Direct Immunoassays: Limitations on the Physical Principles and on the Technology State of the Art

1993 ◽  
pp. 433-441
Author(s):  
M. Alvarez-Icaza ◽  
A. Gebbert ◽  
R. D. Schmid
Keyword(s):  
State Of The Art ◽  
Physical Principles

Dynamics of Multiphase Flows

2021 ◽  
Author(s):  
Chao Zhu ◽  
Liang-Shih Fan ◽  
Zhao Yu
Keyword(s):  
Multiphase Flows ◽  
Engineering Students ◽  
State Of The Art ◽  
Computational Techniques ◽  
Lagrangian Trajectory ◽  
Real World Applications ◽  
Liquid Flows ◽  
Engineering Practices ◽  
Solid Liquid ◽  
Physical Principles

Understand multiphase flows using multidisciplinary knowledge in physical principles, modelling theories, and engineering practices. This essential text methodically introduces the important concepts, governing mechanisms, and state-of-the-art theories, using numerous real-world applications, examples, and problems. Covers all major types of multiphase flows, including gas-solid, gas-liquid (sprays or bubbling), liquid-solid, and gas-solid-liquid flows. Introduces the volume-time-averaged transport theorems and associated Lagrangian-trajectory modelling and Eulerian-Eulerian multi-fluid modelling. Explains typical computational techniques, measurement methods and four representative subjects of multiphase flow systems. Suitable as a reference for engineering students, researchers, and practitioners, this text explores and applies fundamental theories to the analysis of system performance using a case-based approach.

DOPED LEAD TELLURIDE-BASED SEMICONDUCTORS: NEW POSSIBILITIES FOR DETECTION OF TERAHERZ RADIATION

2004 ◽  
Vol 18 (16) ◽  
pp. 2223-2245 ◽  
Author(s):  
DMITRIY KHOKHLOV
Keyword(s):  
Wavelength Range ◽  
Focal Plane ◽  
State Of The Art ◽  
Lead Telluride ◽  
Photon Radiation ◽  
Submillimeter Wavelength ◽  
Group Iii ◽  
Physical Features ◽  
Fast Quenching ◽  
Physical Principles

Doping of the lead telluride and related alloys with the group III impurities results in the appearance of unique physical features of the material, such as persistent photoresponse, enhanced responsive quantum efficiency (up to 100 photoelectrons/incident photon), radiation hardness and many others. We review physical principles of operation of the photodetecting devices based on the group III doped IV–VI including possibilities of fast quenching of the persistent photoresponse, construction of a focal-plane array, new readout technique, and others. Comparison of performance of the state of the art Ge ( Ga ) and Si ( Sb ) photodetectors with their lead telluride based analogs shows that the responsivity of PbSnTe ( In ) photodetectors is by several orders of magnitude higher. High photoresponse is detected at the wavelength of 241 μm in PbSnTe ( In ), and it is possible that the photoconductivity spectrum covers all the submillimeter wavelength range.

Lead telluride-based far-infrared photodetectors – a promising alternative to doped Si and Ge

2001 ◽  
Vol 692 ◽  
Author(s):  
Dmitriy Dolzhenko ◽  
Ivan Ivanchik ◽  
Dmitriy Khokhlov
Keyword(s):  
State Of The Art ◽  
Lead Telluride ◽  
Far Infrared ◽  
Photon Radiation ◽  
Submillimeter Wavelength ◽  
Promising Alternative ◽  
Group Iii ◽  
Physical Features ◽  
Fast Quenching ◽  
Physical Principles

AbstractDoping of the lead telluride and related alloys with the group III impurities results in appearance of unique physical features of the material, such as persistent photoresponse, enhanced responsive quantum efficiency (up to 100 photoelectrons/incident photon), radiation hardness and many others. We review physical principles of operation of the photodetecting devices based on the group III-doped IV-VI including possibilities of fast quenching of the persistent photoresponse, construction of a focal-plane array, new readout technique, and others. Comparison of performance of the state of the art Ge(Ga) and Si(Sb) photodetectors with their lead telluride-based analogs shows that the responsivity of PbSnTe(In) photodetectors is by several orders of magnitude higher. High photoresponse is detected at the wavelength 116 micrometers in PbSnTe(In), and it is possible that the photoconductivity spectrum covers all the submillimeter wavelength range.

Intrinsically radiopaque biomaterial assortments: A short review on the physical principles, X-ray imageability and state-of-the-art developments.

2021 ◽  
Author(s):  
Sneha K. R. ◽  
G.S. Sailaja
Keyword(s):  
State Of The Art ◽  
Short Review ◽  
X Ray ◽  
Decisive Parameter ◽  
Physical Principles

X-ray attenuation ability, otherwise known as radiopacity of a material could be indisputably tagged as the central and decisive parameter that produces contrast in an X-ray image. Radiopaque biomaterials are...

