Anxiety and depression in patients with hepatic versus cardiac disease

BackgroundIn both hepatic and cardiac disease, a bidirectional relationship exists between somatic and psychiatric symptoms: is anxiety/depression caused by the somatic burden of the symptoms or the psychiatric symptoms and stress are an important pathophysiologic factor for the somatic disease?ObjectiveThe objectives of our observational study were to see if any differences exist regarding the anxiety level in patients with hepatic versus cardiac disease and if the depressive symptomatology differs between the two groups of patients.Materials and methods: We conceived a 2X2 study model by including two independent variables (the somatic pathology, hepatic and cardiac) and two dependent variables (anxiety and depression) which included 66 patients (35 with hepatic and 31 with cardiac pathology) who completed both STAI X1 scale for anxiety and BECK scale for depression with good reliability for both scales (Cronbach's alpha value of 0.74 for STAI X1 and 0.76 for BECK), data analyzed with SPSS 17.ResultsWe obtained a low level for anxiety (mean = 17.76) and a medium level for depression (mean = 49), both anxiety and depression level being higher in the patients with hepatic disease versus cardiac patients (P > 0.05). The patients with hepatic failure had a higher medium anxiety score (54.66) vs cardiac failure patients (42.61). The depression score was 19.71 in patients with hepatic failure and 15.55 in patients with cardiac failure.ConclusionBoth anxiety and depression severity scores were increased in patients with hepatic disease vs patients with cardiac disease in the studied groups.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Occurence of post-traumatic stress symptoms, anxiety and depression in the acute phase of transient ischemic attack and stroke

10.21203/rs.3.rs-104881/v1 ◽

2020 ◽

Author(s):

Helge HO Müller ◽

Katharina Czwalinna ◽

Ruihao Wang ◽

Caroline Lücke ◽

Alexandra P. Lam ◽

...

Keyword(s):

Acute Phase ◽

Psychiatric Symptoms ◽

Depression Score ◽

Anxiety And Depression ◽

Post Traumatic Stress ◽

Stroke Patients ◽

Stress Symptoms ◽

Post Traumatic ◽

Ischemic Attack ◽

And Coping

Abstract Background Rates of post-traumatic stress symptoms, anxiety and depression are increased in patients having experienced a transient ischemic attack (TIA) or stroke several months ago. However, data of psychiatric symptoms in the acute phase within the first days after ictus are lacking. Methods In 20 patients with stroke and 33 patients with TIA we assessed disease severity by means of the NIHSS, levels of depression and anxiety by HADS, PTSD-like symptoms by PC-PTSD, quality of life (HrQoL) by SF-12, and coping style by brief COPE Inventory within the first 5 days after ictus. Results NIHSS on admission was lower in patients with TIA (0 ± 1) than in patients with stroke (3 ± 2, p < 0.001). HADS depression score was significantly higher in patients with stroke (7.0 ± 4.5) than in patients with TIA (4.9 ± 4.0). HADS anxiety score, HrQoL and coping styles were similar between TIA and stroke patients (p > 0.05). 5 and 3 of 33 TIA patients as well as 4 and 3 of 20 stroke patients had at least 11 points in the HADS anxiety and depression score respectively (p = 0.001). 2 of 33 TIA patients and 2 of 20 stroke patients had more than 2 points in the PC-PTSD (p = 0.646). We did not find consistent correlations between the NIHSS and the psychometric parameters. Conclusions Within the first five days after patients having experienced a TIA or stroke PTSD-like, anxious and depressive symptoms are more common than in the general population. As the acute psychological status after ictus is predictive for psychiatric comorbidity years later physicians should pay attention and adequately treat psychiatric symptoms already in the acute phase of stroke.

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AB0897-HPR EVALUATION OF ANXIETY AND DEPRESSION IN PATIENTS WITH KNEE OSTEOARTHRITIS USING THE HAD “HOSPITAL ANXIETY AND DEPRESSION SCALE”

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2021-eular.3835 ◽

2021 ◽

Vol 80 (Suppl 1) ◽

pp. 1472.1-1472

Author(s):

M. Brahem ◽

S. Abdellatif ◽

H. Hachfi ◽

A. Ben Salem ◽

R. Sarraj ◽

...

