The relationship between mammary gland permeability and the factors related to mothers and their babies

2011 ◽  
Vol 26 (S2) ◽  
pp. 1108-1108
Author(s):  
B. Serim ◽  
A. Ozbek ◽  
M. Ormen ◽  
C. Ergin ◽  
A. Aydın ◽  
...  

IntroductionStudies have found that mothers normally have high sodium concentrations in their colostrum which shows a rapid decrease in the third day postpartum. A drop in breast milk sodium concentration is highly predictive for successful lactation.Objectives and aimsIn this study, the relationship between mammary gland permeability and the factors related to mothers and their babies were aimed to be investigated.MethodThe case group consisted of 150 consecutive healthy babies at postpartum 8–15 days. Edinburgh Postnatal Depression Scale, State and Trait Anxiety Inventory and Relationship Scale Questionnaire were applied to the mothers. Milk samples from all mothers were collected. Weights of babies at first month were recorded.ResultsIn babies with higher Na concentrations and Na/K ratio in their mothers’ milk, were found to gain less weight at the end of first month and also they were the first babies of the families included in the study. Mothers with higher concentrations of Na in their milk thought they were not appropriate to have a child, had poorer relationships with their own mothers, stated that they had no close friendships and had a past history of mental disorders at significance limits. The EPDS and STAI-I scores of mothers with elevated milk Na concentrations found to be higher.ConclusionRegarding this study's results, the risk factors causing an increase in the permeability of the mammary glands were determined as thoughts of not being suitable for motherhood, symptoms of postpartum depression and high levels of anxiety for the mothers.

2014 ◽  
pp. 140-152
Author(s):  
Manh Hoan Nguyen ◽  
Ngoc Thanh Cao

Background and Objective: HIV infection is also a cause of postpartum depression, however, in Vietnam, there has not yet the prevalence of postpartum depression in HIV infected women. The objective is to determine prevalence and related factors of postpartum depression in HIV infected women. Materials and Methods: From November 30th, 2012 to March 30th, 2014, a prospective cohort study is done at Dong Nai and Binh Duong province. The sample includes135 HIV infected women and 405 non infected women (ratio 1/3) who accepted to participate to the research. We used “Edinburgh Postnatal Depression Scale (EPDS) as a screening test when women hospitalized for delivery and 1 week, 6weeks postpartum. Mother who score EPDS ≥ 13 are likely to be suffering from depression. We exclude women who have EPDS ≥ 13 since just hospitalize. Data are collected by a structural questionaire. Results: At 6 weeks postpartum, prevalence of depression in HIV infected women is 61%, in the HIV non infected women is 8.7% (p < 0.001). There are statistical significant differences (p<0.05) between two groups for some factors: education, profession, income, past history of depression, child’s health, breast feeding. Logistical regression analysis determine these factors are related with depression: late diagnosis of HIV infection, child infected of HIV, feeling guilty of HIV infected and feeling guilty with their family. Multivariate regression analysis showed 4 factors are related with depression: HIV infection, living in the province, child’s health, past history of depression. Conclusion: Prevalence of postpartum depression in HIV infected women is 61.2%; risk of depression of postnatal HIV infected women is 6.4 times the risk of postnatal HIV non infected women, RR=6.4 (95% CI:4.3 – 9.4). Domestic women have lower risk than immigrant women from other province, RR=0.72 (95% CI:0.5 – 0.9). Past history of depression is a risk factor with RR=1.7 (95% CI:1.02 – 0.9. Women whose child is weak or die, RR=1.7(95% CI:0.9 – 3.1). Keywords: Postpartum depression, HIV-positive postpartum women


1998 ◽  
Vol 28 (1) ◽  
pp. 185-191 ◽  
Author(s):  
C. DUGGAN ◽  
P. SHAM ◽  
C. MINNE ◽  
A. LEE ◽  
R. MURRAY

Background. We examined a group of subjects at familial risk of depression and explored the relationship between the perceptions of parents and a history of depression. We also investigated: (a) whether any difference in perceived parenting found between those with and without a past history of depression was an artefact of the depression; and (b) whether the relationship between parenting and depression was explained by neuroticism.Method. We took a sample of first-degree relatives selected from a family study in depression and subdivided them by their history of mental illness on the SADS-L, into those: (a) without a history of mental illness (N=43); and (b) those who had fully recovered from an episode of RDC major depression (N=34). We compared the perceptions of parenting, as measured by the Parental Bonding Instrument (PBI), in these two groups having adjusted for the effect of neuroticism and subsyndromal depressive symptoms. We also had informants report on parenting of their siblings, the latter being subdivided into those with and without a past history of depression.Results. Relatives with a past history of depression showed lower care scores for both mother and father combined compared with the never ill relatives. The presence of a history of depression was associated with a non-significant reduction in the self-report care scores compared to the siblings report. Vulnerable personality (as measured by high neuroticism) and low perceived care were both found to exert independent effects in discriminating between the scores of relatives with and without a history of depression and there was no interaction between them.Conclusion. This study confirmed that low perceived parental care was associated with a past history of depression, that it was not entirely an artefact of having been depressed, and suggested that this association was partially independent of neuroticism.


