scholarly journals Prevalence and risk factors for colonization of Clostridium difficile among adults living near livestock farms in the Netherlands

2017 ◽  
Vol 145 (13) ◽  
pp. 2745-2749 ◽  
Author(s):  
T. P. ZOMER ◽  
E. VAN DUIJKEREN ◽  
C. C. H. WIELDERS ◽  
C. VEENMAN ◽  
P. HENGEVELD ◽  
...  

SUMMARYA cross-sectional study was performed among 2494 adults not living or working on a farm to assess prevalence of Clostridium difficile (CD) colonization and risk factors in a livestock dense area. CD prevalence was 1·2%. Twenty-one persons were colonized with a toxigenic strain and nine with a non-toxigenic strain. CD-positive persons did not live closer to livestock farms than individuals negative for CD. Antibiotic exposure in the preceding 3 months was a risk factor for CD colonization (odds ratio 3·70; 95% confidence interval 1·25–10·95).

2021 ◽  
Vol 9 ◽  
pp. 205031212110245
Author(s):  
Getu Mosisa ◽  
Bikila Regassa ◽  
Bayise Biru

Introduction: Hypertension remains an emerging public health problem globally, particularly in developing countries. Age, income level, obesity, alcohol consumption, smoking, vegetables and fruit consumption, physical activity and chat chewing were some risk factors of hypertension. However, there are limited data on the epidemiology of hypertension in Ethiopia. This study aimed to assess Epidemiology of Hypertension among the community of selected towns of Wollega zones. Methods: A community-based cross-sectional study was conducted from 1 to 30 June 2019 in selected towns of Wollega zones. A multistage sampling technique was used to select 840 study participants. Data were collected using the WHO STEP wise approach. The data were coded and entered into EpiData 3, and exported to SPSS version 20.0 for analysis. Bivariate and multivariable logistic regression analyses were conducted. Statistical significance was declared at p-value < 0.05. Results: The study included a total of 838 respondents with a response rate of 99.7%. The prevalence of hypertension was found to be 189 (22.6%) (95% confidence interval = 19.9%–25.2%). Of this, 108 (12.9%) and 81 (9.7%) of female and male were hypertensive, respectively. Age groups of 30–44 years (adjusted odds ratio = 2.65 (1.43, 4.89)), 45–59 years (adjusted odds ratio = 3.55 (1.79, 7.04)), above 60 years (adjusted odds ratio = 2.97 (1.43, 6.18)), having history of alcohol consumption (adjusted odds ratio = 4.29 (2.4, 7.66)), involving in vigorous physical activity (adjusted odds ratio = 0.096 (0.028, 0.33)), not walking to and from the work (adjusted odds ratio = 13.12 (8.34, 20.67)), being overweight (adjusted odds ratio = 1.98 (1.21, 3.25)), inadequate fruits serving per day (adjusted odds ratio = 2.93 (1.75, 4.88)) were significantly associated with hypertension. Conclusion: The prevalence of hypertension was found to be high in the study area. Older age, alcohol consumption, not engaging in vigorous activity, physical inactivity, being overweight and inadequate intake of fruits were found to be risk factors for hypertension. Therefore, health care providers should provide extensive health education and promotion on recommended lifestyle modification to tackle the burden of hypertension.


Medicinus ◽  
2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Andree Kurniawan

<p><em>Clostridium difficile</em> (<em>C. difficile</em>) infection mostly found in immunocompromised patient. Most of the patients with neutropenia had hematologic malignancy and come with multiple risk factors for <em>C. difficile</em> infection. The aim of this study is to know the prevalence and characteristic of <em>C. difficile</em> infections in cancer neutropenia patients. This cross-sectional study was done in secondary referral hospital in suburban Karawaci, Tangerang, Banten, Indonesia from June 2014 until Mei 2015. Adult cancer patients hospitalized with neutrophil count less than 1500 10<sup>6</sup> cell/L were included. All patients were checked for antigen and toxin <em>C. difficile</em> in faeces. From 25 patients were evaluated for <em>C. difficile</em> infection in neutropenia. <em>C. difficile</em> antigen only found in one patient or 4% sample.</p><p><strong>Key words: <em>C. difficile</em>, cancer, neutropenia</strong></p>


2020 ◽  
Vol 11 ◽  
pp. 215145932093857
Author(s):  
Dong Min Kim ◽  
Dongjun Park ◽  
Hyojune Kim ◽  
Eui-Sup Lee ◽  
Myung Jin Shin ◽  
...  

