scholarly journals Clinical management of patients with genetic obesity during COVID-19 pandemic: position paper of the ESE Growth & Genetic Obesity COVID-19 Study Group and Rare Endo-ERN main thematic group on Growth and Obesity

Endocrine ◽  
2021 ◽  
Author(s):  
Cornelis Jan De Groot ◽  
Christine Poitou Bernert ◽  
Muriel Coupaye ◽  
Karine Clement ◽  
Stavroula A. Paschou ◽  
...  
Keyword(s):  
Healthy Lifestyle ◽  
Position Paper ◽  
Study Group ◽  
Obesity Management ◽  
Genetic Obesity ◽  
Syndromic Obesity ◽  
Prevention And Treatment ◽  
Medication Dose ◽  
Inflammatory Phenotype ◽  
Intellectual Deficit

AbstractThis article aims to provide guidance on prevention and treatment of COVID-19 in patients with genetic obesity. Key principals of the management of patients with genetic obesity during COVID-19 pandemic for patients that have contracted COVID-19 are to be aware of: possible adrenal insufficiency (e.g., POMC deficiency, PWS); a more severe course in patients with concomitant immunodeficiency (e.g., LEP and LEPR deficiency), although defective leptin signalling could also be protective against the pro-inflammatory phenotype of COVID-19; disease severity being masked by insufficient awareness of symptoms in syndromic obesity patients with intellectual deficit (in particular PWS); to adjust medication dose to increased body size, preferably use dosing in m2; the high risk of malnutrition in patients with Sars-Cov2 infection, even in case of obesity. Key principals of the obesity management during the pandemic are to strive for optimal obesity management and a healthy lifestyle within the possibilities of the regulations to prevent weight (re)gain and to address anxiety within consultations, since prevalence of anxiety for COVID-19 is underestimated.

Patients’ Awareness Of The Prevention And Treatment Of Colorectal Cancer*

2015 ◽  
Vol 87 (9) ◽  
Author(s):  
Łukasz Dziki ◽  
Anna Puła ◽  
Konrad Stawiski ◽  
Barbara Mudza ◽  
Marcin Włodarczyk ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Treatment Process ◽  
Significant Negative Correlation ◽  
Study Group ◽  
Case Record ◽  
High Incidence ◽  
Prevention And Treatment ◽  
Major Factors ◽  
Medical University

Abstractwas to assess patients’ awareness of the prevention and treatment of colorectal cancer.Patients diagnosed with colorectal cancer, hospitalised at the Department of General and Colorectal Surgery of the Medical University in Łódź during the period from January 2015 to April 2015, were asked to complete a questionnaire concerning their families’ medical case record, factors predisposing them to the development of colorectal cancer, the tests applied in diagnostics, and the treatment process. The questionnaire comprised 42 closed-ended questions with one correct answer. A statistical analysis of all answers was carried out.The study group consisted of 30 men and 20 women aged 27–94 years old. A strong, statistically significant negative correlation between a patient’s age and his/her awareness of the prevention and treatment of colorectal cancer was noted (p<0.001; r= −0.51). The study demonstrated a statistically significant relationship between the occurrence of neoplasms in a patient’s family (p=0.009) or, more specifically, the occurrence of colorectal cancer (p=0.008), and the awareness of the prevention programme. The women’s group was characterised by statistically significantly greater awareness of colonoscopy as a screening examination (p=0.004).Patients need more information on colorectal cancer, its risk factors, prevention, the treatment process, and postoperative care. Lack of awareness of the colorectal cancer issue can be one of the major factors contributing to the high incidence of this disease.

scholarly journals Case Report: Liraglutide for Weight Management in Beckwith-Wiedemann Syndromic Obesity

2021 ◽  
Vol 12 ◽  
Author(s):  
Marina Caputo ◽  
Tommaso Daffara ◽  
Simonetta Bellone ◽  
Valentina Mancioppi ◽  
Paolo Marzullo ◽  
...  
Keyword(s):  
Kinase Inhibitor ◽  
Sleep Apnea Syndrome ◽  
Genetic Obesity ◽  
Cyclin Dependent Kinase Inhibitor ◽  
Imprinting Disorder ◽  
Melanocortin 4 Receptor ◽  
First Case ◽  
Syndromic Obesity ◽  
Obstructive Sleep ◽  
Clinical Conditions

Genetic obesity, including syndromic and non-syndromic forms, represents a minority of cases compared to essential obesity but gene dysregulations lead to complex clinical conditions that make their management particularly difficult. Among them, Beckwith-Wiedemann syndrome (BWS) is a multisystem human genomic imprinting disorder characterized by overgrowth. We describe the first case of liraglutide treatment in an 18-year-old boy patient affected by BWS complicated by macroglossia, cryptorchidism, nephroblastoma, organomegaly, microscopic lymphocytic colitis, pharmacologically treated arterial hypertension, obesity, and obstructive sleep apnea syndrome. He presented a normal cognitive development. Body mass index at the time of first transition visit in the adult endocrinology department at the age of 18-years-old was 40.6 kg/m2 without glucose metabolism impairment. Lifestyle interventions failed because of poor compliance. During 20 months of 3.0 mg liraglutide treatment, a weight loss of 19 kg (−13.3%) and BMI reduction of 6.8 points were registered without side effects. To date, liraglutide treatment was effective on obesity in 7 subjects with Prader Willy Syndrome and 14 with melanocortin-4 receptor mutations. The efficacy of liraglutide in BWS could be related to a crosstalk among glucagon-like peptide (GLP)-1 system, mechanisms related to the cyclin-dependent kinase inhibitor 1C (CDKN1C), and dopamine mesolimbic circuit. Clinical trials aiming at a tailored medicine in genetic obesity are needed.

