PTSD Symptom Heterogeneity and Alcohol-Related Outcomes in U.S. Military Veterans: Indirect Associations with Coping Strategies

2021 ◽  
pp. 102496
Author(s):  
Alexandra N. Palmisano ◽  
Sonya B. Norman ◽  
Kaitlyn E. Panza ◽  
Ismene L. Petrakis ◽  
Robert H. Pietrzak
2018 ◽  
Vol 229 ◽  
pp. 63-68 ◽  
Author(s):  
Sophia H.H. von Stockert ◽  
Eiko I. Fried ◽  
Cherie Armour ◽  
Robert H. Pietrzak

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0246990
Author(s):  
Marcel O. Bonn-Miller ◽  
Sue Sisley ◽  
Paula Riggs ◽  
Berra Yazar-Klosinski ◽  
Julie B. Wang ◽  
...  

Importance There is a pressing need for development of novel pharmacology for the treatment of Posttraumatic Stress Disorder (PTSD). Given increasing use of medical cannabis among US military veterans to self-treat PTSD, there is strong public interest in whether cannabis may be a safe and effective treatment for PTSD. Objective The aim of the present study was to collect preliminary data on the safety and potential efficacy of three active concentrations of smoked cannabis (i.e., High THC = approximately 12% THC and < 0.05% CBD; High CBD = 11% CBD and 0.50% THC; THC+CBD = approximately 7.9% THC and 8.1% CBD, and placebo = < 0.03% THC and < 0.01% CBD) compared to placebo in the treatment of PTSD among military veterans. Methods The study used a double-blind, cross-over design, where participants were randomly assigned to receive three weeks of either active treatment or placebo in Stage 1 (N = 80), and then were re-randomized after a 2-week washout period to receive one of the other three active treatments in Stage 2 (N = 74). The primary outcome measure was change in PTSD symptom severity from baseline to end of treatment in Stage 1. Results The study did not find a significant difference in change in PTSD symptom severity between the active cannabis concentrations and placebo by the end of Stage 1. All three active concentrations of smoked cannabis were generally well tolerated. Conclusions and relevance The present study is the first randomized placebo-controlled trial of smoked cannabis for PTSD. All treatment groups, including placebo, showed good tolerability and significant improvements in PTSD symptoms during three weeks of treatment, but no active treatment statistically outperformed placebo in this brief, preliminary trial. Additional well-controlled and adequately powered studies with cannabis suitable for FDA drug development are needed to determine whether smoked cannabis improves symptoms of PTSD. Trial registration Identifier: NCT02759185; ClinicalTrials.gov.


Author(s):  
Emily Hinton ◽  
Zachary Steel ◽  
Dominic Hilbrink ◽  
David Berle

Abstract Background: Drop-out is an important barrier in treating post-traumatic stress disorder (PTSD) with consequences that negatively impact clients, clinicians and mental health services as a whole. Anger is a common experience in people with PTSD and is more prevalent in military veterans. To date, no research has examined if anger may predict drop-out in military veterans or first responders. Aims: The present study aimed to determine the variables that predict drop-out among individuals receiving residential treatment for PTSD. Method: Ninety-five military veterans and first responders completed pre-treatment measures of PTSD symptom severity, depression, anxiety, anger, and demographic variables. Logistic regression analyses were used to determine if these variables predicted drop-out from treatment or patterns of attendance. Results: Female gender was predictive of drop-out. However, when analysed by occupation female gender was predictive of drop-out among first responders and younger age was predictive of drop-out in military participants. Anger, depression, anxiety and PTSD symptom severity were not predictive of drop-out in any of the analyses. No variables were found to predict attendance patterns (consistent or inconsistent) or early versus late drop-out from the programme. Conclusion: These results suggest that although anger is a relevant issue for treating PTSD, other factors may be more pertinent to drop-out, particularly in this sample. In contrast with other findings, female gender was predictive of drop-out in this study. This may indicate that in this sample, there are unique characteristics and possible interacting variables that warrant exploration in future research.


2017 ◽  
Vol 27 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Jessica L. Walton ◽  
Amanda M. Raines ◽  
Lisa-Ann J. Cuccurullo ◽  
Desirae N. Vidaurri ◽  
Margo C. Villarosa-Hurlocker ◽  
...  

