Effect of the vinegar-process on chemical compositions and biological activities of Euphorbia kansui: A review

Nowadays, cancer treatment has been a big challenge to healthcare systems. Most of clinical anti-cancer therapies are toxic and cause adverse effects to human body. Therefore, current trend in science is seeking and screening of natural compounds which possess antineoplastic activities to utilize in treatment. Uvaria L. - Annonaceae includes approximately 175 species spreading over tropical areas of Asia, Australia, Africa and America. Studies on chemical compositions and pharmacological effects of Uvaria showed that several compound classes in this genus such as alkaloid, flavonoid, cyclohexen derivaties, acetogenin, steroid, terpenoid, etc. indicate considerable biological activities, for example anti-tumor, anti-cancer, antibacterial, antifungal, antioxidant, etc. Specifically, anti-cancer activity of fractions of extract and pure isolated compounds stands out for cytotoxicity against many cancer cell lines. This study provides an overview of anti-cancer activity of Uvaria and suggests a potential for further studies on seeking and developing novel anti-cancer compounds. Key words: Anti-cancer, Uvaria.

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Phytochemical Analysis and Potential Biological Activities of Essential Oil from Rice Leaf

Molecules ◽

10.3390/molecules24030546 ◽

2019 ◽

Vol 24 (3) ◽

pp. 546 ◽

Cited By ~ 3

Author(s):

Truong Minh ◽

Tran Xuan ◽

Truong Van ◽

Yusuf Andriana ◽

Tran Viet ◽

...

Keyword(s):

Mass Spectrometry ◽

Essential Oil ◽

Atmospheric Pressure Chemical Ionization ◽

Biological Activities ◽

Methyl Ricinoleate ◽

Gas Chromatography Mass Spectrometry ◽

Phytochemical Analysis ◽

Chemical Compositions ◽

Rice Leaf ◽

Rice Leaves

Although many investigations on phytochemicals in rice plant parts and root exudates have been conducted, information on the chemical profile of essential oil (EO) and potent biological activities has been limited. In this study, chemical compositions of rice leaf EO and in vitro biological activities were investigated. From 1.5 kg of fresh rice leaves, an amount of 20 mg EO was obtained by distillation and analyzed by gas chromatography-mass spectrometry (GC-MS), electrospray ionization (ESI), and atmospheric pressure chemical ionization (APCI) to reveal the presence of twelve volatile constituents, of which methyl ricinoleate (27.86%) was the principal compound, followed by palmitic acid (17.34%), and linolenic acid (11.16%), while 2-pentadecanone was the least (2.13%). Two phytoalexin momilactones A and B were first time identified in EO using ultra-performance liquid chromatography coupled with electrospray mass spectrometry (UPLC/ESI-MS) (9.80 and 4.93 ng/g fresh weight, respectively), which accounted for 7.35% and 3.70% of the EO, respectively. The assays of DPPH (IC50 = 73.1 µg/mL), ABTS (IC50 = 198.3 µg/mL), FRAP (IC50 = 700.8 µg/mL) and β-carotene oxidation (LPI = 79%) revealed that EO possessed an excellent antioxidant activity. The xanthine oxidase assay indicated that the anti-hyperuricemia potential was in a moderate level (IC50 = 526 µg/mL) as compared with the standard allopurinol. The EO exerted potent inhibition on growth of Raphanus sativus, Lactuca sativa, and two noxious weeds Echinochloa crus-galli, and Bidens pilosa, but in contrast, the growth of rice seedlings was promoted. Among the examined plants, the growth of the E. crus-galli root was the most inhibited, proposing that constituents found in EO may have potential for the control of the problematic paddy weed E. crus-galli. It was found that the EO of rice leaves contained rich phytochemicals, which were potent in antioxidants and gout treatment, as well as weed management. Findings of this study highlighted the potential value of rice leaves, which may provide extra benefits for rice farmers.

