Risk Factors for Severe Proximal Humerus Fracture and Correlation Between Deltoid Tuberosity Index and Bone Mineral Density

Introduction: The aims of this study were to investigate (1) whether demographic factors would be risk factors for severe proximal humerus fracture (PHF), (2) relationship of radiological parameters with bone mineral density (BMD), deltoid tuberosity index (DTI), or severe PHF, and (3) correlation between DTI and BMD. Methods: We conducted a cross-sectional study based on radiographs and medical records taken during admission or the visit to the orthopedic clinic. We reviewed consecutive 100 adult patients who were diagnosed with PHF in our hospital from March 2014 to December 2016. Three- and 4-part fractures were regarded as severe PHFs. Univariable and multivariable logistic regression analyses were performed to evaluate risk factors for severe PHF. Also, we investigated the correlation between BMD and DTI using the additional BMD data of the patients who underwent shoulder surgeries. Results: This study included 62 nonsevere PHFs and 38 severe PHFs. There were 30 male and 70 female patients with a mean age of 66.4 ± 16.4 years. Mean T score of BMD was −2.5 ± 0.9 at the time of injury. Logistic regression analyses showed that age (odds ratio: 1.044, range: 1.011-1.079, P = .009) and sex (odds ratio of females: 3.763, range: 1.236-11.459, P = .020) were related to severe PHF. The group satisfying the radiological parameter criteria had significantly higher rates of severe PHF. The correlation coefficient (r) between DTI and T score was 0.555 ( P < .001). Discussion and Conclusion: Older age and female were the independent risk factors for severe PHF. Conversely, BMD and other medical comorbidities were not risk factors for severe PHF. Deltoid tuberosity index showed significantly high intraclass correlation coefficient and a strong correlation with the T score of BMD. Therefore, DTI may be useful for screening osteoporosis in PHF patients. Level of Evidence: Level IV, Cross-sectional study.

Download Full-text

Epidemiology of hypertension in selected towns of Wollega zones, Western Ethiopia, 2019: A community-based cross-sectional study

SAGE Open Medicine ◽

10.1177/20503121211024519 ◽

2021 ◽

Vol 9 ◽

pp. 205031212110245

Author(s):

Getu Mosisa ◽

Bikila Regassa ◽

Bayise Biru

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Alcohol Consumption ◽

Odds Ratio ◽

Adjusted Odds Ratio ◽

Cross Sectional Study ◽

Care Providers ◽

Sectional Study ◽

Community Based ◽

Cross Sectional

Introduction: Hypertension remains an emerging public health problem globally, particularly in developing countries. Age, income level, obesity, alcohol consumption, smoking, vegetables and fruit consumption, physical activity and chat chewing were some risk factors of hypertension. However, there are limited data on the epidemiology of hypertension in Ethiopia. This study aimed to assess Epidemiology of Hypertension among the community of selected towns of Wollega zones. Methods: A community-based cross-sectional study was conducted from 1 to 30 June 2019 in selected towns of Wollega zones. A multistage sampling technique was used to select 840 study participants. Data were collected using the WHO STEP wise approach. The data were coded and entered into EpiData 3, and exported to SPSS version 20.0 for analysis. Bivariate and multivariable logistic regression analyses were conducted. Statistical significance was declared at p-value < 0.05. Results: The study included a total of 838 respondents with a response rate of 99.7%. The prevalence of hypertension was found to be 189 (22.6%) (95% confidence interval = 19.9%–25.2%). Of this, 108 (12.9%) and 81 (9.7%) of female and male were hypertensive, respectively. Age groups of 30–44 years (adjusted odds ratio = 2.65 (1.43, 4.89)), 45–59 years (adjusted odds ratio = 3.55 (1.79, 7.04)), above 60 years (adjusted odds ratio = 2.97 (1.43, 6.18)), having history of alcohol consumption (adjusted odds ratio = 4.29 (2.4, 7.66)), involving in vigorous physical activity (adjusted odds ratio = 0.096 (0.028, 0.33)), not walking to and from the work (adjusted odds ratio = 13.12 (8.34, 20.67)), being overweight (adjusted odds ratio = 1.98 (1.21, 3.25)), inadequate fruits serving per day (adjusted odds ratio = 2.93 (1.75, 4.88)) were significantly associated with hypertension. Conclusion: The prevalence of hypertension was found to be high in the study area. Older age, alcohol consumption, not engaging in vigorous activity, physical inactivity, being overweight and inadequate intake of fruits were found to be risk factors for hypertension. Therefore, health care providers should provide extensive health education and promotion on recommended lifestyle modification to tackle the burden of hypertension.

