TRACHEAL AND BRONCHIAL ADENOMAS IN CHILDHOOD

PEDIATRICS ◽  
1961 ◽  
Vol 28 (3) ◽  
pp. 394-398
Author(s):  
Wilson Weisel ◽  
Derward Lepley
Keyword(s):  
Early Diagnosis ◽  
Respiratory Tract ◽  
Lung Tissue ◽  
Correct Diagnosis ◽  
Surgical Excision ◽  
Proper Treatment ◽  
Pulmonary Infections ◽  
Case Histories ◽  
Made In

Case histories of three patients are reported, in whom adenomas of the respiratory tract produced dangerous prolonged morbidity in children before correct diagnosis was made. In all children with ususual wheezing disorders or recurrent pulmonary infections, the possible diagnosis of adenoma should be entertained. The proper treatment of adenomas of the respiratory tract in children is surgical excision of the tumor and of the permanently damaged lung tissue. Early diagnosis will reduce the incidence of pulmonary destruction and the possibility of metastasis.

scholarly journals Prospective selected biomarkers in COVID-19 diagnosis and treatment

2021 ◽  
Author(s):  
Tahani Tabassum ◽  
Ahsab Rahman ◽  
Yusha Araf ◽  
Md A Ullah ◽  
Mohammad J Hosen
Keyword(s):  
Early Diagnosis ◽  
Risk Groups ◽  
Viral Pathogenesis ◽  
Health Concern ◽  
Effective Strategy ◽  
Proper Treatment ◽  
Pulmonary Infections ◽  
Disease Prognosis ◽  
Proper Diagnosis

COVID-19 has become a global health concern, due to the high transmissible nature of its causal agent and lack of proper treatment. Early diagnosis and nonspecific medical supports of the patients appeared to be effective strategy so far to combat the pandemic caused by COVID-19 outbreak. Biomarkers can play pivotal roles in timely and proper diagnosis of COVID-19 patients, as well as for distinguishing them from other pulmonary infections. Besides, biomarkers can help in reducing the rate of mortality and evaluating viral pathogenesis with disease prognosis. This article intends to provide a broader overview of the roles and uses of different biomarkers in the early diagnosis of COVID-19, as well as in the classification of COVID-19 patients into multiple risk groups.

ANALYSIS OF PLANT FRAGARIA XANANASSA DISEASE DIAGNOSES USING PRODUCTION RULES BASE ON EXPERT SYSTEM

2020 ◽  
Vol 16 (1) ◽  
pp. 25-32
Author(s):  
Basiroh Basiroh ◽  
Wiji Lestari
Keyword(s):  
Expert System ◽  
Early Diagnosis ◽  
General Public ◽  
Insect Pests ◽  
Fruit Rot ◽  
Proper Treatment ◽  
Harvest Time ◽  
Production Rules

Errors that occur in solving problems in strawberry plants (Fragaria Xananassa) such as the presence of leaf patches, fruit rot, perforated leaves, and insect pests can be the cause of not maximum in harvest time. The farmers and the general public who planted strawberry (Fragaria Xananassa) need to know the proper treatment of diseases and pests so that future yields as expected. Therefore, it takes an application as a solution in the delivery of information related to the problems that are often encountered in strawberry plants (Fragaria Xananassa). Methods of production rules can be used to diagnose the disease strawberry (Fragaria Xananassa) based on signs or symptoms that occur in the parts of plants and strawberry, the results of diagnosis using this method are the same as we do Consultation on experts.  The purpose of this study was to determine the early diagnosis of disease in strawberry plants (Fragaria Xananassa) based on signs or symptoms that occur in the plant and fruit parts. The results of the analysis of this study showed that the validation of disease and symptom data in strawberry plants (Fragaria Xananassa) reached 99%, meaning that between the data of symptoms and disease understudy the accuracy was guaranteed with the experts.

