A novel antibacterial agent based on AgNPs and Fe3O4 loaded chitin microspheres with peroxidase-like activity for synergistic antibacterial activity and wound-healing

2018 ◽  
Vol 552 (1-2) ◽  
pp. 277-287 ◽  
Author(s):  
Ningxiang Yu ◽  
Taimei Cai ◽  
Yong Sun ◽  
Chengjia Jiang ◽  
Hua Xiong ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Antibacterial Agent ◽  
Agent Based ◽  
Synergistic Antibacterial Activity

scholarly journals Antibacterial activity of Stichopus hermanii and Stichopus variegatus methanol extract

2020 ◽  
Vol 5 (2) ◽  
pp. 1-11
Author(s):  
Hendra Susanto ◽  
Mega Safithri ◽  
Kustiariyah Tarman
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Antibacterial Agent ◽  
Sea Cucumber ◽  
Freeze Drying ◽  
Methanol Extract ◽  
Diffusion Method ◽  
A Cell ◽  
Diabetic Wound Healing ◽  
Liquid Preparation

Since 500 years ago sea cucumber has been used as wound healing medicine. Sea cucumbers are thought to function as a cell growth factor and have the potential as an antibacterial agent. This study aims to determine whether the methanol extract of sea cucumber has antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa so that it can be used to help diabetic wound healing of people infected with the same bacteria. The extraction method used was maceration with methanol to dried frozen simplicia. The simplicia was obtained by freeze drying to liquid preparation of heated fresh sea cucumber. The antibacterial activity test was performed using well diffusion method. There were no any antibacterial activity found in the two methanol extracts of sea cucumber. Keywords: antibacterial agent, Stichopus hermanii, Stichopus variegatus

scholarly journals Synergistic antibacterial activity of surfactant free Ag–GO nanocomposites

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Muhammad Ashfaq Ahmad ◽  
Samia Aslam ◽  
Faiza Mustafa ◽  
Usman Arshad
Keyword(s):  
Antibacterial Activity ◽  
Ag Nanoparticles ◽  
Antibacterial Agent ◽  
Force Microscopy ◽  
E Coli ◽  
Atomic Force ◽  
Xrd Study ◽  
One Step ◽  
Ftir And Raman Spectroscopy ◽  
Synergistic Antibacterial Activity

AbstractGraphene oxide–silver (Ag–GO) nanocomposite has emerged as a vital antibacterial agent very recently. In this work, we report a facile one step route of Ag–GO nanocomposite formation excluding the aid of surfactants and reductants and was successfully applied to negative Escherichia Coli (E coli) to investigate antibacterial activity by varying doze concentration. The successful formation of Ag–GO nanocomposite via facile one step route was confirmed using Fourier transform infrared spectroscopy (FTIR) and Raman Spectroscopy. The absorption spectra (peak ~ 300 nm) for GO and the (peak ~ 420 nm) for silver nanoparticles were observed. XRD study confirmed the formation of Ag–GO nanocomposite while atomic force microscopy (AFM) showed crumbled GO sheets decorated with Ag nanoparticles. It was observed that the functional groups of GO facilitated the binding of Ag nanoparticles to GO network and enhanced the antibacterial activity of the nanocomposite.

Investigating the Synergistic Antibacterial Activity of Epiphytic Bacterial Polyketides and Biopolymer Alginates from Marine Microalgae

2021 ◽  
Vol 23 (10) ◽  
pp. 115-135
Author(s):  
Venkata Nagendra Prasad. B ◽  
◽  
Latha. D ◽  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Brown Seaweed ◽  
Wound Site ◽  
Padina Tetrastromatica ◽  
Biochemical Compounds ◽  
The Mean ◽  
Cell Migration And Proliferation ◽  
Synergistic Antibacterial Activity

