GEONs API fingerprint project: Selection of analytical techniques for clustering of sildenafil citrate API samples

Kabupaten Bantul meraih prestasi tingkat nasional di tahun 2008 yakni memperoleh penghargaan dalam KPPOD Award. Penghargaan yang diperoleh menjadi awal yang baik bagi Kabupaten Bantul dalam memperbaiki iklim penanaman modal. Tujuan dari penelitian ini untuk mengidentifikasi dan menganalisis distribusi keruangan penanaman modal dan pengaruh karakteristik wilayah terhadap pemilihan lokasi penanaman modal. Teknik analisis yang digunakan adalah analisis deskriptif, analisis tetangga terdekat, dan analisis regresi berganda. Berdasarkan hasil kajian dapat disimpulkan bahwa distribusi keruangan penanaman modal di Kabupaten Bantul terdistribusi di 10 kecamatan, sedangkan 7 kecamatan lainnya belum menjadi destinasi penanaman modal. Untuk lokasi perusahaan penanaman modal membentuk pola dispersed atau merata dengan nilai R sebesar 5,920887 (R>1). Sebagian dari lokasi penanaman modal berada di tepi jalan raya. Pemilihan lokasi penanaman modal di Kabupaten Bantul dipengaruhi oleh faktor daya tarik karakteristik wilayah seperti pertumbuhan ekonomi dan jumlah objek wisata. Bantul Regency won the national award of KPPOD in 2008. That award was a good commencement to improve Bantul Regency’s investment climate. The aims of this research were to identify and analyse the spatial distribution of investment and the effect of regional characteristics on the selection of investment site. The analytical techniques used in the research are descriptive analysis, nearest neighbour analysis, and multiple regression analysis. Based on the analysis, it can be concluded that distribution of investment in Bantul Regency distributed in 10 sub-districts, while 7 others are not yet be destination of investment. For the location of investment firms forms a dispersed pattern with R value 5,920887 (R>1). Some investment firm are located on the edge of highway. The selection of investment sites in Bantul regency is affected by the attraction factors of the region characteristics such as economic growth and number of tourism objects.

Download Full-text

THE INFLUENCE OF RECRUITMENT AND SELECTION PROCESS ON TECHNICAL EMPLOYEE PERFORMANCE IN PT. TELKOM AKSES NORTH SURABAYA

Ekspektra Jurnal Bisnis dan Manajemen ◽

10.25139/ekt.v4i1.2588 ◽

2020 ◽

Vol 4 (1) ◽

pp. 84-93

Author(s):

Agustiawan Djoko Baruno ◽

Leny Novita Permatasari

Keyword(s):

Selection Process ◽

Employee Performance ◽

Selection Effect ◽

Analytical Techniques ◽

Partial Least Square ◽

Least Square ◽

Primary Data ◽

P Values ◽

Recruitment And Selection ◽

Selection Of

This research aims to analyze the influence of the process of recruitment and selection simultaneously as well as partially against employee performance support. In this study using a type of associative methods and quantitative data primary data sources by using the instrument of the questionnaire. The population in this research is the employee technician PT. Telkom Akses Surabaya Utara as many as 56 respondents.Sampling technique used was saturated samples or often called as well with a sample of the total. Analytical techniques used in this research is the Partial Least Square (PLS) includes test convergen validity, discriminan validity, composite realibility, cronch alpha, R- square, simulan test (test F) and partial test (test T). The results of the analysis explains that the process of recruitment and selection effect simultaneously against the performance of the employee, this is indicated by the value of the count of 40.991 F is greater than F table 4.02 and significance value (S ig) 0.000 smaller than 0.05 and the process of recruitment of influential partially against the performance of the employee, this is shown by the value T calculate of 3.024 is greater than 1.96 table T and value its significance (P values) 0.003 smaller than 0.05. As well as a selection of influential partially against the performance of the employee, this is shown by the value T calculate of 2.856 is greater than 1.96 table T and value its significance (P values) 0.004 smaller than 0.05

Download Full-text

Synthesis and ADMET Study of Some 1, 8-Naphthyidine and Quinoline 3-Carboxylic Acid Derivatives

International Journal for Research in Applied Science and Engineering Technology ◽

10.22214/ijraset.2021.39142 ◽

2021 ◽

Vol 9 (11) ◽

pp. 1932-1938

Author(s):

Vinod Kumar Gurjar

Keyword(s):

