scholarly journals The Effects of One-Anastomosis Gastric Bypass on Fatty Acids in the Serum of Patients with Morbid Obesity

2021 ◽  
Author(s):  
Alicja Pakiet ◽  
Łukasz P Haliński ◽  
Olga Rostkowska ◽  
Łukasz Kaska ◽  
Monika Proczko-Stepaniak ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Fatty Acids ◽  
Morbid Obesity ◽  
Gastric Bypass ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
One Anastomosis Gastric Bypass ◽  
Fatty Acid Profiles ◽  
Serum Fatty Acid ◽  
Branched Chain

Abstract Purpose Obesity is associated with alterations in serum fatty acid profiles. One-anastomosis gastric bypass is a type of bariatric surgery used in the treatment of morbid obesity. The aim of this study was to establish if, between 6 and 9 months after this procedure, the fatty acid composition in the serum of patients normalizes to values similar to the healthy, lean population. Materials/Methods The study included 46 patients that underwent surgical treatment for obesity with one-anastomosis gastric bypass. The serum fatty acid composition was determined using gas chromatography-mass spectrometry. Principal component analysis was conducted to detect the differences between fatty acid profiles in patients pre- and post-surgery, and in 29 control nonobese subjects. Results Patients with morbid obesity were characterized by lowered levels of beneficial odd- and branched-chain fatty acids and polyunsaturated fatty acids. While the odd- and branched-chain fatty acid amounts normalized 6–9 months after bariatric treatment, the polyunsaturated fatty acid levels did not. Moreover, the total fatty acid profiles of patients pre- and post-bariatric surgery were still markedly different than those of lean, healthy controls. Conclusion Following one-anastomosis gastric bypass, there are some beneficial changes in serum fatty acids in treated patients, possibly due to weight loss and dietary regimen changes. However, they may be insufficient to restore the proper levels of other fatty acids, which may need to be additionally supplemented. Graphical abstract

scholarly journals Short-Term Effect of One-Anastomosis Gastric Bypass on Essential Fatty Acids in the Serum of Obese Patients

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 187
Author(s):  
Adriana Mika ◽  
Maciej Wilczynski ◽  
Alicja Pakiet ◽  
Lukasz Kaska ◽  
Monika Proczko-Stepaniak ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Gastric Bypass ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
One Anastomosis Gastric Bypass ◽  
Obese Patients ◽  
Short Term ◽  
Serum Fatty Acid ◽  
Serum Fatty Acid Composition

One-anastomosis gastric bypass is a promising type of bariatric surgery, but it may lead to a deficiency in important nutrients, such as fatty acids. The short-term effects of one-anastomosis gastric bypass on serum fatty acids have not been studied thus far. Therefore, the aim of this study was to determine the effect of one-anastomosis gastric bypass on serum fatty acid composition two weeks after surgery. This study included 38 patients who underwent one-anastomosis gastric bypass as surgical treatment for morbid obesity. Serum fatty acid composition was analyzed before and two weeks after surgery using gas chromatography–mass spectrometry. We observed a decrease in essential polyunsaturated fatty acids (p < 0.001 for linolenic acid and p < 0.001 for linoleic acid) and odd-chain fatty acids (p = 0.004) in the serum of obese patients shortly after a one-anastomosis gastric bypass. Considering the benefits of the aforementioned fatty acids for human health, the implementation of a fatty-acid-rich diet or the use of supplementation may be recommended for patients immediately after one-anastomosis gastric bypass.

PSXV-25 Effects of multiple grass-fed and grain-fed beef systems on meat fatty acid composition

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 324-324
Author(s):  
Sarah C Klopatek ◽  
Xiang Yang ◽  
James W Oltjen ◽  
Payam Vahmani
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Fatty Acid Profiles ◽  
Conjugated Linoleic Acids ◽  
Branched Chain Fatty Acids ◽  
Short Period ◽  
Bioactive Fatty Acids ◽  
Branched Chain

