For corn grain traded in the country's forage production sector over the past two decades, enzyme immunoassay showed persistent contamination with toxins of fusarium fungi, more often T-2 / HT-2 toxins, fumonisins, and more rarely with deoxynivalenol and zearalenone in quantities that pose risks of animal intoxication. The cases of superintensive accumulation of cyclopiazonic acid, citrinin, mycophenolic acid and ochratoxin A. were revealed. In 2016-2018 For maize grain from 4 subjects of the Central Federal District of the Russian Federation, a significant prevalence of T-2 / HT-2 toxins, deoxynivalenol and fumonisins was found with fluctuations in the frequency of occurrence of zearalenone over the years, diacetoxyscirpenol was detected in several samples from the Kursk and Voronezh regions. Contamination of grain with alternariol in 2016 and 2017 was mild both in frequency (5.3%) and accumulation levels (20–85 µg / kg), but in the collection of 2018, the proportion of samples containing this toxin was 40.7% with a content range of 25 295 µg / kg. The influence of soil and climatic factors on the nature of mycotoxin contamination of corn grain crops, the contribution of fungi belonging to dark-colored hyphomycetes and the prevailing variants of combined contamination with fusariotoxins are discussed.