Selection of broad-spectrum aptamer and its application in fabrication of aptasensor for detection of aminoglycoside antibiotics residues in milk

2021 ◽  
pp. 130959
Author(s):  
Fengling Yue ◽  
He Li ◽  
Qianqian Kong ◽  
Jing Liu ◽  
Guangxian Wang ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Aminoglycoside Antibiotics ◽  
Antibiotics Residues ◽  
Selection Of

The Study of Bacillus Subtils Antimicrobial Activity on Some of the Pathological Isolates

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Hussein A Kadhum ◽  
Thualfakar H Hasan2
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Bacterial Growth ◽  
Broad Spectrum ◽  
Inhibitory Activity ◽  
Bacterial Pathogens ◽  
Inhibitory Ability ◽  
Selection Of

The study involved the selection of two isolates from Bacillus subtilis to investigate their inhibitory activity against some bacterial pathogens. B sub-bacteria were found to have a broad spectrum against test bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. They were about 23-30 mm and less against Klebsiella sp. The sensitivity of some antibodies was tested on the test samples. The results showed that the inhibitory ability of bacterial growth in the test samples using B. subtilis extract was more effective than the antibiotics used.

Structural hybridization of three aminoglycoside antibiotics yields a potent broad-spectrum bactericide that eludes bacterial resistance enzymes

MedChemComm ◽  
2016 ◽  
Vol 7 (1) ◽  
pp. 170-176 ◽  
Author(s):  
Juan Pablo Maianti ◽  
Stephen Hanessian
Keyword(s):  
Broad Spectrum ◽  
Bacterial Resistance ◽  
Structural Features ◽  
Aminoglycoside Antibiotics ◽  
Enzymatic Modification ◽  
X Ray

Systematically blending structural features from obsolete aminoglycosides gleaned from X-ray co-crystal models rendered a promising antibiotic inert to enzymatic modification.

Determination of aminoglycoside antibiotics in biological fluids: a review.

1979 ◽  
Vol 25 (8) ◽  
pp. 1361-1367 ◽  
Author(s):  
S K Maitra ◽  
T T Yoshikawa ◽  
L B Guze ◽  
M C Schotz
Keyword(s):  
Clinical Laboratory ◽  
Biological Fluids ◽  
Aminoglycoside Antibiotics ◽  
Selection Of

Abstract We describe current procedures for measuring aminoglycoside antibiotics. Although many of these techniques are suitable for clinical adaptation, selection of a method for use in a clinical laboratory will depend on the budget and availability of equipment and expertise.

scholarly journals Aminoglycoside Antibiotics Inhibit Mycobacteriophage Infection

Antibiotics ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 714 ◽  
Author(s):  
Zheng Jiang ◽  
Junwei Wei ◽  
Yunxiang Liang ◽  
Nan Peng ◽  
Yingjun Li
Keyword(s):  
Antibiotic Resistance ◽  
Mycobacterium Tuberculosis ◽  
Structural Analysis ◽  
Global Health ◽  
Broad Spectrum ◽  
Phage Therapy ◽  
Amino Sugar ◽  
Aminoglycoside Antibiotics ◽  
Phage Infection ◽  
Drug Resistant

Antibiotic resistance is becoming the biggest threat to global health. At the same time, phage therapy is witnessing a return of interest. The therapeutic use of bacteriophages that infect and kill bacteria is a suitable strategy to combat antibiotic resistance. Furthermore, bacteriophages are increasingly used in combination with standard antibiotics against drug-resistant pathogens. Interestingly, we found that the engineered mycobacteriophage phAE159 and natural phage D29 cannot infect the Mycobacterium tuberculosis in the presence of kanamycin, hygromycin or streptomycin, but the phage infection was not affected in the presence of spectinomycin. Based on a series of studies and structural analysis of the above four aminoglycoside antibiotics, it could be speculated that the amino sugar group of aminoglycoside might selectively inhibit mycobacteriophage DNA replication. Our discovery that broad-spectrum antibiotics inhibit phage infection is of great value. This study will provide guidance for people to combine phage and antibiotics to treat M. tuberculosis.

Selecting International Freight Forwarders: An Expert Systems Application

1993 ◽  
Vol 23 (3) ◽  
pp. 11-21 ◽  
Author(s):  
Aysegül Özsomer ◽  
Michel Mitri ◽  
S. Tamer Cavusgil
Keyword(s):  
Artificial Intelligence ◽  
Expert Systems ◽  
Competitive Advantage ◽  
Broad Spectrum ◽  
International Marketing ◽  
Decision Makers ◽  
Third Party ◽  
Foreign Markets ◽  
Freight Forwarder ◽  
Selection Of

The recent changes in the international forwarding environment have witnessed the emergence of “new forms” of forwarders incorporating a broad spectrum of services under one roof. Such total logistics companies are becoming a critical third party in obtaining a competitive advantage in foreign markets. Hence, the evaluation and selection of an international freight forwarder is no longer a simple operational decision but a strategic one. Presents and explains an expert systems tool to assist decision makers in selecting the freight forwarder which fits their needs best. The system, called FREIGHT, brings together international marketing, logistics and artificial intelligence knowledge.

Selection of appropriate preparation techniques

1989 ◽  
Vol 4 ◽  
pp. 24-29
Author(s):  
Rodney M. Feldmann
Keyword(s):  
Broad Spectrum ◽  
Fossil Specimen ◽  
Extreme Care ◽  
Preparation Techniques ◽  
Selection Of

Preparation of fossils, as well as their subsequent study and illustration, can be accomplished utilizing a broad spectrum of techniques. Even though some of the procedures require nothing more complex than hammer and chisel, such work can be extremely demanding. Regardless of the techniques employed, the worker must exercise extreme care and patience in performing this work. A fossil specimen simply cannot be replaced!

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