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Chemical composition, antimicrobial, antioxidative and anticholinesterase activity of Satureja Montana L. ssp montana essential oil

Open Life Sciences ◽

10.2478/s11535-014-0298-x ◽

2014 ◽

Vol 9 (7) ◽

pp. 668-677 ◽

Cited By ~ 5

Author(s):

Tatjana Mihajilov-Krstev ◽

Dragan Radnović ◽

Dušanka Kitić ◽

Vesna Jovanović ◽

Violeta Mitić ◽

...

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Human Serum ◽

Biological Activities ◽

Serum Cholinesterase ◽

Health Improvement ◽

Chemical Compositions ◽

Bacterial Strains ◽

Antimicrobial Potential ◽

Satureja Montana

AbstractThe present study investigates the chemical compositions of three Satureja montana L. ssp montana essential oils and correlates chemical variability with biological activities. GC/MS analysis showed that with an increase in altitude (100–500–800 m), a higher content of linalool, terpinen-4-ol and cis-sabinene hydrate was found, while the percentage of phenolic compounds, thymol and carvacrol decreased. Antimicrobial activity of the essential oils was tested against 7 fungal and 23 bacterial strains. The essential oil characterized by the highest content of phenols and alcohols exhibited the highest antimicrobial potential. The correlation analysis showed that the major carriers of the obtained antioxidant activity are oxygenated monoterpenes. All essential oils inhibited human serum cholinesterase activity. High antimicrobial potential, together with moderate antioxidant capacity and strong inhibition of human serum cholinesterase, classifies S. montana essential oil as a natural source of compounds that can be used in the treatment of foodborne and neurological diseases, wound and other infections, as well as for general health improvement.

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Antimicrobial Efficiency of Essential Oils from Traditional Medicinal Plants of Asir Region, Saudi Arabia over Drug Resistant Isolates

10.20944/preprints201810.0236.v1 ◽

2018 ◽

Author(s):

Ismail M. Helal ◽

Ashraf El-Bessoumy ◽

Erwah Al-Bataineh ◽

Martin R.P. Joseph ◽

Parassena Rajagopalan ◽

...

Keyword(s):

Saudi Arabia ◽

Essential Oils ◽

Streptococcus Pyogenes ◽

Biological Activities ◽

Ocimum Basilicum ◽

Antimicrobial Efficacy ◽

Chemical Compositions ◽

Drug Resistant ◽

Origanum Vulgare ◽

Asir Region

Antimicrobial resistance (AMR) is a recurring global problem, which constantly demands new antimicrobial compounds to challenge the resistance. It is well known that essential oils (EOs) have been known for biological activities including antimicrobial properties. In this study, EOs from seven aromatic plants of Asir region of southwestern Saudi Arabia were tested for their antimicrobial efficacy against four drug resistant pathogenic bacterial isolates (Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli and Streptococcus typhimurium) and one fungal isolate (Candida albicans). Chemical compositions of EOs were determined by Gas chromatography-Mass Spectrometry (GC-MS). The results revealed that EOs from Mentha cervina, Ocimum basilicum and Origanum vulgare proved most active against all isolates with inhibitory zone range between17 to 45 mm.  The lowest minimum inhibitory concentration (MIC) of 0.025mg/ml was observed for Staph. aureus and Streptococcus pyogenes with EO of Origanum vulgare. All the three EOs showed significant anti candida activity. Together form the results the EOs from Mentha cervina, Ocimum basilicum and Origanum vulgare demonstrated a significant antimicrobial efficacy against drug resistant microorganisms.

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Chemical Compositions, Phytotoxicity, and Biological Activities of Acorus Calamus Essential Oils from Nepal

Natural Product Communications ◽

10.1177/1934578x1300800839 ◽

2013 ◽

Vol 8 (8) ◽

pp. 1934578X1300800 ◽

Cited By ~ 2

Author(s):

Prabodh Satyal ◽

Prajwal Paudel ◽

Ambika Poudel ◽

Noura S. Dosoky ◽

Debra M. Moriarity ◽

...

