of these findings given the fact that we are in the initial steps of this outbreak in many “warm” climate countries, the high variance of the data and the dynamic changes in the disease surveillance and the lack of correlation based on the limited data in the US. We hope that the online tool coupling COVID-19 data with climate data will assist in tracking the disease and tailoring the needed measures to contain it.

Religious community in modern cultural space: transformation of identity and memorial practices

This article discusses the problem of transformation of memorial practices of religious community in the context of modern cultural space. The subject of research is the memorial practices of religious communities, while the main goal is to determine their specificity in terms of intensification of post-secular trends and individualization of culture. The author reveals the initial correlation of religious community with the processes of maintaining collective identity and the ways of preserving collective remembrances; and later analyzes the process of their changeability, highlights the development stages and fundamental characteristics of religious communities. Based on functional approach proposed by E. Durkheim, M. Halbwachs and D. Hervieu-L&eacute;ger, the article analyzes the situation of transformation of functions of collective memory and ways of referring to it in the context of spatial dynamics. The author&rsquo;s main contribution consists in determination of transformation stages of the cultural space (culture of canon, culture of trauma, culture of dialogue), which allows indicating the prerequisites for secularization of memorial practices, as well as possibility for their studying in the context of post-secular trends. The conclusion is formulated that in modern culture, the religious community is established on the principles of individualization, homogenization and migration, which implies the refusal of presumption of continuity of collective memory, and transition towards its interpretation as a configurable element of the identity of religious community. The emerging gap between the need in religious beliefs and affiliation to the tradition creates a social request for the formation of local religious communities.

A new methodology to create valid time-dependent correlation matrices via isospectral flows

In many areas of finance and of risk management it is interesting to know how to specify time-dependent correlation matrices. In this work we propose a new methodology to create valid time-dependent instantaneous correlation matrices, which we called correlation flows. In our methodology one needs only an initial correlation matrix to create these correlation flows based on isospectral flows. The tendency of the time-dependent matrices can be controlled by requirements. An application example is presented to illustrate our methodology.

COVID-19 lockdown in Poland – changes in regional and local mobility patterns based on Google Maps data

As no effective treatment or vaccine have yet been developed, the only way to prevent the spread of SARS-Cov-2 is to introduce social distancing measures. Scientific discussion regarding their actual effectiveness and socio-economic consequences has only just begun. Both declining mobility and changes in mobility patterns are obvious effects of social distancing. The main objective of this article is to present spatial diversity of changes in regional and local mobility in Poland with the use of data gathered and provided by Google LCC. As for the regional dimension, the mobility has declined steadily in most of the analysed areas. The regional changes were more visible only in the case of the following categories of areas: grocery & pharmacy and parks. The initial correlation analysis has shown that distribution of those changes more or less reflects spatial voting patterns. Both historical and cultural factors may explain such results, including ingrained habits, collective attitudes towards politics and group values. In the local context, illustrated by the analysis of changes in travel time from housing areas in Gdańsk, Gdynia and Sopot to the business and science centre in Gdańsk-Oliwa, a noticeable yet spatially diversified decrease in drive time (by private car) has been observed. The most significant reduction in travel time was recorded in peripheral areas accessible by high-speed roads which are normally jammed during peak hours. The mobility constraints have led to highly reduced traffic congestion, and consequently, shortened the travel time.