Maternal infectious diseases during pregnancy and obstetric complications in the etiology of distinct subtypes of schizophrenia: further evidence from maternal hospital records

1995 ◽  
Vol 10 (7) ◽  
pp. 326-330 ◽  
Author(s):  
E Franzek ◽  
G Stöber

SummaryOn the basis of 24 maternity hospital records, the current study investigated the validity of maternal recall and the relationship of maternal infections during pregnancy and obstetric complications (OCs) to different diagnostic subgroups of endogenous psychoses on which we reported previously in this journal. Maternal recall showed good agreement to maternity hospital records in the Lewis and Murray scale (ϑ = 0.74). With regard to infectious diseases during pregnancy maternal recall and records showed a weaker, but also good correlation (ϑ = 0.18). Psychoses with low genetic loading had more OCs than psychoses with high genetic loading. Maternal infectious diseases, especially during the fourth or fifth month of gestation, were significantly allocated to Leonhard's systematic schizophrenias. Data from maternity hospital records support our report that infectious diseases during midgestation and further perinatal complications seem to be important etiologic factors in systematic forms of schizophrenia without marked familial loading.

1990 ◽  
Vol 20 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Eadbhard O'Callaghan ◽  
Conall Larkin ◽  
John L. Waddington

SYNOPSISThe significance of the excess of obstetric complications which appears to characterize the histories of schizophrenic patients is critically dependent on the validity of the source of obstetric information, especially when this is obtained by maternal recall. Twenty-one biological mothers of 17 schizophrenic and four other patients were interviewed for their recollections of individual events characterizing the pregnancy and delivery relating to each patient. These were then compared with those events documented in maternity hospital records. Only in two of the 21 instances (9·5%) were inconsistencies of detail apparent which would have affected the designation of the relevant patient as having, or as not having, experienced major obstetric complication(s). It is concluded that maternal recall can be a surprisingly accurate source of obstetric information in relation to research on schizophrenia.


1994 ◽  
Vol 165 (3) ◽  
pp. 353-356 ◽  
Author(s):  
E. O'Callaghan ◽  
P. C. Sham ◽  
N. Takei ◽  
G. Murray ◽  
G. Glover ◽  
...  

BackgroundRecently, several investigators have reported an association between influenza epidemics and increased birth rates of ‘preschizophrenic’ individuals some four to six months later. Here we examine whether maternal exposure to other infectious diseases can also predispose the foetus to later schizophrenia.MethodTwo independent sets of dates of birth of first admission schizophrenic patients, born between 1938 and 1965 in England and Wales, were obtained from the Mental Health Enquiry in England and Wales. Data on the number of deaths per month from 16 infectious diseases between 1937 and 1965 in England and Wales were also collected. We used a Poisson regression model to examine the relationship between deaths from infectious diseases and schizophrenic births.ResultsIn the two separate data sets, increased national deaths from bronchopneumonia preceded, by three and five months respectively, increased numbers of schizophrenic births. We did not find any other significant associations between schizophrenic births and any of the other 15 infectious diseases.ConclusionsThe association between deaths from bronchopneumonia and increased schizophrenic births some months later may be a reflection of the fact that bronchopneumonia deaths increase markedly during influenza epidemics.


1985 ◽  
Vol 15 (3) ◽  
pp. 275-288 ◽  
Author(s):  
Christina M. Mumma ◽  
Jeanne Quint Benoliel

The study was designed to examine the relationship of cause of dying, length of hospital stay, and age to medical treatment effort orientation and amount of work effort expended. The data were obtained through retrospective analysis of patient hospital records of 184 adults who died in an urban teaching hospital. Descriptive variables included demographic characteristics, ascribed medical condition day of death, and code status. Multivariate analysis of variance was used to analyze the relationship of the dependent variables to the independent variables. The findings showed that the medical treatment orientation was overwhelmingly toward the cure end of the care-cure continuum, despite the fact that the majority of patients had been designated no code (non-use of cardiopulmonary resuscitation) and had conditions labeled by their physicians as either grim prognosis or terminal.