X-Ray Analysis of Frozen Hydrated Sections:The Unconventional Approach

1982 ◽  
Vol 40 ◽  
pp. 754-757
Author(s):  
R. Beeuwkes ◽  
A. Saubermann ◽  
P. Echlin ◽  
S. Churchill
Keyword(s):  
Ratio Method ◽  
Frozen Sections ◽  
Technical Problems ◽  
Sample Handling ◽  
X Ray ◽  
Common Group ◽  
Ideal Method ◽  
Classic Paper ◽  
Physical Principles ◽  
The Ideal

Fifteen years ago, Hall described clearly the advantages of the thin section approach to biological x-ray microanalysis, and described clearly the ratio method for quantitive analysis in such preparations. In this now classic paper, he also made it clear that the ideal method of sample preparation would involve only freezing and sectioning at low temperature. Subsequently, Hall and his coworkers, as well as others, have applied themselves to the task of direct x-ray microanalysis of frozen sections. To achieve this goal, different methodological approachs have been developed as different groups sought solutions to a common group of technical problems. This report describes some of these problems and indicates the specific approaches and procedures developed by our group in order to overcome them. We acknowledge that the techniques evolved by our group are quite different from earlier approaches to cryomicrotomy and sample handling, hence the title of our paper. However, such departures from tradition have been based upon our attempt to apply basic physical principles to the processes involved. We feel we have demonstrated that such a break with tradition has valuable consequences.

Practical Picture Processing

1974 ◽  
Vol 32 ◽  
pp. 338-339
Author(s):  
T. A. Welton
Keyword(s):  
Radiation Damage ◽  
Coherence Length ◽  
Spatial Information ◽  
State Of The Art ◽  
Coherent Radiation ◽  
The State ◽  
Energy Spread ◽  
Electron Micrograph ◽  
Picture Processing ◽  
Molecular Skeleton

Various authors have emphasized the spatial information resident in an electron micrograph taken with adequately coherent radiation. In view of the completion of at least one such instrument, this opportunity is taken to summarize the state of the art of processing such micrographs. We use the usual symbols for the aberration coefficients, and supplement these with £ and 6 for the transverse coherence length and the fractional energy spread respectively. He also assume a weak, biologically interesting sample, with principal interest lying in the molecular skeleton remaining after obvious hydrogen loss and other radiation damage has occurred.

The Basic Physical Principles of Ion, Electron, and X-Ray Detectors and Their Application to Microanalysis

1985 ◽  
Vol 43 ◽  
pp. 154-157
Author(s):  
A.J. Tousimis
Keyword(s):  
Ion Beam ◽  
Depth Resolution ◽  
Sample Surface ◽  
High Energy ◽  
X Rays ◽  
X Ray ◽  
Electrons And Ions ◽  
Spatial Depth ◽  
Minimum Surface Area ◽  
Physical Principles

An integral and of prime importance of any microtopography and microanalysis instrument system is its electron, x-ray and ion detector(s). The resolution and sensitivity of the electron microscope (TEM, SEM, STEM) and microanalyzers (SIMS and electron probe x-ray microanalyzers) are closely related to those of the sensing and recording devices incorporated with them.Table I lists characteristic sensitivities, minimum surface area and depth analyzed by various methods. Smaller ion, electron and x-ray beam diameters than those listed, are possible with currently available electromagnetic or electrostatic columns. Therefore, improvements in sensitivity and spatial/depth resolution of microanalysis will follow that of the detectors. In most of these methods, the sample surface is subjected to a stationary, line or raster scanning photon, electron or ion beam. The resultant radiation: photons (low energy) or high energy (x-rays), electrons and ions are detected and analyzed.

A Macintosh Interface for the Cameca Camebax-Micro Electron Microprobe

1990 ◽  
Vol 48 (1) ◽  
pp. 438-439
Author(s):  
Carl E. Henderson
Keyword(s):  
Electron Microprobe ◽  
Processing Speed ◽  
Word Processing ◽  
State Of The Art ◽  
Computer Control ◽  
Third Party ◽  
Disk Storage ◽  
The Past ◽  
User Facility ◽  
Instrument Control

Over the past few years it has become apparent in our multi-user facility that the computer system and software supplied in 1985 with our CAMECA CAMEBAX-MICRO electron microprobe analyzer has the greatest potential for improvement and updating of any component of the instrument. While the standard CAMECA software running on a DEC PDP-11/23+ computer under the RSX-11M operating system can perform almost any task required of the instrument, the commands are not always intuitive and can be difficult to remember for the casual user (of which our laboratory has many). Given the widespread and growing use of other microcomputers (such as PC’s and Macintoshes) by users of the microprobe, the PDP has become the “oddball” and has also fallen behind the state-of-the-art in terms of processing speed and disk storage capabilities. Upgrade paths within products available from DEC are considered to be too expensive for the benefits received. After using a Macintosh for other tasks in the laboratory, such as instrument use and billing records, word processing, and graphics display, its unique and “friendly” user interface suggested an easier-to-use system for computer control of the electron microprobe automation. Specifically a Macintosh IIx was chosen for its capacity for third-party add-on cards used in instrument control.

Current Issues: Advanced Digital Technology for Supervising Graduate Clinicians

2010 ◽  
Vol 20 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Glenn Tellis ◽  
Lori Cimino ◽  
Jennifer Alberti
Keyword(s):  
Real Time ◽  
Digital Technology ◽  
Clinical Training ◽  
State Of The Art ◽  
Clinical Skills ◽  
Slow Motion ◽  
Video Capture ◽  
Microsoft Excel ◽  
Clinical Supervisors ◽  
Training And Supervision

Abstract The purpose of this article is to provide clinical supervisors with information pertaining to state-of-the-art clinic observation technology. We use a novel video-capture technology, the Landro Play Analyzer, to supervise clinical sessions as well as to train students to improve their clinical skills. We can observe four clinical sessions simultaneously from a central observation center. In addition, speech samples can be analyzed in real-time; saved on a CD, DVD, or flash/jump drive; viewed in slow motion; paused; and analyzed with Microsoft Excel. Procedures for applying the technology for clinical training and supervision will be discussed.

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