The effectiveness of mindfulness-based stress reduction (MBSR) in anxiety and depression in patients with multiple sclerosis (MS)

2017 ◽  
Vol 41 (S1) ◽  
pp. S409-S409 ◽  
Author(s):  
E. Alisaleh ◽  
S. Ghahari

ObjectiveThe main objective of the present study is to investigate effectiveness of mindfulness-based stress reduction in anxiety and depression in patients with multiple sclerosis.MethodsThis study is in kind of semi-experimental research in form of pretest–posttest pattern with control group. Statistical population of the study consists of all patients with multiple sclerosis referred to Iran MS Association by 2016. Sampling method in this study is available sampling and based on having inclusion criteria. Among depressed and anxiety patients 30 individuals were selected randomly and were classified in two groups with 15 people in each group. Experimental group was under mindfulness-based training on stress reduction for 8 sessions. Control group was also in waiting list. All patients in experimental and control groups fulfilled depression and anxiety inventories before and after intervention. Obtained data was analyzed using MANCOVA and in SPSS22 software.FindingObtained results show that there is significant difference between the two groups in terms of anxiety and depression after intervention (P < 0.001).ConclusionMindfulness-based stress reduction can help reduction of symptoms of anxiety and depression in patients with MS.Disclosure of interestThe authors have not supplied their declaration of competing interest.

2016 ◽  
Vol 9 (1) ◽  
pp. 28
Author(s):  
Shahrbanoo Ghahari ◽  
Nooshin Khademolreza ◽  
Fatemeh Sadeghi Poya ◽  
Siamak Ghasemnejad ◽  
Bahram Gheitarani ◽  
...  

Psychiatric disorders such as depression and anxiety are outputs of domestic violence and victims should be treated using medical and nonmedical treatment. The main purpose of this study is to investigate the effectiveness of mindfulness-based cognitive therapy in reducing anxiety and depression of women victims of domestic violence in Tehran. The study is an empirical research in kind of pretest-posttest plan with a control group. Statistical population consists of women victims of domestic violence in Tehran referred to several psychiatric clinics in Tehran for treatment by 2015. The statistical sample consists of 30 women selected randomly, who were placed into two groups, each group with 15 members. The experimental group was under the intervention of mindfulness-based cognitive therapy for 8 sessions and control group was in waiting list. Both groups, fulfilled Beck's Depression Inventory (BDI) and Spielberger's State-Trait Anxiety Inventory (STAI) in final step and end of treatment. Obtained data was analyzed using ANOVA and using SPSS22 software. The obtained results from the study show that there is a significant difference between two experimental and control groups in terms of depression and anxiety after mindfulness-based cognitive therapy intervention (p&lt;001). The obtained results from the study show that mindfulness-based cognitive therapy can affect the reduction of anxiety and depression of women victims of domestic violence.


Author(s):  
Shahrbanoo Ghahari ◽  
Nooshin Khademolreza ◽  
Fatemeh Sadeghi Poya ◽  
Siamak Ghasemnejad ◽  
Bahram Gheitarani ◽  
...  

Psychiatric disorders such as depression and anxiety are outputs of domestic violence and victims should be treated using medical and nonmedical treatment. The main purpose of this study is to investigate the effectiveness of mindfulness-based cognitive therapy in reducing anxiety and depression of women victims of domestic violence in Tehran. The study is an empirical research in kind of pretest-posttest plan with a control group. Statistical population consists of women victims of domestic violence in Tehran referred to several psychiatric clinics in Tehran for treatment by 2015. The statistical sample consists of 30 women selected randomly, who were placed into two groups, each group with 15 members. The experimental group was under the intervention of mindfulness-based cognitive therapy for 8 sessions and control group was in waiting list. Both groups, fulfilled Beck's Depression Inventory (BDI) and Spielberger's State-Trait Anxiety Inventory (STAI) in final step and end of treatment. Obtained data was analyzed using ANOVA and using SPSS22 software. The obtained results from the study show that there is a significant difference between two experimental and control groups in terms of depression and anxiety after mindfulness-based cognitive therapy intervention (p&lt;001). The obtained results from the study show that mindfulness-based cognitive therapy can affect the reduction of anxiety and depression of women victims of domestic violence.