Download Full-text

Analysis of the relationship between periodontitis and osteoporosis/fractures: a cross-sectional study

BMC Oral Health ◽

10.1186/s12903-021-01496-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Seok-Jin Hong ◽

Byoung-Eun Yang ◽

Dae-Myoung Yoo ◽

Sung-Jae Kim ◽

Hyo-Geun Choi ◽

...

Keyword(s):

Odds Ratio ◽

Bone Destruction ◽

Epidemiological Data ◽

Income Group ◽

Cross Sectional Study ◽

Inflammatory Factors ◽

Sectional Study ◽

Mineral Density ◽

Cross Sectional ◽

History Of

Abstract Background Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone destruction that may lead to osteoporosis development. The association between periodontitis and osteoporosis has been documented; however, the findings remain unclear. This study aimed to identify the association between periodontitis and osteoporosis using a cross-sectional study design and Korean Genome and Epidemiology Study (KoGES) health examinee data. Methods This cross-sectional study used epidemiological data from the KoGES during 2004–2016. Of 125,324 participants (age, 40–79 years), 9969 with periodontitis and 115,332 controls (without periodontitis) were selected. We analyzed the history of osteoporosis and fractures of all participants. All participants were examined according to age, sex, income group, obesity, smoking habits, alcohol consumption, and food intake. To analyze the odds ratio (OR) of periodontitis for those with osteoporosis and fractures, a logistic regression model was used. Results The adjusted odds ratio (aOR) of periodontitis for osteoporosis was 2.16 (95% confidence interval [CI], 2.01–2.31; P < 0.001). The aOR of periodontitis for any fracture was 1.54 (95% CI 1.46–1.62; P < 0.001). Conclusion Osteoporosis and fractures are associated with periodontitis. Performing regular oral hygiene and examinations of bone mineral density are recommended to prevent aggravation of osteoporosis and periodontitis.

Download Full-text

Clinical Features of And Risk Factors for Normoalbuminuric Diabetic Kidney Disease In Hospitalized Patients With Type 2 Diabetes Mellitus: A Retrospective Cross-Sectional Study

10.21203/rs.3.rs-194700/v1 ◽

2021 ◽

Author(s):

Qi Dai ◽

Nan Chen ◽

Ling Zeng ◽

Xin-Jie Lin ◽

Feng-Xiu Jiang ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Diabetic Kidney Disease ◽

