New self-healing hydrogels based on reversible physical interactions and their potential applications

2019 ◽  
Vol 118 ◽  
pp. 176-185 ◽  
Author(s):  
Loredana Elena Nita ◽  
Aurica P. Chiriac ◽  
Alina Gabriela Rusu ◽  
Maria Bercea ◽  
Alina Ghilan ◽  
...  
Polymers ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2261
Author(s):  
Sheila Maiz-Fernández ◽  
Leyre Pérez-Álvarez ◽  
Leire Ruiz-Rubio ◽  
Jose Luis Vilas-Vilela ◽  
Senentxu Lanceros-Mendez

In situ hydrogels have attracted increasing interest in recent years due to the need to develop effective and practical implantable platforms. Traditional hydrogels require surgical interventions to be implanted and are far from providing personalized medicine applications. However, in situ hydrogels offer a wide variety of advantages, such as a non-invasive nature due to their localized action or the ability to perfectly adapt to the place to be replaced regardless the size, shape or irregularities. In recent years, research has particularly focused on in situ hydrogels based on natural polysaccharides due to their promising properties such as biocompatibility, biodegradability and their ability to self-repair. This last property inspired in nature gives them the possibility of maintaining their integrity even after damage, owing to specific physical interactions or dynamic covalent bonds that provide reversible linkages. In this review, the different self-healing mechanisms, as well as the latest research on in situ self-healing hydrogels, is presented, together with the potential applications of these materials in tissue regeneration.


Nanophotonics ◽  
2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Qingqing Cheng ◽  
Juncheng Wang ◽  
Ling Ma ◽  
Zhixiong Shen ◽  
Jing Zhang ◽  
...  

AbstractAiry beams exhibit intriguing properties such as nonspreading, self-bending, and self-healing and have attracted considerable recent interest because of their many potential applications in photonics, such as to beam focusing, light-sheet microscopy, and biomedical imaging. However, previous approaches to generate Airy beams using photonic structures have suffered from severe chromatic problems arising from strong frequency dispersion of the scatterers. Here, we design and fabricate a metasurface composed of silicon posts for the frequency range 0.4–0.8 THz in transmission mode, and we experimentally demonstrate achromatic Airy beams exhibiting autofocusing properties. We further show numerically that a generated achromatic Airy-beam-based metalens exhibits self-healing properties that are immune to scattering by particles and that it also possesses a larger depth of focus than a traditional metalens. Our results pave the way to the realization of flat photonic devices for applications to noninvasive biomedical imaging and light-sheet microscopy, and we provide a numerical demonstration of a device protocol.


2021 ◽  
Vol 9 (7) ◽  
pp. 3931-3939
Author(s):  
Shiqiang Song ◽  
Honghao Hou ◽  
Jincheng Wang ◽  
Pinhua Rao ◽  
Yong Zhang

A high-stretchability, high-strength, tear-resistant, self-healing and adhesive elastomer is prepared through a facile and effective physical blending strategy. The elastomer shows potential applications in e-skin devices.


Soft Matter ◽  
2021 ◽  
Author(s):  
Yuxing Shan ◽  
shuai liang ◽  
Xiangkai Mao ◽  
Jie Lu ◽  
Lili Liu ◽  
...  

Abstract. Stretchable elastomers with superhydrophobic surfaces have potential applications in wearable electronics. However, various types of damage inevitably occur on these elastomers in actual application, resulting in deterioration of the...


Gels ◽  
2018 ◽  
Vol 4 (3) ◽  
pp. 67 ◽  
Author(s):  
Pasquale Sacco ◽  
Franco Furlani ◽  
Gaia de Marzo ◽  
Eleonora Marsich ◽  
Sergio Paoletti ◽  
...  

