Abstract
This article analyzes the impact of large-scale mass activities and extreme weather on the outbreak of COVID-19 in Wuhan, confirming that the South China Seafood Market is indeed the origin of the Wuhan epidemic, and found that the probability of respiratory transmission is low in open space, while food transmission is possible. At the same time, it was found that the outbreaks of SARS in Beijing in 2003 and COVID-19 in Wuhan in 2019 were both related to extreme weather. By investigating genomics and epidemiological data, it was determined that the first COVID-19 case in Wuhan was in November, and the beginning of the epidemic was in late November. Comparing the climate of November, December and January in Wuhan from 2011 to 2020, it is found that there are a lot of extreme weather events in Wuhan from the end of 2019 to the beginning of 2020, including strong winds, heavy rains, large cooling after continuous high temperature, and continuous low temperature and rainy after large cooling, the temperature suddenly rises and then drops rapidly, the wind continues to weaken for many days and then suddenly increases, and long rainy days, etc.