scholarly journals Making Modern Migraine Medieval: Men of Science, Hildegard of Bingen and the Life of a Retrospective Diagnosis

2014 ◽  
Vol 58 (3) ◽  
pp. 354-374 ◽  
Author(s):  
Katherine Foxhall

AbstractCharles Singer’s retrospective diagnosis of Hildegard of Bingen as a migraine sufferer, first made in 1913, has become commonly accepted. This article uses Hildegard as a case study to shift our focus from a polarised debate about the merits or otherwise of retrospective diagnosis, to examine instead what happens when diagnoses take on lives of their own. It argues that simply championing or rejecting retrospective diagnosis is not enough; that we need instead to appreciate how, at the moment of creation, a diagnosis reflects the significance of particular medical signs and theories in historical context and how, when and why such diagnoses can come to do meaningful work when subsequently mobilised as scientific ‘fact’. This article first traces the emergence of a new formulation of migraine in the nineteenth century, then shows how this context enabled Singer to retrospectively diagnose Hildegard’s migraine and finally examines some of the ways in which this idea has gained popular and academic currency in the second half of the twentieth century. The case of Hildegard’s migraine reminds us of the need to historicise scientific evidence just as rigorously as we historicise our other material and it exposes the cumulative methodological problems that can occur when historians use science, and scientists use history on a casual basis.

2021 ◽  
Vol 13 (20) ◽  
pp. 11467
Author(s):  
Freek Van Doninck ◽  
Johanna Vanderstraeten ◽  
Ine Paeleman ◽  
Luc Van Liedekerke

This teaching case addresses the strategic choices of social entrepreneurs and the issues they face in search of funding. In the heart of Europe’s capital, Brussels, two aspiring entrepreneurs founded Le Champignon de Bruxelles to produce exotic mushrooms. Being true social entrepreneurs, they use a recycled substrate—brewery dredge—to do so, as such, minimizing the distance the mushrooms travel from farm to plate. After the typical “entrepreneur-in-the-basement” start, they are now at a turning point. They established themselves as a serious player in the market, producing over 6000 kg of mushrooms every month. This journey, however, did not come without its challenges. Along the way, they struggled to reconcile their idealistic mindset with the realities of the economic system and adopted a more pragmatic approach in response. At the moment, they are at a decisive moment in the company’s development and are contemplating whether their current business model should be diversified and internationalized.


2011 ◽  
Vol 6 (2) ◽  
pp. 142-156 ◽  
Author(s):  
Dirk Delabastita

This theoretical case study starts from a brief critical discussion of Eurocentrism in translation studies, underscoring the importance of the efforts toward a more inclusive, truly global and culturally balanced approach to translation which are increasingly being made in our field, often under the banner of “the international turn.” However, the rejection of Eurocentrism leaves open a wide range of alternative models and approaches, and this paper aims to show that the search for alternatives is not without its own difficulties. For example, it might be tempting for non-European scholars to derive an alternative way of thinking about translation from translational practices and discourses in their own continent that appear to be at odds with what is perceived as the “European” model of translation. A post-colonial sensibility would seem to make this an extremely attractive proposition. This is the line of thinking which inspired Edwin Gentzler’s Translation and Identity in the Americas. New Directions in Translation Theory (2008). The paper enters into a critical dialogue with Gentzler’s book in order to argue the general thesis that the replacement of one (perceived) continent-based paradigm by another (perceived) continent-based paradigm is not the best way forward, suffering as it does from a range of methodological problems. The best way to overcome Eurocentrism is not to construct and promote an American continentalism (“translation in the American sense”) as an alternative to it, or any other nationally or continentally defined concept of translation, for that matter.


Author(s):  
Jeffrey D. Pugh

The introductory chapter previews the main argument and lays out the scope of the book, defines several of the key concepts that will be used throughout the book (including justifying the usage of the term “migrant” and making explicit the interlinking relationship between human security and peace), provides a brief historical context of the case study of Colombian forced migrants in Ecuador, and presents a rationale for the significance of the book. It also previews the remaining chapters and the key points made in them in order to sketch the progression of the core argument that is developed throughout the book.