Chitosan macro- and micro/nano-gels have gained increasing attention in recent years, especially in the biomedical field, given the well-documented low toxicity, degradability, and non-immunogenicity of this unique biopolymer. In this review we aim at recapitulating the recent gelling concepts for developing chitosan-based physical gels. Specifically, we describe how nowadays it is relatively simple to prepare networks endowed with different sizes and shapes simply by exploiting physical interactions, namely (i) hydrophobic effects and hydrogen bonds—mostly governed by chitosan chemical composition—and (ii) electrostatic interactions, mainly ensured by physical/chemical chitosan features, such as the degree of acetylation and molecular weight, and external parameters, such as pH and ionic strength. Particular emphasis is dedicated to potential applications of this set of materials, especially in tissue engineering and drug delivery sectors. Lastly, we report on chitosan derivatives and their ability to form gels. Additionally, we discuss the recent findings on a lactose-modified chitosan named Chitlac, which has proved to form attractive gels both at the macro- and at the nano-scale.


Biomimetics ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 30 ◽  
Author(s):  
Amanda Andersen ◽  
Yaqing Chen ◽  
Henrik Birkedal

The blue mussel incorporates the polyphenolic amino acid l-3,4-dihydroxyphenylalanine (DOPA) to achieve self-healing, pH-responsiveness, and impressive underwater adhesion in the byssus threads that ensure the survival of the animal. This is achieved by a pH-dependent and versatile reaction chemistry of polyphenols, including both physical interactions as well as reversible and irreversible chemical bonding. With a short introduction to the biological background, we here review the latest advances in the development of smart materials based on the metal-chelating capabilities of polyphenols. We focus on new ways of utilizing the polyphenolic properties, including studies on the modifications of the nearby chemical environment (on and near the polyphenolic moiety) and on the incorporation of polyphenols into untraditional materials.


2012 ◽  
Vol 8 ◽  
pp. 349-370 ◽  
Author(s):  
Gareth L Nealon ◽  
Romain Greget ◽  
Cristina Dominguez ◽  
Zsuzsanna T Nagy ◽  
Daniel Guillon ◽  
...  

Liquid-crystalline nanoparticles represent an exciting class of new materials for a variety of potential applications. By combining supramolecular ordering with the fluid properties of the liquid-crystalline state, these materials offer the possibility to organise nanoparticles into addressable 2-D and 3-D arrangements exhibiting high processability and self-healing properties. Herein, we review the developments in the field of discrete thermotropic liquid-crystalline nanoparticle hybrids, with special emphasis on the relationship between the nanoparticle morphology and the nature of the organic ligand coating and their resulting phase behaviour. Mechanisms proposed to explain the supramolecular organisation of the mesogens within the liquid-crystalline phases are discussed.


2016 ◽  
Vol 13 (122) ◽  
pp. 20160300 ◽  
Author(s):  
Quan Xu ◽  
Wenwen Zhang ◽  
Chenbo Dong ◽  
Theruvakkattil Sreenivasan Sreeprasad ◽  
Zhenhai Xia

With millions of years of natural evolution, organisms have achieved sophisticated structures, patterns or textures with complex, spontaneous multifunctionality. Among all the fascinating characteristics observed in biosystems, self-cleaning ability is regarded as one of the most interesting topics in biomimicry because of its potential applications in various fields such as aerospace, energy conversion and biomedical and environmental protection. Recently, in-depth studies have been carried out on various compelling biostructures including lotus leaves, shark skins, butterfly wings and gecko feet. To understand and mimic their self-cleaning mechanisms in artificial structures, in this article, recent progress in self-cleaning techniques is discussed and summarized. Based on the underlying self-cleaning mechanisms, the methods are classified into two categories: self-cleaning with water and without water. The review gives a succinct account of the detailed mechanisms and biomimetic processes applied to create artificial self-cleaning materials and surfaces, and provides some examples of cutting-edge applications such as anti-reflection, water repellence, self-healing, anti-fogging and micro-manipulators. The prospectives and directions of future development are also briefly proposed.


RSC Advances ◽  
2016 ◽  
Vol 6 (77) ◽  
pp. 73140-73147 ◽  
Author(s):  
Zhiming Gou ◽  
Yujing Zuo ◽  
Shengyu Feng

A simpler approach is developed to obtain recyclable self-healing polysiloxane networks based on the thiol-ene reaction and Diels–Alder (DA) reaction which found potential applications in recyclable adhesives especially for glass bonding.


Gels ◽  
2016 ◽  
Vol 2 (2) ◽  
pp. 16 ◽  
Author(s):  
Satu Strandman ◽  
X.X. Zhu

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