Abstract Retail sales of labeled fresh grass-fed beef in the U.S. have grown from $17 million in 2012 to $272 million in 2016. The objective of present study was to investigate the effect of four typical grass-fed and conventional beef systems raised in the western United States on beef fatty-acid composition. Treatments included: 1) steers stocked on pasture then finished in a feedyard (CON), 2) steers grass-fed for 20 months (GF20), 3) steers grass-fed for 20 months with a 45-day grain finish (GR45), and 4) steers grass-fed for 25 months (GF25). Fatty acids were analyzed with GC using a 100 m CPSil 88 capillary column. All statistical analyses were performed using a GLM procedure in R. Saturated fatty acid (SFA) concentrations were significantly different across treatments (P &lt; 0.05) with GR45 having the lowest SFA of 43% and GF25 having the highest SFA at 46%. Cis-monounsaturated fatty acid (c-MUFA) particularly oleic acid, which is known as a heart healthy fatty acids, were highest for CON at 44% and lowest for GF20 at 37% (P &lt; 0.05). Conjugated linoleic acids (CLA) were significantly lower for the grain-fed treatments (0.54 CON and 0.63 GR45; P &lt; 0.05) compared to grass-fed treatments (0.93 GF20 and 0.86 GF25; P &lt; 0.05). The grass-fed treatments were higher in n-3 PUFA (3.67 GF20 and 2.29 GF25) than CON (0.79; P &lt; 0.05), however feeding grain for a short period of time did not decrease n-3 PUFA concentrations to the CON level (GF45 2.51; P &lt; 0.05). In conclusion, our findings show that beef from grain-fed beef management systems is higher in c-MUFA, while grass-fed is significantly higher in bioactive fatty acids including CLA and branched chain fatty acids. Additional studies are needed to determine if fatty acid profiles between grass-fed and grain-fed beef would result in different health outcomes for the consumers.

scholarly journals Characterization of planktonic and biofilm fatty acid profiles and evaluation of their trophic transfer potential to Hyalella Azteca

2021 ◽  
Author(s):  
Jerry Chien-Yao Chao
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Bacterial Species ◽  
Saturated Fatty Acids ◽  
Hyalella Azteca ◽  
Fatty Acid Profiles ◽  
Fa Composition ◽  
Branched Chain ◽  
Transfer Potential

Fatty acid (FA) composition between biofilms and batch planktonic cultures were compared for two bacterial species Pseudomonas aeruginosa and Staphylococcus aureaus. Biofilm cultures exhibited decrease in saturated fatty acids (SAFA) that potentially conform to a more fluidic biophysical membrane property. The amount of FA in the biofilms' extracellular polymeric substance was not sufficient to consider it having a major contribution to the observed differences between biofilms and batch planktonic cultures. While biofilm grazing by the amphipod Hyalella azteca was evident, only certain bacteria-specific FA appeared to have the potential to be retained (odd-number SAFA and branched-chain FA). H. azteca with diet strictly consisted of bacteria biofilms did not demonstrate significant changes in their nutritional condition in terms of ω-3 and ω-6 polyunsaturated fatty acids (PUFA): combined with the results from fasting trials, H. azteca appears to have the capacity to retain ω-3 and ω-6 PUFAs up to 10 days.

0253 The effect of frequency of supplementing rumen protected unsaturated fatty acids on blood serum fatty acid profiles in beef heifers and lactating cows

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 120-121
Author(s):  
E. K. Cook ◽  
M. E. Garcia-Ascolani ◽  
R. E. Ricks ◽  
S. K. Duckett ◽  
N. DiLorenzo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Blood Serum ◽  
Unsaturated Fatty Acids ◽  
Fatty Acid Profiles ◽  
Beef Heifers ◽  
Serum Fatty Acid ◽  
Lactating Cows

The effect of frequency of supplementing rumen-protected unsaturated fatty acids on blood serum fatty acid profiles in beef heifers and lactating cows1

2017 ◽  
Vol 95 (7) ◽  
pp. 2977-2985
Author(s):  
E. K. Cook ◽  
M. E. Garcia-Ascolani ◽  
R. E. Ricks ◽  
S. K. Duckett ◽  
G. C. Lamb ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Blood Serum ◽  
Unsaturated Fatty Acids ◽  
Fatty Acid Profiles ◽  
Beef Heifers ◽  
Serum Fatty Acid

scholarly journals Fatty Acid Composition of Caprine Milk: Major, Branched-Chain, and Trans Fatty Acids

1999 ◽  
Vol 82 (5) ◽  
pp. 878-884 ◽  
Author(s):  
L. Alonso ◽  
J. Fontecha ◽  
L. Lozada ◽  
M.J. Fraga ◽  
M. Juárez
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Trans Fatty Acids ◽  
Caprine Milk ◽  
Branched Chain

