Socio-economic status, family disruption and residential stability in childhood: relation to onset, recurrence and remission of major depression

2003 ◽  
Vol 33 (8) ◽  
pp. 1341-1355 ◽  
Author(s):  
S. E. GILMAN ◽  
I. KAWACHI ◽  
G. M. FITZMAURICE ◽  
S. L. BUKA

Background. Childhood adversity significantly increases the risk of depression, but it is unclear whether this risk is most pronounced for depression occurring early in life. In the present study, we examine whether three aspects of childhood adversity – low socio-economic status (SES), family disruption, and residential instability – are related to increased risk of depression during specific stages of the life course. We also examine whether these aspects of childhood adversity are related to the severity of depression.Method. A sample of 1089 of the 4140 births enrolled in the Providence, Rhode Island cohort of the National Collaborative Perinatal Project was interviewed between the ages of 18 and 39. Measures of parental SES, childhood family disruption and residential instability were obtained upon mother's enrolment and at age 7. Age at onset of major depressive episode, lifetime number of depressive episodes, and age at last episode were ascertained via structured diagnostic interviews. Survival analysis was used to identify risk factors for depression onset and remission and Poisson regression was used to model the recurrence rate of depressive episodes.Results. Low parental SES, family disruption and a high level of residential instability, defined as three or more family moves, were related to elevated lifetime risks of depression; the effects of family disruption and residential instability were most pronounced on depression onset by age 14. Childhood adversity was also related to increased risk of recurrence and reduced likelihood of remission.Conclusions. Childhood social disadvantage significantly influences risk of depression onset both in childhood and in adulthood. Early childhood adversity is also related to poor prognosis.

Author(s):  
Christopher Edet Ekpenyong ◽  
Abasifreke Godwin Asuquo

Background:  The prevalence of childhood obesity (COB) in the developing world is currently high and is rising rapidly. Unlike developed countries, studies evaluating the association between parental socio-economic status (SES) and risk of COB in developing countries are limited. Besides, the association varies across country and race/ethnicity and changes overtime. The aim of this study was to assess the association between parental SES and life style habits (LSHs) and risk of COB in Uyo, Southern Nigeria. Methods: Five hundred pupils and the corresponding number of parents were examined between April and September 2018 using socio-demographic/LSHs assessment questionnaire and body mass index (BMI) evaluation. Data analysis was performed and frequencies and percentages were computed.  Associations between SES and LSHs of parents and risk of COW/COB were evaluated using multiple logistic regression analysis. Odds ratios and corresponding 95% confidence intervals were estimated. Results: The prevalence of COW and COB was 3.4% and 16% respectively. The risk of COW/COB was higher among children whose parents had high level of education (OR=1.81, C.I=1.985-3.327,P=0.046), high level of income(OR=16.07, C.I=3.773-68.455,P=0.0001), employed(OR=1.138,C.I=0.157-12.057) and poor dietary habits. High level of physical activity of fathers and high income level of mothers decreased the risk of COW/COB. Conclusion:  High SES and poor LSHs of parents are associated with increased risk of COW/COB. Interventions necessary to reduce high prevalence of COW/COB in our cities and other developing countries should include among other risk factors parental SES and LSHs.


2013 ◽  
Vol 202 (4) ◽  
pp. 269-276 ◽  
Author(s):  
Eamon J. McCrory ◽  
Stéphane A. De Brito ◽  
Philip A. Kelly ◽  
Geoffrey Bird ◽  
Catherine L. Sebastian ◽  
...  

BackgroundChildhood adversity is associated with significantly increased risk of psychiatric disorder. To date, functional magnetic resonance imaging (fMRI) studies of children have mainly focused on institutionalisation and investigated conscious processing of affect.AimsTo investigate neural response to pre-attentively presented affect cues in a community sample of children with documented experiences of maltreatment in the home.MethodA masked dot-probe paradigm involving pre-attentive presentation of angry, happy and neutral facial expressions was employed. Eighteen maltreated children were compared with 23 carefully matched non-maltreated peers.ResultsIncreased neural response was observed in the right amygdala for pre-attentively presented angry and happy faces in maltreated v. non-maltreated children. Level of amygdala activation was negatively associated with age at onset for several abuse subtypes.ConclusionsMaltreatment is associated with heightened neural response to positive and negative facial affect, even to stimuli outside awareness. This may represent a latent neural risk factor for future psychiatric disorder.