Hernia interna estrangulada por plastrón en el tercio distal del apéndice cecal

2019 ◽  
Vol 62 (6) ◽  
pp. 24-27
Author(s):  
Leslie M. Leyva Sotelo ◽  
José E. Telich Tarriba ◽  
Daniel Ángeles Gaspar ◽  
Osvaldo I. Guevara Valmaña ◽  
André Víctor Baldín ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Small Bowel ◽  
Early Diagnosis ◽  
Intestinal Obstruction ◽  
Acute Abdomen ◽  
Internal Hernia ◽  
Wide Spectrum ◽  
Internal Hernias ◽  
Mild Abdominal Pain ◽  
Made In

Internal hernias are an infrequent cause of intestinal obstruction with an incidence of 0.2-0.9%, therefore their early diagnosis represents a challenge. The most frequently herniated organ is the small bowel, which results in a wide spectrum of symptoms, varying from mild abdominal pain to acute abdomen. We present the case of an eight-year old patient with nonspecific digestive symptoms, a transoperative diagnosis was made in which an internal hernia was found strangulated by plastron in the distal third of the appendix. Appendectomy was performed and four days later the patient was discharged without complications.

A High Prevalence of Affective Disorder Discovered in a ‘Schizophrenia Clinic’

1977 ◽  
Vol 22 (4) ◽  
pp. 181-183 ◽  
Author(s):  
Morton S. Rapp ◽  
Peggy Edwards
Keyword(s):  
Affective Disorder ◽  
Affective Disorders ◽  
Correct Diagnosis ◽  
Lithium Carbonate ◽  
Case Histories ◽  
Clinical Notes ◽  
The Past ◽  
High Prevalence ◽  
Incorrect Diagnosis

Fifty outpatients in a ‘schizophrenia clinic’ were examined, and sixteen were found to be suffering from periodic affective disorders. Nine of these were given lithium carbonate, and eight responded well. Case histories illustrate three separate reasons for incorrect diagnosis. Examination of extensive old clinical notes of five of these patients suggests that the problems of diagnosis which have been described in the literature in the past, continue to represent obstacles to correct diagnosis. Suggestions for improvement are offered.

scholarly journals Evolution of Diploid Progenitor Lung Cell Applications: From Optimized Biotechnological Substrates to Potential Active Pharmaceutical Ingredients in Respiratory Tract Regenerative Medicine

Cells ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2526
Author(s):  
Alexis Laurent ◽  
Philippe Abdel-Sayed ◽  
Nathalie Hirt-Burri ◽  
Corinne Scaletta ◽  
Murielle Michetti ◽  
...  
Keyword(s):  
Regenerative Medicine ◽  
Respiratory Tract ◽  
Lung Tissue ◽  
Cell Types ◽  
Active Pharmaceutical Ingredients ◽  
Vaccine Production ◽  
Diploid Progenitor ◽  
Pharmaceutical Ingredients ◽  
The 1960S ◽  
Pharmacopoeial Requirements

The objective of this review is to describe the evolution of lung tissue-derived diploid progenitor cell applications, ranging from historical biotechnological substrate functions for vaccine production and testing to current investigations around potential therapeutic use in respiratory tract regenerative medicine. Such cell types (e.g., MRC-5 or WI-38 sources) were extensively studied since the 1960s and have been continuously used over five decades as safe and sustainable industrial vaccine substrates. Recent research and development efforts around diploid progenitor lung cells (e.g., FE002-Lu or Walvax-2 sources) consist in qualification for potential use as optimal and renewed vaccine production substrates and, alternatively, for potential therapeutic applications in respiratory tract regenerative medicine. Potentially effective, safe, and sustainable cell therapy approaches for the management of inflammatory lung diseases or affections and related symptoms (e.g., COVID-19 patients and burn patient severe inhalation syndrome) using local homologous allogeneic cell-based or cell-derived product administrations are considered. Overall, lung tissue-derived progenitor cells isolated and produced under good manufacturing practices (GMP) may be used with high versatility. They can either act as key industrial platforms optimally conforming to specific pharmacopoeial requirements or as active pharmaceutical ingredients (API) for potentially effective promotion of lung tissue repair or regeneration.

scholarly journals The role of membrane-destabilizing processes in the pathogenesis and clinical manifestations of perinatal encephalopathy in children

2001 ◽  
Vol 82 (2) ◽  
pp. 137-138
Author(s):  
E. V. Levitina ◽  
G. A. Ivanichev ◽  
M. M. Minnibaev
Keyword(s):  
Nervous System ◽  
Early Diagnosis ◽  
Clinical Manifestations ◽  
Perinatal Period ◽  
Diagnosis And Treatment ◽  
Definition Of ◽  
Methods Of Treatment ◽  
All Diseases ◽  
Made In

2/3 of all diseases of the nervous system in children begin to develop in the perinatal period. In recent decades, great strides have been made in perinatal neurology in the development of criteria for early diagnosis and treatment of diseases. Further study of the biochemical foundations of perinatal lesions of the nervous system with the definition of objective markers of the severity of the lesion will reveal new links in its pathogenesis and develop more effective methods of treatment.

