P2-324: OPENNESS PERSONALITY TRAIT PREDICTS DELAYED VERBAL RECALL AT >1 YEAR FOLLOW-UP IN COGNITIVELY NORMAL OLDER ADULTS WITHOUT CURRENT OR LIFETIME HISTORY OF PSYCHIATRIC ILLNESS

ABSTRACT Background: Stroke is a leading cause of disability in developing countries. However, there are no studies assessing the impact of nonfatal strokes on mortality in rural areas of Latin America. Using a population-based, prospective cohort study, we aimed to assess the influence of nonfatal strokes on all-cause mortality in older adults living in an underserved rural setting. Methods: Deaths occurring during a 5-year period in Atahualpa residents aged ≥60 years were identified from overlapping sources. Tests for equality of survivor functions were used to estimate differences between observed and expected deaths for each covariate investigated. Cox proportional hazards models were used to estimate Kaplan–Meier survival curves of variables reaching significance in univariate analyses. Results: Of 437 individuals enrolled over 5 years, follow-up was achieved in 417 (95%), contributing 1776 years of follow-up (average 4.3 ± 1.3 years). Fifty-one deaths were detected, for an overall cumulative 5-year mortality rate of 12.2% (8.9%–15.6%). Being older than 70 years of age, having poor physical activity, edentulism, and history of a nonfatal stroke were related to mortality in univariate analyses. A fully adjusted Cox proportional hazards model showed that having history of a nonfatal stroke (P = 0.024) and being older than 70 years of age (P = 0.031) independently predicted mortality. In contrast, obesity was inversely correlated with mortality (P = 0.047). Conclusions: A nonfatal stroke and increasing age increase the risk of all-cause mortality in inhabitants of a remote rural village. The body mass index is inversely related to death (obesity paradox).

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Links Between Metabolic and Structural Changes in the Brain of Cognitively Normal Older Adults: A 4-Year Longitudinal Follow-Up

Frontiers in Aging Neuroscience ◽

10.3389/fnagi.2019.00015 ◽

2019 ◽

Vol 11 ◽

Cited By ~ 7

Author(s):

Christian-Alexandre Castellano ◽

Carol Hudon ◽

Etienne Croteau ◽

Mélanie Fortier ◽

Valérie St-Pierre ◽

...

Keyword(s):

Older Adults ◽

Structural Changes ◽

Cognitively Normal ◽

The Brain

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Predictors of ICU admission and long-term outcomes in overdose presentations to Emergency Department

Australasian Psychiatry ◽

10.1177/1039856219889317 ◽

2020 ◽

Vol 28 (1) ◽

pp. 75-79

Author(s):

Mark Savage ◽

Ross Kung ◽

Cameron Green ◽

Brandon Thia ◽

Dinushka Perera ◽

...

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Emergency Department ◽

Psychiatric Illness ◽

Atypical Antipsychotics ◽

Long Term Outcomes ◽

Icu Admission ◽

History Of

Objective: To describe the characteristics of patients presenting to an Emergency Department (ED) following overdoses; to identify risk factors for intensive care unit (ICU) admission among these patients; and to identify the rate of mortality and repeat overdose presentations over four years. Methods: Adult patients presenting to ED following drug overdose during 2014 were included. Data were collected from medical notes and hospital databases. Results: During the study period, 654 patients presented to ED 800 times following overdose. Seventy-eight (9.8%) resulted in ICU admission, and 59 (7.4%) required intubation; 57.2% had no history of overdose presentations, and 72.9% involved patients with known psychiatric illness. Overdose of atypical antipsychotics (AAP), age and history of prior overdose independently predicted ICU admission. A third of patients ( n = 196, 30%) had subsequent presentations to ED following overdose, in the four years from their index presentation, with an all-cause four-year mortality of 3.4% ( n = 22). Conclusion: A history of overdose, use of AAP and older age were risk factors for ICU admission following ED presentations. Over a third of patients had repeat overdose presentation in the four-year follow-up with a mortality of 3.4%.