Cross Sectional Study ◽

Regression Analyses ◽

Sectional Study ◽

Cross Sectional

Abstract Background: Normoalbuminuric diabetic kidney disease (NADKD) is a newly defined DKD, the clinical features and pathogenesis for which are still being understood. This study aimed to investigate the features and risk factors for NADKD in patients with type 2 diabetes mellitus (T2DM).Methods: A retrospective cross-sectional study was conducted. The related clinical and laboratory data of patients with T2DM hospitalized between August 2012 and January 2020 were collected for statistical analysis. We classified the patients with T2DM into four groups on the basis of the presence or absence of albuminuria and reduced estimated glomerular filtration rate (eGFR). Analysis of variance, the Kruskal–Wallis test, and the chi-square test were used to compare the groups. Binary logistic regression analyses with a forward stepwise method were performed to explore the risk factors for renal dysfunction in hospitalized patients with normoalbuminuric T2DM.Results: Among the 1620 patients evaluated, 500 (30.9%) had DKD, of which 9% had NADKD. The prevalence of stroke, cardiovascular events, carotid plaque, and peripheral arterial disease in NADKD was significantly higher than in a non-DKD control group (normoalbuminuric T2DM patients with eGFR of ≥60 ml/min/1.73 m2). Regression analyses revealed that three significant independent factors were associated with NADKD: age (OR = 1.089, confidence interval [CI] 95% [1.055−1.123], p < 0.001), previous use of renin−angiotensin system inhibitors (RASIs; OR = 2.330, CI 95% [1.212−4.481], p = 0.011), and glycated hemoglobin (HbA1c; OR = 0.839, CI 95% [0.716−0.983], p = 0.03). Conclusions: NADKD is mainly associated with macrovascular rather than microvascular complications. NADKD is more common in patients with normoalbuminuric T2DM with older age, previous use of RASIs, and good glycemic control.

Download Full-text

Association between the number of prosthetic crowns and periodontitis: a cross-sectional study

10.21203/rs.3.rs-183824/v1 ◽

2021 ◽

Author(s):

Yun-Jeong Kim ◽

Jae-Young Lee ◽

Young Ku ◽

Hyun-Jae Cho

Keyword(s):

Odds Ratio ◽

Cross Sectional Study ◽

Demographic Variables ◽

Nutrition Examination Survey ◽

Regression Analyses ◽

Sectional Study ◽

Multivariate Logistic Regression ◽

Cross Sectional ◽

Health And Nutrition ◽

Health Related

Abstract BackgroundAlthough the presence of prosthetic restorations has been associated with plaque accumulation, gingivitis, and periodontitis, there is a lack of large epidemiological investigations providing credible evidence on the association of prosthetic crowns with periodontitis. The purpose of the study was to analyze the association between the number of prosthetic crowns and the presence of periodontitis.MethodsThis study was based on the Seventh Korea National Health and Nutrition Examination Survey (2016-2018). A total of 12,689 participants over the age of 19 years were surveyed. Multivariate logistic regression analyses were used to identify the association between the number of prosthetic crowns and periodontitis after adjusting for potential confounders, including demographic variables, socio-economic characteristics, oral health-related variables, and oral and systemic clinical variables. ResultsThe odds ratio of periodontitis showed statistically significant differences in the anterior and posterior regions, and the prevalence of periodontal disease increased as the number of crown prostheses increased. Participants with 6–10 and 11 prosthetic crowns had 1.24 and 1.28 times higher prevalence of periodontitis, respectively, than patients with no prosthetic crown.ConclusionsThe results of this study show that the number of prosthetic crowns present in adults is related to the prevalence of periodontitis.

Download Full-text

Risk factors for diminished bone mineral density among male hemodialysis patients—a cross-sectional study

Archives of Osteoporosis ◽

10.1007/s11657-012-0110-3 ◽

2012 ◽

Vol 7 (1-2) ◽

pp. 283-290 ◽

Cited By ~ 4

Author(s):

Sasan Mirfakhraee ◽

Khashayar Sakhaee ◽

Joseph Zerwekh ◽

Beverley Adams-Huet ◽

Ugis Gruntmanis

Keyword(s):

Risk Factors ◽

Bone Mineral Density ◽

Bone Mineral ◽

Cross Sectional Study ◽

Hemodialysis Patients ◽

Sectional Study ◽

Mineral Density ◽

Cross Sectional

Download Full-text

Clinical features of and risk factors for normoalbuminuric diabetic kidney disease in hospitalized patients with type 2 diabetes mellitus: a retrospective cross-sectional study

BMC Endocrine Disorders ◽

10.1186/s12902-021-00769-8 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Qi Dai ◽

Nan Chen ◽

Ling Zeng ◽

Xin-Jie Lin ◽

Feng-Xiu Jiang ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Diabetic Kidney Disease ◽