The objective was framed to analyse the synergistic antibacterial activity and woundhealing ability of the developed polyketide-alginate polymers. Alginates were extracted from a brown seaweed Padina tetrastromatica and used as a synergistic compound along with bacterial polyketides. Polyketides and alginate polymer combinations were used against test bacteria to determine the synergistic antibacterial activity. A novel wound-healing film was developed using polyketide and alginates with synergistic concentrations and its degradability and wound-healing ability was investigated. The findings in the present research showed most significantly that, Staphylococcus aureus showed complete synergy with the mean MIC value of 0.03 μg/ml and with best FIC value of 0.24 (p<0.5). Degradation of developed films revealed that more moisture leads to more release of antibacterial alginate content at the wound site and hence more degradation. This was evident from the FESEM analysis. In vitro wound-healing assay revealed that the developed polyketide-alginate polymers exhibited cell migration and proliferation after 24th hour of incubation at 370C indicating the wound-healing abilities. Hence, it can be concluded that the biochemical compounds present in the developed polyketide-alginate polymers are considered highly significant in treating any types of wounds.

Antibacterial Activity of Thujaoccidentalis,ThujaorientalisandChamaecyparisobtusa

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Kyoung- Sun Seo ◽  
Seong Woo Jin ◽  
Seongkyu Choi ◽  
Kyeong Won Yun
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Antibacterial Agent ◽  
Methanol Extract ◽  
The Other ◽  
Diffusion Method ◽  
E Coli ◽  
Agar Diffusion ◽  
Agar Diffusion Method ◽  
Crude Methanol Extract

The antibacterial activity of three Cupressaceae plants (Thujaoccidentalis,ThujaorientalisandChamaecyparisobtusa) was tested against three bacteria using the agar diffusion method. The ether and ethylacetate fraction of crude methanol extract from the three plants showed potent antibacterial activity against the tested microorganisms. The result showed that Staphylococcus aureus revealed the most sensitivity among the tested bacteria. Thujaoccidentalisether fraction and Thujaorientalis hexane fraction exhibited the highest antibacterial activity against Staphylococcus aureus. E. coli was shown the highest MIC values compared to the other two tested bacteria, which indicates the lowest antibacterial activity against the bacterium. This study promises an interesting future for designing a potentially active antibacterial agent from the three Cupressaceae plants.

APPLICATIONS OF CHITOSAN-SULFATHIAZOLE AS ANTIMICROBIAL AGENT

2018 ◽  
Vol 28 (2) ◽  
pp. 429-432
Author(s):  
Dilyana Zvezdova
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Antimicrobial Agent ◽  
Defense Mechanisms ◽  
Solvent Casting ◽  
Casting Method ◽  
Gram Negative ◽  
Positively Charged

Chitosan, a hydrophilic biopolymer industrially obtained by N-deacetylation of chitin, can be applied as an antimicrobial agent. It highlights the applications of chitosan as an antimicrobial agent against fungi, bacteria, and viruses and as an elicitor of plant defense mechanisms. A series of novel chitosan-sulfathiazole nanocomposite (CSFZ) films were prepared by using solvent casting method for wound healing application. Fourier transform infrared spectroscopy (FTIR) was employed to ascertain the interaction between negatively charged sulfathiazole and positively charged chitosan. Moreover, the antibacterial activity of the films was investigated against gram positive and gram negative microorganisms. It was found that all CSFZ films showed good inhibitory activity against all the tested bacteria as compared to control. The above analysis suggested that the CSFZ films could be used as potential candidates for wound healing application.

A moisture balanced antibacterial dressing loaded with lysozyme possesses antibacterial activity and promotes wound healing

Soft Matter ◽  
2021 ◽  
Vol 17 (11) ◽  
pp. 3162-3173
Author(s):  
Ling Xiao ◽  
Wenqiang Ni ◽  
Xiaohong Zhao ◽  
Yicheng Guo ◽  
Xue Li ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Promote Wound Healing

An antibacterial moisture balanced dressing is designed to fight infection and promote wound healing.

A Fe3+-crosslinked pyrogallol-tethered gelatin adhesive hydrogel with antibacterial activity for wound healing

2020 ◽  
Vol 8 (11) ◽  
pp. 3164-3172 ◽  
Author(s):  
Ning Han ◽  
Ziyang Xu ◽  
Chunyan Cui ◽  
Yuan Li ◽  
Dongfei Zhang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Strong Adhesion ◽  
Mixing Method ◽  
Antibacterial Capacity

A tunicate-inspired gelatin-based hydrogel prepared by a simple mixing method, exhibits strong adhesion and antibacterial capacity, and facilitates wound healing.

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