Antimonopoly Compliance: Review of Foreign Practice. Part I

The article contains the best foreign practices of implementing the of antimonopoly compliance Institute (compliance) in order to identify and manage the risks of violations of competition law and the possibility of preventing these violations by companies. The article presents the definition of compliance, describes the experience of foreign competition authorities in development, organization and implementation of compliance programs. Special attention is paid to the potential benefits that business receives as part of the successful implementation of the antimonopoly compliance system, including the possibility of mitigating circumstance in case a company commits an antimonopoly offense.

Compliance-Driven Cybersecurity Planning Based on Formalized Attack Patterns for Instrumentation and Control Systems of Nuclear Power Plants

The instrumentation and control (I&C) system of a nuclear power plant (NPP) employs a cybersecurity program regulated by the government. Through regulation, the government requires the implementation of security controls in order for a system to be developed and operated. Accordingly, the licensee of an NPP works to comply with this requirement, beginning in the development phase. The compliance-driven approach is efficient when the government supervises NPPs, but it is inefficient when a licensee constructs them. The security controls described in regulatory guidance do not consider system characteristics. In other words, the development organization spends a considerable amount of time excluding unnecessary control items and preparing the evidence to justify their exclusion. In addition, security systems can vary according to the developer’s level of security knowledge, leading to differences in levels of security between systems. This paper proposes a method for a developer to select the appropriate security controls when preparing the security requirements during the early development phase; it is designed to ensure the system’s security and reduce the cost of excluding unnecessary security controls. We have formalized the representation of attack patterns and security control patterns and identified the relationships between these patterns. We conducted a case study applying RG 5.71 in the Plant Protection System (PPS) to confirm the validity of the proposed method.

Circulating MicroRNAs for Diagnosis of Acute Pulmonary Embolism: Still a Long Way to Go

Venous thromboembolism (VTE) represents the third most frequent cause of acute cardiovascular syndrome. Among VTE, acute pulmonary embolism (APE) is the most life-threatening complication. Due to the low specificity of symptoms clinical diagnosis of APE may be sometimes very difficult. Accordingly, the latest European guidelines only suggest clinical prediction tests for diagnosis of APE, eventually associated with D-dimer, a biomarker burdened by a very low specificity. A growing body of evidence is highlighting the role of miRNAs in hemostasis and thrombosis. Due to their partial inheritance and susceptibility to the environmental factors, miRNAs are increasingly described as active modifiers of the classical Virchow’s triad. Clinical evidence on deep venous thrombosis reported specific miRNA signatures associated to thrombosis development, organization, recanalization, and resolution. Conversely, data of miRNA profiling as a predictor/diagnostic marker of APE are still preliminary. Here, we have summarized clinical evidence on the potential role of miRNA in diagnosis of APE. Despite some intriguing insight, miRNA assay is still far from any potential clinical application. Especially, the small sample size of cohorts likely represents the major limitation of published studies, so that extensive analysis of miRNA profiles with a machine learning approach are warranted in the next future. In addition, the cost-benefit ratio of miRNA assay still has a negative impact on their clinical application and routinely test.

A systematic characterization of intrinsically formed microglia-like cells during retinal organoid differentiation.

Brain organoids differentiated from human induced pluripotent stem cells provide a unique opportunity to investigate the development, organization and connectivity of neurons in a complex cellular environment. However, organoids usually lack microglia, brain-resident immune cells which are both present in the early human embryonic brain and participate in neuronal circuit development. Here, we find that microglia innately develop in unguided retinal organoid differentiation between week 3 and 4 in 2.5D culture and appear later in floating, non-pigmented, 3D-cystic compartments. We enriched for cystic structures using a low-dosed BMP4 application and performed mass spectrometry, thus defining the protein composition of microglia-containing compartments. We found that cystic compartments expressed both mesenchymal and epithelial markers with microglia enriched in the mesenchymal region. Interestingly, microglia-like cells started to express the border-associated macrophage marker CD163. The preferential localization of human microglia to a mesenchymal compartment provides insight into the behavior and migration of microglia. The model will ultimately allow detailed study of these enigmatic cells and how they enter and distribute within the human brain.

Mentoring in Medicine (MIM): Motivating and enabling disadvantaged youth to become the next generation of minority health professionals

Mentoring in Medicine, Inc (MIM) is a nonprofit health and science youth development organization based in the Bronx, NY. Founded in 2006 by three physicians and an engineer- trained entrepreneur, MIM’s organizational goal is to expose socioeconomically disadvantaged students to the wide variety of health and science careers and to increase the health literacy of their communities. It is aligned with the outreach mission of the U.S. National Library of Medicine (NLM) whose former Director, Donald A.B. Lindberg M.D., fostered an enduring relationship. Technical assistance, evaluation, and financial support provided under his leadership helped MIM to become a nationally recognized organization leading the field to diversify health careers and to increase health literacy in often hard to reach populations. Through live and virtual programming, MIM has impacted nearly 58,000 students, parents, and educators in urban epicenters in the U.S. The MIM Team has helped 503 students who were discouraged to build a competitive application and matriculate in health professional school. MIM has 88 press features highlighting its work in the community.