The fatty acid composition of lipids of neuronal and glial nuclear fractions isolated from 15-day-old rabbit cerebral cortex

1980 ◽  
Vol 58 (8) ◽  
pp. 620-628 ◽  
Author(s):  
R. Roy Baker ◽  
Huu-Yi Chang
Keyword(s):  
Fatty Acids ◽  
Cerebral Cortex ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Molecular Species ◽  
Similar Pattern ◽  
Phosphatidyl Inositol ◽  
Nuclear Fraction ◽  
Fatty Acid Profiles ◽  
Rabbit Cerebral Cortex

A neuronal nuclear fraction (N1) and a glial nuclear fraction (N2) have been isolated from 15-day-old rabbit cerebral cortex using the Thompson procedure. More than 56% of the homogenate DNA was recovered in the two nuclear fractions, with N1 being the larger by about eightfold. Fractions N1 and N2 had very similar phospholipid distributions, with phosphatidyl-inositol being a larger component than phosphatidylserine. Fatty acid analyses demonstrated that phosphatidylethanolamine and phosphatidylinositol, individually, had similar fatty acid profiles in fractions N1 and N2, and also in nuclear and microsomal fractions derived from homogenates of nerve cell bodies isolated from cerebral cortex of 15-day-old rabbits. In contrast, the nuclear phosphatidylcholines had lower levels of palmitate and higher levels of arachidonate than did microsomal phosphatidylcholines. Molecular species analyses indicated that monoenes (41 mol%), tetraenes (20 mol%), and saturates (13 mol%, composed chiefly of palmitate) were the principal classes of N1 phosphatidylcholines, while the diacyl species of phosphatidylethanolamine of this fraction were characterized by high levels of tetraenes (44 mol%), pentaenes (17 mol%), and hexaenes + polyenes (24 mol%). The neutral glycerides of fraction N1 occurred collectively at a level of 0.05 mol/mol phospholipid. Prominent fatty acids of diacylglycerols included palmitate (31%), oleate (20%), arachidonate (14%), and stéarate (13%). Triacylglycerols showed a similar pattern but with relatively high levels of linoleate (11%), while monoacylglycerols consisted almost entirely of palmitate (33%), stearate (35%), and oleate (24%).

scholarly journals The Combination of Resveratrol and Quercetin Attenuates Metabolic Syndrome in Rats by Modifying the Serum Fatty Acid Composition and by Upregulating SIRT 1 and SIRT 2 Expression in White Adipose Tissue

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Ana Elena Peredo-Escárcega ◽  
Verónica Guarner-Lans ◽  
Israel Pérez-Torres ◽  
Sergio Ortega-Ocampo ◽  
Elizabeth Carreón-Torres ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Fatty Acids ◽  
Drinking Water ◽  
Adipose Tissue ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
White Adipose Tissue ◽  
Serum Fatty Acid ◽  
Serum Fatty Acid Composition

Resveratrol (RSV) and quercetin (QRC) modify energy metabolism and reduce cardiovascular risk factors included in the metabolic syndrome (MetS). These natural compounds upregulate and activate sirtuins (SIRTs), a family of NAD-dependent histone deacetylases. We analyzed the effect of two doses of a commercial combination of RSV and QRC on serum fatty acid composition and their regulation of SIRTs 1–3 and PPAR-γexpression in white adipose tissue. MetS was induced in Wistar rats by adding 30% sucrose to drinking water for five months. Rats were divided into control and two groups receiving the two different doses of RSV and QRC in drinking water daily for 4 weeks following the 5 months of sucrose treatment. Commercial kits were used to determine serum parameters and the expressions of SIRTs in WAT were analysed by western blot. In MetS rats body mass, central adiposity, insulin, triglycerides, non-HDL-C, leptin, adiponectin, monounsaturated fatty acids (MUFAs), and nonesterified fatty acids (NEFAs) were increased, while polyunsaturated fatty acids (PUFAs) and HDL-C were decreased. SIRT 1 and SIRT 2 were downregulated, while PPAR-γwas increased. RSV + QRC administration improved the serum health parameters modified by MetS and upregulate SIRT 1 and SIRT 2 expression in white abdominal tissue in MetS animals.

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