P-611 - Differences in emotional states of anxiety, depression and stress between patients with diabetes mellitus and psychiatric outpatients to the general population in Greece

2012 ◽  
Vol 27 ◽  
pp. 1
Author(s):  
G. Lyrakos ◽  
E. Hatziagelaki ◽  
I. Spyropoulos ◽  
A. Goundella ◽  
M. Karachalios ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
General Population ◽  
Emotional States ◽  
Psychiatric Outpatients ◽  
Patients With Diabetes ◽  
Anxiety Depression

scholarly journals Depression, anxiety, and associated factors in patients with diabetes: evidence from the Anxiety, Depression, and Personality Traits in Diabetes Mellitus (ADAPT-DM) study

2020 ◽  
Author(s):  
Mohammad Farris Iman Leong Bin Abdullah ◽  
Sy-Cherng Luke Woon ◽  
Hatta Sidi ◽  
Arun Ravindran ◽  
Paula Junggar Gosse ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Personality Traits ◽  
Associated Factors ◽  
Diabetic Patients ◽  
Depression And Anxiety ◽  
Prevalence Of Depression ◽  
Patients With Diabetes ◽  
Health Related Qol ◽  
Health Related ◽  
Anxiety Depression

Abstract Background Depression and anxiety are common psychiatric complications affecting patients with diabetes mellitus. However, data on the prevalence of depression, anxiety, and associated factors among Malaysian diabetic patients is scarce. The Anxiety, Depression, and Personality Traits in Diabetes Mellitus (ADAPT-DM) study aimed to determine the prevalence of depression and anxiety, and their associated factors in the Malaysian diabetic population. Methods This cross-sectional study recruited 300 diabetic patients via convenience sampling from the Endocrine outpatient clinic of Universiti Kebangsaan Malaysia Medical Centre, a tertiary referral healthcare facility in Kuala Lumpur. Socio-demographic characteristics and clinical history were obtained from each participant. The Generalised Anxiety Disorder-7 (GAD-7) was administered to assess anxiety symptoms, the Beck Depression Inventory (BDI) to assess depressive symptoms, the Big Five Inventory (BFI) to evaluate personality traits, and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) to measure quality of life (QOL). Multivariate logistic regression analyses were performed to determine the association between various factors, and depression and anxiety. Results The prevalence of depression was 20% (n = 60) while anxiety was 9% (n = 27). Co-morbid depression (adjusted OR = 24.91, 95% CI = 5.67–109.42, p < 0.001), neuroticism (adjusted OR = 9.24, 95% CI = 2.03–42.03, p = 0.004), and greater physical health-related QOL (adjusted OR = 1.67, 95% CI = 1.07–2.59, p = 0.024) increased the odds of developing anxiety, while psychological QOL (adjusted OR = 0.41, 95% CI = 0.21–0.79, p = 0.008) was protective. Co-morbid anxiety (adjusted OR = 20.06, 95% CI = 4.70–85.57, p < 0.001) increased the odds of depression, while older age (adjusted OR = 0.96, 95% CI = 0.92–0.99, p = 0.012), regular religious practice (adjusted OR= 0.08, 95% CI= 0.01-0.56, p= 0.011) and physical health-related QOL (adjusted OR = 0.72, 95% CI = 0.59–0.89, p = 0.002) were protective. Conclusions The study findings signify the need to screen for co-morbid depression and anxiety, as well as personality traits and QOL, and to include psychosocial interventions when planning a multidisciplinary approach to managing diabetes.

scholarly journals Depression, anxiety, and associated factors in patients with diabetes: evidence from the anxiety, depression, and personality traits in diabetes mellitus (ADAPT-DM) study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Luke Sy-Cherng Woon ◽  
Hatta Bin Sidi ◽  
Arun Ravindran ◽  
Paula Junggar Gosse ◽  
Roslyn Laurie Mainland ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Personality Traits ◽  
Associated Factors ◽  
Patients With Diabetes ◽  
Anxiety Depression

scholarly journals Risk of colorectal cancer in patients with diabetes mellitus: A Swedish nationwide cohort study

PLoS Medicine ◽  
2020 ◽  
Vol 17 (11) ◽  
pp. e1003431
Author(s):  
Uzair Ali Khan ◽  
Mahdi Fallah ◽  
Kristina Sundquist ◽  
Jan Sundquist ◽  
Hermann Brenner ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Colorectal Cancer ◽  
Cohort Study ◽  
Family History ◽  
General Population ◽  
Early Onset ◽  
Swedish Population ◽  
Crc Screening ◽  
Patients With Diabetes ◽  
History Of