2020 ◽  
Vol 32 (11) ◽  
pp. 2319-2327 ◽  
Author(s):  
Per Wändell ◽  
Axel C. Carlsson ◽  
Xinjun Li ◽  
Danijela Gasevic ◽  
Jan Sundquist ◽  
...  

Abstract Objectives Association between socio-demographic factors and dementia risk is studied in general but not for atrial fibrillation (AF) patients. Methods We studied AF patients ≥ 45 years in Sweden 1998–2012 (n = 537,513) using the Total Population Register for socio-demographic factors, the Swedish Cause of Death Register, and the National Patient Register (NPR) for incident dementia. Cox regression with hazard ratios (HR) and 95% confidence intervals (CI) was used for the association between exposure and outcome, adjusting for age and comorbidities. Results Totally 30,332 patients (5.6%) were diagnosed with dementia during the follow-up (mean 5.4 years). Of these, 14,097 were men (4.9%) and 16,235 were women (6.5%). Lower educational levels (reference: highest level) were associated with increased dementia, HRs (95% CI) for basic school for men 1.23 (1.18–1.29) and women 1.36 (1.30–1.42), and middle-level school for men 1.17 (1.11–1.22) and women 1.28 (1.22–1.34). Divorced men and women (reference: married) showed increased risk of dementia, HR 1.07 (1.01–1.13) and 1.12 (1.06–1.18), respectively, while widowed men showed lower risk, HR 0.84 (0.80–0.88). High deprivation neighborhood socio-economic status (NSES; reference: medium level) was associated with increased dementia in men, HR 1.11 (1.05–1.17), and low deprivation neighborhood socio-economic status (NSES) with increased dementia in men and women, HR 1.12 (1.06–1.18) and 1.18 (1.12–1.24), respectively. Conclusions Some results were expected, i.e. association between lower educational level and dementia. The higher risk of dementia in low deprivation NSES-areas could be due to a higher awareness about dementia, and subsequent earlier diagnosis and treatment of dementia.


2018 ◽  
Vol 23 (suppl_1) ◽  
pp. e37-e38
Author(s):  
Deliwe Ngwezi ◽  
Lisa Hornberger ◽  
Jesus Serrano-Lomelin ◽  
Charlene Nielsen ◽  
Deborah Fruitman ◽  
...  

Abstract BACKGROUND Evidence is emerging suggesting associations between environmental pollutants, socio-economic status (SES) and congenital heart disease (CHD); however, it is still inconclusive. Furthermore, it has been documented in environmental injustice studies that people with low socio-economic status are disproportionately vulnerable to environmental hazards and therefore are victims of a double jeopardy. OBJECTIVES We sought to explore the effect of exposure to groups of developmental toxicants (DTs) and SES on CHD development in urban and rural Alberta. DESIGN/METHODS We identified 2,413 CHD cases and postal codes (PC) from echocardiographic databases (2003–2010). We used previously defined groups of DTs comprised of: 1- organics and gases, 2-organics and 3-heavy metals. Exposure was assigned to each PC as the sum of the product of multiplying amounts of DTs (tonnes) emitted from any industrial facility within 10 km radius during the whole study period, by the inverse distance from the facility to the centroid of the PC. Exposures were categorized into deciles from 1(lowest) to 10 (highest) for group 1 DTs and tertiles (1=lowest to 3 =highest), for groups 2 and 3 DTs and the SES index. Poisson regression models were used to calculate risk ratios and 95% CI, adjusted for SES index or DTs and traffic-related surrogates (NO2, PM2.5). RESULTS Adjusted Effect of DT Exposure: Group 1 DT showed increased risk in urban and rural regions in the 10th decile of exposure, aRR=1.85(1.5, 2.3) and 2.67(1.04, 6.8, respectively). Group 2 DT risk was increased only in urban 3rd tertile, RR=1.45(1.3, 1.6). Group 3 DTs were associated with an increased risk in urban and rural regions in the 3rd tertile of exposure [aRR=1.16(1.04, 1.3), and 2.8(1.14, 7.1, respectively)]. Adjusted Effect of SES: SES was independently associated with an increased risk of CHD in urban lowest tertile, [aRR=1.13(1.0, 1.3)] and rural lowest and middle SES tertile, [aRR=2.9(1.9, 4.8) and 1.6(1.1, 2.6), respectively]. CONCLUSION High exposures to groups of DTs and SES were independently associated with an increased risk of CHD in urban and rural Alberta. This suggests that neighborhood SES in Alberta does not impose a disproportional exposure to DTs. Furthermore, SES had a greater impact in rural compared to urban regions. We would like to explore for interactions between the SES and DT exposures and to determine if there is environmental injustice in Alberta.


