Maternal and paternal history of myocardial infarction and risk of cardiovascular disease in men and women

Background: In the 2018 AHA/ACC Cholesterol guideline, risk stratification is an essential element. The use of a Pooled Cohort Equation (PCE) is recommended for individuals without atherosclerotic cardiovascular disease (ASCVD), and the new dichotomous classification of very high-risk vs. high-risk has been introduced for patients with ASCVD. These distinct risk stratification systems mainly rely on traditional risk factors, raising the possibility that a single model can predict major adverse cardiovascular events (MACEs) in persons with and without ASCVD. Methods: We studied 11,335 ARIC participants with (n=885) and without (n=10,450) a history of ASCVD (myocardial infarction, ischemic stroke, and symptomatic peripheral artery disease) at baseline (1996-98). We modeled factors in the PCE and the new classification for ASCVD patients (Figure legend) in a single CVD prediction model. We examined their associations with MACEs (myocardial infarction, stroke, and heart failure) using Cox models and evaluated the discrimination and calibration for a single model including those factors. Results: During a median follow-up of 18.4 years, there were 3,658 MACEs (3,105 in participants without ASCVD). In general, the factors in the PCE and the risk classification system for ASCVD patients were associated similarly with MACEs regardless of baseline ASCVD status, although age and systolic blood pressure showed significant interactions. A single model with these predictors and the relevant interaction terms showed good calibration and discrimination for those with and without ASCVD (c-statistic=0.729 and 0.704, respectively) (Figure). Conclusion: A single CVD prediction model performed well in persons with and without ASCVD. This approach will provide a specific predicted risk to ASCVD patients (instead of dichotomy of very high vs. high risk) and eliminate a practice gap between primary vs. secondary prevention due to different risk prediction tools.

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Parental History of Hypertension and Myocardial Infarction Predicts Cardiovascular Responses to Behavioral Stressors in Middle-aged Men and Women

Psychophysiology ◽

10.1111/j.1469-8986.1988.tb01241.x ◽

1988 ◽

Vol 25 (3) ◽

pp. 269-277 ◽

Cited By ~ 22

Author(s):

Catherine M. Stoney ◽

Karen A. Matthews

Keyword(s):

Myocardial Infarction ◽

Cardiovascular Responses ◽

Middle Aged ◽

Parental History ◽

Men And Women ◽

History Of

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Peanut Consumption and Risk of Stroke and Ischemic Heart Disease in Japanese Men and Women: The JPHC Study

Stroke ◽

10.1161/strokeaha.120.031212 ◽

2021 ◽

Author(s):

Satoyo Ikehara ◽

Hiroyasu Iso ◽

Yoshihiro Kokubo ◽

Kazumasa Yamagishi ◽

Isao Saito ◽

...

Keyword(s):

Public Health ◽

Cardiovascular Disease ◽

Heart Disease ◽

Ischemic Stroke ◽

Ischemic Heart Disease ◽

Ischemic Heart ◽

Japanese Men ◽

Food Frequency ◽

Men And Women ◽

History Of

Background and Purpose: Several prospective cohort studies and a randomized clinical trial have shown the beneficial effects of peanut consumption on cardiovascular disease and its risk factors. We examined the association between peanut consumption and risk of cardiovascular disease in Japanese men and women. Methods: We analyzed data of 74 793 participants aged 45 to 74 years who completed a lifestyle questionnaire including the validated food frequency questionnaire in the Japan Public Health Center–based Prospective Study. They were followed up from 1995 to 2009 for cohort I and from 1998 to 1999 to 2012 for cohort II. Peanut consumption was calculated from the food frequency questionnaire, and the end points were incidence of stroke, ischemic heart disease, and cardiovascular disease (stroke and ischemic heart disease). Results: During a median follow-up of 14.8 years, 3,599 strokes and 849 ischemic heart diseases were reported. Higher peanut consumption was associated with reduced risks of total stroke, ischemic stroke, and cardiovascular disease among men and women. The multivariable hazard ratios (95% CIs) for the highest versus lowest quartiles of peanut consumption after adjustment for age, sex, public health center, smoking, alcohol consumption, perceived stress level, physical activity, vegetable, fruit, fish, soy, sodium and total energy intakes, body mass index, history of hypertension, history of diabetes, and cholesterol-lowering drug were 0.84 (0.77–0.93, P for trend=0.002) for total stroke, 0.80 (0.71–0.90, P for trend=0.002) for ischemic stroke, 0.93 (0.79–1.08, P for trend=0.27) for hemorrhagic stroke, 0.97 (0.80–1.17, P for trend=0.81) for ischemic heart disease and 0.87 (0.80–0.94, P for trend=0.004) for cardiovascular disease, and these associations were similarly observed in both sexes. Conclusions: Higher peanut consumption was associated with reduced risk of stroke, especially ischemic stroke, but not ischemic heart disease in Japanese men and women.