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Risk of puerperal and non-puerperal recurrence of illness following bipolar affective puerperal (post-partum) psychosis

The British Journal of Psychiatry ◽

10.1192/bjp.186.3.258 ◽

2005 ◽

Vol 186 (3) ◽

pp. 258-259 ◽

Cited By ~ 84

Author(s):

Emma Robertson ◽

Ian Jones ◽

Sayeed Haque ◽

Roger Holder ◽

Nick Craddock

Keyword(s):

Mental Illness ◽

Value Of Information ◽

Psychiatric Illness ◽

Post Partum ◽

Positive Family History ◽

Psychotic Episode ◽

Clinical Value ◽

Puerperal Psychosis ◽

History Of

SummaryThe clinical value of information on the risk of future psychiatric illness in women who have experienced puerperal (post-partum) psychosis has been limited by inconsistencies in terminology and nosology. Here we report rates of subsequent puerperal and non-puerperal episodes, in a well-characterised sample of women diagnosed with clearly defined bipolar affective puerperal psychosis (n=103). Out of 54 women having further children, 31 (57%; 95% Cl 44–69) experienced an additional puerperal psychotic episode, and 64 of 103 women (62%; 95%Cl 52–71) experienced a non-puerperal affective episode during the follow-up period (mean duration 9 years). A history of bipolar episodes prior to the puerperal psychosis did not predict risk following subsequent pregnancies, but positive family history of mental illness predicted shorter time to non-puerperal relapse.

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Relationship Between Insomnia, Depression, and Mortality: A 12-Year Follow-Up of Older Adults in the Community

International Psychogeriatrics ◽

10.1017/s1041610200006414 ◽

2000 ◽

Vol 12 (3) ◽

pp. 295-306 ◽

Cited By ~ 120

Author(s):

Lena Mallon ◽

Jan-Erik Broman ◽

Jerker Hetta

Keyword(s):

Risk Factors ◽

Older Adults ◽

Natural History ◽

Confidence Interval ◽

Odds Ratio ◽

Death Rate ◽

Mortality Data ◽

Total Death ◽

History Of

The purpose of the study was to investigate the natural history of insomnia and its association with depression and mortality. In 1983, 1,870 randomly selected subjects aged 45–65 years answered a questionnaire on sleep and health. Of the 1,604 survivors in 1995, 1,244 (77.6%) answered a new questionnaire with almost identical questions. Mortality data were collected for the 266 subjects that had died during the follow-up period. Chronic insomnia was reported by 36.0% of women and 25.4% of men (χ2 = 9.7; p < .01). About 75% of subjects with insomnia at baseline continued to have insomnia at follow-up. Insomnia in women predicted subsequent depression (odds ratio [OR] = 4.1; 95% confidence interval [CI] 2.1–7.2) but was not related to mortality. In men, insomnia predicted mortality (OR = 1.7; 95% CI 1.2–2.3), but after adjustment for an array of possible risk factors, this association was no longer significant. Men with depression at baseline had an adjusted total death rate that was 1.9 times higher than in the nondepressed men (95% CI: 1.2–3.0).

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Death Ideation and Suicidal Ideation in a Community Sample Who Do Not Meet Criteria for Major Depression

Crisis ◽

10.1027/0227-5910/a000365 ◽

2016 ◽

Vol 37 (2) ◽

pp. 161-165 ◽

Cited By ~ 9

Author(s):

Jinhui Joo ◽

Seungyoung Hwang ◽

Joseph J. Gallo

Keyword(s):

Suicidal Ideation ◽

Social Withdrawal ◽

Community Sample ◽

General Health Questionnaire ◽

Population Based ◽

Depressive Illness ◽

Major Depressive ◽

Lifetime History ◽

History Of

Abstract. Background: Suicide is strongly associated with depression, but many without depression have thoughts of death. Aims: To characterize persons who did not meet criteria for depressive illness but endorsed death ideation or suicidal ideation over the course of a 10-year follow-up. Method: Subjects included 753 participants of the Baltimore sample of the Epidemiologic Catchment Area Program, a population-based 10-year follow-up survey, who neither met criteria for major depressive disorder nor reported death or suicidal ideation in 1994. Results: Persons with death ideation or suicidal ideation in 2004 were generally distressed as measured by the General Health Questionnaire. At baseline, both groups endorsed difficulty with concentration, feeling unhappy, and taking things hard. Functional problems such as social withdrawal were endorsed by both groups. Those with suicidal ideation had a longer lifetime history of social phobia. Persons with death ideation did not use more health services but sought help from persons in their social network. Conclusion: Thoughts of death are associated with distress even in persons who do not have depressive illness. This group of persons may have subclinical depressive symptoms that will not be detected by depression screening. Detection of these persons will require broadening our concept of persons at risk.