Carboxylic Acid ◽

Virtual Screening ◽

Heterocyclic Compound ◽

Mechanism Of Action ◽

In Silico ◽

Heterocyclic Compounds ◽

Analytical Techniques ◽

Drug Resistant ◽

Alternate Mechanism ◽

Selection Of

Abstract: The extremely drug resistant may be a worldwide public ill health in recent years. Molecules with newer targets and an alternate mechanism of action is an urgent requirement of improvement of latest drugs. The utilization of heterocyclic compounds has been increased dramatically over the last 70 years due to their wide selection of technical applications and their favorable environmental and toxicological properties The 1,8-naphthyridine and quinoline 3-carboxylic acid derivatives that we'll manufacture during this method will change the potency and specificity of fluoroquinolones. Taking under consideration the findings, the goal is to style and manufacture 1, 8-naphthyridine and quinoline 3-carboxylic acid derivatives. The synthesized compounds are going to be characterized using multiple analytical techniques, virtual screening, and in-silico ADME/T prediction. Keywords: 1, 8-Naphthyridine, Quinoline, ADMET, Heterocyclic Compound

Download Full-text

The TransAlta High-Energy Piping Program—A Five-Year History

Journal of Pressure Vessel Technology ◽

10.1115/1.1344236 ◽

2000 ◽

Vol 123 (1) ◽

pp. 65-69 ◽

Cited By ~ 1

Author(s):

Marvin J. Cohn,

Keyword(s):

Creep Damage ◽

Analytical Techniques ◽

High Energy ◽

Management Plan ◽

Piping System ◽

Engineering Consulting ◽

Piping Systems ◽

Creep Fatigue ◽

Sustained Loads ◽

Selection Of

In 1995, the High-Energy Piping Strategic Management Plan (HEPSMP) was initiated at TransAlta Utilities Corporation (TAU) for the three generating facilities. At that time, it was recognized that several of the piping systems were exhibiting signs of creep relaxation, with some hangers bottomed or topped out online and/or offline. Previous hanger adjustment attempts were not always adequate. The program workscope included: 1) hot and cold piping system walkdowns, 2) selection of high-priority girth weld inspection locations, 3) examination of critical weldments, 4) weld repairs where necessary, 5) adjustments or modifications of malfunctioning steam line hangers, and 6) recommended work for future scheduled outages. Prior to 1996, examination locations were limited to the traditional locations of the terminal points at the boiler and turbine, with reexaminations occurring at arbitrary intervals. Since the terminal points are not necessarily the most highly stressed welds causing service-related creep damage, service damage may not occur first at the pre-1996 examined locations. There was a need to maximize the safety and integrity of these lines by ensuring that the highest risk welds were identified and given the highest priority for examination. An engineering consulting company was selected to prioritize the highest risk weldments for each piping system. This risk-based methodology included the prediction and evaluation of actual sustained loads, thermal expansion loads, operating loads, multiaxial stresses, creep relaxation, and cumulative creep life exhaustion. The technical process included detailed piping system walkdowns and application of advanced analytical techniques to predict and rank creep/fatigue damage for each piping system. TAU has concluded that the program has met its objective of successfully prioritizing inspection locations. The approach has also resulted in reducing the scope and cost of reexaminations. Phases 1 and 2 evaluations and examinations have been completed for all units. Results of some of the important aspects of this program are provided as case history studies.

Download Full-text

Exercising responsible leadership in a Singapore context

Leadership & Organization Development Journal ◽

10.1108/lodj-09-2015-0215 ◽

2018 ◽

Vol 39 (1) ◽

pp. 34-50 ◽

Cited By ~ 1

Author(s):

Carolyn Koh ◽

Mario Fernando ◽

Trevor Spedding

Keyword(s):

National Culture ◽

Effective Leadership ◽

Analytical Techniques ◽

Business Leaders ◽

Responsible Leadership ◽

Content Type ◽

Face To Face ◽

Practical Implications ◽

Purposive Selection ◽

Selection Of

Purpose The purpose of this paper is to explore the western developed notion of responsible leadership (RL) from a Singapore context. Design/methodology/approach Following the qualitative research tradition, face-to-face interviews with 20 influential Singaporean leaders were developed into case studies. Grounded theory methodology was applied to identify similarities and differences within and across cases. Findings The findings reveal that the interviewed Singaporean leaders projected traits and values consistent with western definitions of responsible and effective leadership. Findings also suggest that contextual factors such as national culture and the ethos of the nation as well as leaders’ relational intelligence influence RL. These factors also help responsible leaders to better manage the tension between responsible and effective leadership. Research limitations/implications The small and geographically bound sample size makes it difficult to generalise the findings of this study. As in other ethics studies, interviewees’ desire to present a socially desirable image of themselves could be high in this study. Finally, the methods and analytical techniques applied may be biased and be influenced by the purposive selection of the participants. Practical implications Singaporean business leaders may need to consider the importance of retaining and developing the national culture and ethos of the nation, since these are the factors that have been identified in this study as key to influencing RL. Originality/value This study identifies the factors that influence RL from a Singapore context. It extends the understanding of the mostly western-based multi-level theory of RL.

