Aerodynamic Design, Analysis and Validation of a Small Blended-Wing-Body Unmanned Aerial Vehicle

This paper describes the aerodynamic design and assessment of a blended-wing–body (BWB) configuration under the distributed electric propulsion (DEP) installation constraints. The aerodynamic design rationale and process is described, as well as how the DEP system is considered and simplified in the optimization design process. Both the BWB configuration and the DEP induced effects are numerically simulated and analyzed using the Reynolds Averaged Navier–Stokes (RANS) computational fluid dynamics (CFD) flow solvers. To further demonstrate the feasibility and reliability of the design approach, the wind tunnel tests of a scaled model of the designed BWB configuration are carried out, and both the aerodynamic characteristics and the BWB surface flow are measured and analyzed. The results indicate the reliability and feasibility of the optimization design method introduced in this paper.

Numerical Analysis of Pressure Profiles and Energy Dissipation across Stepped Spillways Having Curved Risers

In this study, curved risers stepped spillways models based on the increasing angle of suspension were tested to check for improvement in energy dissipation and pressure distributions. Four fourteen-steps stepped spillway models with a slope 1:0.84 were selected, using Froude’s number non-dimensional similarity. The risers of steps were made curved, based on three angles of suspensions, i.e., 30°, 60°, and 90°. The simulations were performed by FLOW 3D software and by the turbulence model Renormalization Group (RNG) for discharges between 0.020 and 0.068 m3/s followed by the model calibration. The 3D Reynolds-averaged Navier–Stokes equations were solved, which included sub-grid models for air entrainment, density evaluation, and drift–flux, to capture free-surface flow over the stepped spillway. It was estimated that curving the risers increases the energy dissipation up to three percent for lower flow rates, whereas it has no significant impact on energy dissipation for higher flow rates. It was found that in simply stepped spillway lower steps dissipate more energy as compared to curved risers stepped where energy dissipation is shifted to higher steps. On the other hand, curved risers stepped spillways showed lower values of negative pressures as compared to the simply stepped spillway. It was seen that a higher energy dissipating step as experienced more negative pressures as compared to the lower energy dissipating step.

Генерация поверхностного потока жидкости в каналах капиллярными колебаниями и волнами

The generation of a directed flow on the water surface in channels with sources and resonators of capillary oscillations is detected and investigated. The surface flow is caused by the movement of the liquid through the gaps between the resonators, as well as between the resonator and the channel walls, under a curved surface that is locally deformed by the sources of capillary vibrations, the transfer of energy of the locally curved surface of the liquid by capillary waves, and the transmission of wave momentum to the particles of the liquid surface in one direction. It is shown that capillary waves together with the energy transfer an excess surface, the flux density of which is equal to the flux of the surface deformation. Moving devices with a capillary-wave accelerator of the surface liquid flow are demonstrated.

Monoclonal Antibody Against Sortilin Induces Apoptosis in Human Breast Cancer Cells

Background: Sortilin has an important role in various malignances and can be used as a promising target to eradicate cancer cells. Methods: In this study, the expression of sortilin in 4T1 and MDA-MB231 cell lines was evaluated by flow cytometry and immunocytochemistry. Apoptosis assay was also applied to evaluate apoptosis induction in 4T1 and MDA-MB231 cell lines. Results: Based on cell surface flow cytometry results, anti-sortilin (2D8-E3) mAb could recognize sortilin molecules in 79.2% and 90.3% of 4T1 and MDA-MB231 cell-lines, respectively. The immunocytochemistry staining results confirmed sortilin surface expression. Apoptosis assay indicated that anti-sortilin mAb could induce apoptosis in 4T1 and MDA-MB231 cell lines. Conclusion: Our study revealed the important role of surface sortilin in breast carcinoma cell survival and its possible application as a therapeutic agent in cancer targeted therapies.