2017 ◽  
Vol 26 (1) ◽  
pp. 87-102
Author(s):  
Alys Moody

Beckett's famous claim that his writing seeks to ‘work on the nerves of the audience, not the intellect’ points to the centrality of affect in his work. But while his writing's affective quality is widely acknowledged by readers of his work, its refusal of intellect has made it difficult to take fully into account in scholarly work on Beckett. Taking Beckett's 1967 short prose text Ping as a case study, this essay is an attempt to take the affective qualities of Beckett's writing seriously and to consider the implications of his affectively dense writing for his texts’ relationship to history. I argue that Ping's affect emerges from the rhythms of its prose, producing a highly ‘speakable’ text in which affect precedes interpretation. In Ping, however, this affective rhythmic patterning is portrayed as mechanical, the product of the machinic ‘ping’ that punctuates the text and the text's own mechanical rhythms, demanding the active involvement of the reader. The essay concludes by arguing that Ping's mechanised affect is a specifically historical feeling. Arising from a specifically twentieth-century anxiety about technology's tendency to evacuate ‘natural’ emotion in favour of inhuman affect, it participates in a tradition of affectively resonant but curiously blank or indifferent performances of cyborg embodiment. Read in this historical light, Ping's implication of the reader in the production of its mechanised affect grants it, from our contemporary perspective, an archival quality. At the same time, it asks us to broaden the way in which we understand the Beckettian text's relationship to history, pointing to the existence of a more complex and recursive relationship between literature, its historical moment, and our contemporary moment of reading. Such a post-archival historicism sees texts as generated by but not bound to their historical moments of composition, and understands the moment of reception as an integral, if shifting, part of the text's history.


Infectio ro ◽  
2018 ◽  
Vol 56 (4) (1) ◽  
pp. 9-21
Author(s):  
Ștefan-Sorin Aramă

Irritable bowel syndrome is a frequent digestive condition, with an unclear etiopathogeny. Very probably intestinal dysbiosis plays an important role. For the moment there are no guidelines for treatment. There is scientific evidence for several therapies: modification of diet, non-resorbable antibiotics (rifaximin-α) and probiotics. Giving probiotics after each antibiotic course (an association of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001) supplemented with vitamin B6 may be an optimal strategy.


2021 ◽  
Vol 1 ◽  
pp. 487-496
Author(s):  
Pavan Tejaswi Velivela ◽  
Nikita Letov ◽  
Yuan Liu ◽  
Yaoyao Fiona Zhao

AbstractThis paper investigates the design and development of bio-inspired suture pins that would reduce the insertion force and thereby reducing the pain in the patients. Inspired by kingfisher's beak and porcupine quills, the conceptual design of the suture pin is developed by using a unique ideation methodology that is proposed in this research. The methodology is named as Domain Integrated Design, which involves in classifying bio-inspired structures into various domains. There is little work done on such bio-inspired multifunctional aspect. In this research we have categorized the vast biological functionalities into domains namely, cellular structures, shapes, cross-sections, and surfaces. Multi-functional bio-inspired structures are designed by combining different domains. In this research, the hypothesis is verified by simulating the total deformation of tissue and the needle at the moment of puncture. The results show that the bio-inspired suture pin has a low deformation on the tissue at higher velocities at the puncture point and low deformation in its own structure when an axial force (reaction force) is applied to its tip. This makes the design stiff and thus require less force of insertion.


