Cortical sensorimotor activity in the execution and suppression of discrete and rhythmic movements

Although the engagement of sensorimotor cortices in movement is well documented, the functional relevance of brain activity patterns remains ambiguous. Especially, the cortical engagement specific to the pre-, within-, and post-movement periods is poorly understood. The present study addressed this issue by examining sensorimotor EEG activity during the performance as well as STOP-signal cued suppression of movements pertaining to two distinct classes, namely, discrete vs. ongoing rhythmic movements. Our findings indicate that the lateralized readiness potential (LRP), which is classically used as a marker of pre-movement processing, indexes multiple pre- and in- movement-related brain dynamics in a movement-class dependent fashion. In- and post-movement event-related (de)synchronization (ERD/ERS) observed in the Mu (8–13 Hz) and Beta (15–30 Hz) frequency ranges were associated with estimated brain sources in both motor and somatosensory cortical areas. Notwithstanding, Beta ERS occurred earlier following cancelled than actually performed movements. In contrast, Mu power did not vary. Whereas Beta power may reflect the evaluation of the sensory predicted outcome, Mu power might engage in linking perception to action. Additionally, the rhythmic movement forced stop (only) showed a post-movement Mu/Beta rebound, which might reflect an active "clearing-out" of the motor plan and its feedback-based online control. Overall, the present study supports the notion that sensorimotor EEG modulations are key markers to investigate control or executive processes, here initiation and inhibition, which are exerted when performing distinct movement classes.

Evaluation of Strategies to Improve the Corporate Social Responsibility Performance in Food and Pharmaceutical Industries: Empirical Evidence from Iran

Since there is a lack of a strong CSR platform in the Iranian corporate environment, especially in the food and pharmaceutical industries, the proposed and existing strategies can be utilized to empower employees and the general public, improve executive processes, improve quality and customer satisfaction, and finally, organize financial and accounting reports. Hence, this study seeks to determine and evaluate strategies to improve the concepts and domain of corporate social responsibility (CSR) of food and pharmaceutical industries in Iran based on the requirements of sustainable development theory. This study analyzes the data of 22 companies active in the food and pharmaceutical industries listed on the Tehran Stock Exchange (TSE) over a period of six years (2014–2019). Eighty-three indicators were used to evaluate the performance of social responsibility based on economic, social and environmental dimensions. The Pareto approach has been used to determine the most important unmet current requirements. Then, using the Delphi method and content validity, appropriate strategies were determined. Finally, a correlation matrix was used to determine the most important and comprehensive strategies. Findings showed that 14 requirements in the field of corporate social responsibility are of great importance and with six strategies, the necessary measures to meet those requirements can be covered.

Determination of Evaluation Indicators and Establishment of Employees Performance Evaluation System

Employees’ performance appraisal can be seen as an intersection between employees and organizations’ expectations. The two main tasks in evaluating employees’ performance are the establishment of a system for evaluating performance, and the preparation of supervisors to play an effective role within the system and related executive processes.

Cardiovascular risk moderates the effect of aerobic exercise on executive functions in older adults with subcortical ischemic vascular cognitive impairment

Aerobic training (AT) can promote cognitive function in adults with Subcortical Ischemic Vascular Cognitive Impairment (SIVCI) by modifying cardiovascular risk factors. However, pre-existing cardiovascular health may attenuate the benefits of AT on cognitive outcomes in SIVCI. We examined whether baseline cardiovascular risk moderates the effect of a 6-month progressive AT program on executive functions with a secondary analysis of a randomized controlled trial in 71 adults, who were randomized to either: (1) 3×/week progressive AT; or (2) education program (CON). Three executive processes were measured: (1) response inhibition by Stroop Test; (2) working memory by digits backward test; and (3) set shifting by the Trail Making Test. Baseline cardiovascular risk was calculated using the Framingham cardiovascular disease (CVD) Risk Score (FCRS), and participants were classified as either low risk (< 20% FCRS score; LCVR) or high risk (≥ 20% FCRS score; HCVR). A complete case analysis (n = 58) was conducted using an analysis of covariance (ANCOVA) to evaluate between-group differences in the three executive processes. A significant interaction was found between cardiovascular risk group and intervention group (AT or CON) for the digit span backward and the Trail Making Test. AT improved performance compared with CON in those with LCVR, while in those with HCVR, AT did not improve performance compared with CON. Baseline cardiovascular risk significantly moderates the efficacy of AT on cognition. Our findings highlight the importance of intervening early in the disease course of SIVCI, when cardiovascular risk may be lower, to reap maximum benefits of aerobic exercise.

