Breast density measured volumetrically in a clinical environment: cross-sectional study with photon counting technology

2019 ◽  
Vol 179 (3) ◽  
pp. 755-762 ◽  
Author(s):  
Jean L. Browne ◽  
Lilian Casas ◽  
Guillermo Santandreu ◽  
Ignacio Rodriguez ◽  
Beatriz Navarro ◽  
...  
Keyword(s):  
Breast Density ◽  
Photon Counting ◽  
Cross Sectional Study ◽  
Clinical Environment ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Breast density in women with premature ovarian failure or postmenopausal women using hormone therapy: analytical cross-sectional study

2010 ◽  
Vol 128 (4) ◽  
pp. 211-214 ◽  
Author(s):  
Patrícia Magda Soares ◽  
César Cabello ◽  
Luis Alberto Magna ◽  
Eduardo Tinois ◽  
Cristina Laguna Benetti-Pinto
Keyword(s):  
Hormone Therapy ◽  
Postmenopausal Women ◽  
Breast Density ◽  
Premature Ovarian Failure ◽  
Cross Sectional Study ◽  
Ovarian Failure ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Impact

CONTEXT AND OBJECTIVE: Studies on postmenopausal women have reported increased risk of breast cancer relating to the type and duration of hormone therapy (HT) used. Women with premature ovarian failure (POF) represent a challenge, since they require prolonged HT. Little is known about the impact of prolonged HT use on these women's breasts. This study aimed to evaluate the effects of one type of HT on the breast density of women with POF, compared with postmenopausal women. DESIGN AND SETTING: Cross-sectional study at the Department of Obstetrics and Gynecology, Universidade Estadual de Campinas (Unicamp). METHODS: 31 women with POF and 31 postmenopausal women, all using HT consisting of conjugated equine estrogen combined with medroxyprogesterone acetate, and matched according to HT duration, were studied. Mammography was performed on all subjects and was analyzed by means of digitization or Wolfe's classification, stratified into two categories: non-dense (N1 and P1 patterns) and dense (P2 and Dy). RESULTS: No significant difference in breast density was found between the two groups through digitization or Wolfe's classification. From digitization, the mean breast density was 24.1% ± 14.6 and 18.1% ± 17.2 in the POF and postmenopausal groups, respectively (P = 0.15). Wolfe's classification identified dense breasts in 51.6% and 29.0%, respectively (P = 0.171). CONCLUSION: There was no difference in breast density between the women with POF and postmenopausal women, who had used HT for the same length of time. These results may help towards compliance with HT use among women with POF.

scholarly journals Comparing Visually Assessed BI-RADS Breast Density and Automated Volumetric Breast Density Software: A Cross-Sectional Study in a Breast Cancer Screening Setting

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0136667 ◽  
Author(s):  
Daniëlle van der Waal ◽  
Gerard J. den Heeten ◽  
Ruud M. Pijnappel ◽  
Klaas H. Schuur ◽  
Johanna M. H. Timmers ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
Breast Density ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Dietary intake and breast density in high-risk women: a cross-sectional study

2007 ◽  
Vol 9 (5) ◽  
Author(s):  
Marilyn Tseng ◽  
Celia Byrne ◽  
Kathryn A Evers ◽  
Mary B Daly
Keyword(s):  
High Risk ◽  
Dietary Intake ◽  
Breast Density ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
High Risk Women

scholarly journals The Association Between Breast Density and Gut Microbiota Composition at 2 Years Post-Menarche: A Cross-Sectional Study of Adolescents in Santiago, Chile

2021 ◽  
Vol 11 ◽  
Author(s):  
Lara S. Yoon ◽  
Jonathan P. Jacobs ◽  
Jessica Hoehner ◽  
Ana Pereira ◽  
Juan Cristóbal Gana ◽  
...  
Keyword(s):  
Breast Density ◽  
Gut Microbiome ◽  
Beta Diversity ◽  
Diversity Index ◽  
Alpha Diversity ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Linear Modeling ◽  
Microbial Composition ◽  
Cross Sectional

The gut microbiome has been linked to breast cancer via immune, inflammatory, and hormonal mechanisms. We examined the relation between adolescent breast density and gut microbial composition and function in a cohort of Chilean girls. This cross-sectional study included 218 female participants in the Growth and Obesity Cohort Study who were 2 years post-menarche. We measured absolute breast fibroglandular volume (aFGV) and derived percent FGV (%FGV) using dual energy X-ray absorptiometry. All participants provided a fecal sample. The gut microbiome was characterized using 16S ribosomal RNA sequencing of the V3-V4 hypervariable region. We examined alpha diversity and beta diversity across terciles of %FGV and aFGV. We used MaAsLin2 for multivariable general linear modeling to assess differential taxa and predicted metabolic pathway abundance (MetaCyc) between %FGV and aFGV terciles. All models were adjusted for potential confounding variables and corrected for multiple comparisons. The mean %FGV and aFGV was 49.5% and 217.0 cm3, respectively, among study participants. Similar median alpha diversity levels were found across %FGV and aFGV terciles when measured by the Shannon diversity index (%FGV T1: 4.0, T2: 3.9, T3: 4.1; aFGV T1: 4.0, T2: 4.0, T3: 4.1). %FGV was associated with differences in beta diversity (R2 =0.012, p=0.02). No genera were differentially abundant when comparing %FGV nor aFGV terciles after adjusting for potential confounders (q > 0.56 for all genera). We found no associations between predicted MetaCyc pathway abundance and %FGV and aFGV. Overall, breast density measured at 2 years post-menarche was not associated with composition and predicted function of the gut microbiome among adolescent Chilean girls.