2020 ◽  
pp. 1-31
Author(s):  
Nicole I. Larson

Abstract To inform programmes and policies that promote health equity, it is essential to monitor the distribution of nutritional problems among young individuals. Common nutritional problems include overall low diet quality, the underconsumption and overconsumption of certain dietary components, unhealthy meal and snack patterns, problematic feeding practices and disordered eating. The objective of the present narrative review was to summarise recent evidence of disparities among US children (2–19 years) according to age, sex, socio-economic status, ethnicity/race and rural–urban location. Searches in PubMed® and MEDLINE® were completed to identify peer-reviewed research studies published between January 2009 and January 2019. Findings from the ninety-nine reviewed studies indicate adolescent females, young individuals from lower socio-economic households and individuals who identify as non-Hispanic Black race are particularly vulnerable populations for whom targeted strategies should be developed to address evidence of increased risk with regards to multiple aspects of nutritional wellbeing. Limitations of the existing evidence relate to the accuracy of self-reported dietary data; the need for consistent definitions of disordered eating; the focus on individual dietary components v. patterns; the complexities of categorising socio-economic status, ethnicity/race, and rural and urban areas; and the cross-sectional, observational nature of most research designs. There is an urgent need for research to address these limitations and fill a large gap in evidence on rural–urban differences in nutritional problems. It will further be important for future studies to build greater understanding of how nutritional problems cluster among population groups.


Author(s):  
Majid TAHERI ◽  
Mohammad TAVAKOL ◽  
Mohammad Esmaeil AKBARI ◽  
Amir ALMASI-HASHIANI ◽  
Mahmoud ABBASI

Background: Despite our awareness of the significant effect of Social Determinant of Health (SDoH) such as Socio Economic Status (SES), income and education on breast cancer survival, there was a serious lack of information about the effect of different level of these factors on breast cancer survival. So far, no meta-analysis has been conducted with this aim, but this gap was addressed by this meta-analysis. Methods: Main electronic databases such as PubMed, Web of Science, and Scopus were investigated up to January 2019. Epidemiological studies focusing on the association between SDoH and breast cancer were singled out. Q-test and I2 statistic were used to study the heterogeneity across studies. Begg's and Egger's tests were applied to explore the likelihood of the publication bias. The results were reported as hazard ratio (HR) with 95% confidence intervals (CI) through a random-effects model. Results: We identified 7,653 references and included 25 studies involving 1,497,881 participants. The HR estimate of breast cancer survival was 0.82 (0.67, 0.98) among high level of SES, 0.82 (0.70, 0.94) among high level of income and 0.72 (0.66, 0.78) among academic level of education. Conclusion: The SES, income, and education were associated with breast cancer survival, although the association was not very strong. However, there was a significant association between the levels of these factors and breast cancer survival.


2011 ◽  
Vol 41 (9) ◽  
pp. 1857-1866 ◽  
Author(s):  
A. Steptoe ◽  
G. J. Molloy ◽  
N. Messerly-Bürgy ◽  
A. Wikman ◽  
G. Randall ◽  
...  

BackgroundThe determinants of depression following acute coronary syndrome (ACS) are poorly understood. Triggering of ACS by emotional stress and low socio-economic status (SES) are predictors of adverse outcomes. We therefore investigated whether emotional triggering and low SES predict depression and anxiety following ACS.MethodThis prospective observational clinical cohort study involved 298 patients with clinically verified ACS. Emotional stress was assessed for the 2 h before symptom onset and compared with the equivalent period 24 h earlier using case-crossover methods. SES was defined by household income and education. Depression was measured with the Beck Depression Inventory and the Hamilton Rating Scale for Depression and anxiety with the Hospital Anxiety and Depression Scale 3 weeks after ACS and again at 6 and 12 months. Age, gender, ethnicity, marital status, the Global Registry of Acute Coronary Events risk score, duration of hospital stay and history of depression were included as covariates.ResultsEmotional stress during the 2-h hazard period was associated with increased risk of ACS (odds ratio 1.88, 95% confidence interval 1.01–3.61). Both low income and emotional triggering predicted depression and anxiety at 3 weeks and 6/12 months independently of covariates. The two factors interacted, with the greatest depression and anxiety in lower income patients who experienced acute emotional stress. Education was not related to depression.ConclusionsPatients who experience acute emotional stress during their ACS and are lower SES as defined by current affluence and access to resources are particularly vulnerable to subsequent depression and anxiety.