Cortical sensorimotor activity in the execution and suppression of discrete and rhythmic movements

Although the engagement of sensorimotor cortices in movement is well documented, the functional relevance of brain activity patterns remains ambiguous. Especially, the cortical engagement specific to the pre-, within-, and post-movement periods is poorly understood. The present study addressed this issue by examining sensorimotor EEG activity during the performance as well as STOP-signal cued suppression of movements pertaining to two distinct classes, namely, discrete vs. ongoing rhythmic movements. Our findings indicate that the lateralized readiness potential (LRP), which is classically used as a marker of pre-movement processing, indexes multiple pre- and in-movement-related brain dynamics in a movement-class dependent fashion. In- and post-movement event-related (de)synchronization (ERD/ERS) observed in the Mu (8-13 Hz) and Beta (15-30 Hz) frequency ranges were associated with estimated brain sources in both motor and somatosensory cortical areas. Notwithstanding, Beta ERS occurred earlier following cancelled than actually performed movements. In contrast, Mu power did not vary. Whereas Beta power may reflect the evaluation of the sensory predicted outcome, Mu power might engage in linking perception to action. Additionally, the rhythmic movement forced stop (only) showed a post-movement Mu/Beta rebound, which might reflect an active “clearing-out” of the motor plan and its feedback-based online control. Overall, the present study supports the notion that sensorimotor EEG modulations are key markers to investigate control or executive processes, here initiation and inhibition, which are exerted when performing distinct movement classes.

Faux Pas Recognition and Executive Processes in Patients with Alcohol Use Disorder: Toward an Investigation of Interindividual Heterogeneity

Objective Impairment of executive functions (EF) has been documented for decades in patients with alcohol use disorders (AUD), while more recent studies have also reported impaired theory of mind. Both have been associated with negative outcomes, particularly a high risk of relapse. However, the interrelatedness of EF and theory of mind impairments remains subject to debate. Method About 19 AUD outpatients and 20 healthy controls (HC) were asked to complete measures of motor inhibition, mental flexibility, and updating to assess EF, and the faux pas test to assess theory of mind. Results As expected, patients’ mean performances on EF and faux pas measures were poorer than those of HC. Correlational analyses revealed that executive processes were differentially related to faux pas subscores. Additional single-case analyses corroborated the strong association between EF and faux pas interpretation, as patients with AUD mostly had congruent performances (i.e., both EF and faux pas impaired or both EF and faux pas preserved). Conclusions This study highlights the interrelatedness of EF and faux pas performances in AUD, but also emphasizes the incomplete overlap of the cognitive processes involved in these tasks, with heterogeneous patterns of association. Based on these findings, tailored cognitive rehabilitation programs that simultaneously target EF and faux pas recognition could be developed to favor patients’ social inclusion and reduce the risk of relapse. Results also argue in favor of systematic screening for EF and theory of mind impairments among AUD patients.

A-32 Does Inhibition Contribute to Word Reading beyond Non-inhibition Processes?

Objective The current study aims to extend the study conducted by Van der Sluis and colleagues (2012) and investigate whether the statistical relationships between executive functioning (EF) and reading performance is causal or merely correlational. Methods A sample of children ages 5 to 12 years (N = 44) were given a standardized test of inhibition and its corresponding non-inhibition condition from the NEPSY-II assessment battery (Korkman, Kirk & Kemp, 2007) and the Letter-Word Identification test from the Woodcock Johnson IV Achievement Test Battery was given to assess reading (Schrank et al., 2014). Two separate hierarchical regressions were conducted to determine if inhibition predicted reading performance beyond that of its non-inhibition condition. Results The first regression examined the contribution of inhibition on reading after first accounting for the non-inhibition condition, and the second regression examined the contribution of the non-inhibition condition after first accounting for inhibition. Results indicate that inhibitory ability showed no significant contribution to prediction after controlling for the non-inhibition processes, and when first controlling for inhibitory ability, the non-executive processes from the non-inhibition condition continued to significantly contribute to word reading performance (ΔR2 = 0.21, F(1,44) = 25.11, p &lt; 0.01). Conclusions The results of the current study provide further support that relationship between EF and reading performance may be more of a statistical and procedural confound than it is a mechanism directly implicated in reading ability attainment. More work should be done to determine if the findings from this study are replicable across different tests of reading (i.e., comprehension, fluency).

