Dengue hemorrhagic fever: Clinical manifestations and management

1999 ◽  
Vol 66 (1) ◽  
pp. 93-101 ◽  
Author(s):  
S. K. Kabra ◽  
Y. Jain ◽  
T. Singhal ◽  
V. H. Ratageri
2018 ◽  
Vol 24 (8) ◽  
pp. 6221-6224
Author(s):  
Hindra Irawan Satari ◽  
Rossy Agus Mardani ◽  
Hartono Gunardi

Various clinical manifestations, complex pathogenesis and different virus serotypes in diverse area make us difficult to predict course of disease, even the child admitted in early. Prognostic factors are very important to predict cases progressing to become DSS. Dengue shock syndrome (DSS) occurs in 15.53% of Dengue hemorrhagic fever (DHF) patients with 7.81% mortality rate. Aim: To explore the prognostic factors of shock in hospitalized DHF children regarding the new 2011 WHO dengue virus infection classification guideline. This was a retrospective study using medical records of children age below 18 years old with WHO fulfilled grade 1 and 2 DHF diagnosis from January 2013–December 2016 in Child Health Department of Dr. Cipto Mangunkusumo Hospital, Jakarta. Independent variables were sex, age, nutritional status, secondary dengue infection, leucopenia, abdominal tenderness, gastrointestinal bleeding, hepatomegaly and plasma leakage. Shock was dependent variable. Multivariate analysis was done by using logistic regresion analysis. There were 98 DHF subjects, 5 subjects became DSS during hospitalization. DSS subject characteristics were age of >5 years old, female, malnutrition, abdominal tenderness, hemoconcentration ≥20%, secondary dengue infection, leucocyte ≥5.000 mm3 and thrombocyte <50.000 mm3. Multivaryate analysis showed malnutrition and hepatomegaly were prognosis factors of DSS. Malnutrition and hepatomegaly were prognotic factors of dengue shock syndrome. Clinicians should be more aware with these factors when managed hospitalized DHF patients.


e-CliniC ◽  
2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Ribka Wowor

Abstract: In Indonesia, dengue hemorrhagic fever (DHF) is a serious health problem. Infection of dengue has occurred in Indonesia for the last two decades. It is a self limiting disease, however, its clinical manifestations has become worsened since several years ago. Epidemiologic pattern of dengue infection changes every year, and there is a peak of new cases every 10 years. Nowadays, adolescence and adult individuals belong to the high risk population of this infection. This epidemiologic changing of DHF is influenced by several environmental factors, inter alia: 1) increasing of human population; 2) uncontrolled urbanization; 3) no effective control of mosquitoes in endemic areas; and 4) modernized public transportation.Keywords: environmental sanitation, epidemiology, dengue hemorrhagic fever Abstrak: Di Indonesia, demam berdarah dengue (DBD) masih merupakan masalah kesehatan masyarakat yang penting. Infeksi dengue terjadi secara endemis di Indonesia selama dua abad terakhir. Penyakit ini bersifat self limiting namun dalam beberapa tahun terakhir memperlihatkan manifestasi klinis yang semakin berat sebagai DBD dan frekuensi kejadian luar biasanya semakin meningkat. Pola epidemiologi infeksi dengue mengalami perubahan dari tahun ke tahun, jumlah kasus memuncak setiap siklus 10 tahunan. Kelompok usia yang terserang dengue berubah menjadi kelompok remaja dan dewasa. Perubahan epidemiologi DBD ini turut dipengaruhi oleh faktor kesehatan lingkungan. Faktor-faktor yang memengaruhi peningkatan dan penyebaran kasus DBD sangat kompleks yaitu, antara lain: 1) pertumbuhan penduduk yang tinggi dan cepat; 2) urbanisasi yang tidak terencana dan tidak terkendali; 3) tidak adanya kontrol vektor nyamuk yang efektif di daerah endemis; serta 4) peningkatan sarana transportasi.Kata kunci: kesehatan lingkungan, epidemiologi, demam berdarah dengue