Background Colorectal cancer (CRC) incidence is increasing among young adults below screening age, despite the effectiveness of screening in older populations. Individuals with diabetes mellitus are at increased risk of early-onset CRC. We aimed to determine how many years earlier than the general population patients with diabetes with/without family history of CRC reach the threshold risk at which CRC screening is recommended to the general population. Methods and findings A nationwide cohort study (follow-up:1964–2015) involving all Swedish residents born after 1931 and their parents was carried out using record linkage of Swedish Population Register, Cancer Registry, National Patient Register, and Multi-Generation Register. Of 12,614,256 individuals who were followed between 1964 and 2015 (51% men; age range at baseline 0–107 years), 162,226 developed CRC, and 559,375 developed diabetes. Age-specific 10-year cumulative risk curves were used to draw conclusions about how many years earlier patients with diabetes reach the 10-year cumulative risks of CRC in 50-year-old men and women (most common age of first screening), which were 0.44% and 0.41%, respectively. Diabetic patients attained the screening level of CRC risk earlier than the general Swedish population. Men with diabetes reached 0.44% risk at age 45 (5 years earlier than the recommended age of screening). In women with diabetes, the risk advancement was 4 years. Risk was more pronounced for those with additional family history of CRC (12–21 years earlier depending on sex and benchmark starting age of screening). The study limitations include lack of detailed information on diabetes type, lifestyle factors, and colonoscopy data. Conclusions Using high-quality registers, this study is, to our knowledge, the first one that provides novel evidence-based information for risk-adapted starting ages of CRC screening for patients with diabetes, who are at higher risk of early-onset CRC than the general population.

scholarly journals Effect of Continuous Nursing on Quality of Life of Patients with Diabetes Mellitus

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Honglei Lv ◽  
Junling Li
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Anxiety And Depression ◽  
Nursing Satisfaction ◽  
Patients With Diabetes ◽  
Group A ◽  
Group B ◽  
Anxiety Depression ◽  
Better Than

Objective: To analyze the effect of continuous nursing on the quality of life of patients with diabetes. Methods: From August 2019 to August 2020, 76 patients with diabetes were selected and randomly divided into group A and group B. group a received continuous nursing and group B received routine nursing. Results: The compliance of health education in group A was better than that in group B (P < 0.05);The score of quality of life in group A was better than that in group B (P < 0.05);The scores of anxiety and depression in group A were better than those in group B (P < 0.05);The nursing satisfaction of group A was 97.37%, which was better than that of group B 76.32%, P < 0.05.Conclusions: Continuous nursing for patients with diabetes can improve the quality of life, relieve anxiety, depression and other negative emotions, and improve nursing satisfaction.

P4433Equal cardiovascular risk in patients with diabetes mellitus versus rheumatoid arthritis?

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
B B Loegstrup ◽  
T Ellingsen ◽  
A B Pedersen ◽  
B Darvalics ◽  
H E Botker ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Diabetes Mellitus ◽  
Cardiovascular Disease ◽  
Relative Risk ◽  
General Population ◽  
Coronary Revascularization ◽  
Control Group ◽  
Individual Record ◽  
Patients With Diabetes

Abstract Purpose To examine whether the risk of cardiovascular disease (heart failure (HF), ischemic heart disease (IHD), myocardial infarction (MI), and coronary revascularization) in patients with rheumatoid arthritis (RA) is comparable to the risk in patients with diabetes mellitus (DM) and general population. Methods The study included the entire Danish population encompassing about 5.7 million inhabitants. Through individual record linkage of nationwide administrative health registries, the authors identified subjects who developed RA and DM and compared these to a matched general population. The cohorts were followed from 1 January 1995 until December 2016. Results The study population consisted of a cohort of 15,491 RA patients, 309,698 DM patients, and a general population cohort of 77,455 subjects matched by age, sex, and year of diagnosis with the RA cohort. Cumulative incidence for HF, IHD, MI, PCI (percutaneous coronary intervention) and CABG (coronary artery bypass grafting) are shown in figure 1. The adjusted hazard ratio (HR) for diagnosis of HF within the 10-year observational period for RA (1.46; 95% CI 1.34–1.59) and DM (1.86; 95% CI 1.78–1.95) were increased compared to the general population. Comparing the risk of HF within the follow-up period a 21% relative risk (HR 0.79, 95% CI 0.73–0.85) reduction of HF in RA compared to DM patients was observed. The HR for IHD development during the follow-up period for RA (1.36; 95% CI 1.25–1.48) and DM (1.64; 95% CI 1.58–1.72) were increased compared to control group. Comparing the risk of IHD within the follow-up period a 17% relative risk (HR 0.83, 95% CI 0.77–0.89) reduction for IHD development in RA compared to DM patients. The HR for MI was increased both in RA (1.48; 95% CI 1.34–1.63) and DM (1.57; 95% CI 1.49–1.65) compared to the control group, without any statistical difference within RA and DM. According to the coronary revascularization, comparable increased numbers of PCI were observed in RA (1.37; 95% CI 1.22–1.54) and DM (1.50; 95% CI 1.41–1.59) patients compared to control subjects. Interestingly, the HR of coronary by-pass grafting (CABG) for RA (1.20; 95% CI 0.98–1.49) and DM (1.99; 95% CI 1.80–2.19) resulting in an adjusted 39% relative risk (0.61 95% CI 0.50–0.74) reduction for CABG in RA compared to DM patients. Figure 1 Conclusions Patients with RA are at increased risk of cardiovascular disease when compared to the general population although slightly lower than observed among patients with DM. Revascularization with CABG was only increased among DM patients, which likely reflects physician compliance to guidelines recommending CABG in case of multivessel disease among DM patients. Patients with RA should be considered for prophylactic strategies in the same way as recommended for patients with DM.