scholarly journals Age and Ethnic Differences in Volumetric Breast Density in New Zealand Women: A Cross-Sectional Study

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e70217 ◽  
Author(s):  
Lis Ellison-Loschmann ◽  
Fiona McKenzie ◽  
Ralph Highnam ◽  
Andrew Cave ◽  
Jenny Walker ◽  
...  
Keyword(s):  
New Zealand ◽  
Ethnic Differences ◽  
Breast Density ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Conocimiento de adultos jóvenes sobre el accidente cerebrovascular en una ciudad del sur de Portugal

2019 ◽  
Vol 18 (4) ◽  
pp. 423-458
Author(s):  
Maria Margarida Santana Fialho Sim-Sim ◽  
Maria José Abrantes ◽  
Maria Gorete Mendonça dos Reis ◽  
Elsa Maria Garção Pires ◽  
Manuel Agostinho Matos Fernandes ◽  
...  
Keyword(s):  
Young Adults ◽  
Risk Behavior ◽  
Cross Sectional Study ◽  
Health It ◽  
Sources Of Information ◽  
Clinical Environment ◽  
Sectional Study ◽  
Ethical Aspects ◽  
Cross Sectional ◽  
Parental Figures

Aim: To analyze the knowledge of young adults about stroke. Method: Quantitative, cross-sectional study in a non-clinical environment. Convenience simple. Through the elementary school of Evora, parental figures were asked to participate. Ethical aspects were respected. Self-fill questionnaire returned after one week. Results: 147 men (44.5%) participated, 183 women (55.5%), with a mean age of 42.25 years (SD = 5.00). The most commonly reported risk behavior for stroke is smoking (56.5%), followed by hypertension (28.8%) and hypercholesterolemia (28.8%). The main sources of information are television (93.2%) and friends (89.4%). In immediate witness assistance, the attitudes of the participants would be mostly incorrect. There is a gap between knowledge and the respective action. Conclusions: there is a risk behavior, observed also among other studies, with a population of older people. The results show a lack of literacy in health. It will be urgent to develop projects that inform and exemplify the risks of behavior. The performance of the person with stroke must be taught and trained to the citizen. The dissemination of information about stroke is urgent in the region. Young adults, as educators, can intervene to reduce cases in the generation of their children. Objetivo: Analizar el conocimiento de adultos jóvenes sobre el accidente cerebrovascular. Métodos: Estudio cuantitativo, transversal, en ambiente no-clínico. Muestra de conveniencia de adultos. A través de los niños de las escuelas de la ciudad de Évora, se pidió la participación de las figuras parentales. Los aspectos éticos fueron respetados. Cuestionario de auto rellenado devuelto pasado una semana. Resultados: Participaron 147 hombres (44.5%), 183 mujeres (55.5%), con la edad media de 42.25 años (DP=5.00). El comportamiento de riesgo más referido para el accidente cerebrovascular es el tabaquismo (56.5%), siguiéndo la hipertensión (28.8%) y la hipercolesterolemia (28.8%). Las principales fuentes de información son la televisión (93,2%) y los amigos (89,4%). En la ayuda inmediata, las actitudes de los participantes serían en la mayoría incorrectas, existiendo un desfase entre el conocimiento y la respectiva actuación. Conclusiones: Existen entre los participantes comportamientos de riesgo observados en otros estudios con población de personas mayores. Los resultados detectan déficit de alfabetización en salud. Será urgente el desarrollo de proyectos que informen y ejemplifiquen, los riesgos de los comportamientos. La actuación ante la persona con accidente cerebrovascular, debe ser objeto de enseñanza y de entrenamiento al ciudadano. La divulgación de información sobre accidente cerebrovascular es urgente en la región. Los adultos jóvenes, como educadores, pueden intervenir para disminuir los casos en la generación de sus hijos. Objetivo: Analizar el conocimiento de adultos jóvenes sobre el accidente cerebrovascular. Métodos: Estudio cuantitativo, transversal, en ambiente no-clínico. Muestra de conveniencia de adultos. A través de los niños de las escuelas de la ciudad de Évora, se pidió la participación de las figuras parentales. Los aspectos éticos fueron respetados. Cuestionario de auto rellenado devuelto pasado una semana. Resultados: Participaron 147 hombres (44.5%), 183 mujeres (55.5%), con la edad media de 42.25 años (DP=5.00). El comportamiento de riesgo más referido para el accidente cerebrovascular es el tabaquismo (56.5%), siguiéndo la hipertensión (28.8%) y la hipercolesterolemia (28.8%). Las principales fuentes de información son la televisión (93,2%) y los amigos (89,4%). En la ayuda inmediata, las actitudes de los participantes serían en la mayoría incorrectas, existiendo un desfase entre el conocimiento y la respectiva actuación. Conclusiones: Existen entre los participantes comportamientos de riesgo observados en otros estudios con población de personas mayores. Los resultados detectan déficit de alfabetización en salud. Será urgente el desarrollo de proyectos que informen y ejemplifiquen, los riesgos de los comportamientos. La actuación ante la persona con accidente cerebrovascular, debe ser objeto de enseñanza y de entrenamiento al ciudadano. La divulgación de información sobre accidente cerebrovascular es urgente en la región. Los adultos jóvenes, como educadores, pueden intervenir para disminuir los casos en la generación de sus hijos.

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