Analysis of Severe Accident in Complex System Reactor Using Moving Particle Semi-Implicit (MPS) Method

The very complex structure of nuclear reactors is one aspect of the cause of severe accidents in nuclear reactors. To prevent serious accidents, analysis is needed on the reactor design before the reactor is built. Reactor accident analysis can be done using the Moving Particle Semi-Implicit method. The Moving Particle Semi-Implicit method is excellent in simulating the movement of liquid fuel in a reactor because it can analyze the free surface flow of an incompressible liquid without using a mesh grid. Simulations were carried out using three types of fluids with different viscosities and densities such as water, oil, and wax. The simulation results show that the water takes the fastest time to drain all the particles and the oil takes the longest time. From the simulation results, it can be determined that the kinematic viscosity of a liquid affects its flow velocity.

Hydrological Conditions Of Drained Lake Basins Of The Anadyr Lowland Under Changing Climatic Conditions

The lakes of the Arctic lowlands are both the unique indicator and the result of climatic and permafrost changes. Remote sensing methods and field measurements were used to consider the patterns and features of the morphometric indicators dynamics of the Anadyr lowland lakes over 65 years. We analyzed the parameters of 36 lakes with an area of 0.02–0.3 km2 located in the bottoms of drained lake basins, in river floodplains, on sea-shore terraces. Field studies were conducted on 22 typical lakes. The considered dynamics of seasonal thawing are based on the monitoring of the active layer for 1994–2020. Due to an increase of mean annual air temperature by 1.8 °C, as well as an increase and then a decrease in the mean annual precipitation by 135 mm, the average share of a lake area in the study area decreased by 24%. It is shown for the first time that cryogenic processes of the lacustrine coastal zone affect the change in the area of lakes simultaneously with the influence of precipitation and air temperature. Based on field observations, we considered two causes of natural drainage: discharge of the lakes through newly formed thermokarst and thermoerosional surface flow channels and decrease in suprapermafrost groundwater recharge as a result of changing depth of seasonally thawed active layer in the coastal zone.

Nanofluid Transport through a Complex Wavy Geometry with Magnetic and Permeability Effects

The current article incorporates the numerical investigation of heat exchange rate and skin friction carried out through nanofluid saturated with thermally balanced porous medium over a rough horizontal surface that follows the sinusoidal waves. The effects of the external magnetic field are discussed by managing the magnetic field strength applied normally to the flow pattern. The occurring partial differential governing equations are grasped through a strong numerical scheme of the Keller box method (KBM) against the various parameters. The findings are elaborated through tables and diagrams of velocity, temperature, skin friction, Nusselt number, streamlines, and heat lines. The percentage increase in Nusselt number and coefficient of skin friction over the flat and wavy surface is calculated which leads to the conclusion that the copper (Cu) nanoparticles are better selected as compared to the silver (Ag) for heat transfer enhancement. It is also evident from sketches that the current analysis can be used to enhance the surface drag force by means of nanoparticles. It is a matter of interest that the magnetic field can be used to manage the heat transfer rate in such a complicated surface flow. The current readings have been found accurate and valid when compared with the existing literature.

On the behavior of nonlinear hydrodynamic coefficients of a submerged cylinder beneath the water surface

This study aims at numerically exploring the behavior of flow fields and nonlinear hydrodynamic coefficients of a horizontal cylinder beneath the free surface flow considering the effects of nonlinear surface waves and various cylinder shapes. The computational model is based on two-dimensional incompressible Navier-Stokes solvers along with the treatment of the free surface flow using the volume of fluid method. The effect of the turbulent flow is also considered by using the shear stress transport turbulence model. The simulation result of a benchmark case study of the submerged cylinder is first validated with available experiment data, where a mesh convergence analysis is also performed. Afterward, the flow fields and hydrodynamic force coefficients around the cylinder surface are analyzed, and the influences of various cylinder shapes and Reynolds numbers on the hydrodynamic coefficients are investigated. A state diagram representing the hydrodynamic behavior including stable and unstable stages is finally proposed; this is an important criterion for the practice design of submerged civil structures under the free surface flow.