Keyword(s):

Antifungal Activity ◽

Aspergillus Niger ◽

Seed Germination ◽

Essential Oils ◽

Brine Shrimp ◽

Biological Activities ◽

Acorus Calamus ◽

Chemical Compositions ◽

Seedling Growth Inhibition ◽

Mcf 7

Four essential oils from the leaf (P23) and rhizomes (P19, P22, P24) of Acorus calamus L., collected from various parts of Nepal, were obtained by hydrodistillation and analyzed by GC-MS. From a total of 61 peaks, 57 compounds were identified among the four essential oils accounting for 94.3%, 96.2%, 97.6%, and 94.1% of the oils, respectively. All of the essential oils were dominated by ( Z)-asarone (78.1%–86.9%). The essential oils also contained ( E)-asarone (1.9%–9.9%) and small amounts of γ-asarone (2.0–2.3%), ( Z)-methyl isoeugenol (1.5–2.0%), and linalool (0.2–4.3%). Allelopathic testing of the rhizome oil showed inhibition of seed germination of Lactuca sativa and Lolium perenne with IC50 values of 450 and 737 μg/mL, respectively. The rhizome essential oil demonstrated stronger seedling growth inhibition of L. perenne than of L. sativa, however. The rhizome oil also showed notable brine shrimp lethality ( LC50 = 9.48 μg/mL), cytotoxic activity (92.2% kill on MCF-7 cells at 100 μg/mL), and antifungal activity against Aspergillus niger (MIC = 19.5 μg/mL).

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The Difference of Chemical Components and Biological Activities of the Raw Products slices and the Wine Steam-Processed Product from Cistanche deserticola

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2019/2167947 ◽

2019 ◽

Vol 2019 ◽

pp. 1-10 ◽

Cited By ~ 2

Author(s):

Ying Zhang ◽

Yuewu Wang ◽

Song Yang ◽

Yunfeng Xiao ◽

Haibin Guan ◽

...

Keyword(s):

Quantitative Analysis ◽

Biological Activities ◽

Biological Effects ◽

Chinese Herb ◽

Principal Component ◽

Deficiency Syndrome ◽

Chemical Components ◽

Chemical Compositions ◽

Kidney Deficiency ◽

Cistanche Deserticola

As a well-known Chinese herb medicine, the Cistanche deserticola has been used for the treatment of kidney deficiency syndrome in China for thousands of years. Both the raw product of Cistanche deserticola slices (RCD) and its Wine Steam-Processed Product (WSCD) are used clinically for different effects. In this study, the influences of steaming process with wine (SPW) from Cistanche deserticola on chemical compositions and biological effects were investigated. The principal component analysis (PCA) and quantitative analysis were used to study the differences of the chemical compositions. The effects of nourishing kidney were also investigated to compare the differences between the RCD and the WSCD. The PCA results indicated that the obvious separation was achieved in the RCD and WSCD. The results of quantitative analysis showed that the WSCD has higher amounts of total polysaccharides, total PhGs, isoacteoside, and osmanthuside B than RCD, while the content of 2′-acetylacteoside and acteoside decreased after the SPW. The comparison of RCD and WSCD on biological activities showed that both could restore the level of sex hormone in the model of kidney-yang deficiency and improve the antioxidant effect. The WSCD were much better in increasing the viscera weight of kidney and seminal vesicle. The results indicated that SPW changed its chemical components and enhanced its biological activities.

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Antimicrobial Efficiency of Essential Oils from Traditional Medicinal Plants of Asir Region, Saudi Arabia, over Drug Resistant Isolates

BioMed Research International ◽

10.1155/2019/8928306 ◽

2019 ◽

Vol 2019 ◽

pp. 1-9 ◽

Cited By ~ 13

Author(s):

Ismail M. Helal ◽

Ashraf El-Bessoumy ◽

Erwa Al-Bataineh ◽

Martin R. P. Joseph ◽

Prasanna Rajagopalan ◽

...