2019 ◽  
Vol 4 (3) ◽  
Author(s):  
Miftah Apriani ◽  
Tridamayanti Tridamayanti

Background: Dengue Hemorrhagic Fever (DHF) or Dengue Hemorrhagic Fever (DHF) is currently one of the public health problems in Indonesia which tends to increase the number of patients and the wider spread. Dengue hemorrhagic fever is an infectious disease caused by dengue virus with clinical manifestations of fever, muscle pain / joint pain accompanied by rashes, thrombocytopenia and hemorrhagic thesis. The data obtained amounted to 81 people. Objective: The objective is to determine the relationship of knowledge, habits of hanging clothes and frequency of draining tubs with the prevention of Dengue Hemorrhagic Fever (DHF). Method: This research was conducted at the Puskesmas Service conducted on May 14 until May 25, 2019. Data analysis used univariate and bivariate analyzes. This research method uses analytical survey method with cross sectional approach. The sample in this study amounted to 81 people using systematic random sampling techniques. Results: From the analysis it was found that there was a relationship of knowledge (ρ-value 0.001), habit of hanging clothes (ρ-value 0.001), and frequency of draining tub (p-value 0,000), with the prevention of DHF. Suggestion: in order to increase counseling about the dangers of dengue fever to the public. Keywords: Dengue Hemorrhagic Fever, Behavior


2020 ◽  
Vol 1 (1) ◽  
pp. 26
Author(s):  
Ghina Rasyidah ◽  
Adinta Anandani

Background: Dengue is a viral disease transmitted by mosquito to humans and becomes a problem for the health of Indonesian people. Dengue Hemorrhagic Fever occurs due to several epidemiological factors. The purpose of this study is to determine the clinical characteristics of adult patients with Dengue Hemorrhagic Fever at Prof. dr. Sulianti Saroso Sunter Infectious Hospital 2018. Method: This Study was an observational descriptive study by taking medical record samples in 49 adult patients Dengue Hemorrhagic Fever in 2018. Results: From the 49 cases of Dengue Haemorrhagic Fever, the highest fender category was male (65,3%), occurred in the 18-25 year age category (38,8%), and the average patient worked as a Private Employee (55,1%). Most patients were hospitalized for the less than 7 days (83,7%). Clinical manifestations were fever (95,9%), nausea (85,7%) and headache (71,4%). Physical examination found was fever (100%) and hepatomegaly (12,2%). Laboratory tests showed normal hematocrit values (71,4%), thrombocytopenia values (87,8%), normal leukocyte values (49%), positive IgG serology tests (83,7%), IgM serology tests (71,4%), Positive IgM and IgG Serology test (69,3%), and NS1 Serology test (2%). Management provided is the administration of intravenous infus fluid drops (100%), PPI (87,8%), H2 Antagonist (4,1%), and Antipiretik (83,7%). The outcome patient is recovered and no complications were found. Conclusion: Dengue Hemorrhagic fever occurs in the age range of 18-25 years with dominant clinical characteristic of fever and thrombocytopenia. And, the most given treatment is Intravena Fluid therapy. 


2012 ◽  
Vol 19 (05) ◽  
pp. 661-667
Author(s):  
AMIR RASHID ◽  
HUMAYUN IQBAL KHAN ◽  
NADEEM- UR-RASOOL

Objective: To study the clinical spectrum of Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) in childrenadmitted in a tertiary care center during 2011 dengue epidemic in Lahore. Setting: This study was conducted in department of PediatricsLahore General Hospital (LGH) / Postgraduate Medical Institute (PGMI) Lahore, Pakistan. Design: Retrospective descriptive study. Period: 1stAugust to 31st October 2011. Method: All the children (<18 years) with clinical features of Dengue Hemorrhagic Fever and Dengue shockSyndrome (DHF/DSS) admitted to the Pediatric ward Lahore General Hospital, Lahore during the period of 1st August to 31st October 2011were enrolled in the study. The clinical manifestation were recorded on a standard questionnaire form. Clinically DHF/DSS cases wereconfirmed in the laboratory by different investigations. All the patient were diagnosed, managed and discharged according to WHO protocol.Results: A total of 254 patients were admitted in the ward labeled as dengue fever (DF) clinically. Out of these 142(55.9 %) were confirmed byserology. Of 254 DF cases 37(14.57%) were labeled as DHF and 02(0.79%) as DSS on their clinical manifestations and fulfilling the WHOcriteria. 55% were male and 45%females. Common symptoms were fever seen in 100%, headache 71.79% and vomiting seen in 58.97% of thecases. The most common bleeding manifestations were epistaxis seen in 69.23% of the cases. Positive IgM was noted in 53.9% and IgG in36.6% cases. A decrease in platelet count and increase in Heamatocrit ( Hct) during stay in ward was noted. Out of 39 patients only one patientexpired (2.56%).