Author(s):  
Alimohammad Ranjbar ◽  
Elahe Kamali Ardakani ◽  
Rahele Zareshahi

Aims: In Iranian culture, due to some narratives from the prophet Mohammad about the use of frankincense during pregnancy for increasing IQ in children, some women consume frankincense during expectancy. This study's goal is to evaluate the relationship between frankincense used during pregnancy and the incidence of ADHD. Methods: In this study, the case group comprised children 4-17 years old referring to Shahid Chamran Pharmacy in Yazd from summer to winter 2018 for receiving Methylphenidate, those with whom a psychologist had identified ADHD based on DSM-V factors.  The control group included children of the same age group but without ADHD. For data gathering, a checklist was used with some questions on smoking, family history of ADHD, presence/absence of a specific disease during pregnancy, frankincense used during pregnancy, and a chemical medication consumed during pregnancy. Results: The main result demonstrated that the children whose mothers used frankincense during pregnancy were 0.67 times less likely to be affected by ADHD than those whose mothers did not use this substance. However, the difference failed to be statistically significant (P>0.05). Conclusion: Some studies report that frankincense can bear a positive effect on the development of the brain and possibly adequate formation of dendrites trees, axons and induce proper communication between them, so the impact of frankincense on the brain may be justified by its protective effect against the hyperactive child.


2006 ◽  
Vol 40 (11-12) ◽  
pp. 1025-1030 ◽  
Author(s):  
Geoff Schrader ◽  
Frida Cheok ◽  
Ann-Louise Hordacre ◽  
Julie Marker

Objective: To determine characteristics which predict depression at 12 months after cardiac hospitalization, and track the natural history of depression. Method: Depressive symptoms were monitored at baseline, 3 and 12 months in a cohort of 785 patients, using the self-report Center for Epidemiological Studies Depression Scale. Multinomial regression analyses of baseline clinical and demographic variables identified characteristics associated with depression at 12 months. Results: Three baseline variables predicted moderate to severe depression at 12 months: depression during index admission, past history of emotional health problems and current smoking. For those who were depressed during cardiac hospitalization, 51% remained depressed at both 3 and 12 months. Persistence was more evident in patients who had moderate to severe depressive symptoms when hospitalized. Mild depression was as likely to persist as to remit. Conclusions: Three clinically accessible characteristics at the time of cardiac hospitalization can assist in predicting depression at 12 months and may aid treatment decisions. Depressive symptoms persist in a substantial proportion of cardiac patients up to 12 months after hospitalization.


2020 ◽  
Author(s):  
qahhar muhammad qadir ◽  
Alexander A. Kist

Using instantaneous aggregate arrival rate as an admission control parameter will contribute to either bandwidth under-utilization or over-utilization. Being bursty in nature and variable in rate, video flows might encode any rate between a range of minimum and maximum values. At the time the decision is made, if the measured rate is at the minimum value, the bandwidth might be over-utilized due to accepting more sessions than the link can accommodate. In contrast, it might be under-utilized if the measured rate is at the maximum value due to rejecting more sessions than the link can accommodate. The burstiness can be taken into account by considering the past history of the traffic. This paper investigates the suitability of the average aggregate arrival rate instead of the instantaneous aggregate arrival rate for video admission decisions. It establishes a mathematical model to predict the relationship between the two rates. Simulation results confirm that the average aggregate arrival rate is a more efficient decision factor for a small number of flows. Although it has no additional advantage for moderate and large number of flows, it still can stabilize the admission decision by smoothing the burstiness of a set of the instantaneous rates (within the measurement period) over a period of time.


2020 ◽  
Author(s):  
Alexandra Lautarescu ◽  
Suresh Victor ◽  
Alex Lau-Zhu ◽  
Serena J. Counsell ◽  
Anthony David Edwards ◽  
...  

Background: Timely and accurate detection of perinatal mental health problems is essential for the wellbeing of both mother and child. Growing evidence has suggested that the Edinburgh Postnatal Depression Scale (EPDS) is not a unidimensional measure of perinatal depression, but can be used to screen for anxiety disorders.Methods: We aimed to assess the factor structure of the EPDS in 3 different groups of women: n=266 pregnant women at high-risk of depression (“Perinatal Stress Study”), n=471 pregnant women from a community sample, and n=637 early postnatal women from a community sample (“developing Human Connectome Project”). Exploratory factor analysis (40% of each sample) and confirmatory factor analysis (60% of each sample) were performed. The relationship between EPDS scores and history of mental health was investigated. Results: Results suggested that a 3-factor model (depression, anxiety, and anhedonia) is the most appropriate across groups. The anxiety subscale (EPDS 3A) emerged consistently and was related to maternal history of anxiety disorders. Total EPDS score was related to history of mental health problems. Limitations: Although data were collected on maternal history of mental health, there was no standardized diagnostic interview administered to assess the relationship between EPDS 3A and a current diagnosis of anxiety disorder. Conclusions: A better understanding of the multi-factorial structure of the EPDS can inform diagnosis and management of women in the prenatal and postnatal period. The EPDS 3A could be used to provide initial screening information for anxiety in situations where a validated anxiety questionnaire is not administered.


