scholarly journals Tattoo tomography: Freehand 3D photoacoustic image reconstruction with an optical pattern

Author(s):  
Niklas Holzwarth ◽  
Melanie Schellenberg ◽  
Janek Gröhl ◽  
Kris Dreher ◽  
Jan-Hinrich Nölke ◽  
...  

Abstract Purpose Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as vessel topology and tissue oxygenation. While this capacity makes PAT a promising modality for the diagnosis, treatment, and follow-up of various diseases, a current drawback is the limited field of view provided by the conventionally applied 2D probes. Methods In this paper, we present a novel approach to 3D reconstruction of PAT data (Tattoo tomography) that does not require an external tracking system and can smoothly be integrated into clinical workflows. It is based on an optical pattern placed on the region of interest prior to image acquisition. This pattern is designed in a way that a single tomographic image of it enables the recovery of the probe pose relative to the coordinate system of the pattern, which serves as a global coordinate system for image compounding. Results To investigate the feasibility of Tattoo tomography, we assessed the quality of 3D image reconstruction with experimental phantom data and in vivo forearm data. The results obtained with our prototype indicate that the Tattoo method enables the accurate and precise 3D reconstruction of PAT data and may be better suited for this task than the baseline method using optical tracking. Conclusions In contrast to previous approaches to 3D ultrasound (US) or PAT reconstruction, the Tattoo approach neither requires complex external hardware nor training data acquired for a specific application. It could thus become a valuable tool for clinical freehand PAT.

2021 ◽  
Vol 11 (9) ◽  
pp. 3947
Author(s):  
Marco Farronato ◽  
Gianluca M. Tartaglia ◽  
Cinzia Maspero ◽  
Luigi M. Gallo ◽  
Vera Colombo

Clinical use of portable optical tracking system in dentistry could improve the analysis of mandibular movements for diagnostic and therapeutic purposes. A new workflow for the acquisition of mandibular kinematics was developed. Reproducibility of measurements was tested in vitro and intra- and inter-rater repeatability were assessed in vivo in healthy volunteers. Prescribed repeated movements (n = 10) in three perpendicular directions of the tracking-device coordinate system were performed. Measurement error and coefficient of variation (CV) among repetitions were determined. Mandibular kinematics of maximum opening, left and right laterality, protrusion and retrusion of five healthy subjects were recorded in separate sessions by three different operators. Obtained records were blindly examined by three observers. Intraclass correlation coefficient (ICC) was calculated to estimate inter-rater and intra-rater reliability. Maximum in vitro measurement error was 0.54 mm and CV = 0.02. Overall, excellent intra-rater reliability (ICC > 0.90) for each variable, general excellent intra-rater reliability (ICC = 1.00) for all variables, and good reliability (ICC > 0.75) for inter-rater tests were obtained. A lower score was obtained for retrusion with “moderate reliability” (ICC = 0.557) in the inter-rater tests. Excellent repeatability and reliability in optical tracking of primary movements were observed using the tested portable tracking device and the developed workflow.


2018 ◽  
Vol 12 (1) ◽  
pp. 586-595 ◽  
Author(s):  
Abbas Shokri ◽  
Mohammad Reza Jamalpour ◽  
Amir Eskandarloo ◽  
Mostafa Godiny ◽  
Payam Amini ◽  
...  

Introduction: Cortical bone is an important anatomical structure and its thickness needs to be determined prior to many dental procedures to ensure treatment success. Imaging modalities are necessarily used in dentistry for treatment planning and dental procedures. Three-dimensional image reconstruction not only provides visual information but also enables accurate measurement of anatomical structures; thus, it is necessarily required for maxillofacial examination and in case of skeletal problems in this region. Aims: This study aimed to assess the ability of three Cone Beam Computed Tomography (CBCT) systems including Cranex 3D, NewTom 3G and 3D Promax for Three-Dimensional (3D) image reconstruction of the cortical plate with variable thicknesses. Methods: Depending on the cortical bone thickness, samples were evaluated in three groups of ≤ 0. 5 mm, 0.6 -1 mm and 1.1-1.5 mm cortical bone thickness. The CBCT scans were obtained from each sample using three systems, their respective FOVs, and 3D scans were reconstructed using their software programs. Two observers viewed the images twice with a two-week interval. The ability of each system in the 3D reconstruction of different thicknesses of cortical bone was determined based on its visualization on the scans. The data were analyzed using SPSS and Kappa test. Results: The three systems showed the greatest difference in the 3D reconstruction of cortical bone with < 0.5 mm thickness. Cranex 3D with 4×6 cm2 FOV had the highest and 3D Promax with 8×8 cm2 FOV had the lowest efficacy for 3D reconstruction of cortical bone. Cranex 3D with 4×6 cm2 and 6×8 cm2 FOVs and NewTom 3G with 5×5 cm2 and 8×5 cm2 FOVs showed significantly higher efficacy for 3D reconstruction of cortical bone with 0.6-1mm thickness while 3D Promax followed by NewTom 3G with 8×8 cm2 FOV had the lowest efficacy for this purpose. Conclusion: Most CBCT systems have high efficacy for 3D image reconstruction of cortical bone with thicknesses over 1 mm while they have poor efficacy for image reconstruction of cortical bone with less than 0.5 mm thickness. Thus, for accurate visualization of anatomical structures on CBCT scans, systems with smaller FOVs and consequently smaller voxel size are preferred.


