Antenatal exposure to doxylamine succinate and dicyclomine hydrochloride (Bendectin) in relation to congenital malformations, perinatal mortality rate, birth weight, and intelligence quotient score

AbstractThe influence of maternal age and congenital malformations on perinatal mortality in twins in Australia from 1973 to 1980, is described. Stillbirths and neonatal deaths in twins fell with advancing maternal age. For teenage mothers, the twin perinatal mortality rate was 127.15/1,000. The sex ratio in twins is closer to unity than in singletons. Perinatal mortality due to malformation fell as maternal age increased up to 35 years. The role of zygosity and the distribution of birth weight with maternal age are discussed.

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Investigation of Regional Perinatal Mortality Rate and Causes in Jeddah, Saudi Arabia

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl4.4285 ◽

2020 ◽

Vol 11 (SPL4) ◽

pp. 1244-1250

Author(s):

Nasser Hadal Alotaibi ◽

Abdulaziz I. Alzarea ◽

Ahmed Hassan ◽

Mohammed Gamal ◽

Shakeel Iqubal S M ◽

...

Keyword(s):

Saudi Arabia ◽

Birth Weight ◽

Mortality Rate ◽

Low Birth Weight ◽

Perinatal Mortality ◽

Perinatal Death ◽

Respiratory Arrest ◽

Perinatal Mortality Rate ◽

Tertiary Hospitals ◽

Preconception Counselling

The primary purpose of this study is to recognize the perinatal mortality rate and the vital causes of perinatal mortality to ascertain the significant maternal elements for a safe birth. A retrospective study was carried out in three large tertiary hospitals in Jeddah, Saudi Arabia, in the period from January 1, 2010, through December 31, 2015. All perinatal deaths happening during that time were analyzed. During the six-year review period, a total of 280 infant deaths were recorded with a perinatal mortality rate (PMR) of 6.6 per 1000 births. The principal causes of death among the deceased were low birth weight (LBW) (87%), lethal congenital malformation (CM) (4%), sepsis (3%), and respiratory arrest (3%). The PMR was high in 2010 at 6.8, while it declined to 6.4 at the end of the period studied. The average PMR recorded in this study was 6.6 per 1000 births. This study showed that low birth weight is the main reason for prenatal mortality, although the PMR did decline by the end of the period. A decrease in the perinatal death rate is viable when all females start to attend preconception counselling and are present at antenatal health centres.

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USE OF REFINED PERINATAL MORTALITY RATE TRENDS TO EVALUATE THE EFFECT OF A CONFIDENTIAL INQUIRY

The Lancet ◽

10.1016/s0140-6736(85)91509-0 ◽

1985 ◽

Vol 326 (8448) ◽

pp. 197-199 ◽

Cited By ~ 9

Author(s):

Joyce Thomas ◽

Joan Edwards ◽

Peter Bowen-Simpkins ◽

DewiR. Evans ◽

StuartP. Jenkins ◽

...

Keyword(s):

Mortality Rate ◽

Perinatal Mortality ◽

Perinatal Mortality Rate

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Risk factors for perinatal mortality: a case control study from Thiruvananthapuram, Kerala, India

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20172330 ◽

2017 ◽

Vol 6 (6) ◽

pp. 2452 ◽

Cited By ~ 1

Author(s):

Mayadevi Brahmanandan ◽

Lekshmi Murukesan ◽

Bindu Nambisan ◽

Shaila Salmabeevi

Keyword(s):

Risk Factors ◽

Mortality Rate ◽

Perinatal Mortality ◽

Case Control Study ◽

Gestational Hypertension ◽

Significant Risk ◽

Case Control ◽

Maternal Risk ◽

Perinatal Mortality Rate ◽

Control Study

Background: The greatest risks to life are in its very beginning. Although a good start in life begins well before birth, it is just before, during, and in the very first hours and days after birth that life is most at risk. This prospective case control study was designed on maternal risk factors for perinatal mortality.Methods: This was a case control study conducted in the Department of Obstetrics and Gynecology and Department of Paediatrics, Medical College Trivandrum for one year period in 2004-2005. The cases were all the fresh and macerated still births and early neonatal death cases during the study period. The controls were chosen as the next delivery entry in the OR register.Results: During this period, the total number of deliveries was 14,796 and there were 431 perinatal deaths. The perinatal mortality rate was 29.12. This was much higher compared to Kerala’s perinatal mortality rate of 10, the reason being that the study is conducted in a tertiary referral hospital with one of the best new born care nurseries and a large number of referrals. The most significant risk factors for perinatal mortality were low socio-economic status, referrals, late registration, prematurity, low birth weight, intra-uterine growth restriction, maternal diseases like gestational hypertension and gestational diabetes and intrapartum complications like abruption.Conclusions: Perinatal mortality rate serves as the most sensitive index of maternal and neonatal care. Good antenatal care and prevention of preterm birth may play a key role in further reduction of PMR.