Keyword(s):

Knee Osteoarthritis ◽

Depressive Symptomatology ◽

Depression Scale ◽

Womac Score ◽

Depression Score ◽

Anxiety Score ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Significant Disability ◽

The Mean

Background:Knee osteoarthritis is considered to be one of the most common causes of functional impairment, which affects the quality of life of patients leading to severe mood disorders. Our goal is to evaluate the frequency of depression and anxiety in patients with knee osteoarthritis.Objectives:Evaluate the frequency of depression and anxiety in patients with knee osteoarthritis.Methods:This is a cross-sectional study over a period of 7 months from February to August 2016, including consecutively patients who consulted in the Rheumatology department at Mahdia university hospital for knee osteoarthritis. We evaluated for each patient a validated version of HAD “Hospital Anxiety and Depression scale”. This score includes 14 items each one rated from 0 to 3 and two components including depression and anxiety.Results:We included in our study 66 patients (56 women and 10 men) with an average age of 60.3 years [40-90 years]. Knee osteoarthritis was bilateral in 56.1% of cases. The examination found limited mobility of the knee in 45.5% and flessum in 13.8% of cases. Standard radiography showed stage 1 knee osteoarthritis in 4.5%, stage 2 in 31.8%, stage 3 in 56.1% and stage 4 in 7.6% of cases. All our patients were treated with analgesics, NSAIDs in 95.5%, local corticosteroid infiltrations in 43.9% and hyaluronic acid in 7.6% of cases.The mean visual analog scale(VAS)was 5.84 ±1.7 out of 10 [2-9]. The mean overall WOMAC index was 47.15±15.6 [12-82]. The average Lequesne index was 16.8±13.1, moderate disability was found in 3% of cases, significant disability in 6.1% of cases, very significant disability in 18.2% of cases and extreme disability in 72.7% of cases. The mean depression score was 9.3±2.6 [4-16], with 24.6% of the patients had no depressive symptomatology (score ≤7), 40% had doubtful depressive symptomatology (score between 8 and 10) and 35.4% of them had certain depressive symptomatology (score ≥11).The mean anxiety score was 8.88 ± 4 [0-19], 33.3% of patients had no anxiety symptoms (score ≤ 7), 34.8% had doubtful anxiety (score between 8 and 10) and 31.8% had certain anxiety (score ≥11). The statistical study found a significant correlation between the depression score and WOMAC score, but we did not find an association with age, sex, radiological stage, mobility limitation and VAS. Regarding anxiety, there was a correlation with age, WOMAC score and female gender. On the other hand, there was no correlation with VAS, Lequesne score, radiological stage and limitation of mobility.Conclusion:Although knee osteoarthritis appears to be a benign pathology, its impact can be severe, including depression and anxiety, which are mainly influenced by the degree of functional disability. Hence psychological care is sometimes necessary in these chronic degenerative diseases.Disclosure of Interests:None declared

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Occurence of Post-Traumatic Stress Symptoms, Anxiety and Depression in the Acute Phase of Transient Ischemic Attack and Stroke

Psychiatric Quarterly ◽

10.1007/s11126-020-09873-9 ◽

2021 ◽

Author(s):

Helge H. O. Müller ◽

Katharina Czwalinna ◽

Ruihao Wang ◽

Caroline Lücke ◽

Alexandra P. Lam ◽

...

Keyword(s):

Acute Phase ◽

Psychiatric Symptoms ◽

Depression Score ◽

Anxiety And Depression ◽

Post Traumatic Stress ◽

Stroke Patients ◽

Stress Symptoms ◽

Post Traumatic ◽

Ischemic Attack ◽

And Coping

AbstractRates of post-traumatic stress symptoms, anxiety and depression are increased in patients having experienced a transient ischemic attack (TIA) or stroke several months ago. However, data of psychiatric symptoms in the acute phase within the first days after ictus are lacking. In 20 patients with stroke and 33 patients with TIA we assessed disease severity by means of the NIHSS, levels of depression and anxiety by HADS, PTSD-like symptoms by PC-PTSD, quality of life (HrQoL) by SF-12, and coping style by brief COPE Inventory within the first 5 days after ictus. NIHSS on admission was lower in patients with TIA (0 ± 1) than in patients with stroke (3 ± 2, p < 0.001). HADS depression score was significantly higher in patients with stroke (7.0 ± 4.5) than in patients with TIA (4.9 ± 4.0). HADS anxiety score, HrQoL and coping styles were similar between TIA and stroke patients (p > 0.05). 5 and 3 of 33 TIA patients as well as 4 and 3 of 20 stroke patients had at least 11 points in the HADS anxiety and depression score respectively (p = 0.001). 2 of 33 TIA patients and 2 of 20 stroke patients had more than 2 points in the PC-PTSD (p = 0.646). We did not find consistent correlations between the NIHSS and the psychometric parameters. Within the first five days after patients having experienced a TIA or stroke PTSD-like, anxious and depressive symptoms are more common than in the general population. As the acute psychological status after ictus is predictive for psychiatric comorbidity years later physicians should pay attention and adequately treat psychiatric symptoms already in the acute phase of stroke.Trial Registration: German Clinical Trials Register, DRKS00021730, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00021730, registered 05/19/2020- Retrospectively registered.