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Characteristics of Financial Exploitation in a Sample of Israeli Older Adults

Innovation in Aging ◽

10.1093/geroni/igab046.2827 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

pp. 770-770

Author(s):

Gali Weissberger ◽

S Duke Han ◽

Amit Shrira

Keyword(s):

Older Adults ◽

Depressive Symptoms ◽

Age Differences ◽

Service Providers ◽

Subjective Age ◽

Physical And Mental Health ◽

Older Adulthood ◽

Financial Exploitation ◽

History Of

Abstract Financial exploitation (FE) negatively affects wellbeing in older adulthood. However, characteristics of FE and its health correlates remain poorly understood. In this study, 138 Israeli older adults answered questions regarding FE history, and completed physical and mental health questionnaires. Of 138 participants, 23 reported a history of FE. FE participants were older (M birth year = 1950.35; sd = 9.65) than non-FE participants (M birth year = 1953.79; sd = 6.06; p = 0.028) and reported lower household income (p=0.001). Groups did not differ in education level or sex breakdown. The FE group reported older subjective age (p = 0.022), worse subjective cognition (p = 0.007), more depressive symptoms (p=0.002), and marginally higher anxiety symptoms (p = 0.099) than the non-FE group. Groups did not differ in reported levels of social support or number of medical conditions. When covarying for age, differences between groups in subjective cognition and depressive symptoms remained significant (ps ≤0.022), while subjective age differences became marginal (p = 0.07). The FE group responded to follow-up questions regarding FE experiences. Reported perpetrators included companies/businesses (most commonly reported, 30%), strangers, friends/neighbors, service providers, and family. Eleven reported losing 100 NIS to 10,000 NIS, and 10 reported losing 10,001 to over 100,000 NIS. Additionally, six FE participants reported that the FE is ongoing, and two reported additional FE experiences. Findings suggest that FE is related to mental and physical health of older adults. Findings also provide preliminary information regarding characteristics of FE in a sample of Israeli older adults.

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Predictors of Readmission Following Outpatient Treatment for Alcohol Use Disorder

Alcohol and Alcoholism ◽

10.1093/alcalc/agaa018 ◽

2020 ◽

Vol 55 (3) ◽

pp. 291-298

Author(s):

Emmanuel Mangkornkaew Hansen ◽

Anna Mejldal ◽

Anette Søgaard Nielsen

Keyword(s):

Alcohol Use ◽

Outpatient Treatment ◽

Psychiatric Illness ◽

Alcohol Use Disorder ◽

Addiction Severity Index ◽

Drop Out ◽

Younger Age ◽

History Of ◽

Index Treatment

Abstract Aims To identify predictors of readmission to outpatient treatment for alcohol use disorder (AUD) with a view to identifying underlying mechanisms for preventing relapse. Methods A consecutive clinical cohort of 2130 AUD outpatients treated between 1 January 2006 and 1 June 2016 was studied. Data were collected by means of the Addiction Severity Index upon treatment entry and at discharge. Outcome measures were readmission to outpatient treatment and time to readmission. Potential predictors were tested for significance using Cox Proportional Hazards multivariate analysis. Results A total of 22% were readmitted during the follow-up time. Patients readmitted within 1 year of treatment conclusion differed significantly from those not readmitted on age, cohabitation status and completion status of index treatment. Significant predictors of readmission during follow-up time were younger age (hazard ratio (HR) = 0.99, 95% confidence interval (CI), 0.98–1.00), history of psychiatric illness (HR = 1.24, 95% CI, 1.02–1.50), drop-out from index treatment (HR = 1.41, 95% CI, 1.15–1.72) and length of index treatment (HR = 1.02, 95% CI, 1.00–1.04). Conclusion Premature drop-out from treatment, a history of psychiatric illness, younger age and longer treatment episodes appear to be the most important predictors of readmission.

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