The impact of fracture liaison services on subsequent fractures and mortality: a systematic literature review and meta-analysis

Abstract Background Morbidity and mortality from candidemia remain unacceptably high. While infectious disease consultation (IDC) is known to lower the mortality from Staphylococcus aureus bacteremia, little is known about the impact of IDC in candidemia. Methods We conducted a retrospective observational cohort study of candidemia patients at a large tertiary care hospital between 2015 and 2019. The crude mortality rate was compared between those with IDC and without IDC. Then, we systematically searched 5 databases through February 2020 and performed a meta-analysis of the impact of IDC on the mortality of patients with candidemia. Results A total of 151 patients met the inclusion criteria, 129 (85%) of whom received IDC. Thirty-day and 90-day mortality rates were significantly lower in the IDC group (18% vs 50%; P = .002; 23% vs 50%; P = .0022, respectively). A systematic literature review returned 216 reports, of which 13 studies including the present report fulfilled the inclusion criteria. Among the 13 studies with a total of 3582 patients, IDC was performed in 50% of patients. Overall mortality was 38.2% with a significant difference in favor of the IDC group (28.4% vs 47.6%), with a pooled relative risk of 0.41 (95% CI, 0.35–0.49). Ophthalmology referral, echocardiogram, and central line removal were performed more frequently among patients receiving IDC. Conclusions This study is the first systematic literature review and meta-analysis to evaluate the association between IDC and candidemia mortality. IDC was associated with significantly lower mortality and should be considered in all patients with candidemia.

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The Impact of Automated Brief Messages Promoting Lifestyle Changes Delivered Via Mobile Devices to People with Type 2 Diabetes: A Systematic Literature Review and Meta-Analysis of Controlled Trials

Journal of Medical Internet Research ◽

10.2196/jmir.5425 ◽

2016 ◽

Vol 18 (4) ◽

pp. e86 ◽

Cited By ~ 79

Author(s):

Carukshi Arambepola ◽

Ignacio Ricci-Cabello ◽

Pavithra Manikavasagam ◽

Nia Roberts ◽

David P French ◽

...

Keyword(s):

Type 2 Diabetes ◽

Literature Review ◽

Mobile Devices ◽

Systematic Literature Review ◽

Meta Analysis ◽

Lifestyle Changes ◽

Controlled Trials ◽

The Impact

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Topics of spirituality in neonatology – Results from a systematic literature review

Spiritual Care ◽

10.1515/spircare-2016-0135 ◽

2016 ◽

Vol 5 (4) ◽

pp. 303-310 ◽

Cited By ~ 1

Author(s):

Michael Thiel

Keyword(s):

Literature Review ◽

Systematic Literature Review ◽

Medical Staff ◽

Case Reports ◽

Meta Analysis ◽

Long Term Outcomes ◽

Difficult Situation ◽

Study Designs ◽

The Impact

AbstractIntroductionThe prognosis of preterms and ill newborns has improved substantially during the last decades. Besides conventional methods, additional interventions play an important role in this development. Managing parents' needs under the circumstances of intensive care can be a crucial aspect of dealing with this difficult situation. But data on this group has not been systematically evaluated so far.MethodWe performed a systematic literature review following the PRISMA criteria. Keywords were neonates, neonatology, newborn, preterm, parents, and spirituality. All study types in English and German were included.ResultsAfter evaluating the abstracts of the initial search results, we considered 33 studies eligible for analysis. Study types are surveys, interviews (qualitative studies), case reports, and reviews. Topics were parents, ethnical differences, medical staff, and palliative care.DiscussionThere is a variety of studies on spirituality in neonatology with a broad spectrum of study types. A meta-analysis is difficult, especially because of the heterogeneity of the study designs, patient numbers and questionnaires used. Although the studies are promising, short-term and long-term outcomes have not been evaluated yet. Interesting endpoints such as the influence on mortality, morbidity and duration of hospital stay cannot be stated. Thus it is too early to derive practical recommendations for the medical staff from these studies.ConclusionAlthough there is a body of data on spirituality in neonatology that addresses several important aspects, even more studies on the impact of parents' needs and the consequences for the medical staff are required.

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Association between fish consumption and risk of dementia: a new study from China and a systematic literature review and meta-analysis

Public Health Nutrition ◽

10.1017/s136898001800037x ◽

2018 ◽

Vol 21 (10) ◽

pp. 1921-1932 ◽

Cited By ~ 11

Author(s):

Aishat T Bakre ◽

Ruoling Chen ◽

Ranjit Khutan ◽

Li Wei ◽

Tina Smith ◽

...

