scholarly journals Iron and zinc concentrations in peanut (Arachis hypogaea L.) seeds and their relationship with other nutritional and yield parameters

2014 ◽  
Vol 153 (6) ◽  
pp. 975-994 ◽  
Author(s):  
PASUPULETI JANILA ◽  
S. N. NIGAM ◽  
R. ABHISHEK ◽  
V. ANIL KUMAR ◽  
S. S. MANOHAR ◽  
...  
Keyword(s):  
Arachis Hypogaea ◽  
Positive Association ◽  
Cost Effective ◽  
Breeding Programme ◽  
Significant Positive Association ◽  
Trade Offs ◽  
Iron And Zinc ◽  
Zinc Concentrations ◽  
Micronutrient Malnutrition ◽  
Stable Performance

SUMMARYBiofortification (delivery of micronutrients via micronutrient-dense crops) can be achieved through plant breeding and offers a cost-effective and sustainable approach to fighting micronutrient malnutrition. The present study was conducted to facilitate the initiation of a breeding programme to improve the concentration of iron (Fe) and zinc (Zn) in peanut (Arachis hypogaea L.) seeds. The experiment was conducted with 64 diverse peanut genotypes for 2 years in eight different environments at the International Crops Research Institute for the Semi-Arid Tropics, Patancheru, India to assess the genetic variation for Fe and Zn concentrations in peanut seeds and their heritability and correlations with other traits. Significant differences were observed among the genotypes and environments for Fe (33–68 mg/kg), Zn (44–95 mg/kg), protein (150–310 mg/g) and oil (410–610 mg/g) concentration in seeds and their heritability was high, thus indicating the possibility of improving them through breeding. As seen in other plants, a significant positive association between concentrations of Fe and Zn was observed. Trade-offs between pod yield and Fe and Zn concentrations were not observed and the same was also true for oil content. Besides being high yielding, genotypes ICGV 06099 (57 mg/kg Fe and 81 mg/kg Zn) and ICGV 06040 (56 mg/kg Fe and 80 mg/kg Zn) had stable performance for Fe and Zn concentrations across environments. These are the ideal choices for use as parents in a breeding programme and in developing mapping populations.

scholarly journals Heterosis Effects on Genetic Biofortification of Grain Iron and Zinc in Pearl Millet (Pennisetumglacum L.).

2019 ◽  
Author(s):  
T. Shobha Rani ◽  
G. Anil Kumar ◽  
K. Sravanti ◽  
C.V. Sameer Kumar ◽  
S. Maheswaramma ◽  
...  
Keyword(s):  
Pearl Millet ◽  
Agronomic Traits ◽  
Cost Effective ◽  
Genetic Enhancement ◽  
Content Ratio ◽  
Cost Effective Approach ◽  
Iron And Zinc ◽  
Grain Crop ◽  
Micronutrient Malnutrition ◽  
Breeding Efficiency

Pearl millet is traditionally a small grain crop, adapted to marginal environments. Micronutrient malnutrition arising from deficiency of one or more essential micronutrients. Crop biofortification is a sustainable and cost-effective approach to address micro nutrient malnutrition, especially in the developing world. It refers to the development of micronutrient-dense staple crops using conventional breeding practices. Availability of traits of concern in improved genetic background greatly enhances the breeding efficiency for the target trait combining with other desirable agronomic traits. The main objective of this study was to determine heterosis for Fe and Zn by using line x tester analysis. Low level of heterosis over mid-parent (MP) for grain Fe and Zn and no hybrid with significant heterosis over better-parent (BP) for Fe and Zn, suggested that there would be little opportunity, if any, to exploit heterosis for these traits. This would also mean that to breed high Fe and high Zn hybrids, these traits will have to breed into both parental lines of hybrids.Based on the results, it can be concluded that there are good prospects of genetic enhancement for grain Fe and Zn content ratio interm of hybrid development in pearl millet.

scholarly journals Breeding Biofortified Pearl Millet Varieties and Hybrids to Enhance Millet Markets for Human Nutrition

Agriculture ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 106 ◽  
Author(s):  
Mahalingam Govindaraj ◽  
Kedar Nath Rai ◽  
Binu Cherian ◽  
Wolfgang Helmut Pfeiffer ◽  
Anand Kanatti ◽  
...  
Keyword(s):  
Pearl Millet ◽  
Distribution System ◽  
Cost Effective ◽  
Nutritional Intervention ◽  
Market Demand ◽  
Tropical Regions ◽  
The Public ◽  
Public Distribution System ◽  
Iron And Zinc ◽  
Micronutrient Malnutrition