scholarly journals Quality of Life of Patients with Arterial Hypertension

Medicina ◽  
2020 ◽  
Vol 56 (9) ◽  
pp. 459
Author(s):  
Katarzyna Snarska ◽  
Monika Chorąży ◽  
Michał Szczepański ◽  
Marzena Wojewódzka-Żelezniakowicz ◽  
Jerzy Robert Ładny
Keyword(s):  
Quality Of Life ◽  
Healthy Lifestyle ◽  
Statistical Significance ◽  
Study Group ◽  
Modifiable Risk Factors ◽  
Factors Affecting ◽  
Social Sphere ◽  
Medium Level ◽  
The City

Symptoms of hypertension with accompanying complications result in a significant reduction in patients’ quality of life. Effective conduct of prescribed pharmacotherapy supported by a healthy lifestyle allows to achieve satisfactory effects of treatment, which translates into an improvement in the quality of life of patients. The aim of the work was to determine the quality of life of patients with hypertension and the factors affecting it. The study included 100 people with hypertension, who are patients of the department of internal diseases of the hospital in Hajnówka during the period 1.6.2019–1.12.2019. The questionnaire survey, the standardized WHO Quality of Life (WHOQOL)-BREF scale and the Barthel scale were the research tools. The probability p < 0.05 was assumed as the level of statistical significance. The study group consisted of subjects between 30–89 years old. The majority were men and those living in the city. The average BMI (body mass index) of the subjects was 28.4 kg/m2. The duration of the disease among those surveyed was on average 7 ± 6.34 years. The highest-rated area of quality of life was the physical field and the lowest social sphere according to the WHOQOL-BREF questionnaire. Patients with hypertension have determined their quality of life at a good or medium level in the physical, psychological, social, and environmental sphere. There are many factors that improve quality of life in all areas. These include following the recommendations on modifiable risk factors.

scholarly journals Maternal Obesity Management Using Mobile Technology: A Feasibility Study to Evaluate a Text Messaging Based Complex Intervention during Pregnancy

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Hora Soltani ◽  
Alexandra M. S. Duxbury ◽  
Madelynne A. Arden ◽  
Andy Dearden ◽  
Penny J. Furness ◽  
...  
Keyword(s):  
Mobile Technology ◽  
Complex Intervention ◽  
Text Messaging ◽  
Maternal Obesity ◽  
Comparison Group ◽  
Healthy Lifestyle ◽  
Negative Impact ◽  
Text Messages ◽  
Obese Women ◽  
Obesity Management

Background. Maternal obesity and excessive gestational weight gain (GWG) are on the rise with negative impact on pregnancy and birth outcomes. Research into managing GWG using accessible technology is limited. The maternal obesity management using mobile technology (MOMTech) study aimed at evaluating the feasibility of text messaging based complex intervention designed to support obese women (BMI ≥ 30) with healthier lifestyles and limit GWG.Methods. Participants received two daily text messages, supported by four appointments with healthy lifestyle midwife, diet and activity goal setting, and self-monitoring diaries. The comparison group were obese mothers who declined to participate but consented for their routinely collected data to be used for comparison. Postnatal interviews and focus groups with participants and the comparison group explored the intervention’s acceptability and suggested improvements.Results. Fourteen women completed the study which did not allow statistical analyses. However, participants had lower mean GWG than the comparison group (6.65 kg versus 9.74 kg) and few (28% versus 50%) exceeded the Institute of Medicine’s upper limit of 9 kg GWG for obese women.Conclusions. MOMTech was feasible within clinical setting and acceptable intervention to support women to limit GWG. Before further trials, slight modifications are planned to recruitment, text messages, and the logistics of consultation visits.

Chosen marketing and public relations techniques used by Ewa Chodakowska in promoting a healthy lifestyle - study on opinions of respondents on the Ewa Chodakowska method

2016 ◽  
Vol 6 (2) ◽  
pp. 84-91
Author(s):  
A. Tyrańska-Fobke ◽  
A. Konieczna ◽  
A. Kuich ◽  
A. Janaszczyk ◽  
K. Leoniuk
Keyword(s):  
Physical Activity ◽  
Public Relations ◽  
Marketing Strategy ◽  
Obesity Prevention ◽  
Healthy Lifestyle ◽  
Study Group ◽  
Place Of Residence ◽  
Physically Active ◽  
Internet Users ◽  
Chi Squared

Purpose: To assess the opinions of people, using, or familiar with Chodakowska’s method, on her marketing strategy and public relations. Materials and methods: The research was conducted between the 31st of March and the 4th of April 2014. A questionnaire, consisting of 31 questions was created and uploaded at website. All internet users, interested in Chodakowska’s method, were able to take part in the research. The study group consisted of 1005 respondents. Results; The vast majority of respondents familiar in any way with Chodakowska used her workout programs. The Chi-squared test indicated statistically significant dependency between the place of residence and using Chodakowska’s workout programs. Among the ways of getting to know Chodakowska’s workout programs, friends proved to be the most common and the official Facebook fan page took second place. Among all respondents, who use the workout programs have never used any program, before they learned about Chodakowska and her method. The majority of respondents declare that the popularity of Chodakowska is due to the free of charge YouTube movies, then the regularly updated Facebook fan page, building a community of physically active people. Conclusions: The results of the study it is possible to state that using a customized approach and creating a positive image in relations with society can be adopted in promoting physical activity and a healthy diet. In addition, one can state that when developing future obesity prevention campaigns, the achievements and experience of Chodakowska should be taken into account.

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