2019 ◽  
Vol 28 (3) ◽  
pp. 660-672
Author(s):  
Suzanne H. Kimball ◽  
Toby Hamilton ◽  
Erin Benear ◽  
Jonathan Baldwin

Purpose The purpose of this study was to evaluate the emotional tone and verbal behavior of social media users who self-identified as having tinnitus and/or hyperacusis that caused self-described negative consequences on daily life or health. Research Design and Method An explanatory mixed-methods design was utilized. Two hundred “initial” and 200 “reply” Facebook posts were collected from members of a tinnitus group and a hyperacusis group. Data were analyzed via the LIWC 2015 software program and compared to typical bloggers. As this was an explanatory mixed-methods study, we used qualitative thematic analyses to explain, interpret, and illustrate the quantitative results. Results Overall, quantitative results indicated lower overall emotional tone for all categories (tinnitus and hyperacusis, initial and reply), which was mostly influenced by higher negative emotion. Higher levels of authenticity or truth were found in the hyperacusis sample but not in the tinnitus sample. Lower levels of clout (social standing) were indicated in all groups, and a lower level of analytical thinking style (concepts and complex categories rather than narratives) was found in the hyperacusis sample. Additional analysis of the language indicated higher levels of sadness and anxiety in all groups and lower levels of anger, particularly for initial replies. These data support prior findings indicating higher levels of anxiety and depression in this patient population based on the actual words in blog posts and not from self-report questionnaires. Qualitative results identified 3 major themes from both the tinnitus and hyperacusis texts: suffering, negative emotional tone, and coping strategies. Conclusions Results from this study suggest support for the predominant clinical view that patients with tinnitus and hyperacusis have higher levels of anxiety and depression than the general population. The extent of the suffering described and patterns of coping strategies suggest clinical practice patterns and the need for research in implementing improved practice plans.


2001 ◽  
Vol 30 (3) ◽  
pp. 159-163 ◽  
Author(s):  
Carsten Spitzer ◽  
Gerit Abraham ◽  
Konrad Reschke ◽  
Harald J. Freyberger
Keyword(s):  

Zusammenfassung. Theoretischer Hintergrund: Bisherige Selbstbeurteilungsinstrumente zur Abbildung posttraumatischer Belastungsstörungen (PTSD) berücksichtigen häufig den Symptomschweregrad nicht; außerdem setzen sie voraus, daß das Trauma bekannt sein muß. Fragestellung: Wir untersuchten die psychometrischen Eigenschaften eines Screeningverfahrens, das unabhängig von einem bekannten Trauma auch die Symptomintensität erfaßt. Methode: Die Modified PTSD Symptom Scale (MPSS) wurde bei 103 stationär psychiatrischen Patienten eingesetzt, die auch mit einem standardisierten Interview (DIA-X) untersucht wurden. Ergebnisse: Die Werte für Cronbachs Alpha lagen zwischen .88 und .94. Die Übereinstimmung zwischen MPSS-Verdachts- und DIA-X-Diagnosen lag zwischen 65% und 82%. Die innere Konsistenz ähnelt denen anderer Verfahren. Schlußfolgerungen: Für den klinischen Kontext erweist sich die MPSS dadurch vorteilhaft, daß sie die PTSD-Symptomatologie unabhängig von einem bekannten Trauma in ihrer Häufigkeit und ihrem Schweregrad erfaßt.


2003 ◽  
Vol 19 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Gisli H. Gudjonsson ◽  
Jon Fridrik Sigurdsson

Summary: The Gudjonsson Compliance Scale (GCS), the COPE Scale, and the Rosenberg Self-Esteem Scale were administered to 212 men and 212 women. Multiple regression of the test scores showed that low self-esteem and denial coping were the best predictors of compliance in both men and women. Significant sex differences emerged on all three scales, with women having lower self-esteem than men, being more compliant, and using different coping strategies when confronted with a stressful situation. The sex difference in compliance was mediated by differences in self-esteem between men and women.


2018 ◽  
Vol 34 (5) ◽  
pp. 352-360 ◽  
Author(s):  
Silvia Bonino ◽  
Federica Graziano ◽  
Martina Borghi ◽  
Davide Marengo ◽  
Giorgia Molinengo ◽  
...  

Abstract. This research developed a new scale to evaluate Self-Efficacy in Multiple Sclerosis (SEMS). The aim of this study was to investigate dimensionality, item functioning, measurement invariance, and concurrent validity of the SEMS scale. Data were collected from 203 multiple sclerosis (MS) patients (mean age, 39.5 years; 66% women; 95% having a relapsing remitting form of MS). Fifteen items of the SEMS scale were submitted to patients along with measures of psychological well-being, sense of coherence, depression, and coping strategies. Data underwent Rasch analysis and correlation analysis. Rasch analysis indicates the SEMS as a multidimensional construct characterized by two correlated dimensions: goal setting and symptom management, with satisfactory reliability coefficients. Overall, the 15 items reported acceptable fit statistics; the scale demonstrated measurement invariance (with respect to gender and disease duration) and good concurrent validity (positive correlations with psychological well-being, sense of coherence, and coping strategies and negative correlations with depression). Preliminary evidence suggests that SEMS is a psychometrically sound measure to evaluate perceived self-efficacy of MS patients with moderate disability, and it would be a valuable instrument for both research and clinical applications.


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