Introduction: The aims of this study were to investigate (1) whether demographic factors would be risk factors for severe proximal humerus fracture (PHF), (2) relationship of radiological parameters with bone mineral density (BMD), deltoid tuberosity index (DTI), or severe PHF, and (3) correlation between DTI and BMD. Methods: We conducted a cross-sectional study based on radiographs and medical records taken during admission or the visit to the orthopedic clinic. We reviewed consecutive 100 adult patients who were diagnosed with PHF in our hospital from March 2014 to December 2016. Three- and 4-part fractures were regarded as severe PHFs. Univariable and multivariable logistic regression analyses were performed to evaluate risk factors for severe PHF. Also, we investigated the correlation between BMD and DTI using the additional BMD data of the patients who underwent shoulder surgeries. Results: This study included 62 nonsevere PHFs and 38 severe PHFs. There were 30 male and 70 female patients with a mean age of 66.4 ± 16.4 years. Mean T score of BMD was −2.5 ± 0.9 at the time of injury. Logistic regression analyses showed that age (odds ratio: 1.044, range: 1.011-1.079, P = .009) and sex (odds ratio of females: 3.763, range: 1.236-11.459, P = .020) were related to severe PHF. The group satisfying the radiological parameter criteria had significantly higher rates of severe PHF. The correlation coefficient (r) between DTI and T score was 0.555 ( P < .001). Discussion and Conclusion: Older age and female were the independent risk factors for severe PHF. Conversely, BMD and other medical comorbidities were not risk factors for severe PHF. Deltoid tuberosity index showed significantly high intraclass correlation coefficient and a strong correlation with the T score of BMD. Therefore, DTI may be useful for screening osteoporosis in PHF patients. Level of Evidence: Level IV, Cross-sectional study.


2011 ◽  
Vol 140 (10) ◽  
pp. 1800-1808 ◽  
Author(s):  
B. BISDORFF ◽  
J. L. SCHOLHÖLTER ◽  
K. CLAUßEN ◽  
M. PULZ ◽  
D. NOWAK ◽  
...  

SUMMARYPrevalence of and risk factors associated with MRSA-ST398 carriage in 1872 (response 70%) farmers and neighbouring residents in a pig- and poultry-dense area in Germany were investigated using a cross-sectional study and self-sampling nasal swabs. In the population, 1% without occupational livestock contact and 24% with occupational livestock contact tested positive for MRSA-ST398. The group without occupational livestock contact was 3·8 times [95% confidence interval (CI) 1·5–9·3] more likely to be colonized if a household member had livestock contact and 3·2 times (95% CI 1·4–7·4) more likely if they regularly made private farm visits (e.g. to buy eggs or milk). In the group with occupational livestock contact, pig contact had an odds ratio of 7·1 (95% CI 2·9–17·2) for MRSA-ST398 acquisition. This is the first study to associate private farm visits with acquisition of MRSA; more research to explore the exact transmission routes is necessary.


2020 ◽  
pp. 9-17
Author(s):  
Ibrahima K. Ibrahima BARRY ◽  
Ibrahima CONDE ◽  
Emmanuel CAMARA ◽  
Marie E. HYJAZI ◽  
Moustapha KOUYATE

Introduction. Overweight is a consequence of nutritional transitions, seden-tarity lifestyle, and poverty. Objective. To determine the prevalence of overweight in schools. Population and methods. This was a descriptive cross-sectional study, uni and bi varied analytics, and logistic regression. The CHI2 of Pearson, and Wald have been ap-plied. Odds ratio (OR), and risk factors were estimated. Results. Data concerned 300 children (49% of boys), with a sex ratio of 1.02, an average age of 14 (±2 years), and an overweight of 25%. Factors associated with overweight were ethnicity type [P - 0.000 (OR to 95%) 1.00 (0.000 – 2.000)], gender [P - 0.006 (OR to 95% CI) 2.00 (1.000 – 3.000)], family history: obesity [P - 0.000 (OR to 95% CI) 3.00 (1.000 – 6.000)], high blood pressure (HBP) [P - 0.015 (OR to 95% CI) 1.00 (1.000 – 3.000)],type 2 diabetes (T2D) [P - 0.002 (OR to 95% CI) 2.00 (1.000 – 4.000)], meals number [P - 0.000 (OR to 95% CI) 3.00 (2.000 – 6.000)], activities by week [P - 0.000 (OR to 95% CI) 4.00 (2.000 – 7.000)], and age [P - 0.000 (OR to 95% CI) 7.00 (4.068 –12.000)]. Conclusion. Overweight is high in boys. Family history, as obesity, T2D, HBP, meals number, lacks of activities increase this risk.


