Engaging Students Through Integrated Pedagogy

This case study presents a model of integrated pedagogy in a two-semester college-level General Chemistry course. The model was designed to engage students safely during the first year of the COVID-19 pandemic. The authors use the term “Integrated Pedagogy” to emphasize that several modes of active learning pedagogy. The technology incorporated into the course was not as an add-on enhancement but as an essential and central element. The laboratory component was integrated into the course as an independent, self-directed experience. Informal student surveys suggest that the model may transform the traditional approaches to chemistry education to meet the changing needs of diverse student populations.

Practical approaches to examination of women with abnormal vaginal discharge: a review of evidence-based recommendations 2021

Abnormal vaginal discharge (AVD) is a syndrome that combines conditions of different origin (microbial/non-microbial) and of different anatomical localization (limited to vagina and exocervix/spreading from the endocervix to the pelvic organs) that cause discomfort and changes in the characteristics of vaginal discharge.Review objective: to systematize modern approaches to the diagnosis of the most common causes of AVD – bacterial vaginosis (BV), trichomoniasis, aerobic vaginitis (AV), vulvovaginal candidiasis (VVC) – in a practical context. Laboratory component of diagnosing the AVD causes should be complex due to the not fully understood mechanisms of regulation of vaginal biocenosis and changes in the virulence of opportunistic and pathogenic flora, leading to an increase in the frequency of mixed forms of vaginosis and their atypical course. The tasks of laboratory tests in AVD are determination of the sexually transmitted infections (gonorrhea, chlamydia, Mycoplasma genitalium) more often as a concomitant asymptomatic infection in combination with BV or another cause of AVD; confirmation of the suspected cause of AVD (BV, trichomoniasis, AV, VVC); differential diagnosis with more rare microbial causes (cytolytic vaginosis) and non-microbial causes.Vaginal pH and microscopy of vaginal discharge with an assessment according to the diagnostic criteria for dysbiosis are first line of available diagnostic tests of BV, AV and VVC. They make it possible to differentiate typical AVD causes from non-microbial AVD causes and rare causes of microbial AVD. Additionally, complex modern molecular methods for assessing the vaginal biocenosis can be used. Cultural methods play an important role in the diagnosis and treatment of recurrent/complicated VVC and AV. PCR for chlamydia, gonorrhea, trichomoniasis and Mycoplasma genitalium is a mandatory component of a comprehensive test in patients with suspected BV, AV or mixed dysbiosis. Patients diagnosed with BV or trichomoniasis has to be tested for HIV and sexually transmitted infections.

Digital Twin Based Interactive Mechatronics Lab Development for Remote Lab Offering and Evaluation

Mechatronics and control education is supported by laboratory intensive assignments that allow students acquire software and hardware skills to solve real world problems. However, COVID-19 force many schools to switch into remote learning complicating the instruction of practical assignments. This paper presents a novel proposal for interactive remote teaching of the laboratory component of the course ME-142: Mechatronics at the University of California, Merced using Digital Twins (DT) and the flipped classroom methodology. Each lab experience is composed by a set of on-demand supporting materials with the foundations of mechatronics simulation using MATLAB/Simulink to enhance and adapt the learning experience of the students. Once the students acquire advanced simulation skills, a set of Digital Twin models are provided to the students in order to begin their interaction with virtual representations of real systems for identification, analysis, controller design and validation, which are available online for remote access. By the end of the course, students were able not only to gain valuable experience with mechatronic systems but also interact and build advanced modelling techniques as Digital Twin, contributing to compensate the lack of remote hardware interaction.

Fighting COVID-19: The Medical Laboratory Involvement

The coronavirus disease-19 (COVID-19) virus has infected many people across the globe. The health system particularly medical laboratory has been overwhelmed by the pandemic, and many health professionals including medical laboratory professionals have lost their lives during the fight against the virus. Medical laboratory science is the bedrock of medical practice and the role of medical laboratory science in containing the COVID-19 pandemic cannot be overemphasized as they are also behind the testing of clinical specimens from infected and any recovered patients. As disease detectives, Medical laboratory scientists and other medical laboratory professionals’ role in the fight against the COVID-19 pandemic include; diagnosis, monitoring, development of vaccines, testing protocols, testing kits, offering advice to the guide government policy on containment of the virus.: Various methods and techniques such as virological cell culture, genomic sequencing, amplification, polymerase chain reaction (PCR) /gene Xpert systems, immunological testing, biosensors and rapid diagnostic techniques (RDTs) have been employed towards discovery, testing and epidemiology since the onset of COVID-19. The medical laboratory workers and other health workers are so visible at the COVID-19 frontline and are being recognized and applauded for the role played in the recovery of patients affected with the virus. The medical laboratory component is very germane in the COVID-19 vaccine research and vaccination so as to provide pre- and post-vaccination laboratory data.

A Data Warehouse Design for Dangerous Pathogen Monitoring

Emerging diseases are a major public health problem as illustrated by the current coronavirus disease (COVID-19) pandemic. To make the right decisions, public health departments need a decision-making system. In Africa few IT systems have been put in place to help managers of public health in the analysis of their multidisciplinary data. The majority of digital health solutions are operational databases, as well, focused on surveillance activities that do not include the laboratory component. This paper describes the design model and implementation of data warehouse for dangerous pathogen monitoring in a laboratories network. Talend data integration is used to extract data in Excel sheets, transform it and load it into a MySQL database.

Project-Based Learning and Evaluation in an Online Digital Design Course

This paper reports an experience of an abrupt shift from traditional teaching to distance learning within a course on digital system design using programmable logic platforms. The course organization and evaluation model had to be modified on the fly due to the COVID-19 pandemic. The adopted teaching and assessment methodology puts a strong focus on the laboratory component, assigning a very significant weight to project-based evaluation. As the access to laboratory equipment was cut, all the previously accumulated experience had to be modified and adapted to new circumstances. The paper discusses teaching methods employed within the course and analyzes in detail a project-based evaluation accentuated on modeling of a simplified processor. The advantages and drawbacks of the reported teaching methods are appointed. Possible design extensions are also suggested, which permit assigning the same core project to different students. We believe that the proposed project is a valuable instructional tool, in particular, for remote learning/assessment.

Artificial Light at Night Alters the Physiology and Behavior of Western Mosquitofish (Gambusia affinis)

Human population growth and its associated effects on the environment contribute to the rapid decrease of biodiversity worldwide. Artificial light at night (ALAN) is an anthropogenic pollutant that is increasing with the spread of urbanization and may contribute to biodiversity declines. ALAN alters the migration patterns of birds, communication in frogs, and impacts reproduction, behavior, and physiology of multiple other taxa. However, most of the studies on ALAN are based on terrestrial systems, and overall, the effects of ALAN on freshwater organisms are poorly understood. We investigated how ALAN affects the physiology, behavior, and reproduction of a widespread, tolerant species of freshwater fish. Gambusia affinis are small livebearing fish often found in urban streams. We exposed groups of female G. affinis to either a natural light cycle or a constant 24-h light cycle (ALAN) in the laboratory for 60 days. In another experiment, we exposed female G. affinis to the same treatments in outdoor mesocosms for 32 days. We found that exposure to ALAN lowered glucose levels in the brain and decreased swimming activity, but had no effect on cortisol release rates, reproduction, survival, or growth. This research is strengthened by measuring multiple metrics in response to ALAN and by incorporating both a field and laboratory component which confirm similar results. These results suggest that this tolerant species of fish may behaviorally adjust to ALAN rather than modulate their endocrine stress response.