scholarly journals A review on recent developments in the biosynthesis of silver nanoparticles and its biomedical applications

2020 ◽  
Author(s):  
Rizwan Arif ◽  
Sapana Jadoun ◽  
Rahis Uddin

Water ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 2216
Author(s):  
Muhammad Zahoor ◽  
Nausheen Nazir ◽  
Muhammad Iftikhar ◽  
Sumaira Naz ◽  
Ivar Zekker ◽  
...  

Recent developments in nanoscience have appreciably modified how diseases are prevented, diagnosed, and treated. Metal nanoparticles, specifically silver nanoparticles (AgNPs), are widely used in bioscience. From time to time, various synthetic methods for the synthesis of AgNPs are reported, i.e., physical, chemical, and photochemical ones. However, among these, most are expensive and not eco-friendly. The physicochemical parameters such as temperature, use of a dispersing agent, surfactant, and others greatly influence the quality and quantity of the synthesized NPs and ultimately affect the material’s properties. Scientists worldwide are trying to synthesize NPs and are devising methods that are easy to apply, eco-friendly, and economical. Among such strategies is the biogenic method, where plants are used as the source of reducing and capping agents. In this review, we intend to debate different strategies of AgNP synthesis. Although, different preparation strategies are in use to synthesize AgNPs such as electron irradiation, optical device ablation, chemical reduction, organic procedures, and photochemical methods. However, biogenic processes are preferably used, as they are environment-friendly and economical. The review covers a comprehensive discussion on the biological activities of AgNPs, such as antimicrobial, anticancer anti-inflammatory, and anti-angiogenic potentials of AgNPs. The use of AgNPs in water treatment and disinfection has also been discussed in detail.



2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
Adnan Haider ◽  
Inn-Kyu Kang

Silver nanoparticles (Ag-NPs) have diverted the attention of the scientific community and industrialist itself due to their wide range of applications in industry for the preparation of consumer products and highly accepted application in biomedical fields (especially their efficacy against microbes, anti-inflammatory effects, and wound healing ability). The governing factor for their potent efficacy against microbes is considered to be the various mechanisms enabling it to prevent microbial proliferation and their infections. Furthermore a number of new techniques have been developed to synthesize Ag-NPs with controlled size and geometry. In this review, various synthetic routes adapted for the preparation of the Ag-NPs, the mechanisms involved in its antimicrobial activity, its importance/application in commercial as well as biomedical fields, and possible application in future have been discussed in detail.



Dose-Response ◽  
2021 ◽  
Vol 19 (2) ◽  
pp. 155932582110113
Author(s):  
Pamela Nair Silva-Holguín ◽  
Simón Yobanny Reyes-López

Researchers are currently looking for materials that are stable, functional, aesthetic, and biocompatible without infections. Therefore, there is a great interest in obtaining a material that has a balance between aesthetic, biological, mechanical, and functional factors, which can be used as an infection control material. The addition of hydroxyapatite to alumina make highly bioactive scaffolds with mechanical strength. Biomedical applications require antibacterial properties; therefore, this idea leads to great interest in the development of new synthetic routes of ceramic biomaterials that allow the release of nanoparticles or metal ions. This investigation presents the obtention of alumina-hydroxyapatite spheres doped with silver nanoparticles with antibacterial effect against various Gram-positive and negative bacteria related to drug-resistance infections. The microstructural and spectroscopic studies demonstrate that the spheres exhibit a homogeneous structure and crystal hydroxyapatite and silver nanoparticles are observed on the surface. The antimicrobial susceptibility was verified with the agar diffusion and turbidimetry methods in Gram-negative ( Escherichia coli and Pseudomonas aeruginosa) and Gram-positive ( Staphylococcus aureus and Bacillus subtilis) bacteria. All bacteria used were susceptible to the alumina-hydroxyapatite-silver spheres even at lower silver concentration. The composites have a higher possibility for medical applications focused on the control of drug-resistance microorganisms.



2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Oluyomi Stephen Adeyemi ◽  
Ifeoluwa Adewumi

Background. Silver nanoparticles have found wider and increasing biomedical applications due to their broad antimicrobial characteristics. However, toxicity of nanoparticles is a subject of continued controversy, thus necessitating further studies in this direction. Objectives. This study investigated the biochemical effects of silver nanoparticles in Wistar rats. Materials and Methods. Forty male rats were randomly distributed into eight experimental groups of five. Group A served as the control and received distilled water. Groups B to H were orally exposed to varying concentrations of silver nanoparticles (AgNPs) at 100, 1000, and 5000 mg/kg daily for 7, 14, and 21 days alternately. Following cessation of treatments, rats were sacrificed and the blood and other vital organs were collected and prepared as specimens for biochemical analysis. Results. Administration of AgNPs to rats did not produce significant loss in feed intake and body weight. However, rat exposure to AgNPs caused significant alterations to levels of serum and tissue AST, ALT, and ALP. At the 100 mg/kg AgNPs exposure, rat serum and tissue AST and ALT levels were significantly decreased (P < 0.05). In contrast, AgNPs administration elevated (P < 0.05) ALP levels in rat serum and tissues. Conclusion. We show evidence that AgNPs administration to Wistar rats altered some biochemical parameters.



2017 ◽  
Vol 130 ◽  
pp. 442-450 ◽  
Author(s):  
Facundo Mattea ◽  
José Vedelago ◽  
Francisco Malano ◽  
Cesar Gomez ◽  
Miriam C. Strumia ◽  
...  


2018 ◽  
Vol 38 (2) ◽  
pp. 49-76 ◽  
Author(s):  
Amna Kamal ◽  
Muhammad Adnan Iqbal ◽  
Haq Nawaz Bhatti

AbstractSelenium is a biocompatible element and participates in several biochemical reactions occurring in the human body. Its biocompatibility and minimal toxicity has attracted researchers to develop selenium-based drugs. Hence, recent developments on biomedical applications of selenium-based compounds have been discussed. A structure activity relationship has also been interpreted.



F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 2118 ◽  
Author(s):  
Anna J. Simon ◽  
Andrew D. Ellington

Synthetically engineered organisms hold promise for a broad range of medical, environmental, and industrial applications. Organisms can potentially be designed, for example, for the inexpensive and environmentally benign synthesis of pharmaceuticals and industrial chemicals, for the cleanup of environmental pollutants, and potentially even for biomedical applications such as the targeting of specific diseases or tissues. However, the use of synthetically engineered organisms comes with several reasonable safety concerns, one of which is that the organisms or their genes could escape their intended habitats and cause environmental disruption. Here we review key recent developments in this emerging field of synthetic biocontainment and discuss further developments that might be necessary for the widespread use of synthetic organisms. Specifically, we discuss the history and modern development of three strategies for the containment of synthetic microbes: addiction to an exogenously supplied ligand; self-killing outside of a designated environment; and self-destroying encoded DNA circuitry outside of a designated environment.



Nanomaterials ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 567
Author(s):  
Jin-Woo Oh ◽  
Dong-Wook Han

This Special Issue highlights the recent developments and future directions of virus-based nanomaterials and nanostructures in energy and biomedical applications. The virus-based biomimetic materials formulated using innovative ideas presented herein are characterized for the applications of biosensors and nanocarriers. The research contributions and trends based on virus-based materials, covering energy-harvesting devices to tissue regeneration over the last two decades, are described and discussed.





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