Placental growth patterns affect birth weight for given placental weight

2007 ◽  
Vol 79 (4) ◽  
pp. 281-288 ◽  
Author(s):  
Carolyn M. Salafia ◽  
Jun Zhang ◽  
Richard K. Miller ◽  
Adrian K. Charles ◽  
Patrick Shrout ◽  
...  
Keyword(s):  
Birth Weight ◽  
Growth Patterns ◽  
Placental Weight

Does Placental Weight Affects Perinatal Outcome? A Prospective Case-control Study

2020 ◽  
Vol 16 (1) ◽  
pp. 52-59
Author(s):  
Naina Kumar ◽  
Himani Agarwal
Keyword(s):  
Birth Weight ◽  
High Risk ◽  
Perinatal Outcome ◽  
Case Control Study ◽  
Neonatal Outcome ◽  
Case Control ◽  
Placental Weight ◽  
Tertiary Center ◽  
Control Study ◽  
Prospective Case Control Study

Background: Placenta plays a very important role in the growth and development of fetus. Objective: To know the correlation between placental weight and perinatal outcome in term antenatal women. Methods: Present prospective case-control study was conducted in the rural tertiary center of Northern India over one year (January-December 2018) on 1,118 term (≥37-≤42 weeks) antenatal women with singleton pregnancy fulfilling inclusion criteria with 559 women with high-risk pregnancy as cases and 559 low-risk pregnant women as controls. Placental weight, birth weight was measured immediately after delivery and compared between the two groups along with gestation, parity, fetal gender, and neonatal outcome. Statistical analysis was done using SPSS 22 version. Results: Mean placental weight [481.98±67.83 gm vs. 499.47±59.59 gm (p=.000)] and birth weight [2.68±0.53 Kg vs. 2.88±0.4 Kg (p=.000)] was significantly lower in high risk as compared to lowrisk participants, whereas placental birth weight ratio was higher in high-risk cases [18.35±2.37 vs. 17.41±1.38 (p=.000)] respectively. Placental weight was positively correlated with birth weight and placental weight and birth weight increased with increasing gestation in both cases and controls. Male neonates had higher placental weight [492.74±68.24 gm vs. 488±58.8 gm (p=0.224)] and birth weight [2.81±0.5 Kg vs. 2.74±0.45 Kg (p=0.033)] as compared to females. Neonatal Intensive Care Unit admission was significantly associated with low placental and birth weight (p=.000). Conclusion: There is a significant correlation between placental weight, birth weight and neonatal outcome, hence placental weight can be used as an indirect indicator of intrauterine fetal growth.

Placental plasticity in monochorionic twins: Impact on birth weight and placental weight

Placenta ◽  
2015 ◽  
Vol 36 (9) ◽  
pp. 1018-1023 ◽  
Author(s):  
Marc U. Baumann ◽  
Michelle Marti ◽  
Lukas Durrer ◽  
Petros Koumoutsakos ◽  
Panagiotis Angelikopoulos ◽  
...  
Keyword(s):  
Birth Weight ◽  
Placental Weight ◽  
Monochorionic Twins

scholarly journals Relationship between Birth Weight, Placental Weight and Apgar score in Dosso, Niger Republic

2021 ◽  
Vol 38 ◽  
pp. 27-37
Author(s):  
Jussara Ennes ◽  
Muryllo Santos ◽  
Ana Beatriz Torres ◽  
Samille Avila
Keyword(s):  
Birth Weight ◽  
Apgar Score ◽  
Placental Weight

Comparative assessment of Placental Weight and Fetal Outcome in Normal and Anaemic Mothers during Intranatal Period in Selected Hospitals in India

2021 ◽  
pp. 72-80
Author(s):  
. Lalhriatpuii ◽  
Bali Thool
Keyword(s):  
Birth Weight ◽  
Negative Impact ◽  
Good Condition ◽  
Sampling Technique ◽  
Fetal Outcome ◽  
Placental Weight ◽  
Descriptive Research ◽  
Significant Difference ◽  
Average Condition ◽  
Significant Health