Cross Sectional Study ◽

Regression Analyses ◽

Sectional Study ◽

Cross Sectional

Abstract Background Normoalbuminuric diabetic kidney disease (NADKD) is a newly defined DKD, the clinical features and pathogenesis for which are still being understood. This study aimed to investigate the features and risk factors for NADKD in patients with type 2 diabetes mellitus (T2DM). Methods A retrospective cross-sectional study was conducted. The related clinical and laboratory data of patients with T2DM hospitalized between August 2012 and January 2020 were collected for statistical analysis. We classified the patients with T2DM into four groups on the basis of the presence or absence of albuminuria and reduced estimated glomerular filtration rate (eGFR). Analysis of variance, the Kruskal–Wallis test, and the chi-square test were used to compare the groups. Binary logistic regression analyses with a forward stepwise method were performed to explore the risk factors for renal dysfunction in hospitalized patients with normoalbuminuric T2DM. Results Among the 1620 patients evaluated, 500 (30.9%) had DKD, of which 9% had NADKD. The prevalence of stroke, cardiovascular events, carotid plaque, and peripheral arterial disease in NADKD was significantly higher than in a non-DKD control group (normoalbuminuric T2DM patients with eGFR of ≥60 ml/min/1.73 m2). Regression analyses revealed that three significant independent factors were associated with NADKD: age (OR = 1.089, confidence interval [CI] 95% [1.055–1.123], p < 0.001), previous use of renin−angiotensin system inhibitors (RASIs; OR = 2.330, CI 95% [1.212–4.481], p = 0.011), and glycated hemoglobin (HbA1c; OR = 0.839, CI 95% [0.716–0.983], p = 0.03). Conclusions NADKD is mainly associated with macrovascular rather than microvascular complications. NADKD is more common in patients with normoalbuminuric T2DM with older age, previous use of RASIs, and good glycemic control.

Download Full-text

ASYMMETRY OF BONE MINERAL DENSITY OF THE HIPS IN PATIENTS WITH UNILATERAL KNEE OSTEOARTHRITIS: A CROSS-SECTIONAL STUDY

Journal of Musculoskeletal Research ◽

10.1142/s0218957711500059 ◽

2011 ◽

Vol 14 (01) ◽

pp. 1150005 ◽

Cited By ~ 1

Author(s):

Alireza Ashraf ◽

Seyed Mostafa Jazayeri Shooshtari ◽

Kaynoosh Homayouni ◽

Sharareh Roshanzamir ◽

Mohsen Zafarghasempoor ◽

...

Keyword(s):

Bone Mineral Density ◽

Knee Osteoarthritis ◽

Bone Mineral ◽

Lumbar Vertebrae ◽

Cross Sectional Study ◽

Z Score ◽

Sectional Study ◽

Mineral Density ◽

Cross Sectional ◽

T Score

Background: Osteoarthritis of any joint may exert different effects on bone mineral density that may be the result of several mechanisms including change in the pattern of weight load distribution. In this cross-sectional study we tried to find correlations between unilateral knee osteoarthritis and bone mineral density of hips and lumbar vertebrae. Methods: Forty three patients with knee osteoarthritis (unilateral or more severe in one side) were recruited in this study. The American college of Rheumatology Criteria was followed for the diagnosis of osteoarthritis. Dual X-Ray absorptiometry was used to obtain the T score and the Z score of the hips and lumbar vertebrae. Results: The T score and Z score of the hip and T score of the femoral neck, at the side with ipsilateral knee osteoarthritis was lower than the other side (p < 0.05). The mean Z score and T score of the vertebrae was negative irrespective of the side of osteoarthritis. Conclusions: Bone mineral density of the hip with ipsilateral knee osteoarthritis was lower than the other side, which suggests that BMD may be sensitive to some extent in detecting osteoporosis in these patients; it has also been observed that osteoarthritis might not affect bone mineral density of the hips and lumbar vertebrae in the same manner or to the same extent.

