Herbal Products Containing Aristolochic Acids: A Call to Revisit the Context of Safety

2021 ◽  
pp. 100447
Author(s):  
Li Pei Ang ◽  
Pit Wei Ng ◽  
Yen Loong Lean ◽  
Vijay Kotra ◽  
Nurolaini Kifli ◽  
...  
Revista Fitos ◽  
2020 ◽  
Vol 14 (01) ◽  
pp. 38-44
Author(s):  
Antonio Jorge Ribeiro Da Silva ◽  
Maria Auxiliadora Coelho Kaplan ◽  
Celuta Sales Alviano ◽  
Daniela Sales Alviano Moreno ◽  
Davi Oliveira e Silva ◽  
...  

Aristolochic acids (AA) are phytochemicals found in plants of the genus Aristolochia belonging to the family Aristolochiaceae. These compounds bear a nitrophenanthrene carboxylic acid skeleton and are reported to be carcinogenic, mutagenic, and nephrotoxic. Sugar cane spirit infusions containing Aristolochia species are commonly used in Brazil as popular drinks, in total absence of scientific information. The presence aristolochic acids was confirmed in samples collected in popular markets of the city of Aracaju, Sergipe, Brazil. The aristolochic acids quantitative estimation was made in five samples of sugar cane spirit infusions obtained from different places of that city and were performed by high-performance liquid chromatography. The samples analyzed contained aristolochic acids I and II in concentrations ranging between 1.96 and 6.10 µg/ml for AA I and 2.22 and 11.55 µg/ml for AA II. The immediate banning of such popular drinks is recommended in view of the danger to ingest aristolochic acids, botanical products containing aristolochic acids or herbal products containing plants belonging to Aristolochiaceae family.          


Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
MJ Groot ◽  
MG Pikkemaat ◽  
WD Driessen van Lankveld
Keyword(s):  

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
AA Abdelgadir ◽  
L Boudesocque-Delaye ◽  
I Thery-Koné ◽  
A Gueiffier ◽  
EM Ahmed ◽  
...  

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Wahyuzan Wahyuzan ◽  
Lukmanul Hakim ◽  
Rahmat Afrizal ◽  
Asmeri Lamona ◽  
Khairuni Khairuni ◽  
...  

Traditional medicine in Indonesia has been known by the public before formal health services using modern medicine. Indonesia has many type of herbal plants which have medicinal properties including dadap (Erythrina orientalis). This study aims to utilized dadap herbal liniment by modifying heating in Vigin Cocanut Oil. The study conducted in the laboratory of Agricultural Product Processing using a Factorial Completely Randomized Design (CRD). The first factor is the addition of 250 ml (M1), 375 ml (m2), and 400 ml (M3) Virgin Cocanut Oil treatment. The second factor is the heating tim of 5 minutes (L1), 10 minutes (L2), and 15 minutes (L3). Observation variable consisted of yield, Specific gravity, and organoleptic test of aroma and colored. The result showed an average yield of 87.70-91.88%. The highest yield was found in the treatment of adding 400 ml Virgin Cocanut Oil and 15 minutes of heating time. The highest type of weight was found in the treatment of addition of 325 ml Virgin Cocanut Oil and 5 minutes heating time. Based on the organoleptic scent test, the everage penalist gives a like answer. Organoleptic colors of reudeuep herbal products is according to SNI number 06-23-2006.


Author(s):  
JASMEEN KAUR ◽  
◽  
MUNISH SINGLA ◽  
BALRAJ SAINI ◽  
GULSHAN BANSAL
Keyword(s):  

2018 ◽  
Vol 159 (18) ◽  
pp. 703-708
Author(s):  
Gábor Vasas

Abstract: More than 90% of herbal products and herbal medicines have been derived from higher plants recently, but due to independent circumstances, several photosynthetic microalgal species are in focus in this point of view. In the last 50 years, many carbohydrate-, peptide-, terpenoid-, alkaloid- and phenol-type components were described from algae because of the developing structural determination and analytical methods, algae mass production and also artificial algae technologies. At the same time, based partly on traditional causes and partly on the clinical and preclinical data of today, some dried products of algae are directly used as food supplements. Hereinafter, the historical background, economic significance and metabolic background of the mostly used microalgal species will be reviewed. The diverse metabolite production of these organisms will be demonstrated by some molecules with special bioactivity. Several preclinical and clinical studies will be described relating to the microalgal species Spirulina sp., Chlorella sp., Haematococcus sp. and Dunaliella sp. Orv Hetil. 2018; 159(18): 703–708.


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