Keyword(s):

Rural Communities ◽

Literature Review ◽

Systematic Literature Review ◽

Dose Response ◽

Fish Consumption ◽

Meta Analysis ◽

Response Relationship ◽

Dose Response Relationship ◽

Cross Sectional ◽

The Impact

AbstractObjectiveTo assess the association of fish consumption with risk of dementia and its dose–response relationship, and investigate variations in the association among low-, middle- and high-income countries.DesignA new community-based cross-sectional study and a systematic literature review.SettingsUrban and rural communities in China; population-based studies systematically searched from worldwide literature.SubjectsChinese adults aged ≥60 years in six provinces (n 6981) took part in a household health survey of dementia prevalence and risk factors. In addition, 33 964 participants from eleven published and eligible studies were included in the systematic review and meta-analysis.ResultsIn the new study in China, 326 participants were diagnosed with dementia (4·7 %); those who consumed any amount of fish in the past two years v. those who consumed no fish had reduced risk of dementia (adjusted OR=0·73, 95 % CI 0·64, 0·99), but the dose–response relationship was not statistically significant. The meta-analysis of available data from the literature and the new study showed relative risk (RR) of dementia of 0·80 (95 % CI 0·74, 0·87) for people with fish consumption; the impact was similar among countries with different levels of income. Pooled dose–response data revealed RR (95 % CI) of 0·84 (0·72, 0·98), 0·78 (0·68, 0·90) and 0·77 (0·61, 0·98) in people with low, middle and high consumption of fish, respectively. Corresponding figures for Alzheimer’s disease were 0·88 (0·74, 1·04), 0·79 (0·65, 0·96) and 0·67 (0·58, 0·78), respectively.ConclusionsGreater consumption of fish is associated with a lower risk of dementia. Increasing fish consumption may help prevent dementia worldwide regardless of income level.

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Are There Associations Between Early Emotional Trauma and Anxiety Disorders? Evidence from a Systematic Literature Review and Meta-Analysis

European Psychiatry ◽

10.1016/j.eurpsy.2015.06.004 ◽

2015 ◽

Vol 30 (6) ◽

pp. 756-764 ◽

Cited By ~ 24

Author(s):

V. Fernandes ◽

F.L. Osório

Keyword(s):

Risk Factor ◽

Social Anxiety ◽

Literature Review ◽

Anxiety Disorders ◽

Systematic Literature Review ◽

Meta Analysis ◽

Control Group ◽

Publication Date ◽

Emotional Trauma ◽

The Impact

AbstractBackgroundPrevious studies indicate a possible association between early emotional trauma (EET) and the development of anxiety disorders (ADs) in adult life. However, no previous studies have compiled the findings of such studies and analyzed their statistical significance. Therefore, the objective of this study was to conduct a systematic literature review and meta-analysis to determine possible associations between EET and three ADs (panic, generalized anxiety, and social anxiety disorders).MethodsA systematic search was conducted in PubMed, PsycInfo, and Scielo with no publication date limitations. A total of 2127 studies were found, 32 studies of which were selected for the systematic review and 13 studies of which were selected for the meta-analysis.ResultsHigh prevalence rates of different EETs were observed among the individuals with ADs (median: 18%–45%). The results of the meta-analysis indicated that individuals with EETs were 1.9- to 3.6-fold more likely to develop ADs compared with a control group of healthy individuals. Emotional traumas were the main risk factor for social anxiety disorder. However, no specific associations were found for the other ADs.ConclusionsEET is a risk factor for ADs, underscoring the importance of preventive measures to combat the development of these disorders. Moreover, the identification of EETs among patients with ADs is essential for implementing remedial measures to minimize the impact and damage arising from this association by decreasing the risk and severity of symptoms and to improve the response rate to treatment of ADs.

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The impact of smoking on prevalence of psoriasis and psoriatic arthritis

Rheumatology ◽

10.1093/rheumatology/keaa179 ◽

2020 ◽

Vol 59 (10) ◽

pp. 2695-2710 ◽

Cited By ~ 2

Author(s):

Ummugulsum Gazel ◽

Gizem Ayan ◽

Dilek Solmaz ◽

Servet Akar ◽

Sibel Z Aydin

Keyword(s):

