Copper as a Growth Promoter

Author(s):  
B. C. Cooke
Keyword(s):  
2019 ◽  
Vol 19 (4A) ◽  
pp. 167-174
Author(s):  
Do Huu Hoang

In the last three decades aquaculture is a rapidly developing sector worldwide and antibiotics are used popularly as growth promoter. Antibiotic use was banned because research proved that antibiotic has caused many effects on environment and human health. Therefore, finding antibiotic alternatives is the first priority. The most prospect products today are probiotic and prebiotic. β-glucan is one of the immunostimulants which showed a variety of benefits to the health of many aquaculture species. In this paper only the results of β-glucan, a kind of prebiotic supplied in aquaculture, were summarized. The major benefit of β-glucan are to boost growth, to reduce mortality, to enhance tolerance or stress resistance to environmental or pathogen challenges. Although the applications of β-glucan are popular worldwide, its use in aquaculture in Vietnam is still limited. This paper provides an important reference for β-glucan utilisation which may help to develop a sustainable aquaculture in Vietnam.


2019 ◽  
Vol 52 (3) ◽  
Author(s):  
Arooj Javed ◽  
Azhar Hussain Shah ◽  
Anwar Hussain ◽  
Zabta Khan Shinwari ◽  
Seema Ali Khan ◽  
...  

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 286-286
Author(s):  
Kwangwook Kim ◽  
Sungbong Jang ◽  
Yanhong Liu

Abstract Our previous studies have shown that supplementation of low-dose antibiotic growth promoter (AGP) exacerbated growth performance and systemic inflammation of weaned pigs infected with pathogenic Escherichia coli (E. coli). The objective of this experiment, which is extension of our previous report, was to investigate the effect of low-dose AGP on gene expression in ileal mucosa of weaned pigs experimentally infected with F18 E. coli. Thirty-four pigs (6.88 ± 1.03 kg BW) were individually housed in disease containment rooms and randomly allotted to one of three treatments (9 to 13 pigs/treatment). The three dietary treatments were control diet (control), and 2 additional diets supplemented with 0.5 or 50 mg/kg of AGP (carbadox), respectively. The experiment lasted 18 d [7 d before and 11 d after first inoculation (d 0)]. The F18 E. coli inoculum was orally provided to all pigs with the dose of 1010 cfu/3 mL for 3 consecutive days. Total RNA [4 to 6 pigs/treatment on d 5; 5 to 7 pigs/treatment on 11 post-inoculation (PI)] was extracted from ileal mucosa to analyze gene expression profiles by Batch-Tag-Seq. The modulated differential gene expression were defined by 1.5-fold difference and a cutoff of P < 0.05 using limma-voom package. All processed data were statistically analyzed and evaluated by PANTHER classification system to determine the biological process function of genes in these lists. Compared to control, supplementation of recommended-dose AGP down-regulated genes related to inflammatory responses on d 5 and 11 PI; whereas, feeding low-dose AGP up-regulated genes associated with negative regulation of metabolic process on d 5, but down-regulated the genes related to immune responses on d 11 PI. The present observations support adverse effects of low-dose AGP in our previous study, indicated by exacerbated the detrimental effects of E. coli infection on pigs’ growth rate, diarrhea and systemic inflammation.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Yung-Chang Lin ◽  
Sungwoo Lee ◽  
Yueh-Chiang Yang ◽  
Po-Wen Chiu ◽  
Gun-Do Lee ◽  
...  

AbstractInterhalogen compounds (IHCs) are extremely reactive molecules used for halogenation, catalyst, selective etchant, and surface modification. Most of the IHCs are unstable at room temperature especially for the iodine-monofluoride (IF) whose structure is still unknown. Here we demonstrate an unambiguous observation of two-dimensional (2D) IF bilayer grown on the surface of WSe2 by using scanning transmission electron microscopy and electron energy loss spectroscopy. The bilayer IF shows a clear hexagonal lattice and robust epitaxial relationship with the WSe2 substrate. Despite the IF is known to sublimate at −14 °C and has never found as a solid form in the ambient condition, but surprisingly it is found stabilized on a suitable substrate and the stabilized structure is supported by a density functional theory. This 2D form of IHC is actually a byproduct during a chemical vapor deposition growth of WSe2 in the presence of alkali metal halides as a growth promoter and requires immediate surface passivation to sustain. This work points out a great possibility to produce 2D structures that are unexpected to be crystallized or cannot be obtained by a simple exfoliation but can be grown only on a certain substrate.