ImGo: A Novel Tool for Behavioral Impulsivity Assessment Based on Go/NoGo Tasks

This manuscript aims to present a novel behavioral impulsivity test ImGo, which is suitable for impulsivity assessment in the general population. A series of three studies was conducted to validate its psychometric qualities. In Study 1 we describe the principles of ImGo and verify its test-retest and split-half reliability and its convergent validity with an impulsivity self-report scale and Stop Signal test. In Study 2 we re-analyze the convergent validity of ImGo with a Stop Signal test and examine the potential relationship between ImGo and oculomotor inhibition measured by an Anti-Saccades test. In Study 3 we present a robust research with a large sample size and investigate the discriminant validity of ImGo with tests of other related cognitive and executive processes. Backed by our findings from these studies we can safely claim ImGo is a powerful tool with a good level of reliability (both test-retest and split-half) and validity (convergent and discriminant). Its potential lies in its use in diagnostic and research practice of experts from various countries as the test has already been translated to 9 languages so far. The open-source Hypothesis platform, on which the ImGo test is running, provides the option of both individual and group testing in laboratory conditions as well as remotely through an internet browser.

In Search of the Executive Cognitive Processes Proposed by Process-Overlap Theory

Process-Overlap Theory (POT) suggests that measures of cognitive abilities sample from sets of independent cognitive processes. These cognitive processes can be separated into domain-general executive processes, sampled by the majority of cognitive ability measures, and domain-specific processes, sampled only by measures within a certain domain. According to POT, fluid intelligence measures are related because different tests sample similar domain-general executive cognitive processes to some extent. Re-analyzing data from a study by De Simoni and von Bastian (2018), we assessed domain-general variance from executive processing tasks measuring inhibition, shifting, and efficiency of removal from working memory, as well as examined their relation to a domain-general factor extracted from fluid intelligence measures. The results showed that domain-general factors reflecting general processing speed were moderately and negatively correlated with the domain-general fluid intelligence factor (r = −.17–−.36). However, domain-general factors isolating variance specific to inhibition, shifting, and removal showed only small and inconsistent correlations with the domain-general fluid intelligence factor (r = .02–−.22). These findings suggest that (1) executive processing tasks sample only few domain-general executive processes also sampled by fluid intelligence measures, as well as (2) that domain-general speed of processing contributes more strongly to individual differences in fluid intelligence than do domain-general executive processes.

Executive Processes and Emotional and Behavioural Problems in Youths Under Protective Measures

This research studies the executive processes of youths under protective measures between 13 and 18years of age, as well as the emotional problems they have and the presence of behavioural problems, such as difficulties to control and direct attention, to control one’s own behaviour and inhibit inadequate or ineffective responses (hyperactivity-impulsiveness) and problems related to emotional regulation. In addition, we study the presence of significant differences according to the sex of the youths. We also analyse to what extent the difficulties in the executive processes are related to and can predict the emotional and behavioural problems. The instruments used were Stroop’s Colour and Word Test (Stroop), the Paths Test (TESen), and the System of Evaluation for Children and Adolescents (SENA). The results indicated that the youths had difficulties in such executive processes as execution, speed, and accuracy in carrying out tasks. Furthermore, they had emotion problems, amongst which the symptoms of anxiety are worthy of note; whilst attention deficit, hyperactivity-impulsiveness, and problems related to emotional regulation could also be observed. The data indicated greater difficulties in the executive processes for males than for females. There was a greater emotional symptomatology in the females, whilst there were greater deficits in attention and hyperactivity/impulsiveness in the males. Similarly, the deficits in the executive processes were related to and predicted emotional and behavioural problems. This research suggests the design of a structured programme focused on systematic training in real, daily situations, recommending the use of restorative techniques to work on the affected cognitive skills and techniques aimed at improving the youths’ emotion regulation.