Author(s):  
Susan M. Moore ◽  
Mary T. Gabriel ◽  
Maribeth Thomas ◽  
Jennifer Zeminski ◽  
Savio L.-Y. Woo ◽  
...  

Knowledge of joint kinematics contributes to the understanding of the function of soft tissue restraints, injury mechanisms, and can be used to evaluate surgical repair techniques. (Tibone, McMahon et al. 1998; Karduna, McClure et al. 2001; Abramowitch, Papageorgiou et al. 2003) Previous studies have measured joint kinematics using a variety of non-invasive methods that include: optical tracking, magnetic tracking, and mechanical linkage systems. (Rudins, Laskowski et al. 1997; Apreleva, Hasselman et al. 1998; Gabriel, Wong et al. 2004) These measurement devices report kinematics of rigid bodies with respect their own global coordinate system. However, it is often useful to understand these kinematics in terms of a coordinate system whose axes coincide with the degrees of freedom of each specific joint (anatomical coordinate systems). Once the kinematics are obtained with respect to the global coordinate system of the measurement device, the joint kinematics can be calculated with respect to anatomical coordinate systems if the relationship between the measurement device and the anatomical coordinate systems are known. Although the accuracy of these kinematic measurement devices is provided by the manufacturer, the effect of their accuracy on joint kinematics reported with respect to anatomical coordinate systems must be determined. (Panjabi, Goel et al. 1982; Crisco, Chen et al. 1994) For example, small errors in orientation of the measurement system could lead to large errors in position for an anatomical coordinate system located at some distance away. As researchers report joint kinematics with respect to the anatomical coordinate systems, understanding the errors produced by one’s measurement device with respect to the anatomical coordinate systems is necessary. Further, a great deal of interest exists for studying knee joint kinematics. (Sakane, Livesay et al. 1999; Lephart, Ferris et al. 2002; Ford, Myer et al. 2003) Within our research center our goal is to collect knee joint kinematics of a cadaver and reproduce them with respect to the anatomical coordinate systems using robotic technology. Therefore, the objective of this study was to determine the effect of the accuracy of three measurement devices (optical tracking device-OptoTrak® 3020, magnetic tracking device-Flock of Birds®, instrumented spatial linkage-EnduraTec Corp.) on knee joint kinematics reported with respect to an anatomical coordinate system.


Author(s):  
Zachary Hargett ◽  
Manuel Gutierrez ◽  
Melinda Harman

Abstract Cadaveric testing is a common approach for verifying mathematical models used in computational modeling work. In the case of a knee joint model for calculating ligament tension during total knee replacement (TKR) motion, model inputs include rigid body motions defined using the Grood-Suntay coordinate system as a spatial linkage between the tibial component orientation relative to the femoral component. Using this approach requires the definition of coordinate systems for each rigid TKR component (i.e. tibial and femoral) based on fiducial points, manual digitization of a point cloud within the experimental setup, and registration of the orientation relative to the relevant bone marker array. The purpose of this study was to compare the variability between two different manual point digitization methods (a hand-held stylus and pivot tool each calibrated in the optical tracking system), using a TKR femoral component in a simulated cadaver limb experimental setup as an example. This was accomplished by verifying the mathematical algorithm used to calculate the coordinate system from the digitized points, quantifying the variability of the manual digitization methods, and discussing how any error could affect the computational model. For the hand-held stylus method, the standard deviation of the origin and, x-, y-, and z-axis calculations were 0.50mm, 1.31 degrees, 0.51 degrees, and 0.62 degrees, respectively. It is important to note that there is an additional error created using the hand-held stylus from required manual digitization of each rigid marker array. This average additional error was 0.54mm for the origin and 1.70, 1.66, and 0.98 degrees for the x-, y-, and z-axes, respectively. For the pivot tool method, the standard deviation was 0.35mm, 0.37 degrees, 1.27 degrees, and 1.24 degrees for the origin, x-, y-, and z-axes, respectively. It is essential to minimize experimental error, as small errors in alignment can substantially alter model outputs. In this study of cadaver simulation of limb motion, the pivot tool is the better option for minimizing error. Careful definition of fiducial points and repeatable manual digitization of the point cloud is critical for meaningful computational models of TKR motion based on cadaver experimental work.