Pearl millet is an important food crop in the arid and semi-arid tropical regions of Africa and Asia. Iron and zinc deficiencies are widespread and serious public health problems worldwide, including in India and Africa. Biofortification is a cost-effective and sustainable agricultural strategy to address this problem. The aim of this review is to provide the current biofortification breeding status and future directions of the pearl millet for growing nutrition markets. Research on the pearl millet has shown that a large genetic variability (30–140 mg kg−1 Fe and 20–90 mg kg−1 Zn) available in this crop can be effectively utilized to develop high-yielding cultivars with high iron and zinc densities. Open-pollinated varieties (Dhanashakti) and hybrids (ICMH 1202, ICMH 1203 and ICMH 1301) of pearl millet with a high grain yield and high levels of iron (70–75 mg kg−1) and zinc (35–40 mg kg−1) densities have been developed and released first in India. Currently, India is growing > 70,000 ha of biofortified pearl millet, and furthermore more pipeline cultivars are under various stages of testing at the national (India) and international (west Africa) trials for a possible release. Until today, no special markets existed to promote biofortified varieties and hybrids as no incentive price to products existed to address food and nutritional insecurity simultaneously. The market demand is likely to increase only after an investment in crop breeding and the integration into the public distribution system, nutritional intervention schemes, private seed and food companies with strong mainstreaming nutritional policies. The following sections describe various aspects of breeding and market opportunity for addressing micronutrient malnutrition.

Perceived Overprotection and Its Association With Quality of Life in Dementia

GeroPsych ◽  
2019 ◽  
Vol 32 (3) ◽  
pp. 125-134
Author(s):  
Mechthild Niemann-Mirmehdi ◽  
Andreas Häusler ◽  
Paul Gellert ◽  
Johanna Nordheim
Keyword(s):  
Quality Of Life ◽  
Patient Autonomy ◽  
Positive Association ◽  
Well Being ◽  
Negative Association ◽  
Significant Positive Association ◽  
Cross Sectional ◽  
People With Dementia ◽  
Mental Well Being

Abstract. To date, few studies have focused on perceived overprotection from the perspective of people with dementia (PwD). In the present examination, the association of perceived overprotection in PwD is examined as an autonomy-restricting factor and thus negative for their mental well-being. Cross-sectional data from the prospective DYADEM study of 82 patient/partner dyads (mean age = 74.26) were used to investigate the association between overprotection, perceived stress, depression, and quality of life (QoL). The analyses show that an overprotective contact style with PwD has a significant positive association with stress and depression, and has a negative association with QoL. The results emphasize the importance of avoiding an overprotective care style and supporting patient autonomy.

The Nexus Between Urbanisation and Human Empowerment: Income Group Based Findings of Bidirectional Causality

2019 ◽  
Vol 64 (1) ◽  
pp. 5-15
Author(s):  
Christos Kollias ◽  
Panayiotis Tzeremes
Keyword(s):  
Human Rights ◽  
Positive Association ◽  
Income Group ◽  
Academic Discourse ◽  
Access To Education ◽  
Democratic Institutions ◽  
Significant Positive Association ◽  
Public Action ◽  
Income Groups ◽  
Democratic Rule

Abstract The economic and social drivers of democratisation and the emergence and establishment of democratic institutions are longstanding themes of academic discourse. Within this broad body of literature, it has been argued that the process of urbanisation is also conducive to the emergence and consolidation of democracy through a number of different channels. Cities offer better access to education and facilitate organised public action and the demand for more democratic rule and respect of human rights. The nexus between urbanisation and human rights is the theme that is taken up in the present paper. Using a sample of 123 countries for the period 1981–2011, the paper examines empirically the association between urbanisation and human empowerment using the Cingranelli-Richards Index. In broad terms, the findings reported herein do not point to a strong nexus across all income groups. Nevertheless, there is evidence suggesting the presence of such a statistically significant positive association in specific cases.

