scholarly journals Breast density in women with premature ovarian failure or postmenopausal women using hormone therapy: analytical cross-sectional study

2010 ◽  
Vol 128 (4) ◽  
pp. 211-214 ◽  
Author(s):  
Patrícia Magda Soares ◽  
César Cabello ◽  
Luis Alberto Magna ◽  
Eduardo Tinois ◽  
Cristina Laguna Benetti-Pinto

CONTEXT AND OBJECTIVE: Studies on postmenopausal women have reported increased risk of breast cancer relating to the type and duration of hormone therapy (HT) used. Women with premature ovarian failure (POF) represent a challenge, since they require prolonged HT. Little is known about the impact of prolonged HT use on these women's breasts. This study aimed to evaluate the effects of one type of HT on the breast density of women with POF, compared with postmenopausal women. DESIGN AND SETTING: Cross-sectional study at the Department of Obstetrics and Gynecology, Universidade Estadual de Campinas (Unicamp). METHODS: 31 women with POF and 31 postmenopausal women, all using HT consisting of conjugated equine estrogen combined with medroxyprogesterone acetate, and matched according to HT duration, were studied. Mammography was performed on all subjects and was analyzed by means of digitization or Wolfe's classification, stratified into two categories: non-dense (N1 and P1 patterns) and dense (P2 and Dy). RESULTS: No significant difference in breast density was found between the two groups through digitization or Wolfe's classification. From digitization, the mean breast density was 24.1% ± 14.6 and 18.1% ± 17.2 in the POF and postmenopausal groups, respectively (P = 0.15). Wolfe's classification identified dense breasts in 51.6% and 29.0%, respectively (P = 0.171). CONCLUSION: There was no difference in breast density between the women with POF and postmenopausal women, who had used HT for the same length of time. These results may help towards compliance with HT use among women with POF.

2020 ◽  
pp. 20-23
Author(s):  
Sneha Upadhyay ◽  
Jyoti Bhavthankar ◽  
Mandakini Mandale ◽  
Nivedita Kaorey

Background: Asthma and its medications have been linked to oral diseases in asthmatic children. Aim: Assessment of the dental caries status, salivary Streptococcus mutans count and S. mutans colony score in children receiving inhaled anti asthmatic medications and their comparison in healthy children Material and Method: A cross-sectional study was performed on 40 asthmatic children and 40 healthy children in the age group of 6-14 years. DMFT/deft indices were calculated and saliva samples were collected. Diluted saliva was inoculated on MSB agar plates. S. mutans count and colony score were analysed after 24-48 hours of inoculation. Results: Statistically significant difference was observed in the mean DMFT/deft index, salivary S. mutans load and S. mutans colony score in children of the asthmatic group and control group. Conclusion: Prevalence of dental caries and cariogenic bacteria is higher in asthmatic children.


2021 ◽  
Author(s):  
Nevena Ćorić ◽  
Anita Jurić ◽  
Andrea Karlovic

Abstract Background: Pandemic caused by the COVID-19 virus brought tremendous changes in the lifestyle of adolescents, about which numerous studies have been published. Due to extended restrictions, long term impact should be investigated.Methods: This cross-sectional study enrolled 953 voluntary participants aged 14 to 21, from different regions of B&H. Participants were asked to complete an online 37-item survey, regarding socio-demographics, geographic, social characteristics, dietary and lifestyle habits, physical activity, including their consumption of dietary, vitamin and mineral supplements. They also needed to provide information about their weight, height and weight change during the entire period of the COVID-19 pandemic from March 2020 until the end of November when the study was completed. For data entry and analysis, SPSS (version 25) and Microsoft Excel were used.Results: At the time of completing the survey, a slightly lower BMI of participants was noticed compared to the time before the pandemic. A statistically significant difference was determined between males and females BMI, boys BMI was slightly higher. Females gained and men lost BW. Increased intake of unhealthy types of food was associated with weight change. Increased mental stress during the pandemic was associated with dietary changes, respectively with decreased as also increased food amount. High percent of participants (40.4%) who increased their physical activity did not alter their eating in the form of the food amount. This study reported use of some dietary supplements which have not been used before the pandemic by 63.5% participants.Conclusions: This paper presents a unique insight into the changing lifestyle and eating habits of adolescents in B&H during lockdown and post-lockdown period of research. Considering that pandemic is still ongoing, data from study like this may be useful to create further steps in battling the pandemic.


BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e038572
Author(s):  
Qin-wei Qiu ◽  
Jing Li ◽  
Jia-yu Li ◽  
Yong Xu

ObjectivesFew data on the association between housing structure and depression among rural elders in China are available. We examined the impact of built forms on depression.DesignThis is a cross-sectional study.SettingA representative sample of rural residents aged 60 years or older in China.ParticipantsA total of 5090 older adults in 2019 in rural Suzhou, China.Outcome measuresAssociations of built form with odds of probable and possible depression.ResultsThere was significant difference among elders living in varied sizes of house. Older age (vs 60–64 years: 75–79 years AdjOR, 1.737; 95% CI, 1.309 to 2.305; ≥80 years AdjOR, 2.072; 95% CI, 1.439 to 2.981), male sex (AdjOR, 0.719; 95% CI, 0.593 to 0.871), single (AdjOR, 1.303; 95% CI, 1.032 to 1.646), self-care disability (AdjOR, 4.761; 95% CI, 3.960 to 5.724), three or more chronic diseases (AdjOR, 2.200; 95% CI, 1.657 to 2.920), living alone (AdjOR, 1.443; 95% CI, 1.059 to 1.966), living in cottage (AdjOR, 1.426; 95% CI, 1.033 to 1.967), living space (vs <50 m2: 201–250 m2 AdjOR, 0.566; 95% CI, 0.359 to 0.893; >250 m2 AdjOR, 0.337; 95% CI, 0.223 to 0.511) and space per person (vs <30 m2: 30- m2 AdjOR, 0.502; 95% CI, 0.362 to 0.697; 40- m2 AdjOR, 0.473; 95% CI, 0.347 to 0.646; 50- m2 AdjOR, 0.418; 95% CI, 0.339 to 0.515) were associated with risk of depression among Chinese rural elders.ConclusionThe built form was significantly and meaningfully associated with depression among Chinese rural elders. More attention should be paid to preventing mental illness among the rural elderly living in the small housing area and cottages in China.


Author(s):  
Aditi Agrawal ◽  
Sanjay Gehlot ◽  
Ashok Singhal ◽  
Amandeep .

Background: People with mental illnesses experience extreme stigmatization and discrimination despite their ubiquitous presentation. Studies have reported that these negative stereotypes are shared by health care professionals too. Attitude of undergraduate medical students towards psychiatry is vital as it reflects their willingness to deal with psychiatric and behavioral disorders in general practice.Methods: A descriptive cross-sectional study was conducted in a government medical college in Rajasthan to explore the impact of sociodemographic variables and undergraduate psychiatry training on the attitude of medical students towards mental illness and psychiatry. 105 first year MBBS students and 75 interns participated in the study. Attitude towards mental illness (AMI) scale and attitude towards psychiatry-30 (ATP-30) scale were used to document AMI and ATP respectively. Data collected were analyzed using SPSS statistical software and appropriate tests were used to compare mean scores of both groups.Results: There was no statistically significant difference on AMI and ATP scores between the undergraduate medical students and interns. Females, students belonging to urban setting and more educated families had a favorable attitude towards psychiatric patients. A notable shift in scores on ATP scale towards positive side was reflected between male MBBS students and interns and among students coming from rural background with exposure to medical curriculum.Conclusions: No attitude change was observed in majority of participants indicating need for greater emphasis on mental health and psychiatry. 