Author(s):  
F. CHERIET ◽  
J. DANSEREAU ◽  
Y. PETIT ◽  
C.-É. AUBIN ◽  
H. LABELLE ◽  
...  

The main objective of this study was to develop a 3D reconstruction technique of the spine and rib cage of idiopathic scoliotic patients using the self-calibration of the imaging system. The proposed approach computes the intrinsic and extrinsic parameters of the radiographic setup with respect to the global coordinate system used at Ste-Justine Hospital. Our approach determines an optimal estimate of the geometrical parameters of the imaging system from a nonlinear minimization of the mean square distance between the observed and analytical projections of a set of matched points identified on a pair of radiographic views. The accuracy of the optimal estimate for the intrinsic parameters was significantly improved when geometric knowledge such as the known length of detectable straight bars is incorporated as a set of equality constraints in the optimization process. Furthermore, in order to retrieve the 3D structure of interest in the global coordinate system, a reference plane including the origin of the global coordinate system is specified. Computer simulations were performed to evaluate the self-calibration procedure and to determine the minimum knowledge required to obtain an accurate 3D reconstruction for clinical applications. An in vitro validation on real images of a dry cadaveric human spine showed that the method is feasible and reaches the expected accuracy.


Author(s):  
Santosh Bhattacharyya

Three dimensional microscopic structures play an important role in the understanding of various biological and physiological phenomena. Structural details of neurons, such as the density, caliber and volumes of dendrites, are important in understanding physiological and pathological functioning of nervous systems. Even so, many of the widely used stains in biology and neurophysiology are absorbing stains, such as horseradish peroxidase (HRP), and yet most of the iterative, constrained 3D optical image reconstruction research has concentrated on fluorescence microscopy. It is clear that iterative, constrained 3D image reconstruction methodologies are needed for transmitted light brightfield (TLB) imaging as well. One of the difficulties in doing so, in the past, has been in determining the point spread function of the system.We have been developing several variations of iterative, constrained image reconstruction algorithms for TLB imaging. Some of our early testing with one of them was reported previously. These algorithms are based on a linearized model of TLB imaging.


2013 ◽  
Vol 50 (10) ◽  
pp. 840-844
Author(s):  
Yukiya INOUE ◽  
Mayumi KIHARA ◽  
Junko YOSHIMURA ◽  
Naoki YOSHIDA ◽  
Kenji MATSUMOTO ◽  
...  

2020 ◽  
Vol 962 (8) ◽  
pp. 24-37
Author(s):  
V.E. Tereshchenko

The article suggests a technique for relation global kinematic reference system and local static realization of global reference system by regional continuously operated reference stations (CORS) network. On the example of regional CORS network located in the Novosibirsk Region (CORS NSO) the relation parameters of the global reference system WGS-84 and its local static realization by CORS NSO network at the epoch of fixing stations coordinates in catalog are calculated. With the realization of this technique, the main parameters to be determined are the speed of displacement one system center relativly to another and the speeds of rotation the coordinate axes of one system relatively to another, since the time evolution of most stations in the Russian Federation is not currently provided. The article shows the scale factor for relation determination of coordinate systems is not always necessary to consider. The technique described in the article also allows detecting the errors in determining the coordinates of CORS network in global coordinate system and compensate for them. A systematic error of determining and fixing the CORS NSO coordinates in global coordinate system was detected. It is noted that the main part of the error falls on the altitude component and reaches 12 cm. The proposed technique creates conditions for practical use of the advanced method Precise Point Positioning (PPP) in some regions of the Russian Federation. Also the technique will ensure consistent PPP method results with the results of the most commonly used in the Russian Federation other post-processing methods of high-precision positioning.


2021 ◽  
pp. 136943322098663
Author(s):  
Yi-Qun Tang ◽  
Wen-Feng Chen ◽  
Yao-Peng Liu ◽  
Siu-Lai Chan

Conventional co-rotational formulations for geometrically nonlinear analysis are based on the assumption that the finite element is only subjected to nodal loads and as a result, they are not accurate for the elements under distributed member loads. The magnitude and direction of member loads are treated as constant in the global coordinate system, but they are essentially varying in the local coordinate system for the element undergoing a large rigid body rotation, leading to the change of nodal moments at element ends. Thus, there is a need to improve the co-rotational formulations to allow for the effect. This paper proposes a new consistent co-rotational formulation for both Euler-Bernoulli and Timoshenko two-dimensional beam-column elements subjected to distributed member loads. It is found that the equivalent nodal moments are affected by the element geometric change and consequently contribute to a part of geometric stiffness matrix. From this study, the results of both eigenvalue buckling and second-order direct analyses will be significantly improved. Several examples are used to verify the proposed formulation with comparison of the traditional method, which demonstrate the accuracy and reliability of the proposed method in buckling analysis of frame structures under distributed member loads using a single element per member.


Sign in / Sign up

Export Citation Format

Share Document