2021 ◽  
Vol 38 (9) ◽  
pp. A4.2-A4
Author(s):  
Matthew Warren-James ◽  
Julie Hanson ◽  
Belinda Flanagan ◽  
Mary Katsikitis ◽  
Bill Lord

BackgroundWhilst there is evidence to suggest paramedics experience significant stress when working in the ambulance setting little is known about the experiences of first year paramedic students. This research aimed to: (i) identify whether levels of stress, anxiety and depression experienced by first year paramedic students changed after ambulance placement compared to a control group, and (ii) identify the main perceived and actual sources of stress around ambulance placement.MethodsA before-and-after quasi-experimental design was used to compare whether the experience of ambulance placement altered the levels of stress, anxiety and depression in an experimental group that attended an ambulance placement (n = 20) and the control group who did not (n = 10). Online surveys encompassing the Depression, Anxiety and Stress Scale (DASS-21) and qualitative questions about sources of stress were concurrently deployed to both the experimental and control groups before and after the ambulance placement. Participants were first year paramedic students working in Queensland Ambulance Service, Australia.ResultsThere was a significant reduction in levels of stress in participants after undertaking their first ambulance placement (Mdn = -4.00) when compared to a control group (Mdn = 0.00), U = 52.5, p = .035, n2 = 0.15. Responses to survey questions suggest anticipation about experiencing death and dying of patients was the most frequently reported stressor of student paramedics before undertaking ambulance placements, however insecurity about knowledge, competence and fear of failure was the most frequently experienced stressor reported after completing ambulance placements.ConclusionsThe findings from this study suggest that the fear of the unknown may be worse than the reality. Anticipatory stress is the foremost problem for first year paramedic students attending their first ambulance placement. Placement pre-briefing should focus on educational interventions to build knowledge and skills competency to reduce stress levels and fear of failure.


2020 ◽  
pp. 194589242096761
Author(s):  
Osman Kılıç ◽  
Aslı Şahin Yılmaz ◽  
Çağatay Oysu

Introduction The aim of this study is to investigate the effect of cigarette smoke on turbinate reactivity and mucociliary clearance (MCC) in passive smokers. Methods 60 adult patients (30 passive smokers and 30 healthy subjects as the control group) were recruited for this study. Following a questionnaire on passive smoke exposure, MCC measurement using the saccharin test was carried out to all participants. The baseline and after decongestant acoustic rhinometry values (MCA1, MCA2, VOL1, VOL2) were measured and the percentage changes between the two test values (ie; response to nasal decongestants = concha reactivity) were recorded. Results All 60 patients, including 37 women (61.7%) and 23 men (38.3%) were between 18–57 years of age . MCC’s average measurements were 11.13 minutes in the passive smokers group, 7.87 minutes in the control group, which was statistically significantly different (p < 0.05). There was a statistically significant difference between the passive smokers and control group for acoustic rhinometric measurement of the ratio of MCA2 and VOL2 values before and after decongestant application (p < 0.05). Discussion Passive smoking can damage the nasal mucosa at least as active smoking. The number of studies on this subject is limited. There are no studies in the literature showing the effect of cigarette smoke on the inferior turbinate mucosal response. In our study, the inferior turbinate decongestant capacity was found to be significantly decreased in the passive smokers compared to the control group. Conclusion As a result of cigarette exposure, the erectile function of the lower turbines may be impaired. The task of the ENT physicians is to warn the passive smokers in this regard.


2019 ◽  
Vol 39 (4) ◽  
pp. 245-255
Author(s):  
Yanny Octavia Sally Ride ◽  
Yusup Subagio Sutanto ◽  
Debree Septiawan

Background: Anxiolytic premedication can reduce anxiety, improving procedural tolerance, and reduce postbronchoscopic complications. There was ongoing debate about the safety of bronchoscopist-administered sedation. Alprazolam as a surgical premedication can reduce anxiety. Alprazolam can be used as an adjuvant analgesic, to reduce anxiety-related breathlessness, and to reduce coughing as adjuvant antitussive. The study aimed to evaluate the effectiveness of alprazolam in patients undergoing bronchoscopy. Methods: A clinical study with experimental quasi pre-post test control group design, using consecutive sampling was performed in patients with lung tumor undergoing bronchoscopy in dr.Moewardi Hospital from February to March 2019. The study subjects were divided in experimental (alprazolam) and control groups (without alprazolam). The Hospital Anxiety and Depression Scale (HADS), VAS for pain score, modified Borg score, and VAS for cough were measured in baseline, before, and after bronchoscopy. Results: Thirty two lung subjects were included in this study. The intervention groups showed decreased HADS score pre and post bronchoscopy (6.56±2.83 and 6.88±2.63), pain VAS scores (15.00±10.95 and 9.69±11.61), cough VAS score (11.56±8.89 and 27.19±17.89), and these were different significantly compared to control group. We found decreased mean of modified Borg in the study group though they were not significant compared to the control group. Conclusion: Alprazolam controlled anxiety, coughing, and pain in patients undergoing bronchoscopy. Alprazolam minimized breathlessness after bronchoscopy. (J Respir Indo. 2019; 39(4): 245-55)