Download Full-text

Factors Associated With Low Bone Mineral Density in Adults With Type 1 Diabetes: A Cross-Sectional Study

Journal of the Endocrine Society ◽

10.1210/jendso/bvab048.559 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

pp. A275-A276

Author(s):

Julie-Catherine Coll ◽

Élodie Garceau ◽

Laëtitia Michou ◽

S John Weisnagel ◽

Fabrice Mac-Way ◽

...

Keyword(s):

Univariate Analysis ◽

Cross Sectional Study ◽

Z Score ◽

Sectional Study ◽

Mineral Density ◽

Cross Sectional ◽

Factors Associated ◽

T Score ◽

The Past

Abstract Context: Individuals with type 1 diabetes (T1D) have a two- to threefold increase in fracture risk at any site, and up to a sevenfold increase in hip fracture risk compared to those without diabetes. The mechanisms accounting for this bone fragility are not yet fully understood. Objectives: 1) To determine factors associated with low bone mineral density (BMD) in patients with T1D; 2) To assess the association between skin advanced glycation end products (AGEs) and low BMD in patients with T1D. Methods: These are preliminary data from patients with T1D included in a cross-sectional study aiming at comparing the prevalence of vertebral fractures between adult patients with T1D from two tertiary care centers and age- and sex-matched controls without diabetes. Patients were eligible if they were aged ≥20 years and had a diagnosis of T1D for at least 5 years. Patients were classified as having a low BMD if Z-score was ≤-2.0 at any site (lumbar spine, femoral neck, total hip, radius) in patients aged <50 years or if T-score was ≤-1.0 at any site in patients aged ≥50 years or in postmenopausal women. Skin AGEs (surrogate marker of overall including bone AGEs) were measured by skin autofluorescence (AGE Reader ®). Unpaired t-tests or Chi-squared tests were used to compare characteristics between patients with or without a low BMD. Variables associated with a low BMD were determined by univariate analysis and were subsequently included in a multivariate logistic regression analysis if p<0.1 in the univariate analysis. All variables were tested for multicollinearity. Results: 106 patients with T1D were included (mean age 45.2±15.0 years; mean BMI 26.3±5.1 kg/m2; 54.7% women; mean duration of diabetes 28.2±13.6 years; 44.3% with a microvascular complication). Mean HbA1C over the past 3 years was 7.5±0.8%. A third of the patients (31.1%) had a low BMD (3 patients using Z-score; 30 patients using T-score). Patients with a low BMD were older (58.3 vs 39.3 years, p<0.001), had a lower mean HbA1C over the past 3 years (7.3% vs 7.6%, p=0.047), a longer diabetes duration (36.1 vs 24.6 years, p<0.001), higher skin AGEs (2.50 vs 2.03, p<0.001), a higher prevalence of microvascular complications (63.6% vs 37.7%, p=0.02) and a higher prevalence of abnormal albumin to creatinine ratio (ACR ≥2.0) on the day of assessment (38.7% vs 11.8%, p=0.003). In multivariate regression analysis, age (p<0.001), abnormal ACR (p=0.003) and lower mean HbA1C over the past 3 years (p=0.02) remained significantly associated with a low BMD. Skin AGEs were correlated with age (r=0.56) and diabetes duration (r=0.47). Conclusion: In this population with T1D, a low BMD was independently associated with older age, abnormal ACR and, unexpectedly, with a lower mean HbA1C over the past 3 years, but not with skin AGEs.

Download Full-text

Association of multimorbidity with higher levels of urinary incontinence: a cross-sectional study of 23 089 individuals aged ≥15 years residing in Spain

British Journal of General Practice ◽

10.3399/bjgp20x713921 ◽

2020 ◽

Vol 71 (702) ◽

pp. e71-e77

Author(s):

Louis Jacob ◽

Guillermo Felipe López-Sánchez ◽

Hans Oh ◽

Jae Il Shin ◽

Igor Grabovac ◽

...