2011 ◽  
Vol 321 ◽  
pp. 230-233
Author(s):  
Guang Shen Xu ◽  
Jing Gong

There is more reaction heat of layer curing during fabrication process, so the integral SL System has shrinkage deformation. To improve the building accuracy of integral SL System, the deformation of integral SL is analyzed, a little deflection temperature stress bending differential equation, which describe the relationship of deformation with other parameters in integral SL System, is established with elastic mechanics. The relationship of distortion deformation with layer thickness, contract rate of resin, temperature difference and locations is obtained through the equation. The deformation of a bridge model is simulated with ANSYS software in different building condition. In the simulation process, curing units are activated layer by layer with the method of elements birth and death. The simulation results are in good agreement with the equation. The research results lay a foundation for building high accuracy objects with integral SL System.


2018 ◽  
Vol 3 (2) ◽  
pp. 103
Author(s):  
Rama Beka Sariy ◽  
Betty Yosephin Simanjuntak ◽  
Desri Suryani

Infants who fail to grow much occur in the third month or fourth month of early life. Early breastfeeding of the ASI causes mothers not to give breast milk and cause infectious diseases that result in stunting in infants. The purpose of this research is to find out the relationship of early breastfeeding with nutritional status (PB/U) age 4-7 months in Ratu Samban Sub-district of Bengkulu City.  This research uses analytic observational with a cross-sectional design. The results showed the nutritional status of PB / U short category 18.3% and MP ASI early 66.7% while the statistical test showed probability (p) of 0.273 (p> 0.05).  There is no correlation between early breastfeeding of MP and nutritional status of PB / U age 4-7 months in Ratu Samban Sub-district of Bengkulu City. Need to do re-research a using Cohort method and with other variables.Bayi yang gagal tumbuh banyak terjadi pada bulan ketiga atau bulan ke empat awal kehidupan. Pemberian MP ASI dini mengakibatkan ibu tidak berusaha memberikan ASI dan menyebabkan terjadinya penyakit infeksi yang mengakibatkan stunting pada balita. Tujuan dari penelitian ini adalah untuk mengetahui hubungan pemberian MP-ASI dini dengan status gizi (PB/U) pada bayi usia 4-7 bulan di Kecamatan Ratu Samban Kota Bengkulu. Jenis penelitian ini menggunakan observasional analitik dengan desain cross sectional. Hasil penelitian menunjukan status gizi PB/U kategori pendek 18,3% dan MP ASI dini 66,7% sedangkan uji statistik menunjukkan nilai probabilitas (p) sebesar 0,273 (p > 0,05).  Tidak ada hubungan antara pemberian MP ASI dini dengan status gizi PB/U usia 4-7 bulan di Kecamatan Ratu Samban Kota Bengkulu . Hal ini berkaitan dengan pemberian makanan pendamping ASI sementara sebagai makanan prelaktal sebelum ASI ibu keluar dan diberikan dalam jumlah sedikit. Lebih baik dilakukan penelitian lanjutan dengan menggunakan metode Kohort dan dengan variabel lain.


2014 ◽  
Vol 610 ◽  
pp. 35-39
Author(s):  
Kai Cheng Yao ◽  
Dong Hua Zhou ◽  
Wen Yuan Liao ◽  
Long Qi Li ◽  
Guo Fei Li ◽  
...  

Based on the assumption of plane section, ideal elastic-plastic model of steel and the constitutive relations of concrete in Chinese Code for Design of Concrete Structures, numerical method is used to analyze the relationship of the axial force-moment-curvature on RC section. After dividing the normal section into strips, we adopt the secant stiffness iteration method (according to the results of each iteration, modify the secant stiffness through changing the elastic modulus of materials) to compile computer program. The results of the paper show a good agreement with those of the analytical method. Comparing with the analytical method, the numerical method of the paper can be wildly used in the application.


2018 ◽  
Vol 7 ◽  
Author(s):  
Louise O'Rourke ◽  
Gerard Clarke ◽  
Aoife Nolan ◽  
Claire Watkins ◽  
Timothy G. Dinan ◽  
...  