2019 ◽  
Vol 10 (1) ◽  
pp. 76-77
Author(s):  
Hasna Fahmima Haque ◽  
AKM Shaheen Ahmed ◽  
Fuad Bin Bashar ◽  
Rizwana Anjum

Dengue is endemic in Bangladesh and is an emerging infection in many parts of the world. Its clinical manifestations are wide spectrum, may present as mild fever to shock. Muscle hematomas are rare complications in dengue hemorrhagic fever. We report a case of 21-year-old male with dengue hemorrhagic fever who developed right sided iliacus muscle hematoma. He presented with fever, progressive thrombocytopenia and evidence of plasma leakage. During the recovery phase, he developed severe pain in right hip during movement. Diagnosis was confirmed by pelvic computed-tomography scan and he was managed conservatively. Birdem Med J 2020; 10(1): 76-77


2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Wawan Kurniawan

ABSTRAK  Latar belakang: Demam Berdarah Dengue (DBD) disebabkan oleh virus Dengue dapat menyebabkan kematian. Pencegahan DBD yang dianggap paling tepat adalah Pemberantasan Sarang Nyamuk (PSN). Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan pengendalian vektor Demam Berdarah pada siswa sekolah dasar terhadap Maya Index di Majalengka. Metode: Penelitian ini menggunakan desain quasi experiment (pretest-posttest control group design). Sebanyak 4 sekolah terpilih sebagai kelompok intervensi dan 4 sekolah lainnya sebagai kontrol. Subyek penelitian adalah siswa kelas IV-VI yang terdiri dari 171 siswa pada kelompok intervensi dan 163 pada kelompok kontrol. Instrumen yang digunakan adalah formulir pemantauan jentik berkala. Hasil: Jumlah rumah dengan kategori Maya Index tinggi berkurang dari 27,5% menjadi 9,4%. Terjadi penurunan angka BRI kategori tinggi pada kelompok intervensi dari 20,5% menjadi 1,8%. Pada kelompok kontrol tidak terjadi penurunan angka BRI kategori tinggi (22,1%), sebaliknya terjadi penurunan kategori rendah dari 34,4% menjadi 3,7%. Tidak terjadi penurunan angka HRI pada kelompok intervensi maupun kontrol. Kesimpulan: Pelatihan pengendalian vektor Demam Berdarah dapat menurunkan nilai BRI dan Maya Index, tetapi tidak berpengaruh terhadap nilai HRI. Tidak adanya perubahan nilai HRI menunjukkan bahwa kebersihan dan sanitasi lingkungan merupakan faktor yang berpengaruh terhadap probabilitas kejadian demam berdarah. Kata Kunci : Demam Berdarah, Maya Index, pelatihan, pengendalian vektor   ABSTRACT Background: Dengue Hemorrhagic Fever (DHF) caused by Dengue virus could cause death. The most appropriate prevention of Dengue is eradication of mosquito nests (PSN). This study aims to determine the effect of Dengue vector control training on elementary students towards Maya Index in Majalengka. Method: This study used quasi-experimental design (pretest-posttest control group design). A total of 4 schools were selected as intervention groups and 4 other schools as controls. The subjects were students in grades IV-VI consisting of 171 students in the intervention group and 163 in the control group. The instrument used was periodic larva monitoring form. Results: The number of houses with a high Maya Index category in the intervention group decreased from 27.5% to 9.4%. There was a decrease in the high BRI category in the intervention group from 20.5% to 1.8%. In the control group, there was no decrease in the high BRI category (22.1%), on the contrary, there was a decrease in the low category from 34.4% to 3.7%. There was no decrease in HRI rates both of intervention or control groups. Conclusion: Dengue Fever vector control training could decrease the value of BRI and Maya Index, but does not affect the value of HRI. The absence of changes in HRI  indicate that environmental hygiene and sanitation are factors that influence the probability of dengue fever occurrence. Keywords: Dengue Hemorrhagic Fever, Maya Index, training, vector control


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