Empirical analysis on corporate environmental performance and environmental disclosure in an emerging market context

2020 ◽  
Vol 15 (6) ◽  
pp. 1061-1082 ◽  
Author(s):  
Merve Acar ◽  
Hüseyin Temiz
Keyword(s):  
Environmental Performance ◽  
Emerging Market ◽  
Positive Association ◽  
Corporate Environmental Performance ◽  
Tobit Regression ◽  
Environmental Reporting ◽  
Environmental Disclosure ◽  
Significant Positive Association ◽  
Content Type ◽  
Environmental Disclosures

PurposeThe purpose of this study is to investigate the association between environmental performance of firms and the level of voluntary environmental disclosure in emerging markets.Design/methodology/approachWe used tobit regression OLS and t-test methods to reveal the association between environmental performance and the level of voluntary environmental disclosure.FindingsWe find a significant positive association between the level of discretionary environmental disclosures and corporate environmental performance. The result is in line with the arguments of economics disclosure theory that argues environmentally good performers disclose more.Practical implicationsMany of the environmentally good firms in Turkey are also listed in the “BIST Sustainability Index,” and this situation can be the result of the relative power of external regulations. Accordingly, it can be suggested to increase the community and governmental pressures for environmental reporting but also gives importance to increase intrinsic motivations for companies to engage in disclosure practices.Originality/valueThis study shed light on relation between environmental performance and environmental disclosure in an emerging market context. Also, it is revisited that the relation between environmental performance and the level of environmental disclosure by testing two different predictions on the level of environmental disclosures.

scholarly journals Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature

Medicina ◽  
2019 ◽  
Vol 55 (8) ◽  
pp. 458 ◽  
Author(s):  
Bonanni ◽  
Gualtieri ◽  
Lester ◽  
Falcone ◽  
Nardella ◽  
...  
Keyword(s):  
Suicidal Behavior ◽  
Affective Disorders ◽  
Suicide Attempts ◽  
Positive Association ◽  
Negative Association ◽  
Schizophrenia Spectrum Disorders ◽  
Post Traumatic Stress ◽  
Significant Positive Association ◽  
Search Terms ◽  
Schizophrenia Spectrum

Background and Objectives: At present, data collected from the literature about suicide and anhedonia are controversial. Some studies have shown that low levels of anhedonia are associated with serious suicide attempts and death by suicide, while other studies have shown that high levels of anhedonia are associated with suicide. Materials and Methods: For this review, we searched PubMed, Medline, and ScienceDirect for clinical studies published from 1 January 1990 to 31 December 2018 with the following search terms used in the title or in the abstract: “anhedonia AND suicid*.” We obtained a total of 155 articles; 133 items were excluded using specific exclusion criteria, the remaining 22 articles included were divided into six groups based on the psychiatric diagnosis: mood disorders, schizophrenia spectrum disorders, post-traumatic stress disorder (PTSD), other diagnoses, attempted suicides, and others (healthy subjects). Results: The results of this review reveal inconsistencies. Some studies reported that high anhedonia scores were associated with suicidal behavior (regardless of the diagnosis), while other studies found that low anhedonia scores were associated with suicidal behavior, and a few studies reported no association. The most consistent association between anhedonia and suicidal behavior was found for affective disorders (7 of 7 studies reported a significant positive association) and for PTSD (3 of 3 studies reported a positive association). In the two studies of patients with schizophrenia, one found no association, and one found a negative association. For patients who attempted suicide (undiagnosed), one study found a positive association, one a positive association only for depressed attempters, and one a negative association. Conclusions: We found the most consistent positive association for patients with affective disorders and PTSD, indicating that the assessment of anhedonia may be useful in the evaluation of suicidal risk.

scholarly journals Autophagic Markers in Chordomas: Immunohistochemical Analysis and Comparison with the Immune Microenvironment of Chordoma Tissues

Cancers ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 2169
Author(s):  
Georgia Karpathiou ◽  
Maroa Dridi ◽  
Lila Krebs-Drouot ◽  
François Vassal ◽  
Emmanuel Jouanneau ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Immune Cells ◽  
Immune Cell ◽  
Positive Association ◽  
Immunohistochemical Analysis ◽  
Vascular Density ◽  
Immune Microenvironment ◽  
Significant Positive Association ◽  
Sequestosome 1 ◽  
Cell Expression

Chordomas are notably resistant to chemotherapy. One of the cytoprotective mechanisms implicated in chemoresistance is autophagy. There are indirect data that autophagy could be implicated in chordomas, but its presence has not been studied in chordoma tissues. Sixty-one (61) chordomas were immunohistochemically studied for autophagic markers and their expression was compared with the expression in notochords, clinicopathological data, as well as the tumor immune microenvironment. All chordomas strongly and diffusely expressed cytoplasmic p62 (sequestosome 1, SQSTM1/p62), whereas 16 (26.2%) tumors also showed nuclear p62 expression. LC3B (Microtubule-associated protein 1A/1B-light chain 3B) tumor cell expression was found in 44 (72.1%) tumors. Autophagy-related 16‑like 1 (ATG16L1) was also expressed by most tumors. All tumors expressed mannose-6-phosphate/insulin-like growth factor 2 receptor (M6PR/IGF2R). LC3B tumor cell expression was negatively associated with tumor size, while no other parameters, such as age, sex, localization, or survival, were associated with the immunohistochemical factors studied. LC3B immune cell expression showed a significant positive association with programmed death-ligand 1 (PD-L1)+ immune cells and with a higher vascular density. ATG16L1 expression was also positively associated with higher vascular density. Notochords (n = 5) showed different immunostaining with a very weak LC3B and M6PR expression, and no p62 expression. In contrast to normal notochords, autophagic factors such as LC3B and ATG16L1 are often present in chordomas, associated with a strong and diffuse expression of p62, suggesting a blocked autophagic flow. Furthermore, PD-L1+ immune cells also express LC3B, suggesting the need for further investigations between autophagy and the immune microenvironment.