2020 ◽  
Vol 19 (2) ◽  
Author(s):  
Hui Jie Wong ◽  
Sakinah Harith ◽  
Pei Lin Lua ◽  
Khairul Azmi Ibrahim

INTRODUCTION: Control of modifiable risk factors is important in recurrent stroke prevention strategies. This study aimed to determine the control of blood pressure and other cardiovascular risk profiles among poststroke patients. Factors associated with uncontrolled blood pressure were also determined. MATERIAL AND METHODS: A cross-sectional study was conducted in the outpatient clinics of three hospitals located in the East Coast region of Peninsular Malaysia from May to August 2019. Information on socio-demographic characteristics, clinical profiles, and lifestyle practices were acquired. Univariate and multivariate logistic regression analyses were carried out. Crude odds ratio and adjusted odds ratio (aOR) were reported. RESULTS: From a total of 398 stroke patients, majority of the respondents were elderly with first-ever stroke, ischaemic type, and duration of stroke less than 24 months. Uncontrolled blood pressure (52%), overweight and obesity (65%), abdominal obesity (54%), and low physical activity level (65%) were common among the patients. Patients with hypertension (aOR= 3.11, 95% CI: 1.38, 6.99), diabetes mellitus (aOR 1.57, 95% CI: 1.03, 2.38), not taking prescribed medication every day (aOR 2.28, 95% CI: 1.29, 4.01), overweight (aOR 1.75, 95% CI:1.02, 2.99), obesity (aOR 1.99, 95% CI: 1.12, 3.53), and low physical activity level (aOR 2.10, 95% CI: 1.35, 3.27) were at a higher risk of having uncontrolled blood pressure. CONCLUSION: Uncontrolled blood pressure and other major cardiovascular risk factors were highly prevalent among poststroke patients. Increased efforts must be made to optimise the risk profiles management of these high-risk patients to prevent recurrent vascular events in the future. 


Author(s):  
Chaitanya R. Patil ◽  
Durgesh Prasad Sahoo ◽  
Manjusha Dhoble ◽  
Abhijit Kherde ◽  
Asim Inamdar

Background: Hypertension is a silent killer and global public health problem. With the advent of globalization affecting the lifestyle of the population, non-communicable diseases like hypertension, diabetes etc. is affecting the young adults (18 to 40 years). The aim of the study was to estimate the prevalence of hypertension and its associated risk factors among young adults (18 to 40 years) attending a tertiary care centre of Nagpur.Methods: This was a cross sectional study on 370 participants of age 18 to 40 years attending the outpatient department of urban health training centre in Nagpur. Data was collected using pretested and pre designed questionnaire and anthropometric measurements were done by standard guidelines. Blood pressure was measured using sphygmomanometer in sitting position. Data was analyzed using Epi info version 7.2. Chi square test/ fisher’s exact test has been used to find the difference between two proportions. Unadjusted odds ratio was calculated for various risk factors studied. Stepwise logistic regression analysis was done to calculate the adjusted odds ratio. Results: The prevalence of hypertension was found to be 23.24%. The prevalence was higher among males (25%) when compared to females (22.3%). Body mass index and waist hip ratio were significantly higher among the hypertensive when compared to normotensive study population (p<0.01). For every one year increase in age, the odds ratio increases by 1.06 (1.02 to 1.09) and the subjects who were overweight were having 2.15 odds of being hypertensive. Conclusions: We found a high prevalence of hypertension among the adults of age group of 18 to 40 years. The population with high body mass index, high waist to hip ratio and age group of 30 to 40 years were found to be associated with hypertension. Early surveillance and prompt treatment forms will help in decreasing the cardiovascular risk of young adults in near future. 