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Family Environment and Its Correlation with Anxiety and Depression: A Study on Heart Patients

International Journal of Indian Psychology ◽

10.25215/0302.109 ◽

2016 ◽

Vol 3 (2) ◽

Author(s):

Dr. Meena Jain ◽

Saloni Chandalia

Keyword(s):

Heart Disease ◽

Family Environment ◽

Heart Attack ◽

Psychiatric Symptoms ◽

Disease Risk ◽

Positive Association ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Increased Risk ◽

Artery Disease

This research paper deals with the Family Environment and its Correlation with Anxiety and Depression level among persons with Heart Disease. There had been a number of researches that investigated that ischemic heart disease patients who suffer significant anxiety have close to a 5-fold increased risk of experiencing frequent angina and those with depression have more than a 3-fold increased risk for these episodes. This observed link between psychiatric symptoms and angina underlines the importance of treating anxiety and depression in cardiac patients, according to study co author Dr Mark D Sullivan (University of Washington School of Medicine, Seattle). To gather the needed data, Hamilton Anxiety Scale and Becks Depression Inventory were used. As stated from literatures, for people with heart dysfunction, depression and anxiety can increase the risk of an adverse cardiac event such as a heart attack or blood clots. For people who do not have heart disease, depression and anxiety can also increase the risk of a heart attack and development of coronary artery disease. Researchers have also emphasized on the role of family psychosocial environment and its positive association with the Coronary Heart Disease risk.

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Dimensions of neuroses seen in primary-care settings

Psychological Medicine ◽

10.1017/s0033291700025022 ◽

1987 ◽

Vol 17 (2) ◽

pp. 461-470 ◽

Cited By ~ 108

Author(s):

D. P. Goldberg ◽

K. Bridges ◽

P. Duncan–Jones ◽

D. Grayson

Keyword(s):

Primary Care ◽

Psychiatric Symptoms ◽

Latent Trait ◽

Anxiety And Depression ◽

Symptom Dimensions ◽

Symptoms Of Depression ◽

Primary Care Settings ◽

Severe Manifestation ◽

The Common ◽

Highly Correlated

SynopsisThis study uses methods of latent trait analysis to examine the relationships between psychiatric symptoms that constitute the common psychiatric disorders encountered in primary-care settings. Two highly correlated symptom dimensions of anxiety and depression are shown to underlie these disorders. Neurovegetative sysmptoms of depression are shown to be on the same dimension as psychic symptoms of depression, but to represent a more severe manifestation of depression.

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Culturally Sensitive Assessment of Anxious-Depressive Distress in Vietnam: Avoiding Category Truncation

Transcultural Psychiatry ◽

10.1177/1363461518764500 ◽

2018 ◽

Vol 55 (3) ◽

pp. 384-404 ◽

Cited By ~ 5

Author(s):

Devon E. Hinton ◽

Amie Alley Pollack ◽

Bahr Weiss ◽

Lam T. Trung

Keyword(s):

Psychiatric Symptoms ◽

Anxiety And Depression ◽

Strongly Correlated ◽

General Survey ◽

General Anxiety Disorder ◽

General Anxiety ◽

Study Results ◽

Standing Up ◽

Patient Health ◽

Highly Correlated

The present study investigated what complaints are prominent in psychologically distressed Vietnamese in Vietnam beyond standard symptoms assessed by Western diagnostic instruments for anxiety and depression. To form the initial Vietnamese Symptom and Cultural Syndrome Addendum (VN SSA), we reviewed the literature, consulted experts, and conducted focus groups. The preliminary VN SSA was then used in a general survey (N = 1004) of five provinces in Vietnam. We found that the VN SSA items were highly and significantly correlated with a measure of anxious-depressive psychopathology (a composite measure of the General Anxiety Disorder-7; Posttraumatic Diagnostic Scale; and Patient Health Questionnaire-9). The VN SSA item most highly correlated to anxious-depressive psychopathology was “thinking a lot” ( r = .54), reported by 15.8% of the sample. Many other symptoms in the addendum also were prominent, such as orthostatic dizziness (i.e., dizziness upon standing up; r = .41), reported by 22.9% of the sample. By way of comparison, somatic complaints more typically assessed to profile Western anxious-depressive distress, such as palpitations, were less prominent, as evidenced by being less strongly correlated to Western psychiatric symptoms and being less frequent (e.g., palpitations: r = .31, 7.1% of the sample). Study results suggest that to avoid category truncation when profiling anxious-depressive distress among Vietnamese that items other than those in standard psychopathology measures should also be assessed.