scholarly journals Association between Health Practice and Food Stockpiling for Disaster

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1414
Author(s):  
Moeka Harada ◽  
Rie Kobayashi ◽  
Jun Oka ◽  
Nobuyo Tsuboyama-Kasaoka
Keyword(s):  
High Risk ◽  
Online Survey ◽  
Positive Association ◽  
Good Health ◽  
Food Shortage ◽  
Multivariable Logistic Regression Analysis ◽  
Health Practices ◽  
Health Practice ◽  
Significant Positive Association ◽  
Good Score

In this study investigated the association between health practices and food stockpiling for disasters in predicted areas with a high risk of food shortage due to the Nankai Trough earthquake. A survey was conducted during 18–20 December 2019 using a self-administered web-based questionnaire. In total, 1200 individuals registered with an online survey company participated in the study. The association between health practices and food stockpiling status was analyzed (n = 998). 59.1% of participants had a poor Breslow’s seven health practice scores (BHPS), 32.9% had a moderate score, and 8.0% had a good score. Multivariable logistic regression analysis revealed that higher BHPS had a significantly higher prevalence of food stockpiling. Additionally, the interrupted group had the highest percentage of participants with low BHPS. Lower BHPS was significantly associated with interrupted stockpiled in the adjusted models. Among the seven health practices, the odds ratio of the “eating breakfast” practice was high. There was a significant positive association between higher health practice scores and food stockpiling for disasters in areas with a high risk of food shortage due to the predicted earthquake. Particularly, it was clarified that individuals who had fewer good health practices were associated with ending up interrupting food stockpiling.

scholarly journals Granulocyte Colony Stimulating Factor Expression in Breast Cancer and Its Association with Carbonic Anhydrase IX and Immune Checkpoints

Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1022
Author(s):  
Shawn C. Chafe ◽  
Nazia Riaz ◽  
Samantha Burugu ◽  
Dongxia Gao ◽  
Samuel C. Y. Leung ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Carbonic Anhydrase ◽  
Immune Checkpoint ◽  
Positive Association ◽  
Carcinoma Cells ◽  
Carbonic Anhydrase Ix ◽  
Granulocyte Colony Stimulating Factor ◽  
Colony Stimulating Factor ◽  
Significant Positive Association ◽  
Stimulating Factor

Purpose: Granulocyte colony-stimulating factor (G-CSF) and hypoxia modulate the tumour immune microenvironment. In model systems, hypoxia-induced carbonic anhydrase IX (CAIX) has been associated with G-CSF and immune responses, including M2 polarization of macrophages. We investigated whether these associations exist in human breast cancer specimens, their relation to breast cancer subtypes, and clinical outcome. Methods: Using validated protocols and prespecified scoring methodology, G-CSF expression on carcinoma cells and CD163 expression on tumour-associated macrophages were assayed by immunohistochemistry and applied to a tissue microarray series of 2960 primary excision specimens linked to clinicopathologic, biomarker, and outcome data. Results: G-CSFhigh expression showed a significant positive association with ER negativity, HER2 positivity, presence of CD163+ M2 macrophages, and CAIX expression. In univariate analysis, G-CSFhigh phenotype was associated with improved survival in non-luminal cases, although the CAIX+ subset had a significantly adverse prognosis. A significant positive association was observed between immune checkpoint biomarkers on tumour-infiltrating lymphocytes and both G-CSF- and CAIX-expressing carcinoma cells. Immune checkpoint biomarkers correlated significantly with favourable prognosis in G-CSFhigh/non-luminal cases independent of standard clinicopathological features. Conclusions: The prognostic associations linking G-CSF to immune biomarkers and CAIX strongly support their immunomodulatory roles in the tumour microenvironment.

Sign in / Sign up

Export Citation Format

Share Document