2020 ◽  
Vol 19 ◽  
pp. 153473542094681
Author(s):  
Motahareh Mirmahmoodi ◽  
Parvin Mangalian ◽  
Atefeh Ahmadi ◽  
Mahlagha Dehghan

Introduction: Breast cancer is common among women and reduces their quality of life. The current study aimed to investigate the effectiveness of mindfulness-based stress reduction group counseling in alleviating psychological responses such as anxiety, depression, stress, and regulating laboratory tests including cortisol and C-reactive protein (CRP) in women with breast cancer. Methods: This randomized clinical trial was conducted based on convenience sampling. Participants were divided into 2 groups (control and intervention groups) with block randomization. The intervention group received mindfulness-based stress reduction group counseling during 8 weeks. The participants completed the Beck anxiety inventory, Beck-II depression inventory, and perceived stress scale before and after the intervention and their blood samples were taken to check their cortisol and CRP. Results: After the intervention, the MBSR group had significantly lower anxiety compared with the control group ( P < .001). No significant difference was found between the 2 groups in the reduction of perceived stress and depression ( P < .05). In addition, no significant difference was found between the 2 groups in CRP and cortisol levels after the intervention ( P > .05). Conclusion: The present study showed the effectiveness of mindfulness-based cognitive therapy in improving anxiety rather than the stress, depression, and inflammatory laboratory factors such as cortisol and CRP in women with breast cancer. Therefore, the psychological symptoms of these patients can be improved at different stages of treatment by providing this type of training.


2017 ◽  
Vol 5 (2) ◽  
pp. 98-104
Author(s):  
Dewi Pertiwi Dyah Kusudaryati ◽  
Siti Fatimah Muis ◽  
Laksmi Widajanti

Background : Zn supplementation on stunted children in multiple research get the result inconsistent concerning the effect of Zn on children’s growth.Objective : To examine the effect of Zn supplementation to the change in height for index among stunted children age between 24-36 months.Methods: The research design is randomized pretest posttest control group design. The total of thirty six stunted children are divided into two groups. The treatment group is received syrup with 20 mg ZnSO4 twice a week for three months. The control group received placebo without Zn. Height for age z score (HAZ) on WHO Child Growth 2006 is used to measure height for age index while dietary intake and infection diseases are used as confounding variables.Result : There is significant difference in HAZ before and after supplementation at treatment group (p<0.001) and control group (p<0.001). There is a significant difference of the change in HAZ between the treatment group and control group (p=0.006). Percentage Achievement of Energy, Protein, and Zn Dietary Allowance have significant difference between the treatment group and control group (p=0.009; p<0.001; p<0.001, respectively). The change in HAZ, Percentage Achievement of Energy, Protein, and Zn Dietary Allowance are higher in treatment group than control group. Duration of diarrhea (p=0.045) and morbidity (p=0.019) are lower in treatment group than control group. Conclusion : Zn Supplementation among stunted children have significant effect on the change in HAZ, dietary intake, and infection.


Medicina ◽  
2020 ◽  
Vol 56 (11) ◽  
pp. 596
Author(s):  
Greta Veličkaitė ◽  
Neringa Jucevičiūtė ◽  
Renata Balnytė ◽  
Ovidijus Laucius ◽  
Antanas Vaitkus