Background: Despite the fact that anaemia during pregnancy is the most prevalent and significant health problem in impoverished nations, anaemia has a negative impact on the placenta and fetal development. The placenta is a growing organ that provides nutrition, oxygen, and eliminates excretory wastes for the fetus while also acting as a protective barrier throughout pregnancy. If the placenta is compromised by anaemia, it has a negative impact on the foetus's growth. Methods and Materials: Comparative descriptive research design was used, 60 subjects (30 normal mothers and 30 anaemic mothers) were allotted and in this study the purposive sampling technique was used to select the sample. The aim of the study was to compare the placental weight and fetal outcome in normal mothers and anaemic mothers. The objectives of the study were (i) To assess the placental weight in normal mothers and anaemic mothers. (ii)To assess the fetal outcome in normal mothers and anaemic mothers. (iii)To compare the placental weight and fetal outcome in normal and anaemic mothers. Results: The result of the study shows that 93% normal mothers had average condition of placental weight, 2% normal mothers had good condition of placental weight while in anaemic mothers it was found that 30 percent had average condition of placental weight, 73.3% normal mothers had average condition of fetal outcome, 26.7% normal mothers had good condition of fetal outcome while in anaemic mothers it was found that 93.3% percent had average condition of fetal outcome, 06.7% had good condition of fetal outcome. Conclusion: The study concludes that the comparison between placental weight and birth weight of babies shows significant difference with a positive relationship in both the groups. This means as the placental weight increases the birth weight also increases and vice-versa.

The effect of litter size, age of ewe and Booroola gene (Fee B) on the birth and placental characteristics of Texel ewes

1997 ◽  
Vol 1997 ◽  
pp. 179-179
Author(s):  
Jennifer M.L. Anderson ◽  
J.S. Boyd ◽  
M.J. Harvey ◽  
A. Waterhouse
Keyword(s):  
Birth Weight ◽  
Litter Size ◽  
Placental Weight

It is widely recorded that placental weight varies a great deal in uniformly treated ewes, yet this variation remains unexplained (Mellor, 1983). The aim of this experiment was to assess the effects of differing parameters on birth weight, placental weight, and number and weight of cotyledons in Texel ewes carrying the Booroola fecundity gene.

P–406 Placental histopathology is different in specific subsets of ICSI singleton pregnancies with programmed cycles : a prospective study

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
M Varma ◽  
S Singh ◽  
R Tangri ◽  
H Tuli ◽  
R Kumar ◽  
...  
Keyword(s):  
Birth Weight ◽  
Embryo Transfer ◽  
Placental Weight ◽  
Inflammatory Lesions ◽  
Amsterdam Criteria ◽  
Number Of Patients ◽  
Increased Risk ◽  
Tertiary Center ◽  
P 16 ◽  
Singleton Pregnancies