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Perinatal Mortality Analysis in Espírito Santo, Brazil, 2008 to 2017

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph182111671 ◽

2021 ◽

Vol 18 (21) ◽

pp. 11671

Author(s):

Italla Maria Pinheiro Bezerra ◽

José Lucas Souza Ramos ◽

Micael Colodetti Pianissola ◽

Fernando Adami ◽

João Batista Francalino da Rocha ◽

...

Keyword(s):

Time Series ◽

Information System ◽

Mortality Rate ◽

Perinatal Mortality ◽

Birth Asphyxia ◽

Strong Positive Correlation ◽

Significance Level ◽

Espírito Santo ◽

Perinatal Mortality Rate ◽

Espirito Santo

This is an ecological and time-series study using secondary data on perinatal mortality and its components from 2008 to 2017 in Espírito Santo, Brazil. The data were collected from the Mortality Information System (SIM) and Live Births Information System (SINASC) of the Unified Health System Informatics Department (DATASUS) in June 2019. The perinatal mortality rate (×1000 total births) was calculated. Time series were constructed from the perinatal mortality rate for the regions and Espírito Santo. To analyze the trend, the Prais–Winsten model was used. From 2008 to 2017 there were 8132 perinatal deaths (4939 fetal and 3193 early neonatal) out of a total of 542,802 births, a perinatal mortality rate of 15.0/1000 total births. The fetal/early neonatal ratio was 1.5:1, with a strong positive correlation early neonatal mortality rate, perinatal mortality rate, r (9) = 0.8893, with a significance level of p = 0.000574. The presence of differences in trends by health region was observed. Risk factors that stood out were as follows: mother’s age ranging between 10 and 19 or 40 and 49 years old, with no education, a gestational age between 22 and 36 weeks, triple and double pregnancy, and a birth weight below 2499 g. Among the causes of death, 49.70% of deaths were concentrated in category of the tenth edition of the International Classification of Diseases, fetuses and newborns affected by maternal factors and complications of pregnancy, labor, and delivery (P00–P04), and 11.03% were in the category of intrauterine hypoxia and birth asphyxia (P20–P21), both related to proper care during pregnancy and childbirth. We observed a slow reduction in the perinatal mortality rate in the state of Espírito Santo from 2008 to 2017.

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Analysis of The Fairness of Child Health Services In China 2010-2019

10.21203/rs.3.rs-468598/v2 ◽

2021 ◽

Author(s):

Ji Wu ◽

Hao-Nan Jin ◽

Yi-Lei Lao ◽

Xian-Guo Qu

Keyword(s):

Mortality Rate ◽

Child Health ◽

Health Service ◽

Health Services ◽

Perinatal Mortality ◽

Child Health Services ◽

Child Health Service ◽

Care Services ◽

Perinatal Mortality Rate ◽

Service Projects

Abstract Background: The imbalance of child health services caused by the huge income gap between urban and rural residents and uncoordinated regional development has become increasingly prominent. This article analyzes the basic situation and equity of child care services in China from 2010 to 2019.Methods: Evaluate the equity of child health services by concentration index.Results: From 2010 to 2019, neonatal visit rate and system management rate of under-three children in Chinese child health service projects showed an upward trend, and the perinatal mortality rate decreased. The perinatal mortality rate is the highest in the western region, and the level of child health services in the central region is lower than the national average, but the gap between regions has gradually decreased. Child health services concentrate in provinces with high economic levels, and the perinatal mortality rate is the most unfair. Conclusion: The decline in the mortality rate of under-five children is related to the improvement in the child health services. We should improve the health services of perinatal infants and pay attention to the health of children aged 1 to 4 years. The fairness of child health service is affected by the two-child policy. We should rationally allocate resources and strengthen support for the central and western regions.

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FREQUENCY AND CAUSES OF PERINATAL MORTALITY IN A TERTIARY CARE HOSPITAL IN PESHAWAR, PAKISTAN

Gomal Journal of Medical Sciences ◽

10.46903/gjms/16.01.1637 ◽

2018 ◽

Vol 16 (1) ◽

pp. 15-19

Author(s):

Maimoona Qadir ◽

Sohail Amir ◽

Samina Jadoon ◽

Muhammad Marwat

Keyword(s):

Mortality Rate ◽

Perinatal Mortality ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Age Groups ◽

Mortality Data ◽

Care Hospital ◽

Cross Sectional ◽

Medical Disorders ◽

Perinatal Mortality Rate

Background: Perinatal mortality rate indicates quality of care provided during pregnancy and delivery to the mother and to the neonate in its early neonatal period. The objective of this study was to determine the frequency and causes of perinatal mortality in a tertiary care hospital in Peshawar, Pakistan. Materials & Methods: This cross-sectional study was conducted at Department of Gynaecology & Obstetrics, Khyber Teaching Hospital, Peshawar, Pakistan from 1st January 2016 to 31st December 2016. The inclusion criteria was all singleton gestation with gestational age of at least 24 weeks presenting with perinatal mortality. Data was collected for the following variables; age groups (up to 20 years, 21-30 years, 31-40 years and > 40 years), booking status (yes/ no), period of gestation (24-31+6, 32-36+6, 37-39+6 and > 40 weeks), Foetal weight ( 3.5 kg) and cause of perinatal mortality. Results: Out of 4508 deliveries there were 288 perinatal deaths, including 228 stillbirths and 60 neonatal deaths, so perinatal mortality rate was 63.8/1000 births. 90.28% women were unbooked. Most common cause was hypertensive disorders of pregnancy (27.78%) followed by antepartum haemorrhage (25.71%) and then mechanical causes (13.88%). Congenital anomalies comprised 11.8% cases, neonatal problems 10.07% and maternal medical disorders for 4.16% cases. Cause of 4.16% cases remained unexplained. Conclusion: Appropriate strategies like control of identifiable causes, proper antenatal and postnatal care, healthy delivery practices and availability of emergency neonatal care facilities can bring down perinatal mortality rates.