Download Full-text

Mobile Raman spectroscopy in astrobiology research

Philosophical Transactions of The Royal Society A Mathematical Physical and Engineering Sciences ◽

10.1098/rsta.2014.0202 ◽

2014 ◽

Vol 372 (2030) ◽

pp. 20140202 ◽

Cited By ~ 3

Author(s):

Peter Vandenabeele ◽

Jan Jehlička

Keyword(s):

Raman Spectroscopy ◽

Data Processing ◽

Analytical Techniques ◽

Research Areas ◽

Different Types ◽

Target Molecules ◽

Processing Techniques ◽

Spectroscopy Research ◽

Selection Of

Raman spectroscopy has proved to be a very useful technique in astrobiology research. Especially, working with mobile instrumentation during fieldwork can provide useful experiences in this field. In this work, we provide an overview of some important aspects of this research and, apart from defining different types of mobile Raman spectrometers, we highlight different reasons for this research. These include gathering experience and testing of mobile instruments, the selection of target molecules and to develop optimal data processing techniques for the identification of the spectra. We also identify the analytical techniques that it would be most appropriate to combine with Raman spectroscopy to maximize the obtained information and the synergy that exists with Raman spectroscopy research in other research areas, such as archaeometry and forensics.

Download Full-text

Perspectives on the Capabilities for the Selection of Strategic Projects

Sustainability ◽

10.3390/su12198191 ◽

2020 ◽

Vol 12 (19) ◽

pp. 8191

Author(s):

Khalifa Mohammed Al-Sobai ◽

Shaligram Pokharel ◽

Galal M. Abdella

Keyword(s):

Large Scale ◽

Quantitative Methods ◽

Project Selection ◽

Economic Benefits ◽

Research Directions ◽

Qualitative And Quantitative Methods ◽

Strategic Project ◽

Managerial Capabilities ◽

Selection Of

Strategic projects are large scale, complex, and require significant investments and resources. These projects aim at gaining long-term social and economic benefits. Therefore, organizations focusing on strategic projects should use a consistent approach that suits their strategy, capability, and long-term expectations. Based on the four research questions and content analysis of the literature, generic processes used for the strategic project selection in tandem with the managerial capabilities are identified in this paper. The generic processes and managerial capabilities are used to develop a generic framework for strategic project selection. The framework is used for literature analysis in the paper. The review shows that both qualitative and quantitative methods are used for strategic project selection. Some possible research directions have also been proposed at the end of the review. The paper provides value to both researchers and practitioners in terms of tools available and a guidance on project selection through a structured process framework.

Download Full-text

Determination of Polyphenols Using Liquid Chromatography–Tandem Mass Spectrometry Technique (LC–MS/MS): A Review

Antioxidants ◽

10.3390/antiox9060479 ◽

2020 ◽

Vol 9 (6) ◽

pp. 479 ◽

Cited By ~ 4

Author(s):

Olalla López-Fernández ◽

Rubén Domínguez ◽

Mirian Pateiro ◽

Paulo E.S. Munekata ◽

Gabriele Rocchetti ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Analytical Techniques ◽

Tandem Mass ◽

Beneficial Effects ◽

Mobile Phases ◽

Liquid Chromatography Tandem Mass ◽

Methodological Aspects ◽

Selection Of

In recent years, the consumption of polyphenols has been increasing, largely due to its beneficial effects on health. They are present in a wide variety of foods, but their extraction and characterization are complicated since they are mostly in complex matrices. For this reason, the use of selective, sensitive, and versatile analytical techniques such as liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) is necessary. In this review, the most relevant studies of the last years regarding the analysis of polyphenols in different matrices by comprehensive LC–MS/MS are discussed. Relevant steps such as extraction, sample purification, and chromatographic analysis methods are emphasized. In particular, the following methodological aspects are discussed: (a) the proper selection of the extraction technique, (b) the extraction and elution solvents, (c) the purification step, (d) the selection of both stationary and mobile phases for the chromatographic separation of compounds, and (e) the different conditions for mass spectrometry. Overall, this review presents the data from the most recent studies, in a comprehensive way, thus providing and simplifying the information of the great variety of works that exist in the literature on this wide topic.

Download Full-text