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Fear of Cancer Recurrence Is Highly Prevalent and Linearly Associates With Anxiety and Depression in Chinese Breast Cancer Patients

10.21203/rs.3.rs-1153816/v1 ◽

2022 ◽

Author(s):

Zhensheng Li ◽

Yue Li ◽

Yunjiang Liu ◽

Jun Zhang ◽

Xiaohui Ji ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Recurrence ◽

Depression Score ◽

Fear Of Cancer Recurrence ◽

Anxiety And Depression ◽

Breast Cancer Patients ◽

Distress Screening ◽

Reference Analysis ◽

Cross Sectional ◽

Fear Of Cancer

Abstract Objective: To characterize the fear of cancer recurrence (FCR) and its relationship with anxiety and depression and quality of life (QoL) among Chinese breast cancer (BC) patients in China. Methods: Patients completed the questionnaires of QLQ-C30, QLQ-BR32 and HAD to assess FCR, QoL, anxiety and depression before radiotherapy. A cross-sectional analysis was performed. Chi-square and non-parametric tests and multivariate ordinal logistic regressions (mOLR) were utilized for reference analysis. Final covariates included age, BMI, TNM, surgery, chemotherapy, pain, and sleep disturbance. Results: From July 2015 to December 2016, 463 patients were prospectively enrolled. Their age mean (range) were 47 (19 - 89) years old. In total, 327 patients (70.6%) reported having FCR ‘a little bit’ (51.2%), ‘some’ (12.1%) and ‘very much’ (7.3%) in the past week. FCR severity ordered above (incl. ‘no’) was associated with anxiety score (median 1.5, 5.0, 7.0, 8.5 and level (‘abnormal’ rate 0%, 3.4%, 12.5%, 26.5%), depression score (median 2.0, 4.0, 6.0, 6.5) and level (‘abnormal’ rate 2.2%, 3.4%, 5.4%, 17.7%) (all p<0.001). mOLR showed that compared to ‘no’, three higher levels of FCR were associated with one level increase of anxiety with OR (p) as 1.983 (0.076), 4.291 (0.001), 8.282 (<0.001) and depression with OR (p) as 1.903 (0.062), 2.262 (0.065), 4.205 (0.004), respectively. FCR severity also was inversely associated with most QoL function scores (p<0.001). Conclusions: FCR was prevalent in Chinese BC patients and linearly associated with anxiety, depression and low QoL. It seems that a single-item question for FCR is a valid surrogate tool for distress screening in this population.

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Aberrant activation within auditory network is associated with psychiatric comorbidities in interictal migraineurs without aura

10.21203/rs.3.rs-36497/v1 ◽

2020 ◽

Author(s):

Heng-Le Wei ◽

Yu-Chen Chen ◽

Yu-Sheng Yu ◽

Xi Guo ◽

Gang-Ping Zhou ◽

...

Keyword(s):

Auditory Cortex ◽

Resting State ◽

Psychiatric Symptoms ◽

Brain Activation ◽

Superior Temporal Gyrus ◽

Anxiety And Depression ◽

Intracranial Volume ◽

Healthy Controls ◽

Postcentral Gyrus ◽

Underlying Mechanisms

Abstract Background: Resting-state functional magnetic resonance imaging has confirmed auditory network dysfunction in migraine without aura (MwoA). Epidemiological investigations have disclosed that migraine is comorbid with many psychiatric symptoms. However, the underlying mechanisms of auditory cortex dysfunction linked to psychiatric disorders in MwoA remain unclear. The present study aimed to explore associations between brain activation in the auditory cortex and clinical and psychiatric characteristics in patients with MwoA during interictal periods.Methods: Resting-state data were acquired from patients with episodic MwoA (n=34) and healthy controls (n=30). Independent component analysis was used to extract and calculate the resting-state auditory network. Subsequently, we analyzed the correlations between spontaneous activation in the auditory cortex and clinical and psychiatric features in MwoA.Results: Compared with healthy controls, patients with MwoA showed increased activation in the left auditory cortex (i.e., superior temporal gyrus (STG), postcentral gyrus (PoCG) and insula). Brain activation in the left STG was positively correlated with anxiety scores, and activation in the left PoCG was negatively correlated with anxiety and depression scores. No significant differences were found in intracranial volume between the two groups.Conclusions: This study indicated that functional impairment and altered integration within the auditory cortex existed in patients with MwoA in the interictal period, suggesting that auditory cortex disruption as a biomarker may be implemented for the early diagnosis and prediction of neuropsychiatric impairment in MwoA.