Psoriatic Arthritis ◽

General Population ◽

Literature Review ◽

Systematic Literature Review ◽

Past History ◽

Meta Analysis ◽

Cochrane Central Register ◽

Central Register ◽

Number Of Patients ◽

The Impact

Abstract Objectives In this systematic literature review and meta-analysis, we aimed to investigate the impact of cigarette smoking on the prevalence and incidence of psoriasis and psoriatic arthritis (PsA). Method We performed a systematic literature review using the MEDLINE, EMBASE and Cochrane Central Register databases. The literature included publications from January 1980 to July 2019. The studies that provided clear information on the number of patients with ever smoking data were included in the meta-analysis. Results The systematic literature review identified 52 and 24 articles for the prevalence of smoking in psoriasis and PsA, respectively. Of these, 16 articles on psoriasis and three and four (general population and psoriasis, respectively) articles on PsA met the criteria and were included in the meta-analysis. The prevalence of ever smoking was increased in psoriasis compared with the general population (OR: 1.84; 95% CI: 1.4, 2.3). For PsA the prevalence of ever smoking was reduced in psoriasis patients (OR: 0.70; 95% CI: 0.60, 0.81), but not changed compared with the general population (OR: 1.10; 95% CI: 0.92, 1.32). Conclusion This meta-analysis showed that ever smoking increases the risk of psoriasis in the general population, but may reduce the risk of PsA in psoriasis patients. The latter may be also due to the collider effect. Whether smoking cessation neutralizes the risk of developing psoriasis requires a well-defined smoking data collection for the past history and this is currently unavailable in the literature.

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Fracture liaison services for osteoporosis in the Asia-Pacific region: current unmet needs and systematic literature review

Osteoporosis International ◽

10.1007/s00198-017-4347-y ◽

2017 ◽

Vol 29 (4) ◽

pp. 779-792 ◽

Cited By ~ 9

Author(s):

Y. -F. Chang ◽

C. -F. Huang ◽

J. -S. Hwang ◽

J. -F. Kuo ◽

K. -M. Lin ◽

...

Keyword(s):

Literature Review ◽

Systematic Literature Review ◽

Unmet Needs ◽

Asia Pacific ◽

Pacific Region ◽

Asia Pacific Region ◽

Fracture Liaison Services ◽

Fracture Liaison

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749. Impact of Infectious Disease Consultation in Patients with Candidemia: A Retrospective study, Systematic Literature Review and Meta-analysis

Open Forum Infectious Diseases ◽

10.1093/ofid/ofaa439.939 ◽

2020 ◽

Vol 7 (Supplement_1) ◽

pp. S421-S422

Author(s):

Takaaki Kobayashi ◽

Alexandre Marra ◽

Marin L Schweizer ◽

Patrick Ten Eyck ◽

Chaorong Wu ◽

...

Keyword(s):

Infectious Disease ◽

Literature Review ◽

Systematic Literature Review ◽

Meta Analysis ◽

Care Hospital ◽

Inclusion Criteria ◽

Research Support ◽

Infectious Disease Consultation ◽

The Impact ◽

Overall Mortality

Abstract Background Morbidity and mortality from candidemia remain unacceptably high. While infectious disease consultation (IDC) is known to lower the mortality from Staphylococcus aureus bacteremia, little is known on the impact of IDC in candidemia. Methods We conducted a retrospective observational cohort study of candidemia patients at a large tertiary care hospital between 2015 and 2019. All patients aged ≥18 years with blood cultures positive for Candida species were included. We only included the first episode of candidemia. Exclusion criteria were death or transfer to the palliative care unit within 48 hours from the time cultures became positive. The crude mortality rate was compared between those with IDC and without IDC. Then, we systematically searched five publication-databases through February 2020 and performed a meta-analysis of the impact of IDC on mortality of patients with candidemia. The study protocol has been submitted to the International Prospective Register for Systematic Reviews (PROSPERO) database (ID 156939) on April 2020. Results A total of 151 patients at our institution met the inclusion criteria, 129 (85%) of whom received IDC. Thirty-day, and 90-day mortality rates were significantly lower in the IDC group (18% vs 50%, P = .002; 23% vs 50%, P = .0022, respectively). Our systematic literature review returned 216 reports, of which, 13 studies including ours fulfilled the inclusion criteria. Among the 13 studies with a total 3687 patients, IDC was performed in 49% of patients. Mortality numbers were available in 10 studies. Overall mortality was 38.2% with a significant difference in favor of the IDC group (28.4% and 47.6%) with a pooled relative risk of 0.41 [95% Cl 0.35-0.49]. Ophthalmology referral (61%; 790/1279 and 21%; 273/1304, P < 0.001), echocardiogram (54%; 662/1219 and 28%; 369/1296, P < 0.001), and central line removal (78%; 830/1069 and 61%; 686/1116, P < 0.02) were performed more frequently among patients receiving IDC. Overall mortality Conclusion This study is the first systematic literature review and meta-analysis to evaluate the association between IDC and candidemia mortality. IDC was associated with a lower mortality and should be standard of care in all patients with candidemia. Disclosures Dimitrios Farmakiotis, MD, Astellas (Grant/Research Support) Paul Auwaerter, Collidion (Consultant)DiaSorin (Consultant)Johnson and Johnson (Shareholder)MicroB-Plex (Research Grant or Support)Shionogi (Consultant) Daniel Diekema, bioMerieux, Inc (Grant/Research Support)JMI Laboratories (Consultant)

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