Abstract Study question Does embryo vitrification or donor oocytes (DO) alter the histopathology of the placenta in ICSI singleton pregnancies with similar endometrial preparation? Summary answer Placentas from programmed cycles had significantly more immune/idiopathic-inflammation with vitrified-thawed embryos versus fresh transfer and significantly more maternal vascular-malperfusion(MVM) in DO versus autologous oocyte(AO) pregnancies. What is known already DO pregnancies and frozen embryo transfer(FET) pregnancies with programmed cycles are associated with hypertensive complications. As these complications are linked with abnormal placentation, comparing the placental histopathology in these pregnancies may point to a causative association. Studies of placental histopathology in DO in comparison to AO pregnancies show a dysregulated immune process and vasculopathy. The hormonal milieu during implantation remains an important confounder. Placental histopathology in fresh/ frozen cycles has recently shown variable results. To isolate the effect of embryo vitrification on placental histopathology, the donor oocyte model can provide valuable data, which till now is scarcely available. Study design, size, duration A prospective cohort study conducted in a tertiary center from 2018–2020. Placental histopathology, pregnancy-outcomes were studied in 116 ICSI singleton pregnancies≥28 weeks. Group1-Pregnancies with DO, by FET(n = 32) and freshET(n = 34) were compared to study the effect of embryo-vitrification. Group2-Pregnancies by DO FET(n = 32) were compared to AO FET(n = 50) to study the effect of DO. All patients had ICSI, cleavage embryo-transfer, programmed cycles and delivered at the same institute. The placentas were examined by pathologists (blinded to the ET type). Participants/materials, setting, methods 116 singleton pregnancies were followed for hypertensive disorders of pregnancy (HDP), preterm delivery(PTD<37weeks) and low birth-weight (LBW<2.5kg). Placentas were examined for cord mal-insertions Placental histopathology lesions were classified into 4 groups according to ‘Amsterdam criteria’ infectious-inflammatory, immune/ idiopathic-inflammatory, MVM, fetal vascular malperfusion (FVM). Chi-square and t-tests were used to compare outcomes across groups. Adjusted odds ratio were calculated using logistic regression. Statistical significance set at P <.05, two-tailed. Main results and the role of chance No patient had a history of chronic hypertension/smoking. Group 1 Patients conceived by DO, with FET and freshET were comparable with regards to age (34.1 vs 36.4years, P=.07),BMI(26.7 vs 27.1 kg/m2,P=.6),nulliparity(81%vs82%,P=.9) HDP(25%vs29.4%,P=0.69),birth-weight(2.48 vs 2.47kg,P=.93) LBW(31.3%vs41.2%,P=.41)respectively PTD was significantly less in donor FET versus donor freshET (6.3%vs47.1%P=.0002) Placental weight and cord mal-insertions were comparable for FET vs freshET (466 vs 486gms P=.03 12.5%vs23.5% P=.25)respectively. Amongst the placental histopathology lesions, immune/ idiopathic-inflammatory lesions were significantly more in the FET vs freshET group (37.5% vs 11.8%,P=.02)The other lesions were comparable infectious-inflammatory(6.3%vs17.6%,P=.16), MVM(75%vs58.8%, P=.16),FVM(18.8%vs17.6%,P=.9) Group 2 Patients conceived by DO compared to AO by FET were significantly older and had a higher BMI (34.1vs31.7years,P=.02 ,26.7vs25.5 kg/m2,P=.002) respectively. Nulliparity was comparable(81%vs92%,P=.15) Birth weight was significantly less in DO vs AO(2.4vs2.7kg,P=.02) HDP and LBW were significantly more in DO vs AO(25%vs8% ,P=.03, 31.3%vs 8%,P=.007),respectively. PTD was comparable(6.3%vs8.0%,P=.77). Placental weight was significantly less in DO vs AO (466 vs 513gms,P=.03) cord mal-insertions were comparable(12.5% vs 24%,P=.2) The MVM lesions were significantly more in the DO group compared to AO(75% vs 40%,P=.002) The difference remained after adjusting for age/BMI/HDP (AOR 4.31;95% CI 1.24–14.8;P=.02). The rest of placental lesions were comparable in DO vs AO, infectious-inflammatory lesions(6.3%vs16%,P=.19) immune/idiopathic-inflammatory lesions(37.5%vs28%,P=.37) FVM(18.8% vs 12%,P=.4)respectively. Limitations, reasons for caution These findings are based on a small number of patients. The results observed need to be confirmed using a larger study sample. Wider implications of the findings: Placentas in pregnancies by embryo-vitrification, in a DO-model, had significantly more immune/idiopathic-inflammation, the cause/significance of this needs to be explored. Placentas in DO-pregnancies had significantly more MVM-lesions and increased risk of HDP, emphasizing the clinical/histopathological link of DO with HDP and the need for counselling/preventive strategies for HDP in DO-pregnancie. Trial registration number Not applicable

Mean Placental Birth Weight Ratio at Term in Primigravidae

2021 ◽  
Vol 15 (11) ◽  
pp. 3496-3498
Author(s):  
Nazia Muneer ◽  
Shamaila Shamaun ◽  
Afshan Shahid ◽  
Riffat Jaleel ◽  
Mehreen Iqbal ◽  
...  
Keyword(s):  
Birth Weight ◽  
Maternal Age ◽  
Weight Ratio ◽  
Operational Definition ◽  
Cross Sectional Study ◽  
Placental Weight ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
The Mean

Objective: To determine the mean placental birth weight ratio at term in primigravidae Study design: Cross-sectional study Place and Duration: Department of Obstetrics and Gynecology, Civil Hospital Karachi, duration was six months after the approval of synopsis from 1st January 2016 to 30th June 2016 Subjects and Methods: A total of pregnant women who fulfill the inclusion criteria were included in this study. After delivery, baby was weighed by using weight machine and weight of baby was also noted (as per operational definition). After expulsion of complete placenta, placental weight was measured by using weight machine. The placental-birth weight ratio (PBWR) were calculated as ratio of placental weight to neonatal weight multiplied by 100. Results: Mean ± SD of maternal age was 24.77±4.04 with C.I (24.11----25.42) years. Mean ± SD of placental weight was 505.84±99.97 with C.I (489.71----521.97) grams. Out of 150 neonatal babies 101 (67.3%) were male and 49 (32.7%) were female. Mean placental birth weight ratio was found to be 16.82±2.63 with C.I (16.39----17.24). Conclusion: It is to be concluded that placental weight increased according to the birth weight. The placental weight to birth weight ratio decreased slightly with advancing gestational age. Keywords: Placental weight, Birth weight ratio, Labour at term, Primigravidae