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Neuroprotective therapy in chronic cerebrovascular diseases

Russian neurological Journal ◽

10.30629/2658-7947-2021-26-4-46-49 ◽

2021 ◽

Vol 26 (4) ◽

pp. 46-49

Author(s):

O. V. Kim ◽

Yo. N. Madzhidova ◽

F. R. Sharipov

Keyword(s):

Mini Mental State Examination ◽

Depression Scale ◽

Neurological Status ◽

Cerebrovascular Diseases ◽

Depression Score ◽

Anxiety And Depression ◽

Basic Therapy ◽

Neuroprotective Therapy ◽

State Examination ◽

Moca Score

Introduction. In chronic cerebrovascular diseases (CVD), neuroprotective medications, the effectiveness of which requires further study, are widely used. The effectiveness of Cytoflavinum in patients with chronic CVD was evaluated.Material and methods. The data of 60 patients (35 women and 25 men) with chronic CVD were analyzed. 30 patients, included in the main group (mean age 61 ± 5.87 years old), in addition to basic therapy (antihypertensive, antithrombotic drugs, statins), received Cytoflavinum according to the following scheme: 1 time a day in the morning intravenously 10.0 ml for 10 days, then 2 tablets 2 times a day for 30 days. 30 patients in the comparison group (mean age 59.8 ± 8.7 years old) received only basic therapy. An analysis of patient complaints, neurological status was carried out. Mini Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), Hospital Anxiety and Depression Scale (HADS) were used.Results. In the group of patients taking Cytoflavinum, there was a decrease in the frequency and intensity of headache, dizziness, an increase in MMSE score from 26.32 ± 0.86 to 28.05 ± 1.36 (p ≤ 0.05), in MoCA score from 25.35 ± 0.96 to 27.88 ± 1.13 (p ≤ 0.05), decrease in anxiety score from 8.82 ± 1.31 to 5.2 ± 2.82 (p ≤ 0.05) and decrease in HADS depression score from 8.31 ± 1.85 to 4.6 ± 3.15 (p ≤ 0.05).Conclusion. The inclusion of Cytoflavinum in the treatment regimen for patients with chronic CVD helps to reduce the frequency and intensity of headaches and dizziness, improve cognitive functions, and reduce the level of anxiety and depression.

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A novel multidisciplinary approach to the management of end-stage macular disease

British Journal of Visual Impairment ◽

10.1177/02646196211032694 ◽

2021 ◽

pp. 026461962110326

Author(s):

Su Ling Young ◽

Nathan Ng ◽

Ngee Jin Yap ◽

Zain Hussain ◽

Peter D Cackett

Keyword(s):

Low Vision ◽

Holistic Approach ◽

Depression Score ◽

Anxiety And Depression ◽

Macular Disease ◽

Global Pandemic ◽

Patient Reported ◽

One Stop ◽

End Stage ◽

Endothelial Growth Factor

Introduction: In 2017, the Royal College of Ophthalmologists UK published ‘The Way Forward’ describing the effects of the ageing UK population on clinical demand for macular conditions. Although one-stop clinics have become accepted standard practice for combined assessment and injections, there is little guidance regarding eventual discharge of patients, and practice varies between clinicians. In 2018, NHS Lothian started a multidisciplinary one-stop clinic involving an Ophthalmologist, a Medical Photographer, a specialist Low Vision Optometrist, and a Low Vision Counsellor. We aimed to detail our experiences of this novel multidisciplinary discharge clinic for advanced macular disease patients. We also aimed to assess patient-reported anxiety and depression outcomes following this clinic. Retrospective data on 60 patients who attended the clinic from August 2018 to January 2019 were collected and included in analysis. Average age at presentation to the clinic was 85.76 ± 8.18 years old and patients had been followed up in the macula clinic for a mean of 4.80 ± 2.43 years prior to attending the clinic. In all, 31 patients responded to a survey on anxiety and depression using the Hospital Anxiety and Depression score (HADS). Three (10%) of the patients reported scores abnormal for anxiety, and there were no abnormal scores for depression. The clinic provides a holistic approach for end-stage macular disease patients and reduces unnecessary macular anti–vascular endothelial growth factor treatments and clinic review appointments. This is especially important now during the coronavirus SARS-CoV-2 global pandemic. This provides significant benefits to capacity for delivery of clinical services and facilitates a safe and supported discharge for patients.

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