Diphtheria: the patch remains

2003 ◽  
Vol 117 (10) ◽  
pp. 807-810 ◽  
Author(s):  
Raj Nandi ◽  
Mriganka De ◽  
Simon Browning ◽  
Prabhati Purkayastha ◽  
A. K. Bhattacharjee
Keyword(s):  
Early Diagnosis ◽  
Respiratory Tract ◽  
Respiratory Distress ◽  
Retrospective Analysis ◽  
Fatal Disease ◽  
Disease Characteristics ◽  
Intravenous Antibiotics ◽  
Number Of Patients ◽  
History Of ◽  
Clinical Records

This study analysed the number of patients admitted with diphtheria to a teaching hospital in the state of Assam in India over a period of five years and compared the disease characteristics and management with outcomes and incidences of diphtheria reported in the literature. It was a retrospective analysis of data elicited from clinical records of patients admitted to hospital.A total of 101 admissions were recorded during a five-year period between March 1997 to March 2002, mostly with pharyngeal diphtheria (90 per cent). The majority of patients had no history of immunization (70 per cent). Significant presenting features were a tonsillar patch, sore throat, respiratory distress and fever. All patients were treated with anti-diphtheritic serum and intravenous antibiotics. Steroids were given to 81 per cent of patients and tracheostomy was carried out in 10 per cent of cases. The mortality was 16 per cent.Diphtheria of the respiratory tract remains a potentially fatal disease commonly presenting with membranous pharyngitis. Early diagnosis and treatment with anti-diphtheritic serum and antibiotics remain the cornerstone of treatment. Inadequate immunization cover is deemed responsible for the continued menace of diphtheria.

Myofibroma of the Gingiva: Report of a Case

2010 ◽  
Vol 34 (3) ◽  
pp. 253-257 ◽  
Author(s):  
Banu Özveri Koyuncu ◽  
Mert Zeytinoğlu ◽  
Taha Ünal ◽  
Bülent Zeytinoğlu
Keyword(s):  
Benign Tumor ◽  
Smooth Muscle Actin ◽  
Correct Diagnosis ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Solitary Lesion ◽  
Immunohistochemical Markers ◽  
Mesenchymal Neoplasm ◽  
S 100 ◽  
Histopathologic Evaluation

Myofibroma is a benign mesenchymal neoplasm composed of myofibroblasts which has been described with different synonyms since the first report in 1951. It occurs most commonly as a solitary lesion of soft tissue,skin, or bone in infancy. The prognosis of oral myofibromas is excellent, and surgical excision is curative. Recurrence is rare. Awareness and recognition of this benign tumor is important to establish the correct diagnosis and avoid morbidity of unnecessary aggressive therapy. This report describes a myofibroma of the gingiva in a 14 year old girl and is reported together with the conventional histologic, and immunohistochemical findings. The tumor showed rapid increase in size and clinical features suggestive of malignancy. However, on histopathologic evaluation it was diagnosed as a benign neoplasm, and this diagnosis was supported by immunohistochemical markers. The spindle cells were immunopositive for smooth muscle actin,and vimentin but were negative for desmin and S-100 protein. The patient was treated with surgical excision,and is followed-up for 33 months without any signs of recurrence.

Unusual presentation of granular cell tumour of buccal mucosa

2021 ◽  
Vol 14 (9) ◽  
pp. e242242
Author(s):  
Zhi Yon Charles Toh ◽  
Thomas Cooper ◽  
Maryam Jessri ◽  
Frank S-C Chang
Keyword(s):  
Buccal Mucosa ◽  
Correct Diagnosis ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Complete Surgical Excision ◽  
Uncommon Presentation ◽  
Long Term Follow Up

Granular cell tumour (GCT) is a rare soft tissue lesion which many consider to have malignant potential of yet unknown aetiopathogenesis. Oral GCT lesions may occur in an area of leucoplakia and are predominantly present on the tongue. This case study highlights an uncommon presentation of this condition located on the buccal mucosa and illustrates the need for meticulous evaluation of suspicious lesions. Due to the malignant risk associated with GCT lesions, it is important to make the correct diagnosis and ensure complete surgical excision for these cases. Ongoing long-term follow-up is also indicated to monitor for recurrence or malignancy.

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