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Abstract WP226: The Association of Green Tea and Coffee Consumption With Mortality From Cardiovascular Disease and All Causes Among Persons With and Without History of Stroke or Myocardial Infarction: The JACC Study

Stroke ◽

10.1161/str.51.suppl_1.wp226 ◽

2020 ◽

Vol 51 (Suppl_1) ◽

Author(s):

Masayuki Teramoto ◽

Isao Muraki ◽

Kokoro Shirai ◽

Akiko Tamakoshi ◽

Hiroyasu Iso

Keyword(s):

Myocardial Infarction ◽

Cardiovascular Disease ◽

General Population ◽

Green Tea ◽

Coffee Consumption ◽

Tea Consumption ◽

Food Frequency ◽

All Cause Mortality ◽

History Of

Background: Both green tea and coffee consumption have been associated with lower risks of mortality from cardiovascular disease (CVD) and all causes in general population, but little is known about those impact on persons with history of CVD. We examined the association of those consumption with these mortalities among persons with and without history of stroke or myocardial infarction in general population. Methods: The study subjects were 60,664 participants (896 stroke and 1751 myocardial infarction survivors and 58,017 persons with no history of stroke or myocardial infarction), aged 40-79 years at the baseline (1988-1990), who completed a lifestyle and medical history questionnaire including self-administered food frequency under the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study). Results: During the median follow-up of 18.5 years, a total of 12,745 (7,458 men and 5,287 women) deaths including 3,737 CVD deaths were documented. Green tea and coffee consumption were inversely associated with CVD and all-cause mortality among myocardial infarction survivors as well as persons without history of stroke or myocardial infarction. After adjustment for known cardiovascular risk factors, the lower risks of mortality from CVD and all-causes associated with frequent green tea consumption (5-6 and ≥7 cups/day) or coffee consumption (≥2 cups/day) remained statistical. Conclusions: Both green tea and coffee consumption were inversely associated with risks of CVD and all-cause mortality among myocardial infarction survivors and persons without history of stroke or myocardial infarction.

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A history of smoking does not reduce long-term benefits of cardiac rehabilitation on cardiorespiratory fitness in men and women with cardiovascular disease

Applied Physiology Nutrition and Metabolism ◽

10.1139/apnm-2020-0349 ◽

2020 ◽

Author(s):

Kenneth Shinkichi Noguchi ◽

Michael Pryzbek ◽

Kevin Moncion ◽

Angelica McQuarrie ◽

Maureen J. MacDonald ◽

...

Keyword(s):

Cardiovascular Disease ◽

Cardiac Rehabilitation ◽

Cardiorespiratory Fitness ◽

Smoking Behaviour ◽

Smoking History ◽

Cardiac Events ◽

Men And Women ◽

All Cause Mortality ◽

History Of

Smoking is an important risk factor for cardiovascular disease and all-cause mortality. Cardiac rehabilitation (CR) is effective for reducing the risk of recurrent cardiac events through improving cardiorespiratory fitness (CRF). Little is known about the influence of smoking on CRF throughout long-term CR. The purpose of this analysis was to compare CRF trajectories among individuals with positive and negative smoking history enrolled in long-term CR. Participants had a positive smoking history if they currently smoke or formerly smoked (Smoke+, n=55, mean age=64.9 ± 9.0 years) and had a negative history if they never smoked (Smoke–, n=34, mean age=61.4 ± 9.0 years). CRF (VO2peak) was measured at baseline and annually thereafter for 6 years. The Smoke+ group had lower CRF compared to the Smoke– group over enrollment (β=-3.29 (SE=1.40), 95% CI -6.04, -0.54, p=0.02), but there was no interaction of smoking history and enrollment (β=0.35 (SE=0.21), 95% CI -0.06, 0.77, p=0.10). Moreover, trajectories were not influenced by pack-years (β=0.01 (SE=0.01), 95% CI -0.01, 0.04, p=0.23) or time smoke-free (β=-0.002 (SE=0.01), 95% CI -0.02, 0.02, p=0.80). Although the trajectories of CRF do not appear to be affected by smoking behaviour, individuals without a history of smoking maintained higher CRF throughout enrollment. Novelty bullets: • The benefits of long-term exercise-based cardiac rehabilitation on cardiorespiratory fitness are similar between those who have smoked and those who have never smoked. • Neither the number of pack-years nor the length of time spent smoke-free influence cardiorespiratory fitness trajectories following long-term cardiac rehabilitation.