2014 ◽  
Vol 4 (2) ◽  
pp. 50-54
Author(s):  
Radish Kumar Balasubramanium ◽  
Jayashree S Bhat

ABSTRACT Background Previous studies on effects of menopause on voice characteristics have not compared the voice characteristics before, during and after menopause. It is also possible that these voice changes cannot be captured by traditional acoustic measures such as frequency and amplitude perturbation measures. Hence a robust acoustic tool such as cepstrum was chosen to capture these vocal changes before, during and after menopause and hence the present study was attempted. Method The present study followed a cross-sectional study design. The participants consisted of 25 premenopausal women, 25 perimenopausal women and 25 postmenopausal women. Sustained production of/a/ and narration was recorded using Z tool and cepstral peak prominence (CPP) and smoothened cepstral peak prominence (CPPS) was analyzed. Results The results of one-way ANOVA revealed that there was a significant main effect of the group at p < 0.05 for all the cepstral measures targeted in the study. Post hoc analysis indicated that there was no significant difference between pre and perimenopausal women for all the cepstral measures at p < 0.05. However, there was a significant difference between pre and postmenopausal women and peri and postmenopausal women at p < 0.05. These results suggests that postmenopausal women had overall good voice quality than pre and perimenopausal women. Conclusion Results indicated that post menopausal women had increased cepstral measures when compared to pre and perimenopausal women. Further, studies are required to correlate laryngeal examination and hormonal levels with that of the voice changes before, during and after menopausal women. How to cite this article Balasubramanium RK, Bhat JS. Cepstral Characteristics of Voice before, during and after Menopause: A Cross-sectional Study. Int J Phonosurg Laryngol 2014;4(2):50-54.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 66-66
Author(s):  
Kara Poindexter ◽  
Christina Sciarrillo ◽  
Janice Hermann ◽  
Sam Emerson

Abstract Objectives Elevated postprandial triglycerides (TG) are a risk factor for cardiovascular disease (CVD). Although some evidence suggests that older adults exhibit greater postprandial TG than younger adults, it is unknown how postprandial lipid tolerance changes across the spectrum of older adulthood. This cross-sectional study examines postprandial TG responses across the spectrum of aging, as well as factors that may modify this response. Methods We are recruiting individuals into four age categories (age 50–59, 60–69, 70–79, 80–89 years), with an equal number of participants and sex distribution in each group. Participants undergo body composition testing via bioelectrical impedance analysis and complete a 130-item food frequency questionnaire. Participants return to the lab after a 10-hour fast and blood is drawn both before and 4 hours after consumption of a high-fat meal (9 kcal/kg body mass; 73% fat, 26% CHO) to determine fasting and postprandial TG. Results Thirty participants (50’s: n = 12; 60’s: n = 11; 70’s: n = 4; 80’s: n = 3) have completed the study (total N = 60). There was no difference (P = 0.52) in BMI across age groups (50’s: 29.5 ± 5.4 kg/m2; 60’s: 29.1 ± 5.5 kg/m2; 70’s: 25.9 ± 3.8 kg/m2; 80’s: 26.1 ± 1.6 kg/m2). There was also no difference (P = 0.68) in body fat (BF%) across age groups (50’s: 37.5 ± 7.2%; 60’s: 39.53 ± 7.0%; 70’s: 43.6 ± 8.2%; 80’s: 39.5 ± 18.1%). Similarly, there was no difference (P = 0.76) in fasting TG across age groups (50’s: 98.8 ± 40.6 mg/dL; 60’s: 117.9 ± 83.3 mg/dL; 70’s: 105.3 ± 39.7 mg/dL; 80’s: 79.7 ± 31.7 mg/dL), nor was there a difference (P = 0.74) in 4-hr TG (50’s: 162.3 ± 70.8 mg/dL; 60’s: 187.5 ± 105.5 mg/dL; 70’s: 181.8 ± 89.6 mg/dL; 80’s: 130.7 ± 55.1 mg/dL). Lastly, there was no difference (P = 0.16) in fruit and vegetable (FV) intake (50’s: 4.4 ± 1.9 servings/day (s/d); 60’s: 8.2 ± 5.5 s/d; 70’s: 6.2 ± 4.6 s/d; 80’s: 7.9 ± 2.4 s/d). Conclusions At this point in the study, it cannot be concluded that there is a significant difference in fasting or postprandial TG across aging strata, possibly due to no differences in BMI, BF%, or FV intake. When complete, this study will provide valuable insight with regard to the impact of aging and other lifestyle factors on postprandial lipemia and subsequent CVD risk. Funding Sources This project is funded by the Donna Cadwalader Research and Development Grant.