Author(s):  
Deeptangshu Sarma ◽  
Jahanara Jahanara

SES (socio-economic status) is a measurement of an entity's economic and social position in comparison to others in society. It has an impact on resource accessibility, livelihood patterns, food and nutritional security, and so on. Knowledge, attitude, perception, adoption, change-proneness, level of aspiration, economic motivation and other psychological and behavioural components of a sample are frequently predicted. The present study tried to investigate about the socio economic status of the marginal and small farmers with special reference to Schedule caste and schedule tribe farmers in Kamrup district of Assam. Descriptive research design has been used . Data of 120 respondents were collected with the help of pre-structured questionnaire and personal interview. The study was conducted in 5 villages in Kamrup district of Assam in the year 2021.Thirteen variables were selected viz. category Gender, age, caste, education, annual income, occupation, social participation, types of house, land holding , Mass media exposure, farm power, material possessed, Extension contact were taken into account. Equal numbers of respondents were taken from SC and ST. 64.2% of the respondents were male. Majority of them were under 30 years old. Majority of the percentage had primary level of education, along with medium annual income. The overall SES category was medium level with 48.3% and low level 32.5% of SES category, 19.2% high level.


2004 ◽  
Vol 35 (3) ◽  
pp. 353-365 ◽  
Author(s):  
DANIEL N. KLEIN ◽  
PETER M. LEWINSOHN ◽  
PAUL ROHDE ◽  
JOHN R. SEELEY ◽  
THOMAS M. OLINO

Background. There is a large literature indicating that the offspring of mothers with Major Depressive Disorder (MDD) are at increased risk for depression. However, much less is known about the effects of paternal MDD on offspring psychopathology.Method. We addressed this issue using a large community sample of parents and their adolescent and young adult offspring (n=775). Parents and offspring were independently assessed with semi-structured diagnostic interviews. Offspring were interviewed three times from mid-adolescence to age 24 years.Results. Maternal MDD was significantly associated with offspring MDD. Paternal MDD was also significantly associated with MDD in offspring, but only among offspring with depressive episodes of moderate or greater severity. These effects persisted after controlling for socio-economic status, family intactness, and non-mood disorders in both parents. Rates of MDD were particularly elevated in offspring of mothers and fathers with early-onset MDD, and offspring of fathers with recurrent MDD. The magnitude of the associations between MDD in parents and offspring was generally in the small-to-medium range.Conclusions. These results confirm previous findings of elevated risk of MDD in the offspring of depressed mothers. In addition, the results suggest that MDD in fathers is associated with increased risk of depression in offspring, but that it is limited to MDD episodes in offspring of moderate or greater severity.


2011 ◽  
Vol 23 (4) ◽  
pp. 1017-1037 ◽  
Author(s):  
Paul O. Wilkinson ◽  
Ian M. Goodyer

AbstractChildhood adversity is associated with increased risk for onset of depressive episodes. This review will present evidence that allostatic overload of the hypothalamic–pituitary–adrenal axis (HPAA) partially mediates this association. The HPAA is the physiological system that regulates levels of the stress hormone cortisol. First, data from animals and humans has shown that early environmental adversity is associated with long-term dysregulation of the HPAA. This may occur due to permanent epigenetic modification of the glucocorticoid receptor. Second, data from humans has demonstrated that HPAA dysregulation is associated with increased risk of future depression onset in healthy individuals, and pharmacological correction of HPAA dysregulation reduces depressive symptoms. HPAA dysregulation may result in corticoid-mediated abnormalities in neurogenesis in early life and/or neurotoxicity on neural systems that subserve emotion and cognition.


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