Keyword(s):

Saudi Arabia ◽

Essential Oils ◽

Streptococcus Pyogenes ◽

Biological Activities ◽

Ocimum Basilicum ◽

Antimicrobial Efficacy ◽

Chemical Compositions ◽

Drug Resistant ◽

Origanum Vulgare ◽

Asir Region

Antimicrobial resistance (AMR) is a recurring global problem, which constantly demands new antimicrobial compounds to challenge the resistance. It is well known that essential oils (EOs) have been known for biological activities including antimicrobial properties. In this study, EOs from seven aromatic plants of Asir region of southwestern Saudi Arabia were tested for their antimicrobial efficacy against four drug resistant pathogenic bacterial isolates (Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, and Streptococcus typhimurium) and one fungal isolate (Candida albicans). Chemical compositions of EOs were determined by gas chromatography-mass spectrometry (GC-MS). The results revealed that EOs from Mentha cervina, Ocimum basilicum, and Origanum vulgare proved most active against all isolates with inhibitory zone range between 17 and 45 mm. The lowest minimum inhibitory concentration (MIC) of 0.025mg/ml was observed for Staph. aureus and Streptococcus pyogenes with EO of Origanum vulgare. All the three EOs showed significant anticandida activity. The results related to EOs from Mentha cervina, Ocimum basilicum, and Origanum vulgare demonstrated significant antimicrobial efficacy against drug resistant microorganisms.

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Chemical Compositions by Using LC-MS/MS and GC-MS and Biological Activities of Sedum sediforme (Jacq.) Pau

Journal of Agricultural and Food Chemistry ◽

10.1021/jf500067q ◽

2014 ◽

Vol 62 (20) ◽

pp. 4601-4609 ◽

Cited By ~ 30

Author(s):

Abdulselam Ertaş ◽

Mehmet Boğa ◽

Mustafa Abdullah Yılmaz ◽

Yeter Yeşil ◽

Nesrin Haşimi ◽

...

Keyword(s):

Biological Activities ◽

Chemical Compositions

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Advances in studies on chemical compositions of Atractylodes lancea and their biological activities

China Journal of Chinese Materia Medica ◽

10.4268/cjcmm20162104 ◽

2016 ◽

Keyword(s):

Biological Activities ◽

Chemical Compositions ◽

Atractylodes Lancea

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Compositions and Biological Activities of Essential Oils of Kadsura longepedunculata and Schisandra sphenanthera

The American Journal of Chinese Medicine ◽

10.1142/s0192415x07004874 ◽

2007 ◽

Vol 35 (02) ◽

pp. 353-364 ◽

Cited By ~ 13

Author(s):

Lei Song ◽

Jie-Ying Ding ◽

Cui Tang ◽

Chun-Hua Yin

Keyword(s):

Essential Oils ◽

Antioxidant Activities ◽

Biological Activities ◽

Liver Homogenate ◽

Reducing Power ◽

Antimicrobial Activities ◽

Dilution Method ◽

Chemical Compositions ◽

Dependent Manner ◽

Schisandra Sphenanthera

The chemical compositions, antimicrobial activities, antioxidant activities and cytotoxicities of the essential oils isolated from the root of Kadsura longepedunculata Finet et Gagnep (KLREO) and the fruit of Schisandra sphenanthera Rehd. et Wills. (SSFEO) were investigated.The analyses of gas chromatography-mass spectrometry (GC-MS) showed that cadinane type compounds and their derivatives were rich in both oils (54.2% and 39.7%, respectively) and δ-cadinene was the major component of both oils (13.8% and 25.6%, respectively). The antimicrobial activities of both oils were evaluated against five microorganisms with the disc diffusion and the broth micro-dilution method. Results showed that Gram-positive bacteria were more sensitive to both oils than Gram-negative bacteria and the yeast. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the oil of KLREO were lower than those of SSFEO, indicating that the former possessed slightly stronger antibacterial capability than the latter. The reducing power and lipid peroxidation assays were employed to study the potential antioxidant activities of both oils. Both oils remarkably decreased the content of malondialdehyde (MDA) in rat liver homogenate in a dose dependent manner. The antioxidant activities of KLREO appeared to be more potent than that of SSFEO. The oils of KLREO and SSFEO exhibited concentration-dependent cytotoxicities and were proved to be toxic to HepG2 cells with IC50 of 147 and 189 μg/ml, respectively.

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