AbstractBreast milk is the only source of the essential amino acid tryptophan (TRP) in breast-fed infants. Low levels of TRP could have implications for infant neurodevelopment. The objectives of the present study were to compare the relationship of TRP and its neuroactive pathway metabolites kynurenine (Kyn) and kynurenic acid (KynA) in preterm and term expressed breast milk (EBM) in the first 14 d following birth, and the relationship of TRP metabolism to maternal stress and immune status. A total of twenty-four mothers were recruited from Cork University Maternity Hospital: twelve term (>38 weeks) and twelve preterm (<35 weeks). EBM samples were collected on days 7 and 14. Free TRP, Kyn and KynA were measured using HPLC, total TRP using MS, cytokines using the Meso Scale Discovery (MSD) assay system, and cortisol using a cortisol ELISA kit. Although total TRP was higher in preterm EBM in comparison with term EBM (P< 0·05), free TRP levels were lower (P< 0·05). Kyn, KynA and the Kyn:TRP ratio increased significantly in term EBM from day 7 to day 14 (P< 0·05), but not in preterm EBM. TNF-α, IL-6 and IL-8 were higher in day 7 preterm and term EBM in comparison with day 14. There were no significant differences between term and preterm EBM cortisol levels. Increased availability of total TRP, lower levels of free TRP and alterations in the temporal dynamics of TRP metabolism in preterm compared with term EBM, coupled with higher EBM inflammatory markers on day 7, may have implications for the neurological development of exclusively breast-fed preterm infants.


2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Hesty R. Masela ◽  
Shirley Kawengian ◽  
Nelly Mayulu

Abstract: Infectious diseases are still major problems in many developing countries, including Indonesia. The effectiveness of exclusive breastfeeding is manifested in the reduction of specific disease incidences in infants who receive breast milk compared to formula -fed infants. This study used correlation method with a cross sectional design. Respondents were 90 women who had toddlers (aged less than 3 years) with histories of infectious disesases from September 2014 until Desember 2014. Data were obtained by using questionnaires. The results showed that there were as many as 23 toddlers (26%) with exclusive breastfeeding. History of infectious disease was found in 26 toddlers (28.9%). Regarding the relationship of exclusive breastfeeding with a history of infectious disease (α = 0.05) was found (p) = 0.001 and x2 = 11.883. There was a relationship between breastfeeding with a history of infectious disease in children aged less than 1-3 years in the Mopusi village, Lolayan Bolaang Mongondow Induk.Keywords: exclusive breastfeeding , history of infectious diseases , toddlers .Abstrak: Penyakit infeksi masih merupakan penyakit utama di banyak Negara berkembang, terutama Indonesia. Efektivitas ASI dalam mengendalikan infeksi dapat dibuktikan dengan berkurangnya kejadian beberapa penyakit spesifik pada bayi yang mendapat ASI di banding bayi yang mendapat susu formula. Penelitian ini bertujuan untuk mengetahui hubungan antara pemberian ASI ekslusif dengan riwayat penyakit infeksi pada batita di desa Mopusi kecamatan Lolayan kabupaten Bolaang Mongondow Induk. Penelitian ini menggunakan metode korelasi dengan pendekatan potong lintang. Responden ialah ibu yang memiliki batita dengan riwayat penyakit infeksi sebanyak 90 orang di desa Mopusi pada bulan September 2014-Desember 2014. Pengambilan data dengan menggunakan kuesioner. Hasil penelitian memperlihatkan sebanyak 23 batita (26%) mendapatkan ASI ekslusif. Riwayat penyakit infeksi ditemukan pada 26 batita (28,9%). Mengenai hubungan pemberian ASI ekslusif dengan riwayat penyakit infeksi (α = 0,05) didapatkan p = 0,001 dan x2 = 11,883. Simpulan: Terdapat hubungan antara pemberian ASI dan riwayat penyakit infeksi pada anak umur 1-3 tahun di desa Mopusi kecamatan Lolayan kabupaten Bolaang Mongondow Induk.Kata kunci: ASI ekslusif, riwayat penyakit infeksi, batita


Sign in / Sign up

Export Citation Format

Share Document