Colonization of the Respiratory Tract and Postoperative Pulmonary Infections

1973 ◽  
Vol 107 (2) ◽  
pp. 313 ◽  
Author(s):  
James D. Schlenker
2000 ◽  
Vol 38 (7) ◽  
pp. 2766-2767 ◽  
Author(s):  
Jann-Yuan Wang ◽  
Po-Ren Hsueh ◽  
Jann-Tay Wang ◽  
Li-Na Lee ◽  
Pan-Chyr Yang ◽  
...  

A 39-year-old woman with cystic bronchiectasis had repeated pulmonary infections from 1996 to 1999, and 6 of a total of 28 isolates of Escherichia coli from sputum specimens were studied. Their identical antibiotype and randomly amplified polymorphic DNA patterns indicated a single clone of E. coli, which persistently colonized the respiratory tract, causing recurrent infections.


Author(s):  
Cedric W. Lefebvre ◽  
Jay P. Babich ◽  
James H. Grendell ◽  
James H. Grendell ◽  
John E. Heffner ◽  
...  

PEDIATRICS ◽  
1961 ◽  
Vol 28 (3) ◽  
pp. 394-398
Author(s):  
Wilson Weisel ◽  
Derward Lepley

Case histories of three patients are reported, in whom adenomas of the respiratory tract produced dangerous prolonged morbidity in children before correct diagnosis was made. In all children with ususual wheezing disorders or recurrent pulmonary infections, the possible diagnosis of adenoma should be entertained. The proper treatment of adenomas of the respiratory tract in children is surgical excision of the tumor and of the permanently damaged lung tissue. Early diagnosis will reduce the incidence of pulmonary destruction and the possibility of metastasis.


1987 ◽  
Vol 33 (10) ◽  
pp. 888-895 ◽  
Author(s):  
Itzhak Brook

The presence of β-lactamase producing bacteria (βLPB) was investigated in specimens obtained from 1469 children who presented with infections of the skin and soft tissue (648), upper respiratory tract (514), pulmonary sites (137), surgical sites (113), and other (57). Of 4989 bacterial isolates recovered, 910 (18%) were βLPB, 492 (54%) aerobes, and 418 (46%) anaerobes. The βLPB were recovered in 751 (51%) of the children. The most frequently recovered βLPB was Staphylococcus aureus, which was recovered in 356 (47%) patients. Most isolates were recovered from patients with skin and soft-tissue infections (68% of patients), upper respiratory tract infections (49%), and pulmonary infections (35%). Bacteroides fragilis group was isolated in 35% of patients with βLPB, mostly from surgical infections (98% of patients), pulmonary infections (36%), skin and soft-tissue infections (25%), and upper respiratory tract infections (20%). Twenty-five percent of the Bacteroides melaninogenicus group produced β-lactamase. These organisms were recovered in 15% of patients with βLPB. They were recovered in upper respiratory tract infections (38% of patients), pulmonary infections (22%), and skin and soft-tissue infections (7%). Other βLPB were Pseudomonas aeruginosa (8% of total patients with βLPB), Escherichia coli (4%), Bacteroides oralis (3%), Klebsiella pneumoniae (3%), Haemophilus influenzae (2%), Proteus (1%), and Branhamella catarrhalis (1%). The role of βLPB in the failure of penicillin to eradicate many of the infections is discussed.


2021 ◽  
Vol 12 ◽  
Author(s):  
Andreina Bruno ◽  
Giuliana Ferrante ◽  
Serena Di Vincenzo ◽  
Elisabetta Pace ◽  
Stefania La Grutta

Leptin is a pleiotropic adipocytokine involved in several physiologic functions, with a known role in innate and adaptive immunity as well as in tissue homeostasis. Long- and short-isoforms of leptin receptors are widely expressed in many peripheral tissues and organs, such as the respiratory tract. Similar to leptin, microbiota affects the immune system and may interfere with lung health through the bidirectional crosstalk called the “gut-lung axis.” Obesity leads to impaired protective immunity and altered susceptibility to pulmonary infections, as those by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although it is known that leptin and microbiota link metabolism and lung health, their role within the SARS-CoV2 coronavirus disease 2019 (COVID-19) deserves further investigations. This review aimed to summarize the available evidence about: (i) the role of leptin in immune modulation; (ii) the role of gut microbiota within the gut-lung axis in modulating leptin sensitivity; and (iii) the role of leptin in the pathophysiology of COVID-19.


2014 ◽  
Vol 189 (11) ◽  
pp. 1309-1315 ◽  
Author(s):  
Katrine L. Whiteson ◽  
Barbara Bailey ◽  
Megan Bergkessel ◽  
Douglas Conrad ◽  
Laurence Delhaes ◽  
...  

2015 ◽  
Vol 64 (2) ◽  
pp. 150-153
Author(s):  
Mihaela Ciornei ◽  
◽  
Elena Hanganu ◽  
Diana Ecaterina Popa ◽  
T. Stanciu ◽  
...  

Eventration of the diaphragm, congenital or acquired, represents a rare condition (1 to 10,000 live births), in which the dome of the diaphragm is abnormally elevated, due to an excessive amount of fi bro-elastic diaphragmatic tissue. The child may be asymptomatic or present with respiratory symptoms as aggressive as life threatening respiratory distress. Recurrent pulmonary infections are the commonest presenting complaints. We present the case of a 3 years old boy with recurrent chest infections and apparent “dextrocardia”, both caused by a left eventration of the diaphragm, successfully treated by plication.


Author(s):  
Shahida Akhtar ◽  
Asifa Nazir ◽  
Humaira Bashir

Background: Respiratory tract infection are an important cause of mortality and morbidity worldwide. The prevalent bacterial agents and their antimicrobial resistance patterns differs, both geographically and over time. Bronchoalveolar lavage has improved sensitivity and specificity of diagnostic techniques in diagnosis of pulmonary infections. The present study aimed to determine the current aerobic bacterial isolates and their sensitivity pattern obtained from the bronchoalveolar lavage (BAL) fluid of patients with pulmonary infection.Methods: BAL samples received from the patients of suspected respiratory tract infections over a period of one year, from June 2018 to May 2019 were processed by standard methods for isolation and identification. The antimicrobial susceptibility was done by the Kirby-Bauer disc diffusion method as per the CLSI guidelines.Results: Out of 322 BAL samples, 84 (26.08%) were found to be culture positive for bacterial isolates. Of those, 44 samples (52.38%) from among males and 40 samples (47.61%) from among females were culture positive .The predominant organism isolated was Pseudomonas aeruginosa 46 (54.76%) followed by Acinetobacter baumanii 13 (15.47%), Escherichia coli 10 (11.90%), Klebsiella pnuemoniae 6 (7.14%) Enterobacter sp 3 (3.57%), Staphylococcus aureus 3 (3.57%), Enterococcus sp 2 (2.38%) and Sphingomonas sp 1 (1.19%). The Gram-negative organisms showed maximum sensitivity to colistin (100%) while as vancomycin and linezolid were the most effective drugs against Gram positive organisms.Conclusions: Bronchoalveolar lavage has improved sensitivity and specificity in diagnosis of pulmonary infections. It is important to have an updated local antibiogram for each hospital and regular surveillance and monitoring of antibiotic resistance and the changing patterns of the bacterial pathogens is a must for better patient management.


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