BRAND MANAGEMENT IN STRATEGIC ENTERPRISE MANAGEMENT

Branding is an integral part of an enterprise's marketing activities and can be analyzed in various aspects. Brand management – is the process of creating and managing a brand that is based primarily on the sale of goods. The main components in this process are brand ideas, market analysis, strategy development, organization of an advertising company. In addition, to date, branding policy is one of the elements of marketing, it determines the positions of other types of policy, because today the role of brand for the enterprise is a determining factor of competitiveness and survival of the enterprise in the market. When forming a brand, it is necessary to formulate problems related to needs, supply and demand, as they fully reflect the specifics of the functioning of the product market. The process of brand management is differentiated into blocks; methods for determining the brand value of an enterprise are proposed. The prerequisites for changing brand management are related to the processes and cycles that occur in the economy such as: globalization of business, development of scientific and technological progress, changes in the external environment and society, and even the expansion of market boundaries, so a comparison of the dynamics of brand- enterprise management; brand management concepts are compared. The strategic brand management process is important for creating and maintaining brand equity. Developing a strategy that successfully supports or enhances brand awareness, strengthens brand associations, emphasizes brand quality and use, is part of brand management. In today's world, in order to maintain a competitive position, every leader must first and foremost consider the value of his or her brand in developing its strategy and pay attention to branding and find key points for winning the position.

أثر التدريب الإداري على تنمية الموارد البشرية بالمنظمات الخدمية دراسة حالة: مجموعة شركات سواداتل للاتصالات المحدودة[. 2005 - 2012

This study seeks to determine the impact of management training effective human resource development organizations service was taking a case study group of companies Sudatel Telecom Limited and The importance of this study of the importance of training and its role in the development and enhance the performance of human resource, the methodology used in this research historical approach goal in Show Previous studies and access to books and scientific references relevant to the subject of the study, and deductive approach and the descriptive goal in the description of the questionnaire used in the study and finally the analytical method based inferential test the validity of the study hypotheses using appropriate statistical tests, This study contains five chapters, the first chapter contains five sections, as well as Chapter II also contains five sections The third chapter contains three sections, Chapter IV contains the organizations subject of study and action field study, Chapter V includes statistical analysis of the questionnaires and then the results and recommendations, the study finds to several results, most important is the training of management concepts ancient however still organizations floundering in terms of subservience administrative has fallen dependency training to the Director General and to manage the affairs of individuals and at other times to administrative affairs and that the lack of a training plan and a clear offset budget enough, which led to reduce the importance of training and marginalize its role in human resource development organization, in spite of the multiplicity and difference accepted notions about training they all agree in content and purpose of the training, it is planned and organized activity aimed at developing the skills and capabilities of individuals and boost their productivity, the study concludes several recommendations of the most important education administrative leadership and guidance in service organizations towards the concept and importance of effective management training in the development of human resources, the need for attention to the provision of financial means and material resources for the training process and the need to consider training among the strategic priorities in these organizations.

Relationship between employee well-being and organizational health: symbiotic or independent?

Purpose The purpose of this study is to understand the bi-directional causal relationship (regular and reverse causation) between employee well-being and organizational health, which is grounded in the micro-foundations of institutional theory. Design/methodology/approach In this study, employee well-being has two facets: work engagement and burnout. The positive aspect of employee well-being has been conceptualized by work engagement, whereas the negative aspect has been conceptualized with the help of burnout. As concurrent triangulation method was adopted, the qualitative data, as well as quantitative data, was collected from various laboratories of Council of Scientific and Industrial Research – an Indian research and development organization. Findings The findings did not show the existence of a symbiotic relationship between employee well-being and organizational health. The findings indicated the existence of a significant positive relationship between organizational health and employee well-being, but the reverse effect was found to be non-significant. This shows that when organizational health is good, employees’ health will also be good but not vice versa. Originality/value This study shows that health is not a static state, and so, at any given point in time, employee well-being cannot have a positive relationship with organizational health. Employee engagement helps enhance organizational health, whereas burnout can hinder organizational health if not properly mitigated.

Methods of Developing Sustainable Competitiveness Indicators for Innovative Industrial Clusters

The present article introduces a new system of indicators for assessing the sustainable competitiveness of innovative industrial clusters. The authors reviewed foreign and domestic approaches to monitoring and evaluating industrial clusters and classified them according to assessment type, research level, costs, and effects. Sustainable competitiveness proved to be the most complex characteristic of any cluster. It could be divided into two groups of parameters, i.e. 1) long-term competitiveness and 2) stability as a socio-ecological and economic system. Each group was given a list of indicators for quantitative and qualitative assessment, which included indicators of potential development, organization and management, socio-ecological and economic stability, etc. The research revealed some gaps in the Russian statistics of cluster development, which hinder the information support for monitoring and evaluating the sustainable competitiveness of clusters. As a result, the current databases on the social, economic, and environmental aspects of Russian clusters are fragmented and chronologically incompatible.

The Technopolitics of Mapping Dar es Salaam: An examination of the technological and political motivations of the Humanitarian OpenStreetMap Team

Mapping has long formed a key part of development work, from recording household surveys, participatory mapping exercises, and PRA projects. Now though the sector is full of new actors- mapping and tech companies as well as NGOs- monitoring through drones and satellite images, alongside employing more traditional methods. Many of these new players were born from NGOs and companies who started as ‘crisis mappers. Short-term ‘crisis mapping’ projects have become a regular part of humanitarian response following a disaster. The short-term nature of such actions, and the need for stable employment/profits, has led to an increasing trend for the same organizations and companies to either remain on the ground producing maps or to move into new areas as part of a pre-emptive mapping practice, inserting themselves into the wider international development ecosystem. This research, centered on Tanzania, examines how HOTOSM has attempted to pivot towards working as a development organization that creates maps for prevention of crisis, but also wider socio-economic outputs. The research used interviews to explore the interplay between technology and micro/macro politics around the mapping of Dar es Salaam. Examining how HOTOSM its role, and how they position their map-making within the context of Dar es Salaam. Findings suggest that HOTOSM is still underdeveloped as an organization and lacks the maturity to create true participatory models of working.