Background and objectives: Even though pain in multiple sclerosis (MS) patients is common and possibly associated with reduced quality of life, its exact prevalence and characteristics remain vaguely understood. We aimed to estimate the true extent of pain and its associations with quality of life in Lithuanian MS patients and to compare this data with that of a control group. Materials and Methods: Data were collected prospectively at the Department of Neurology, Lithuanian University of Health Sciences Kaunas Clinics. A face-to-face structured interview and a questionnaire were used to collect demographic and clinical data of the MS (n = 120) and control (n = 120) groups. The Expanded Disability Status Scale (EDSS) was used to quantify disability in the MS group. Scores ≥4/10 in the Douleur Neuropathique 4 questionnaire were classified as neuropathic pain. Patients were evaluated using the anxiety and depression subsets of the Hospital Anxiety and Depression Scale (HADS-A and HADS-D), the physical and mental component subsets of the Short Form-12 questionnaire (PSC-12 and MSC-12). Results: The MS and control groups did not differ in pain prevalence (76.7% vs. 65.9%, p = 0.064) or intensity. Lhermitte sign, lower limb, and face pain were more common in the MS group, whereas subjects in the control group were more often affected by lower back, neck, and joint pain. Neuropathic pain and pain lasting longer than 2 years were more common among pain-affected MS patients than among controls. MS patients with pain had higher EDSS, HADS-D, and HADS-A and lower PSC-12 scores than those without pain; however, no difference was found regarding the duration of MS or age. Males with MS and pain had higher MSC-12 and HADS-D scores in comparison to the same subset of females. Conclusions: Pain affects approximately three out of four patients with MS in Lithuania and is negatively associated with the mental and physical aspects of quality of life.


Author(s):  
Simin Jahani ◽  
Fatemeh Salari ◽  
Nasrin Elahi ◽  
Bahman Cheraghian

Objective: Findings suggest dissatisfaction of half of the cancer patients regarding pain and anxiety management. This study aimed to determine the effect of reflexology on the intensity of pain and anxiety among patients with metastatic cancer hospitalized inadulthematology ward.  Methods: In this study, the samples were selected from adult hematology ward in Baghaei 2 hospital in Ahwaz, Iran, according to the inclusion criteria. They were then assigned into treatment and control groups. In the treatment group, reflexology protocol was performed following manual reflexology method by Fr Josef Eugster based on Ingham method on the patient’s bed. In the control group, sole touching was used as the placebo. Reflexology was performed for three days, 30 min per day. Spielberger questionnaire were provided to the samples and completed in the first and third days, and Spielberger questionnaire was provided to the samples and completed. The data obtained from this study were then analyzed by SPSS 20.Results: The two groups did not show a significant difference in terms of demographic characteristics (p>0.05). Based on the obtained results, it was found that in the test group, there was a significant difference between the mean intensity of pain before and after the treatment across all 3 days as well as the mean anxiety of the 1st and 3rd days (p<0.05). However, in the control group, there was no significant difference in terms of mean pain intensity before and after the treatment across 3 days (p>0.05). No significant difference was observed between the mean anxiety of the 1st and 3rd days either (p>0.05).Conclusion: Considering the findings of this research, it can be concluded that reflexology has a positive effect on mitigating the intensity of pain and anxiety in metastatic cancer patients. Therefore, it is recommended that nurses employed in cancer centers benefit from the findings of this research to further help patients with cancer. It is also suggested that further research be conducted on the effect of reflexology on the pain and anxiety of other patients.


Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 516-521
Author(s):  
Sara Ami Ahmadi ◽  
Azin Kazemi ◽  
Mohammadmahdi Sabahi ◽  
Shahab Razipour ◽  
Arash Salehipour ◽  
...  

Introduction and Aim: Multiple Multiple sclerosis (MS) is a complex neurological condition  might emerge as a result ofcomplex combination of genetic risk factors with environmental triggers, including oxidative stress. in this study we aimed to evaluate the effects of oral Crocin on oxidative stress in patients with MS.  Materials and Methods: Adjunct to standard treatment, the Crocin group (20 patients) received 30-mg/day (15 mg twice daily) dose of Crocin and placebo group (20 patients) received for 4 weeks. Saliva and urine samples were collected to determine the levels of total antioxidant capacity (TAC), catalase activity (CAT), total thiol groups (TTG), lipid peroxidation (LPO), were measured at baseline and the end of the study.   Results: At baseline, there were no significant differences of LPO, TAC, CAT, and TTG of urine between the control and case groups. However, a significant difference was found after 4 weeks of Crocin-therapy in TTG,TAC and LPO (p<0.05) except in CAT activity (P>0.05). We found no deffrence in urinary TTG level and CAT activity in control group at the end of intervention (P>0.05), while TAC and LPO level were significantly different at the end of the study as compared with the beginning (P<0.05). Althugh, we found no significant difference in saliva LPO, TTG and TAC levels and the activity of CAT in case and control groups at first (p>0.05), Crocin administration have resulted in a significant increase in saliva TTG and TAC levels as well as CAT activity and markedly decrease in LPO level (p<0.05). Conclusion: According to the results of this study, Crocin can significantly reduce the several oxidative stress factors in MS patients and may contributes to attenuates the oxidative damages.


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