Author(s):  
Joana Meneses Martins ◽  
Liliana Gavinha Costa ◽  
Ana Lidia Carvalho ◽  
Maria Conceição Manso ◽  
Sandra Gavinha ◽  
...  

Background: The objective was to determine if asymmetric facial features, nasal and chin deviations, affect the perception of attractiveness of a dental midline angulation, and if it is consistent among both dentists and laypeople. It was also analyzed if factors, such as the sex, age group of the participants and the dentist’s area of operation are relevant in their assessment. Methods: A cross-sectional study, approved by the Ethics Committee of Fernando Pessoa University. From a symmetrical facial model (SFM) image, a natural-looking asymmetrical face was created. Based on this asymmetric facial model six images were created, with different directions and degrees of inclination of the dental midline. In total, 236 laypersons and 242 dentists completed the online questionnaire where they rated the self-perception of attractiveness of the eight images (VAS scale from 0 to 10). Non-parametric comparisons (IBM© SPSS Statistics vs. 27.0, p < 0.05). Results: The results showed a significant difference in the perception of attractiveness between laypeople and dentists. This finding was consistent regarding every image, except for the SFM. The factors, sex of the people participating and dentist’s area of operation, seemed only to contribute to a significant difference in the perception when it came to the SFM. The perceived attractiveness of the images, for dentists and laypersons, did not differ by age group of the participant, apart from images 6 and 8. Conclusions: Dentists are more rigorous about dental midline inclinations than laypersons. The perception of attractiveness was affected by the age group and sex of the participants and the dentist’s area of operation.


Author(s):  
Pothiraj Pitchai ◽  
Reshma Gurav ◽  
Srishti Chauhan

Purpose: Falls are an emerging public health problem causing a cascade of medical, functional, and socio-economic consequences. Apart from other widely explored risk factors affecting balance, anthropometric factors are also known to have an impact on balance. However, this relationship hasn’t been studied extensively in older adults. This study aimed to evaluate the relationship between the anthropometric factors such as Body Mass Index (BMI), Body Fat Mass (BFM), Waist-Hip Ratio (WHR), Lower Limb Length (LLL), Foot Length (FL) and balance in the elderly among fallers and non-fallers. Method: This cross-sectional study was performed on 100 fallers and 100 non-fallers, aged 60 years and above. These participants were recruited by a stratified random sampling technique from Navi Mumbai region. All the above anthropometric factors were measured and recorded. Each participant’s balance was assessed using the Mini-BESTest scale. Obtained scores were analysed in SPSS software; descriptive statistics, Spearman correlation coefficient, and Z scores were applied. Results: A sample size of 100 non-fallers, 50% male and 50% females, participated in this study. Among those participants classified as “fallers,” 56% were males and 44% were females. The mean age of the non-fallers was 66±5.01 and the mean age of the fallers was 67.72±6.73. In fallers, WHR showed good negative correlation (r= -.807), BFM as moderate (r= -.577) and BMI as fair (r= -.426) whereas in non-fallers, BMI showed moderate (r= -.546) and fair negative correlation for both WHR (r= -.303) and BFM (r= -.441). However, LLL and FL in both groups show little or no correlation. The Association of all anthropometric factors with the balance between fallers and non-fallers showed no-significant difference. It may be inter-group variance for age, gender and BMI, as participants were not matched for these variables during the recruiting phase. Additionally, the reason for the fall was not explored, thus adding to the limitations of our study. Conclusion: This study demonstrated the impact of increased WHR, BFM and BMI on balance in the elderly fallers and non-fallers. Thus, it is important to screen these factors while assessing biological risk factors for predicting falls. This study further recommends exploring the normative value for anthropometric factors in a healthy elderly population.


Maturitas ◽  
2018 ◽  
Vol 111 ◽  
pp. 77-81 ◽  
Author(s):  
Jingfei Zhang ◽  
Tingyue Zhang ◽  
Lisheng Yu ◽  
Qianying Ruan ◽  
Lingxue Yin ◽  
...  

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