Correlation between Electrophysiological Change and Facial Function in Parotid Surgery Patients

This observational study investigated intraoperative electrophysiological changes and their correlation with postoperative facial expressions in parotidectomy patients with visual confirmation of facial nerve (FN) continuity. Maximal electromyography(EMG) amplitudes of the facial muscles corresponding to temporal, zygomatic, buccal and mandibular branches were compared before/after FN dissection, and facial function at four facial regions were evaluated before/after parotidectomy in 112 patients. Comparisons of 448 pairs of EMG signals revealed at least one signal decrease after FN dissection in 75 (67%) patients. Regional facial weakness was only found in 13 of 16 signals with >50% amplitude decreases. All facial dysfunctions completely recovered within 6 months. EMG amplitude decreases often occur after FN dissection. An amplitude decrease >50% in an FN branch is associated with a high incidence of dysfunction in the corresponding facial region. This study tries to establish a standard facial nerve monitoring (FNM) procedure and a proper facial function grading system for parotid surgery that will be useful for the future study of FNM in parotid surgery.

Preoperative nTMS and Intraoperative Neurophysiology - A Comparative Analysis in Patients With Motor-Eloquent Glioma

BackgroundThe resection of a motor-eloquent glioma should be guided by intraoperative neurophysiological monitoring (IOM) but its interpretation is often difficult and may (unnecessarily) lead to subtotal resection. Navigated transcranial magnetic stimulation (nTMS) combined with diffusion-tensor-imaging (DTI) is able to stratify patients with motor-eloquent lesion preoperatively into high- and low-risk cases with respect to a new motor deficit.ObjectiveTo analyze to what extent preoperative nTMS motor risk stratification can improve the interpretation of IOM phenomena.MethodsIn this monocentric observational study, nTMS motor mapping with DTI fiber tracking of the corticospinal tract was performed before IOM-guided surgery for motor-eloquent gliomas in a prospectively collected cohort from January 2017 to October 2020. Descriptive analyses were performed considering nTMS data (motor cortex infiltration, resting motor threshold (RMT), motor evoked potential (MEP) amplitude, latency) and IOM data (transcranial MEP monitoring, intensity of monopolar subcortical stimulation (SCS), somatosensory evoked potentials) to examine the association with the postoperative motor outcome (assessed at day of discharge and at 3 months).ResultsThirty-seven (56.1%) of 66 patients (27 female) with a median age of 48 years had tumors located in the right hemisphere, with glioblastoma being the most common diagnosis with 39 cases (59.1%). Three patients (4.9%) had a new motor deficit that recovered partially within 3 months and 6 patients had a persistent deterioration (9.8%). The more risk factors of the nTMS risk stratification model (motor cortex infiltration, tumor-tract distance (TTD) ≤8mm, RMTratio <90%/>110%) were detected, the higher was the risk for developing a new postoperative motor deficit, whereas no patient with a TTD >8mm deteriorated. Irreversible MEP amplitude decrease >50% was associated with worse motor outcome in all patients, while a MEP amplitude decrease ≤50% or lower SCS intensities ≤4mA were particularly correlated with a postoperative worsened motor status in nTMS-stratified high-risk cases. No patient had postoperative deterioration of motor function (except one with partial recovery) when intraoperative MEPs remained stable or showed only reversible alterations.ConclusionsThe preoperative nTMS-based risk assessment can help to interpret ambiguous IOM phenomena (such as irreversible MEP amplitude decrease ≤50%) and adjustment of SCS stimulation intensity.

A new model for stress analysis in pin–Plate interference fit joints under tension loading

The decrease of stress amplitude is generally believed as the mechanism of fatigue life enhancement in interference fit joints under cyclic loading for each load cycle. In order to exactly estimate it, a new analytical model was presented. In this model, influences of mass, geometry, and plastic deformation are considered to modify and improve the spring model, and, moreover, the stress amplitude at the smallest crossing section is investigated. Taking these factors into account, stress amplitude decrease of various interference values can be calculated more accurately; therefore, the analytical solutions have good agreement with the finite element numerical and experimental results under different interference values and load levels. The analytical model indicates that the decrease ratio of stress amplitude is of a certain value for a specific interference value with the external load under the critical value. Furthermore, the decrease ratio of stress amplitude mainly depends on the stiffness of the pin and plate, which is mostly affected by the geometric shapes and plastic deformation ranges of the pin and plate. In addition, raising the interference value leads to larger stress amplitude reduction since the plastic deformation areas expand with the increment of interference values.