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Effects of Caffeine and Stress on Biomarkers of Cardiovascular Disease in Healthy Men and Women with a Family History of Hypertension

Stress and Health ◽

10.1002/smi.2486 ◽

2013 ◽

Vol 29 (5) ◽

pp. 401-409 ◽

Cited By ~ 11

Author(s):

Jeanette M. Bennett ◽

Isabella M. Rodrigues ◽

Laura Cousino Klein

Keyword(s):

Cardiovascular Disease ◽

Family History ◽

Men And Women ◽

Healthy Men ◽

History Of ◽

Family History Of Hypertension

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Impact of history of diabetes mellitus on hospital mortality in men and women with first acute myocardial infarction

The American Journal of Cardiology ◽

10.1016/s0002-9149(00)00800-6 ◽

2000 ◽

Vol 85 (12) ◽

pp. 1486-1489 ◽

Cited By ~ 38

Author(s):

Viola Vaccarino ◽

Lori Parsons ◽

Nathan R. Every ◽

Hal V. Barron ◽

Harlan M. Krumholz

Keyword(s):

Diabetes Mellitus ◽

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Hospital Mortality ◽

Men And Women ◽

History Of

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Prevalence of Cardiovascular Risk Factors Among Patients with Acute Myocardial Infarction and New Left Bundle Branch Block in North East Romania

Revista de Chimie ◽

10.37358/rc.18.6.6367 ◽

2018 ◽

Vol 69 (6) ◽

pp. 1554-1557

Author(s):

Larisa Anghel ◽

Catalina Arsenescu Georgescu

Keyword(s):

Risk Factors ◽

Myocardial Infarction ◽

Cardiovascular Disease ◽

Acute Myocardial Infarction ◽

Cardiovascular Risk ◽

Left Bundle Branch Block ◽

New Left ◽

Bundle Branch Block ◽

North East ◽

History Of

The prevalence of coronary artery disease, a major contributor to cardiovascular disease, is related to the increasing prevalence of modifiable risk factors.The aim of our study was to determine the risk factors for acute myocardial infarction among patients from North East Romania.We evaluated patients with acute myocardial infarction with or without left bundle-branch block, hospitalized in Georgescu Institute of Cardiovascular Disease Iasi for three years. The results of our study show that patients with acute myocardial infarction and new left bundle branch block have a more recent history of hypertension, dyslipidemia and smoker status compared to patients without left bundle branch block. Nearly two thirds of patients included in the study (65.47%) had an elevated cholesterol level, with a high prevalence of dyslipidemia in patients with myocardial infarction and new left bundle branch block. More than two-thirds of patients with new left bundle branch block had a history of arterial hypertension (69.04% vs. 50.0%, p = 0.354), especially grade 2 hypertension, with a slight predominance in those with new left bundle branch block, but without statistically significant differences between the two groups (45.23% vs. 30.95%, p = 0.358). Early identification of modifiable risk factors is vital to set the strategy for prevention and special attention must be paid to smoking. An adequate control of cardiovascular risk factors would result in a significant reduction of coronary events in patients from the North East part of Romania.

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PRIMARY XANTHOMA TUBEROSUM IN CHILDREN

PEDIATRICS ◽

10.1542/peds.23.1.67 ◽

1959 ◽

Vol 23 (1) ◽

pp. 67-75

Author(s):

Jack E. McCleary ◽

Louis A. Brunsting ◽

Roger L. J. Kennedy

Keyword(s):

Myocardial Infarction ◽

Cardiovascular Disease ◽

Angina Pectoris ◽

Cardiac Disease ◽

Blood Lipids ◽

Close Relative ◽

History Of ◽

Coronary Blood Vessels ◽

The One

A brief classification of xanthomatoses is presented. In an attempt to remove some of the confusion contributed by the several different meanings for the term "hyperlipemia," the term "hyperneutralipemia" is introduced to indicate an elevation of the concentrations of neutral fat in the serum. The term "hyperlipemia" is retained to mean an elevation of values for any of the blood lipids. The term "primary xanthoma tuberosum" designates the classic idiopathic form of xanthoma tuberosum associated with hypercholesteremia and without hyperneutralipemia. The primary purpose of this paper is to review the outcome of 11 cases of primary xanthoma tuberosum in children seen at the Mayo Clinic. Five of the eleven are known to be dead from cardiovascular disease, and one other is presumed to be dead. In five of the six patients angina pectoris developed before death. Two patients who are still living have angina pectoris, one having suffered myocardial infarction. Necropsy of four patients showed atheromatous involvement of the coronary blood vessels to be a prominent finding. Three of the patients died before they reached the age of 15 years. Two of the patients were brother and sister. Of the remaining nine patients, four gave a family history of cardiac disease occurring in a close relative early in life and five patients had relatives with cutaneous xanthomas. In the one family studied, all five members had hypercholestenemia.

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