Animals ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 48
Author(s):  
Maria Latif ◽  
Mehwish Faheem ◽  
Asmatullah ◽  
Seyed Hossein Hoseinifar ◽  
Hien Van Doan

This feeding trial was conducted to investigate the effects of dietary black seed (Nigella sativa) supplementation on the growth performance, muscles proximate composition, antioxidant and histo-biochemical parameters of rohu (Labeo rohita). Fingerlings (8.503 ± 0.009 g) were fed on 0.0%, 1% and 2.5% black seed supplemented diets for 28 days. Fish sampling was done on the 7th, 14th, 21st and 28th day of experiment. The results of the present study indicated that black seed supplementation significantly increased growth performance and muscles protein contents of rohu over un-supplemented ones. Lipid peroxidation levels significantly decreased in all the studied tissues (liver, gills, kidney and brain) of black seed fed rohu, whereas the antioxidant enzymes (catalase, glutathione-S-transferase, glutathione peroxidase and reduced glutathione) activities were increased in all the studied tissues of black seed supplemented rohu at each sampling day. The hepatic-nephric marker enzymes levels were decreased for black seed fed rohu. The present study showed that tested black seed levels are safe for rohu. Black seed is cheaply available in local markets of Pakistan; therefore, based on the results of the present study, it is suggested that black seed has potential to be used as natural growth promoter and antioxidant in the diet of rohu.


Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2266
Author(s):  
Markéta Prokešová ◽  
Milena Bušová ◽  
Mahyar Zare ◽  
Hung Quang Tran ◽  
Eliška Kučerová ◽  
...  

In the present study, a possible nature immunostimulant and growth promoter—humic substances (HS) originating from Siberian leonardite mineraloid—were tested on juvenile Clarias gariepinus performance. Feed additive was applied onto commercial pelleted feed at four HS levels—0, 1, 3, and 6% w/w (HS0, HS1, HS3, HS6, respectively). Diets were tested in five repetitions (in total, n = 1800 individuals, mean body weight 28.1 ± 6.2 g) for 56 days. Growth and production parameters, fish condition and somatic indices, and overall mortality were evaluated after 14, 28, 42, and 56 days of exposure. Whereas, plasma samples were collected only after 0, 28, and 56 days, when fish health status was assessed with biochemical parameters (total proteins, TP; alanine aminotransferase, ALT; aspartate aminotransferase, AST; lactate dehydrogenase, LDH; cholesterol, CHOL; triglycerides, TAG) and fish antioxidant status with glutathione (reduced glutathione, GSH; oxidized glutathione, GSSG; glutathione ratio GSH/GSSG). Although a significantly positive effect of HS feed additive on growth performance was not found in the present study, moderately positive effects were found regarding biochemical parameters (ALT, AST, LDH, CHOL, and TAG) and antioxidants (GSH/GSSG ratio) that were improved especially in the HS3 group.


2017 ◽  
Vol 3 (1) ◽  
pp. 103-108
Author(s):  
Md Sirazul Islam ◽  
M Mamnur Rashid ◽  
Mohammad Shamsul Arefin ◽  
Pronab Naha ◽  
Md Rokanuddula

A study was conducted to determine the efficacy of three most commonly used growth promoters from different pharmaceutical companies on growth performance of hybrid walking catfish (Clarias batrachus × Clarias gariepinus). The experiment was done in the wet laboratory of the Department of Aquaculture, BAU, Mymensingh, with a total of 10 aquaria and 160 fish having mean initial weight of 6.3 ± 0.48 g. The three growth promoters, “Charger gel” from Fishtech (BD) Ltd., “Growth gel” from Advance Agrotech (BD) Ltd. and “Hepaprotect-aqua” from Renata Animal health Ltd., were used in separate nine (9) aquaria at recommended, lower dose and higher dose respectively. One aquarium was used as control (diet without any growth promoter). The fish were fed with paragon nursery floating feed at 20% of body weight in each aquarium for 28 days. Doses of Charger gel were given as 80, 60 and 100 mg/20 g feed/day, that of Growth gel, 0.14, 0.12 and 0.16 ml/20 g feed/day and of Hepaprotect-aqua, 30, 15 and 50 mg/20 g feed/day. Re-circulatory system was used throughout the experimental period. By applying recommended, lower and higher dose of “Charger gel”, mean final weights were found as 23.0, 21.9 and 35.9 g; average daily weight gain as 0.60, 0.56 and 1.06 g and specific growth rate (SGR) as 2.01, 1.93 and 2.70% respectively. For “Growth gel”, mean final weights were found as 22.8, 17.3 and 31.1 g; average daily weight gain as 0.59, 0.39 and 0.88 g and SGR as 1.99, 1.57 and 2.48 % respectively. For “Hepaprotect-aqua”, mean final weights were found as 24.2, 17.5 and 28.2 g; average daily weight gain as 0.64, 0.40 and 0.78 g and SGR as 2.09, 1.58 and 2.32% respectively. In all the cases survival rates were 100%. All the three growth promoters showed better results at their higher doses in comparison to their results in lower and recommended doses. However, in average Charger gel showed the best result than the other two growth promoters. This information on the efficacy study of growth promoters needs to be disseminated to the farmers for improved fish production.Asian J. Med. Biol. Res. March 2017, 3(1): 103-108


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