Spherical One-Way Wave Equation

The coordinate-free one-way wave equation is transferred in spherical coordinates. Therefore it is necessary to achieve consistency between gradient, divergence and Laplace operators and to establish, beside the conventional radial Nabla operator ∂Φ/∂r, a new variant ∂rΦ/r∂r. The two Nabla operator variants differ in the near field term Φ/r whereas in the far field r≫0 there is asymptotic approximation. Surprisingly, the more complicated gradient ∂rΦ/r∂r results in unexpected simplifications for – and only for – spherical waves with the 1/r amplitude decrease. Thus the calculation always remains elementary without the wattless imaginary near fields, and the spherical Bessel functions are obsolete.

Variations in Wave Energy and Amplitudes Along the Ray Paths of Barotropic Rossby Waves in Horizontally Non-Uniform Basic Flows

A non-divergent barotropic model on a sphere transformed to Mercator coordinates is used to examine the variations in wave energy and amplitude along the energy dispersion paths of barotropic Rossby waves in non-uniform basic flows. Wave energy can be easily solved by specifying the divergence of the group velocity along the corresponding rays. In an analytical non-uniform basic flow that represents the basic features of the observed one at middle latitudes, waves with different periods decay accompanying the decreases in wave energy and amplitude and the increase in the total wavenumber. This implies that the waves are trapped and the energy is eventually absorbed by the basic flow. For the observed non-uniform basic flow that can represent the basic features of the non-divergent wind field at 200 hPa, the situation is more complicated. The significant increase in wave energy can be caused by either the convergence of wave energy or the barotropic energy absorption from the basic flow or both of them. A significant increase in amplitude can also be observed if the total wavenumber varies moderately. This means waves can significantly develop. Waves may decay if both wave energy and amplitude decrease. Waves may propagate without significant developing or decaying to realize a long distance propagation. The propagating waves are mainly caused by oscillating wave energy as well as amplitude.

Tensile strength analysis of automatic periodic stimulation for continuous intraoperative neural monitoring in a piglet model

Continuous intraoperative neural monitoring (C-IONM) during thyroid surgery is a useful tool for preventing recurrent laryngeal nerve (RLN) injury. The present study aims to analyze the tensile strength tolerance of C-IONM electrodes on the vagal nerve (VN). A C-IONM wire was enclosed in a hand-held tensile testing system. The probe displacement on the VN was continuously monitored by positioning a second probe far-up/proximally in a piglet model, and an automatic periodic stimulation (APS) accessory was used. The 3-mm and 2-mm APS accessory has a mean tensile strength of 20.6 ± 10 N (range, 14.6–24.4 N) and 11.25 ± 8 N (range, 8.4–15.6 N), respectively (P = 0.002). There was no difference between bilateral VNs. The mean amplitude before and during electrode displacement was 1.835 ± 102 μV and 1.795 ± 169 μV, respectively (P = 0.45). The mean percentage of amplitude decrease on the electromyography (EMG) was 6.9 ± 2.5%, and the mean percentage of latency increase was 1.9 ± 1.5%. No significant amplitude reduction or loss of signal (LOS) was observed after > 50 probe dislocations. C-IONM probe dislocation does not cause any LOS or significant EMG alterations on the VN.