scholarly journals Maternal Supplementation with Polyphenols and Omega-3 Fatty Acids during Pregnancy: Effects on Growth, Metabolism, and Body Composition of the Offspring

Animals ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1946
Author(s):  
Ana Heras-Molina ◽  
José Luis Pesantez-Pacheco ◽  
Susana Astiz ◽  
Consolación Garcia-Contreras ◽  
Marta Vazquez-Gomez ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Linseed Oil ◽  
Growth Patterns ◽  
Daily Weight Gain ◽  
Control Group ◽  
Practical Recommendation ◽  
Metabolic Traits ◽  
Maternal Supplementation

Maternal supplementation with antioxidants and n3 PUFAs may be a promising strategy to reduce the risk of intrauterine growth restriction and preterm delivery, which may diminish the appearance of low-birth-weight neonates. The present study aimed to determine benefits and risks of a dietary supplementation combining hydroxytyrosol, a polyphenol from olive leaves and fruits, and n3 PUFAs, from linseed oil, on developmental patterns and metabolic traits of offspring in swine, a model of IUGR pregnancies. The results obtained indicate that maternal supplementation with hydroxytyrosol and n-3 fatty acids during pregnancy has no deleterious effects on the reproductive traits of the sows (prolificacy, homogeneity of the litter, and percentage of stillborns and low-birth-weight, LBW, piglets) and the postnatal features of the piglets (growth patterns, adiposity, and metabolic traits). Conversely, in spite of a lower mean weight and corpulence at birth, piglets from the supplemented sows showed higher average daily weight gain and fractional growth rate. Thus, at juvenile stages afterwards, the offspring from the treated group reached higher weight and corpulence, with increased muscle development and better lipidemic and fatty acid profiles, in spite of similar adiposity, than offspring in the control group. However, much caution and more research are still needed before practical recommendation and use in human pregnancies.

scholarly journals Maternal Hematological Parameters and Placental and Umbilical Cord Histopathology in Intrauterine Growth Restriction

2019 ◽  
Vol 28 (2) ◽  
pp. 101-108 ◽  
Author(s):  
Mária Jakó ◽  
Andrea Surányi ◽  
László Kaizer ◽  
Gábor Németh ◽  
György Bártfai
Keyword(s):  
Platelet Count ◽  
Birth Weight ◽  
Umbilical Cord ◽  
Intrauterine Growth Restriction ◽  
Hematological Parameters ◽  
Placental Weight ◽  
Sectional Area ◽  
Cross Sectional ◽  
Intrauterine Growth ◽  
Placental Volume

Objective: To investigate the placental and umbilical cord histopathology in intrauterine growth restriction (IUGR) and their relation to second-trimester maternal hematological parameters. Materials and Methods: Patients were selected for the IUGR group based on estimated fetal weight below the 10th percentile. Patients were recruited into the control group randomly. Patients were followed up with ultrasound, and blood samples were taken between the 20th and 24th gestational weeks. After delivery and formalin fixation, weight and volume of the placenta were recorded and histologic samples were processed. Results: Maternal platelet count strongly correlates with placental weight (r = 0.766). On the other hand, neonatal weight correlates with placental volume (r = 0.572) rather than with placental weight (r = 0.469). Umbilical arterial lumen cross-sectional area correlates with birth weight (r = 0.338). Conclusions: Maternal hematological parameters do not seem to affect neonatal outcome. Our main findings are the correlation of maternal platelet count with placental weight, the correlation of placental volume with birth weight being stronger than the correlation of placental weight with birth weight, and the correlation of umbilical artery lumen cross-sectional area with neonatal weight. Mild histopathologic alterations might occur in normal pregnancies; however, sufficient fetal nutrition can be maintained. This compensatory function of the placenta seems to be insufficient when two or more pathologies are present, which is characteristic for IUGR.

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