Multimodal Emotion Integration in Bipolar Disorder: An Investigation of Involuntary Cross-Modal Influences between Facial and Prosodic Channels

2014 ◽  
Vol 20 (5) ◽  
pp. 525-533 ◽  
Author(s):  
Tamsyn E. Van Rheenen ◽  
Susan L. Rossell

AbstractThe ability to integrate information from different sensory channels is a vital process that serves to facilitate perceptual decoding in times of unimodal ambiguity. Despite its relevance to psychosocial functioning, multimodal integration of emotional information across facial and prosodic modes has not been addressed in bipolar disorder (BD). In light of this paucity of research we investigated multimodal processing in a BD cohort using a focused attention paradigm. Fifty BD patients and 52 healthy controls completed a task assessing the cross-modal influence of emotional prosody on facial emotion recognition across congruent and incongruent facial and prosodic conditions, where attention was directed to the facial channel. There were no differences in multi-modal integration between groups at the level of accuracy, but differences were evident at the level of response time; emotional prosody biased facial recognition latencies in the control group only, where a fourfold increase in response times was evident between congruent and incongruent conditions relative to patients. The results of this study indicate that the automatic process of integrating multimodal information from facial and prosodic sensory channels is delayed in BD. Given that interpersonal communication usually occurs in real time, these results have implications for social functioning in the disorder. (JINS, 2014, 20, 1–9)

2006 ◽  
Vol 189 (3) ◽  
pp. 254-259 ◽  
Author(s):  
Carla Torrent ◽  
Anabel Martínez-Arán ◽  
Claire Daban ◽  
Jose Sánchez-Moreno ◽  
Mercè Comes ◽  
...  

BackgroundPersistent impairments in neurocognitive function have been described in bipolar disorder.AimsTo compare the cognitive performance of patients with bipolar II disorder with that of patients with bipolar I disorder and a healthy control group.MethodThe study included 71 euthymic patients with bipolar disorder (38 bipolar I, 33 bipolar II), who were compared on clinical and neuropsychological variables (e.g. executive function, attention, verbal and visual memory) and contrasted with 35 healthy controls on cognitive performance.ResultsCompared with controls, both bipolar groups showed significant deficits in most cognitive tasks including working memory (Digit Span Backwards, P=0.002) and attention (Digit Span Forwards, P=0.005; Trail Making Test, P=0.001). Those with type II disorders had an intermediate level of performance between the bipolar I group and the control group in verbal memory (P < 0.005) and executive functions (Stroop interference task, P=0.020).ConclusionsCognitive impairment exists in both subtypes of bipolar disorder, although more so in the bipolar I group. The best predictors of poor psychosocial functioning in bipolar II disorder were subclinical depressive symptoms, early onset of illness and poor performance on a measure related to executive function.


Medicina ◽  
2021 ◽  
Vol 57 (1) ◽  
pp. 54
Author(s):  
Mario Luciano ◽  
Luca Steardo ◽  
Gaia Sampogna ◽  
Vito Caivano ◽  
Carmen Ciampi ◽  
...  

Background and objectives: Bipolar disorder (BD) is one of the most burdensome psychiatric illnesses, being associated with a negative long-term outcome and the highest suicide rate. Although affective temperaments can impact on BD long-term outcome, their role remains poorly investigated. The aims of the present study are to describe the clinical characteristics of patients with BD more frequently associated with the different affective temperaments and to assess the relation between affective temperaments and severity of clinical picture in a sample of patients with BD. Materials and Methods: A total of 199 patients have been recruited in the outpatients units of two university sites. Patients’ psychiatric symptoms, affective temperaments, and quality of life were investigated through validated assessment instruments. Results: Predominant cyclothymic and irritable temperaments are associated to higher number of relapses, poorer quality of life, higher rates of aggressive behaviors, and suicide attempts. Conversely, the predominant hyperthymic disposition was a protective factor for several outcome measures, including relapse rate, severity of anxiety, depressive and manic symptoms, suicidality, and earlier age at onset. One limitationo of the present study is that the recruitment took place in two university sites; therefore, our findings cannot be fully generalized to the whole community of BD patients. Other limitations are the lack of a control group and the cross-sectional design of the study. Conclusions: The early identification of affective temperaments can help clinicians to identify those BD patients who are more likely to show a poor long-term outcome. An early screening of affective temperaments can be useful to develop targeted integrated pharmacological and psychosocial interventions.


