scholarly journals Trends in Metal-Based Composite Biomaterials for Hard Tissue Applications

JOM ◽  
2021 ◽  
Author(s):  
Gargi Shankar Nayak ◽  
Adele Carradò ◽  
Patrick Masson ◽  
Geneviève Pourroy ◽  
Flavien Mouillard ◽  
...  

AbstractThe world of biomaterials has been continuously evolving. Where in the past only mono-material implants were used, the growth in technology and collaboration between researchers from different sectors has led to a tremendous improvement in implant industry. Nowadays, composite materials are one of the leading research areas for biomedical applications. When we look toward hard tissue applications, metal-based composites seem to be desirable candidates. Metals provide the mechanical and physical properties needed for load-bearing applications, which when merged with beneficial properties of bioceramics/polymers can help in the creation of remarkable bioactive as well biodegradable implants. Keeping this in mind, this review will focus on various production routes of metal-based composite materials for hard tissue applications. Where possible, the pros and cons of the techniques have been provided.

Metals ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1831
Author(s):  
Robert Bidulsky ◽  
Federico Simone Gobber ◽  
Jana Bidulska ◽  
Marta Ceroni ◽  
Tibor Kvackaj ◽  
...  

In the last years, functionalized powders are becoming of increasing interest in additive manufacturing (particularly in laser powder bed fusion processing, L-PBF), due to their improved flowability and enhanced processability, particularly in terms of laser absorbance. Functionalized powders may also provide higher final mechanical or physical properties in the manufactured parts, like an increased hardness, a higher tensile strength, and density levels close to theoretical. Coatings represent a possible interesting approach for powders’ functionalizing. Different coating methods have been studied in the past years, either mechanical or non-mechanical. This work aims to present an overview of the currently obtained coated powders, analyzing in detail the processes adopted for their production, the processability of the coated systems, and the mechanical and physical properties of the final parts obtained by using L-PBF for the powders processing.


Author(s):  
Michael Hochberg

The world of publishing has changed considerably over the past 20 years. Who can view published material, who pays for content and alternative models to classic peer reviewed journals are all important in considering where to publish your work. This chapter presents choices in publication venue and discusses the pros and cons of each.


Polymers ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 830 ◽  
Author(s):  
DaeYong Lee ◽  
N. Rejinold ◽  
Seong Jeong ◽  
Yeu-Chun Kim

Stimuli-responsive polypeptides have gained attention because desirable bioactive properties can be easily imparted to them while keeping their biocompatibility and biodegradability intact. In this review, we summarize the most recent advances in various stimuli-responsive polypeptides (pH, reduction, oxidation, glucose, adenosine triphosphate (ATP), and enzyme) over the past five years. Various synthetic strategies exploited for advanced polypeptide-based materials are introduced, and their applicability in biomedical fields is discussed. The recent polypeptides imparted with new stimuli-responsiveness and their novel chemical and physical properties are explained in this review.


2019 ◽  
Vol 20 (12) ◽  
pp. 1255-1263 ◽  
Author(s):  
Vishnu Sankar Sivasankarapillai ◽  
Jobin Jose ◽  
Muhammad Salman Shanavas ◽  
Akash Marathakam ◽  
Md. Sahab Uddin ◽  
...  

Nanotechnology has emerged as one of the leading research areas involving nanoscale manipulation of atoms and molecules. During the past decade, the growth of nanotechnology has been one of the most important developments that have taken place in the biomedical field. The new generation nanomaterials like Quantum dots are gaining much importance. Also, there is a growing interest in the development of nano-theranostics platforms in medical diagnostics, biomedical imaging, drug delivery, etc. Quantum dots are also known as nanoscale semiconductor crystals, with unique electronic and optical properties. Recently, silicon quantum dots are being studied extensively due to their less-toxic, inert nature and ease of surface modification. The silicon quantum dots (2-10nm) are comparatively stable, having optical properties of silicon nanocrystals. This review focuses on silicon quantum dots and their various biomedical applications like drug delivery regenerative medicine and tissue engineering. Also, the processes involved in their modification for various biomedical applications along with future aspects are discussed.


2019 ◽  
Vol 2019 ◽  
pp. 1-16 ◽  
Author(s):  
Fakhara Sabir ◽  
Muhammad Imran Asad ◽  
Maimoona Qindeel ◽  
Iqra Afzal ◽  
Muhammad Junaid Dar ◽  
...  

Nanomaterials have found extensive biomedical applications in the past few years because of their small size, low molecular weight, larger surface area, enhanced biological, and chemical reactivity. Among these nanomaterials, nanogels (NGs) are promising drug delivery systems and are composed of cross-linked polymeric nanoparticles ranging from 100 to 200 nm. NGs represent an innovative zone of research with speedy developments taking place on a daily basis. An incredible amount of focus is placed on the fabrication of NGs with novel polymers to achieve better control over the drug release. This review article covers a number of aspects of NGs including their types, associated pros and cons, and methods of preparation along with technical and economical superiority and therapeutic efficacy over each other. The last part of review summarizes the applications of NGs in the drug delivery and treatment of various diseases including brain disease, cardiovascular diseases, oxidative stress, diabetes, cancer therapy, tissue engineering, gene therapy, inflammatory disorders, pain management, ophthalmic and autoimmune diseases, and their future challenges. NGs appear to be an outstanding nominee for drug delivery systems, and further study is required to explore their interactions at the cellular and molecular levels.


e-Polymers ◽  
2019 ◽  
Vol 19 (1) ◽  
pp. 385-410 ◽  
Author(s):  
Tejas V. Shah ◽  
Dilip V. Vasava

AbstractOver the past two decades, biodegradable polymers (BPs) have been widely used in biomedical applications such as drug carrier, gene delivery, tissue engineering, diagnosis, medical devices, and antibacterial/antifouling biomaterials. This can be attributed to numerous factors such as chemical, mechanical and physiochemical properties of BPs, their improved processibility, functionality and sensitivity towards stimuli. The present review intended to highlight main results of research on advances and improvements in terms of synthesis, physical properties, stimuli response, and/or applicability of biodegradable plastics (BPs) during last two decades, and its biomedical applications. Recent literature relevant to this study has been cited and their developing trends and challenges of BPs have also been discussed.


Author(s):  
Saad A. Al-Jebory ◽  
M.H. Al-Maamori

Composite materials consist of merging two materials or more are different in mechanical and physical properties,The aim of research is to study the effect of changing in the rainforcment percentage by fly ash in mechanical Properties ,for composite material consist of NBR rubber rainforced by carbon black (40pphr) and fly ash (0,15,18,20,23,26,30 pphr), which included tensile strength,modulus,elongation, hardness,tear,rasillince,after rainforced NBR rubber with different weight percentage from fly ash and study the effect on above Properties as illustrated in the diagrams


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