1999 ◽  
Vol 35 (3) ◽  
pp. 188-192 ◽  
Author(s):  
JM Scarlett ◽  
J Saidla ◽  
J Hess

A cross-sectional study evaluating potential risk factors for odontoclastic resorptive lesions (ORL) in feline teeth was conducted. Owners of 32 cats with ORL and 27 cats without ORL were interviewed regarding their respective cat's demographic characteristics, diet, and medical and dental histories. Four factors were identified as significantly associated with ORL using unconditional logistic regression. A history of dental disease (gingivitis, calculus, or periodontal disease; odds ratio [OR], 4.5); city residence (OR, 4.4); and being an exclusively indoor cat (OR, 4.5) were associated with an increased risk for ORL. Consumption of commercial treats (OR, 0.3) appeared protective for ORL.


2021 ◽  
Vol 9 ◽  
pp. 205031212110097
Author(s):  
Manamo Hayamo ◽  
Tsegaye Alemayehu ◽  
Bereket Tadesse ◽  
Enkosilassie Mitiku ◽  
Zufan Bedawi

Objective: This study was aimed at identifying Shigella and Salmonella infection, their antibiotic susceptibility pattern and associated risk factors among children with diarrhea who attended Alamura Health Center. Method: A facility-based cross-sectional study was conducted on 263 children aged below 14 years with diarrhea. A structured questionnaire was used to collect socio-demographic and clinical data after obtaining the necessary consent from their parents or caretakers. The culture and sensitivity tests were performed using the standard operating procedure of the microbiology laboratory. Results: Accordingly, 20/263 (7.6%), 95% confidence interval: 4.4%–11.4% Shigella and 1/263 (0.38%), 95% confidence interval: 0.0%–1.1% Salmonella were isolated. Shigella dysenteriae was dominant 11 (4.2%), followed by Shigella spp. 9 (3.42%) and Salmonella typ 1 (0.38%). The isolates showed 71.4% overall resistance to ampicillin and 61.9% for augmentin and tetracycline, whereas 95.2% of the isolates were sensitive to ciprofloxacin, 85.9% to ceftriaxone and ceftazidime, 81% to gentamycin, 76.2% to chloramphenicol, 66.7% to cefuroxime and 52.4% to cotrimoxazole. The habit of washing hands after toilet use for a while (adjusted odds ratio: 235.1, 95% confidence interval: 20.9–2643.3, p < 0.000) and storing cooked food in an open container for later use (adjusted odds ratio: 36.44, 95% confidence interval: 5.82–228.06, p < 0.000) showed a statistically significant association. Conclusion: High level of Shigella and single Salmonella was isolated. Ampicillin, augmentin and tetracycline were resistant and ciprofloxacin, ceftriaxone, ceftazidime, gentamycin, chloramphenicol, cefuroxime and cotrimoxazole were relatively sensitive. Hand-washing after defecation for some time and storing of foods for later use in an open container were statistically associated. Therefore, to alleviate this infection, the concerned body should focus on imparting health education for hand-wash after defecation and storing food in a closed container for later use is mandatory.


2019 ◽  
Vol 47 (02) ◽  
pp. 132-132
Author(s):  
Sebastian Ganz

Nathues C, Janssen E, Duengelhoef A et al. Cross-sectional study on risk factors for Porcine Reproductive and Respiratory Syndrome virus sow herd instability in German breeding herds. Acta Vet Scand 2018; 60 (1): 1–8 In mit PRRSV (Porcine Reproductive and Respiratory Syndrom Virus) infizierten Schweinebeständen zeigen die Tiere oftmals ernsthafte klinische Symptome. Die Schwere der Symptomatik hängt von der Virulenz der jeweiligen Virusstämme ab. Deshalb ist die Impfung gegen diesen Erreger sinnvoll und wird empfohlen, auch wenn sie nicht immer klinische Fälle verhindert bzw. das Virus vollends eliminiert. Aufgrund dessen rückt die Prävention durch Verbesserung der innerbetrieblichen Abläufe zunehmend in den Fokus. Um solche Maßnahmen erfolgreich etablieren zu können, ist es wichtig, den epidemiologischen Status der Herde und mögliche Risikofaktoren zu kennen. Ziel der Studie war deshalb, die Prävalenz der Infektion in Sauenbetrieben in Norddeutschland zu eruieren und verschiedene Arbeitsabläufe hinsichtlich des Risikos der Erregerverbreitung zu untersuchen.


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