2021 ◽  
Vol 13 (5) ◽  
Author(s):  
Viktória Mozgai ◽  
Bernadett Bajnóczi ◽  
Zoltán May ◽  
Zsolt Mráv

AbstractThis study details the non-destructive chemical analysis of composite silver objects (ewers, situlas, amphora and casket) from one of the most significant late Roman finds, the Seuso Treasure. The Seuso Treasure consists of fourteen large silver vessels that were made in the fourth–early fifth centuries AD and used for dining during festive banquets and for washing and beautification. The measurements were systematically performed along a pre-designed grid at several points using handheld X-ray fluorescence analysis. The results demonstrate that all the objects were made from high-quality silver (above 90 wt% Ag), with the exception of the base of the Geometric Ewer B. Copper was added intentionally to improve the mechanical properties of soft silver. The gold and lead content of the objects shows constant values (less than 1 wt% Au and Pb). The chemical composition as well as the Bi/Pb ratio suggests that the parts of the composite objects were manufactured from different silver ingots. The ewers were constructed in two ways: (i) the base and the body were made separately, or (ii) the ewer was raised from a single silver sheet. The composite objects were assembled using three methods: (i) mechanical attachment; (ii) low-temperature, lead-tin soft solders; or (iii) high-temperature, copper-silver hard solders. Additionally, two types of gilding were revealed by the XRF analysis, one with remnants of mercury, i.e. fire-gilding, and another type without remnants of mercury, presumably diffusion bonding.


2019 ◽  
Vol 100 ◽  
pp. 00070 ◽  
Author(s):  
Elżbieta Romanik ◽  
Yaroslav Bezyk ◽  
Marcin Pawnuk ◽  
Urszula Miller ◽  
Agnieszka Grzelka

Odour concentration measurements in a chosen industrial source were made in this study using the method of dynamic olfactometry. The two different scenarios considered the variation of the odour emission rate as input for the dispersion model were compared for the period 2017 (before installation of the equipment for gas treatment) and 2018 (after implementation of purifying technologies). In this paper the odour impact range was determined by applying model calculations conducted in the Polish reference dispersion model – OPERAT FB software for the grid size 2 x 2 km. The conducted research shows a significant improvement in the odour impact range of chosen industrial source in year 2018 compared to 2017.


2002 ◽  
Vol os9 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Raman Bedi ◽  
Jackie A Champion ◽  
Roger Davies

Introduction In order to promote training and education in special-needs dentistry an attempt was made to introduce problem-based learning (PBL) as a method of postgraduate dental education. The aim of this paper was to review the principles of PBL and report on a case study using this methodology. Method The case study was of a PBL session, on the subject of ‘problems of obtaining appropriate dental care for people with epilepsy’, undertaken at a national conference. Delegates were asked to complete a pre- and post-session questionnaire on PBL and their attitudes to the session. Results The session received a mixed response. Only 33 (35%) thought the session was valuable and only 20 (31%) thought it was better than conventional teaching methods and yet over half (55%) said they would like to attend more PBL in special-needs dentistry. Professionals complementary to dentistry were more likely to find the PBL session of value and to prefer the method to a more conventional format than dentists were (chi-square=5.5, df=1, p<0.05 and chi-square=5.9, df=1, p<0.05 respectively). Conclusion Valuable feedback was received from delegates. This will enable improvements to be made in future courses so that the effectiveness of PBL can be optimised.


2005 ◽  
Vol 32 (4) ◽  
pp. 719-725 ◽  
Author(s):  
Joyce Li Zhang ◽  
K Ponnambalam

This paper describes the implementation of a new solution approach — Fletcher-Ponnambalam model (FP) — for risk management in hydropower system under deregulated electricity market. The FP model is an explicit method developed for the first and second moments of the storage state distributions in terms of moments of the inflow distributions. This method provides statistical information on the nature of random behaviour of the system state variables without any discretization and hence suitable for multi-reservoir problems. Also avoiding a scenario-based optimization makes it computationally inexpensive, as there is little growth to the size of the original problem. In this paper, the price uncertainty was introduced into the FP model in addition to the inflow uncertainty. Lake Nipigon reservoir system is chosen as the case study and FP results are compared with the stochastic dual dynamic programming (SDDP). Our studies indicate that the method could achieve optimum operations, considering risk minimization as one of the objectives in optimization.Key words: reservoir operations, explicit method, uncertainty, stochastic programming, risk.


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