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Analysis of selected perinatological indicators in the Slovak Republic in the years 2007–2018

Česká gynekologie ◽

10.48095/cccg2021102 ◽

2021 ◽

Vol 86 (2) ◽

pp. 102-109

Author(s):

Miroslav Korbeľ ◽

◽

Pavel Kaščák ◽

zuzana Nižňanská

Keyword(s):

Birth Weight ◽

Mortality Rate ◽

Low Birth Weight ◽

Perinatal Mortality ◽

Total Fertility Rate ◽

Very Low Birth Weight ◽

Slovak Republic ◽

In Utero ◽

Fertility Rate ◽

Live Births

Overview Objective: Analysis of perinatal mortality in the Slovak Republic during the years 2007–2018. Methods: Analysis of prospectively collected selected perinatal data in the years 2007–2018. Results: In the year 2007, there were 63 obstetrics units, 51,146 deliveries and that of live births 51,650 in the Slovak Republic. The number of obstetrics units decreased to 51 in the years 2018, the total number of deliveries increased to 57,085 and that of live births increased to 57,773. The total fertility rate in the years 2007–2018 increased from 1.27 to 1.54. The preterm deliveries rate increased from 7.3% in the year 2007 to 8.5% in the year 2010 and decreased to 7% in the year 2018. The perinatal mortality rate decreased from 6.2 in the year 2007 to 4.4 in the year 2017, increased again in the years 2018 to 5.0 and according to the criteria of WHO (World Health Organization) to 6.6 per 1,000 still- and live-births. During the years 2007–2018 at perinatal mortality stillbirth participate with 65%, low birth weight with 63% and severe congenital anomalies with 19%. Transport in utero to perinatological centers in the years 2007–2018 has decreased from 57 to 56% for infants 1,000–1,499 g and from 75 to 73% for infants below 1,000 g. Conclusion: In the year 2017, perinatology in the Slovak Republic reached the best result in the perinatal mortality rate – 4.4‰ (0.44%), but has increased to over 5‰ next year. To further reduce perinatal mortality in the Slovak Republic, it is necessary to improve the prenatal diagnosis of severe congenital abnormalities, transport in utero of very low birth weight fetuses, centralization of high-risk pregnancies, obstetric personnel and material-technical equipment of obstetricians and neonatal intensive care units. Keywords: perinatal mortality – preterm delivery – multiple pregnancy – low birth weight – very low birth weight – total fertility rate

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Neonatal and perinatal mortality trend among 23,000 babies delivered during three years at an urban university teaching hospital of Nepal

Journal of Patan Academy of Health Sciences ◽

10.3126/jpahs.v6i2.27239 ◽

2019 ◽

Vol 6 (2) ◽

pp. 90-95

Author(s):

Rateena Rajbhandari ◽

Puja Amatya ◽

Shova Shrestha

Keyword(s):

Birth Weight ◽

Mortality Rate ◽

Perinatal Mortality ◽

Mode Of Delivery ◽

Final Outcome ◽

University Teaching ◽

Microsoft Excel ◽

Live Births ◽

Perinatal Audit ◽

Urban University

Introductions: Perinatal mortality rate (PMR) of Nepal is 31 deaths per 1000 pregnancies and neonatal mortality rate (NMR) is 21 deaths per 1000 live births according to Nepal Demographic and Health Survey (NDHS) 2016. This study aims to analyse the trend of PMR and NMR of babies delivered at Patan hospital, Nepal. Methods: This was a retrospective study done in the department of Pediatrics to analyse the trend of neonatal and perinatal outcome of babies delivered during three years from April 2016 to March 2019 at Patan Hospital, Patan Academy of Health Sciences, Nepal. Data was collected from hospital records and perinatal audit. The mode of delivery (vaginal, instrumental, caesarian), birth status (sex, premature, still, live, APGAR, birth weight) and final outcome (neonatal and perinatal mortalities) were analyzed descriptively using Microsoft Excel 2010. Results: The final outcome of total 22937 deliveries during three years were PMR 4.34, corrected PMR 10.85 per 1000 total births and NMR 3.62 per 1000 live births. There were 22913 (99%) live births, 3090 (13.3%) had low birth weight, 11898 (52%) spontaneous vaginal delivery, 10700 (47%) cesarean and 339 (1.5%) instrumental deliveries. Conclusions: The overall PMR was 4.34 per 1000 total births and NMR was 3.62 per 1000 live births at Patan Hospital.

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