Keyword(s):

Urinary Incontinence ◽

Marital Status ◽

Odds Ratio ◽

Chronic Conditions ◽

Cross Sectional Study ◽

National Health Survey ◽

Regression Analyses ◽

Sectional Study ◽

Cross Sectional ◽

High Prevalence

BackgroundOne can assume a relatively high prevalence of urinary incontinence (UI) in people with multimorbidity. However, literature in this area is scarce. There is a need for further robust research to aid GPs to identify patients at a particular risk for UI, and to initiate the early treatment and multidisciplinary management of this condition.AimTo examine the association between multimorbidity and UI in 23 089 individuals aged ≥15 years and residing in Spain.Design and settingThis study used data from the Spanish National Health Survey 2017, a cross-sectional sample of 23 089 participants aged ≥15 years residing in Spain (54.1% female; mean [standard deviation] age = 53.4 [18.9] years).MethodUI and 30 other physical and mental chronic conditions were self-reported. Multimorbidity was defined as the presence of ≥2 physical and/or mental chronic conditions (excluding UI). Control variables included sex, age, marital status, education, smoking, and alcohol consumption. Multivariable logistic regression analyses were conducted to assess the association between multimorbidity and UI.ResultsThe prevalence of UI was 5.9% in this sample. UI was more frequent in the presence than in the absence of each one of the 30 chronic conditions (P<0.001). The proportion of people with UI was also higher in the multimorbidity than in the no-multimorbidity group (9.8% versus 0.7%, P<0.001). After adjusting for several potential confounders (that is, sex, age, marital status, education, smoking, and alcohol), there was a significant and positive relationship between multimorbidity and UI (odds ratio = 5.02, 95% confidence interval [CI] = 3.89 to 6.59, P<0.001).ConclusionIn this large sample of Spanish individuals aged ≥15 years, suffering from multimorbidity was associated with a significantly higher level of UI.

Download Full-text

Prevalence of overweight and obesity in urban schools in Kamsar Republic of Guinea

Nutrition & Santé ◽

10.30952/9.1.2 ◽

2020 ◽

pp. 9-17

Author(s):

Ibrahima K. Ibrahima BARRY ◽

Ibrahima CONDE ◽

Emmanuel CAMARA ◽

Marie E. HYJAZI ◽

Moustapha KOUYATE

Keyword(s):

Risk Factors ◽

Family History ◽

Odds Ratio ◽

Cross Sectional Study ◽

Overweight And Obesity ◽

Sectional Study ◽

Cross Sectional ◽

Factors Associated ◽

Republic Of Guinea

Introduction. Overweight is a consequence of nutritional transitions, seden-tarity lifestyle, and poverty. Objective. To determine the prevalence of overweight in schools. Population and methods. This was a descriptive cross-sectional study, uni and bi varied analytics, and logistic regression. The CHI2 of Pearson, and Wald have been ap-plied. Odds ratio (OR), and risk factors were estimated. Results. Data concerned 300 children (49% of boys), with a sex ratio of 1.02, an average age of 14 (±2 years), and an overweight of 25%. Factors associated with overweight were ethnicity type [P - 0.000 (OR to 95%) 1.00 (0.000 – 2.000)], gender [P - 0.006 (OR to 95% CI) 2.00 (1.000 – 3.000)], family history: obesity [P - 0.000 (OR to 95% CI) 3.00 (1.000 – 6.000)], high blood pressure (HBP) [P - 0.015 (OR to 95% CI) 1.00 (1.000 – 3.000)],type 2 diabetes (T2D) [P - 0.002 (OR to 95% CI) 2.00 (1.000 – 4.000)], meals number [P - 0.000 (OR to 95% CI) 3.00 (2.000 – 6.000)], activities by week [P - 0.000 (OR to 95% CI) 4.00 (2.000 – 7.000)], and age [P - 0.000 (OR to 95% CI) 7.00 (4.068 –12.000)]. Conclusion. Overweight is high in boys. Family history, as obesity, T2D, HBP, meals number, lacks of activities increase this risk.

Download Full-text