2020 ◽  
Vol 51 (02) ◽  
pp. 154-159
Author(s):  
Atsuro Daida ◽  
Gaku Yamanaka ◽  
Shin-ichi Tsujimoto ◽  
Mina Yokoyama ◽  
Kuniyoshi Hayashi ◽  
...  

AbstractSome studies have shown that sedative antihistamines prolong febrile seizure duration. Although the collective evidence is still mixed, the Japanese Society of Child Neurology released guidelines in 2015 that contraindicated the use of sedative antihistamines in patients with febrile seizure. Focused on addressing limitations of previous studies, we conducted a cross-sectional study to evaluate the relationship between febrile seizure duration and the use of sedative antihistamines. Data were collected from patients who visited St. Luke's International Hospital due to febrile seizure between August 2013 and February 2016. Patients were divided into groups based on their prescribed medications: sedative antihistamine, nonsedative antihistamine, and no antihistamine. Seizure duration was the primary outcome and was examined using multivariate analyses. Of the 426 patients included, sedative antihistamines were administered to 24 patients. The median seizure duration was approximately 3 minutes in all three groups. There was no statistical difference in the bivariate (p = 0.422) or multivariate analyses (p = 0.544). Our results do not support the relationship between sedative antihistamine use and prolonged duration of febrile seizure. These results suggest that the use of antihistamines may be considered for patients with past history of febrile seizure, when appropriate.


1975 ◽  
Vol 62 (1) ◽  
pp. 157-174
Author(s):  
DA Wright

In fourth instar larvae of Camptochironomus tentans, net sodium uptake from 2 mM-NaCl has an electrogenic component. During net uptake the transepithelial potential (TEP) alters from a value of approximately - 40 mV (sign refers to haemolymph), in depleted animals, to approximately o mV. The TEP in depleted larvae is dependent upon external sodium concentration above about I mM-Na+, becoming increasingly electropositive (haemolymph relative to medium) at high sodium concentrations. This effect is exaggerated in Na2SO4 compared with NaCl. At an external concentration of 2mM-NaCl, chloride is carried by an electroneutral mechanism, probably a closely coupled Cl-/anion exchange. However, it is possible that chloride transport could become somewhat electrogenic at higher concentrations. Lithium competes with sodium for the electrogenic pump. Observed TEPs differ greatly from those required to maintain passively the haemolymph concentrations of sodium and chloride.


1987 ◽  
Vol 17 (1) ◽  
pp. 155-161 ◽  
Author(s):  
Randy Katz ◽  
Peter McGuffin

SynopsisThis study examined the relationship between personality factors and depression in subjects who may have a familial vulnerability to depression (i.e. first-degree relatives of depressed patients). Four groups comprised our study sample: relatives who had never experienced a psychiatric episode of depression; relatives who had experienced a psychiatric episode of depression but were currently well; relatives who had never experienced a psychiatric episode of depression but were currently depressed; and relatives who had experienced a past history of depression and were currently depressed. Of the four personality characteristics measured (Psychoticism, Extraversion, Neuroticism and Lie), the only significant effects between groups appeared to be attributable to Neuroticism (N).The strongest association was between current illness and N. There was also a tendency for subjects with a past history of depression to have an inflated N score. However, this appeared to be associated with the presence of current depressive symptomatology. Our findings indicate that when current symptomatology is taken into account Neuroticism does not seem to reflect the trait of liability to depression, but is strongly associated with the state of being depressed.


1983 ◽  
Vol 143 (2) ◽  
pp. 133-138 ◽  
Author(s):  
K. O'Sullivan ◽  
P. Whillans ◽  
M. Daly ◽  
B. Carroll ◽  
A. Clare ◽  
...  

SummaryThree hundred male Irish alcoholics were selected from 508 consecutive alcoholic admissions to hospital. Using well defined diagnostic criteria, they were divided into three subgroups (1) primary alcoholics, (2) alcoholics with secondary affective disorder and (3) those with primary affective disorder and secondary alcoholism. Although the three groups reported differences in past history and family history of affective disorder and in time spent in hospital for both alcoholism and affective disorder, there was little to distinguish them in behaviour associated with alcoholism or in family history of alcoholism. The implications of these findings and their significance for the relationship of affective disorder and alcoholism are discussed.


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