ENHANCING STRUCTURAL RESPONSE USING INERTER DAMPERS

This paper deals with one kind of dampers which is inerter damper, Inerter is a new mechanical element proposed by Professor Malcolm C. Smith from Cambridge University, which is defined as a mechanical two-terminal, one-port device with the property that the equal and opposite force applied at the terminals is proportional to the relative acceleration between the terminals the principle work of inerter damper is how to convert the linear motion into rotational motion to mitigation the external excitation. Theoretical analysis was presented first part is the analytical study which made modeling for the damping structure proposed and get the equation of motion for the inerter behavior, secondly numerical analysis where the program (ANSYS WORK-Bench 18.2) was adopted, and study the parameters which effected on the damping behavior of inerter structure proposed that is (stiffness, coefficient of friction and mass of flywheel). Where it was found that when the stiffness of the springs increased gradually from (0.2, 0.3, 0.4, 0.6 and 0.8) Kn/mm the amplitude reduced from (25.791, 17.194, 12.896, 8.5974 to 6.4482) mm respectively for each stiffness reading, also the mass of inerter when increased gradually (200,400,600,800 and 1000) g with a constant coefficient of friction and constant stiffness 0.4, 0.6 Kn/mm respectively, the amplitude decrease from 6.3525 to 4.036290. Finally, to study the effect inerter mass on the structures, the mass of inerter increased from (200,400,600,800 to 1000) g gradually to the constant cantilever mass structure equal to 130g. The ratio of the inerter mass to the threshold mass is approximately 1.5 to 7.5 As results obtained from the previous study, the amplitude obtained for each mass (1.0778, 1.069, 1.0509, 0.9514 to 0.872) respectively

Simultaneous Intra- and Extracochlear Electrocochleography During Cochlear Implantation to Enhance Response Interpretation

The use of electrocochleography (ECochG) for providing real-time feedback of cochlear function during cochlear implantation is receiving increased attention for preventing cochlear trauma and preserving residual hearing. Although various studies investigated the relationship between intra-operative ECochG measurements and surgical outcomes in recent years, the limited interpretability of ECochG response changes leads to conflicting study results and prevents the adoption of this method for clinical use. Specifically, the movement of the recording electrode with respect to the different signal generators in intracochlear recordings makes the interpretation of signal changes with respect to cochlear trauma difficult. Here, we demonstrate that comparison of ECochG signals recorded simultaneously from intracochlear locations and from a fixed extracochlear location can potentially allow a differentiation between traumatic and atraumatic signal changes in intracochlear recordings. We measured ECochG responses to 500 Hz tone bursts with alternating starting phases during cochlear implant insertions in six human cochlear implant recipients. Our results show that an amplitude decrease with associated near 180° phase shift and harmonic distortions in the intracochlear difference curve during the first half of insertion was not accompanied by a decrease in the extracochlear difference curve’s amplitude ( n = 1), while late amplitude decreases in intracochlear difference curves (near full insertion, n = 2) did correspond to extracochlear amplitude decreases. These findings suggest a role for phase shifts, harmonic distortions, and recording location in interpreting intracochlear ECochG responses.

Symmetry Modulates the Amplitude Spectrum Slope Effect on Visual Preference

Within the spectrum of a natural image, the amplitude of modulation decreases with spatial frequency. The speed of such an amplitude decrease, or the amplitude spectrum slope, of an image affects the perceived aesthetic value. Additionally, a human observer would consider a symmetric image more appealing than they would an asymmetric one. We investigated how these two factors jointly affect aesthetic preferences by manipulating both the amplitude spectrum slope and the symmetric level of images to assess their effects on aesthetic preference on a 6-point Likert scale. Our results showed that the preference ratings increased with the symmetry level but had an inverted U-shaped relation to amplitude spectrum slope. In addition, a strong interaction existed between symmetry level and amplitude spectrum slope on preference rating, in that symmetry can amplify the amplitude spectrum slope’s effects. A quadratic function of the spectrum slope can describe such effects. That is, preference is an inverted U-shaped function of spectrum slope whose intercept is determined by the number of symmetry axes. The modulation depth of the quadratic function manifests the interaction between the two factors.

Analysis of the Thermoelastic Damping Effect in Electrostatically Actuated MEMS Resonators

An important aspect that must be considered when designing micro-electro-mechanical systems (MEMS) for all domains, including robotics, is the thermoelastic damping which occurs when the MEMS material is subjected to cyclic stress. This paper is focused on a model for the thermoelastic damping developed based on the generalized thermoelastic theory with the non-Fourier thermal conduction equation. The model was implemented in MATLAB and several simulations were performed. The theoretical results show a decrease in the deflection amplitude with the increase in time. The deflection amplitude decrease was validated by the experimental investigations, consisting of measuring the loss in amplitude and velocity of oscillations as a function of time. Moreover, this paper also presents the influence of the geometric dimensions on the mentioned decrease, as well as on the initial and final values of the amplitude for several polysilicon resonators investigated in this paper.