scholarly journals A Cohort Study of Antihyperglycemic Medication Exposure and Gastric Cancer Risk

2020 ◽  
Vol 9 (2) ◽  
pp. 435 ◽  
Author(s):  
Audrius Dulskas ◽  
Ausvydas Patasius ◽  
Auguste Kaceniene ◽  
Donata Linkeviciute-Ulinskiene ◽  
Lina Zabuliene ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gastric Cancer ◽  
Type 2 Diabetes ◽  
General Population ◽  
Cancer Risk ◽  
Lower Risk ◽  
Gastric Cancer Risk ◽  
Expected Number ◽  
Patients With Diabetes

We assessed gastric cancer risk in type 2 diabetes mellitus patients. Gastric cancer patients with diabetes between 2001–2012 were identified. Four groups were analysed: combination therapy with metformin users; insulin and other medication users; metformin and insulin users; and sulfonylurea users. Standardised incidence ratios (SIRs) for gastric cancers as a ratio of the observed number of cancer cases in people with diabetes to the expected number of cancer cases in the underlying general population were calculated. A total of 99,992 patients with diabetes were analysed and 337 gastric cancer cases in patients with diabetes were observed when compared to the expected number of 400.54 gastric cancer cases, according to the cancer rates of the general population (SIR 0.84, 95% confidence interval (CI): 0.76–0.94). Lower risk of gastric cancer was found both in male and female patients with diabetes, however, risk among females was insignificantly lower. Higher gastric cancer risk was found in the group of diabetic patients treated with sulfonylureas (SIR 1.31, 95% CI: 1.04–1.65) and significantly lower risk than expected from the general population was found in the group of metformin users (SIR 0.75, 95% CI: 0.66–0.86). Type 2 diabetes mellitus was not associated with increased risk of gastric cancer. Metformin might decrease the risk of gastric cancer in patients with diabetes, while sulfonylureas may increase gastric cancer risk.

scholarly journals Depression, anxiety, and associated factors in patients with diabetes: evidence from the Anxiety, Depression, and Personality Traits in Diabetes Mellitus (ADAPT-DM) study

2020 ◽  
Author(s):  
Sy-Cherng Luke Woon ◽  
Hatta Sidi ◽  
Arun Ravindran ◽  
Paula Junggar Gosse ◽  
Roslyn Laurie Mainland ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Personality Traits ◽  
Associated Factors ◽  
Diabetic Patients ◽  
Depression And Anxiety ◽  
Prevalence Of Depression ◽  
Patients With Diabetes ◽  
Anxiety Depression

Abstract Background: Depression and anxiety are common psychiatric complications affecting patients with diabetes mellitus. However, data on the prevalence of depression, anxiety, and associated factors among Malaysian diabetic patients is scarce. The Anxiety, Depression, and Personality Traits in Diabetes Mellitus (ADAPT-DM) study aimed to determine the prevalence of depression and anxiety, and their associated factors in the Malaysian diabetic population. Methods: This cross-sectional study recruited 300 diabetic patients via convenience sampling from the Endocrine outpatient clinic of Universiti Kebangsaan Malaysia Medical Centre, a tertiary referral healthcare facility in Kuala Lumpur. Socio-demographic characteristics and clinical history were obtained from each participant. The Generalised Anxiety Disorder-7 (GAD-7) was administered to assess anxiety symptoms, the Beck Depression Inventory (BDI) to assess depressive symptoms, the Big Five Inventory (BFI) to evaluate personality traits, and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) to measure quality of life (QOL). Stepwise multiple logistic regression analyses were performed to determine the association between various factors, and depression and anxiety. Results: The prevalence of depression was 20% (n = 60) while anxiety was 9% (n = 27). Co-morbid depression (adjusted odds ratio [OR] = 9.89, 95% confidence interval [CI] = 2.63- 37.14, p = 0.001) and neuroticism (adjusted OR = 11.66, 95% CI= 2.69-50.47, p = 0.001) increased the odds of developing anxiety, while conscientiousness (adjusted OR = 0.45, 95% CI= 0.23-0.80, p = 0.004) and greater psychological-related QOL (adjusted OR = 0.47, 95% CI= 0.29-0.75, p = 0.002) were protective. Co-morbid anxiety (adjusted OR = 19.83, 95% CI = 5.63- 69.92, p < 0.001) increased the odds of depression, while older age (adjusted OR = 0.96, 95% CI = 0.93–0.98, p = 0.002), social relationship-related QOL (adjusted OR= 0.84, 95% CI = 0.71- .0.99, p= 0.047), and physical health-related QOL (adjusted OR = 0.69, 95% CI = 0.58-0.83, p < 0.001) were protective. Conclusions: The study findings signify the need to screen for co-morbid depression and anxiety, as well as personality traits and QOL, and to include psychosocial interventions when planning a multidisciplinary approach to managing diabetes.

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