2021 ◽  
Vol 54 (2) ◽  
pp. 70-77
Author(s):  
William Mellick ◽  
James J. Prisciandaro ◽  
Helena Brenner ◽  
Delisa Brown ◽  
Bryan K. Tolliver

<b><i>Introduction:</i></b> Shared neurobehavioral characteristics of bipolar disorder (BD) and alcohol dependence (AD), including heightened sensitivity to reward (SR), may account for high rates of BD and AD co-occurrence (BD + AD). However, empirical research is lacking. The present multimethod investigation examined SR and sensitivity to punishment (SP) among these patient groups using a reliable and well-validated self-report questionnaire of SR and SP along with a laboratory task specifically designed to distinguish SR and SP activation. <b><i>Methods:</i></b> One-hundred participants formed 4 groups: BD + AD (<i>n</i> = 40), BD (<i>n</i> = 18), AD (<i>n</i> = 25), and healthy controls (<i>n</i> = 17). Clinical interviews were administered, and participants completed the Sensitivity to Punishment and Sensitivity to Reward Questionnaire (SPSR-Q) and the Point Score Reaction Test behavioral task. Pearson correlations, hierarchical linear regression, and 2 × 2 factorial general linear modeling with Bonferroni-corrected pairwise comparisons were performed. <b><i>Results:</i></b> BD and AD main effects were significant on self-reported SR and SP; however, BD × AD interactions were not. BD + AD individuals were significantly higher on self-reported SR than BD and AD individuals, yet all clinical groups were similar on SP. Behavioral response times did not distinguish groups nor did they associate with self-report data. <b><i>Discussion/Conclusion:</i></b> BD and AD had additive, rather than interactive, effects on self-reported SR and SP. The methods employed, paired with their application to the present sample, may account for a lack of positive findings with behavioral data.


2020 ◽  
pp. 174702182098552
Author(s):  
Lucette Toussaint ◽  
Aurore Meugnot ◽  
Christel Bidet-Ildei

The present experiment aimed to gain more information on the effect of limb nonuse on the cognitive level of actions and, more specifically, on the content of the motor program used for grasping an object. For that purpose, we used a hand-grasping laterality task that is known to contain concrete information on manipulation activity. Two groups participated in the experiment: an immobilized group, including participants whose right hand and arm were fixed with a rigid splint and an immobilization vest for 24 hours, and a control group, including participants who did not undergo the immobilization procedure. The main results confirmed a slowdown of sensorimotor processes, which is highlighted in the literature, with slower response times when the participants identified the laterality of hand images that corresponded to the immobilized hand. Importantly, the grip-precision effect, highlighted by slower response times for hands grasping a small sphere versus a large sphere, is impaired by 24 hours of limb nonuse. Overall, this study provided additional evidence of the disengagement of sensorimotor processes due to a short period of limb immobilization.


Author(s):  
BARBARA GELLER ◽  
KRISTINE BOLHOFNER ◽  
JAMES L. CRANEY ◽  
MARLENE WILLIAMS ◽  
MELISSA P. DELBELLO ◽  
...  

2003 ◽  
Vol 15 (8) ◽  
pp. 1135-1148 ◽  
Author(s):  
Annett Schirmer ◽  
Sonja A. Kotz

The present study investigated the interaction of emotional prosody and word valence during emotional comprehension in men and women. In a prosody-word interference task, participants listened to positive, neutral, and negative words that were spoken with a happy, neutral, and angry prosody. Participants were asked to rate word valence while ignoring emotional prosody, or vice versa. Congruent stimuli were responded faster and more accurately as compared to incongruent emotional stimuli. This behavioral effect was more salient for the word valence task than for the prosodic task and was comparable between men and women. The event-related potentials (ERPs) revealed a smaller N400 amplitude for congruent as compared to emotionally incongruent stimuli. This ERP effect, however, was significant only for the word valence judgment and only for female listeners. The present data suggest that the word valence judgment was more difficult and more easily influenced by task-irrelevant emotional information than the prosodic task in both men and women. Furthermore, although emotional prosody and word valence may have a similar influence on an emotional judgment in both sexes, ERPs indicate sex differences in the underlying processing. Women, but not men, show an interaction between prosody and word valence during a semantic processing stage.


1994 ◽  
Vol 165 (S24) ◽  
pp. 45-51 ◽  
Author(s):  
Zhanhuai Fan ◽  
Jingkang Huang ◽  
Qihui Wu ◽  
Shaxi Jiang

A priority for psychiatric rehabilitation workers in China is to develop less-restrictive methods for managing the estimated 2500 chronically institutionalised patients who are symptomatically stable and have adequate psychosocial functioning but have no family members who are able or willing to take them home. We transferred 45 chronic schizophrenic male in-patients to an open-door rehabilitation ward where they were given as much freedom as possible and encouraged to take part in occupational, social, and recreational activities. The Nurses Observation Scale for Inpatient Evaluation (NOSIE) was used to compare the psychosocial functioning of the 43 patients who completed the year-long trial with that of 43 similar patients who received standard in-patient treatment on a locked ward. Over the year, the experimental group showed a significant improvement in overall functioning, whereas the control group showed no improvement. These findings suggest that open-door rehabilitation wards situated within the hospital can mobilise latent psychosocial functioning and may be a good method for re-introducing chronic schizophrenic patients in China back into the community.


2021 ◽  
Author(s):  
Andrey Rocha Rocca ◽  
José Celio da Rocha Lima Filho ◽  
Rafael Barbosa Roque Pesconi ◽  
Déborah Alvim Monteiro Batista Alves ◽  
João Victor Coutinho Pereira ◽  
...  

Abstract Background: Bipolar disorder (BD) is a severe, recurrent and chronic disorder associated with cognitive impairment, reduction in quality of life and substantially reduction in psychosocial functioning. It presents high rates of comorbidity with cardiovascular and cerebrovascular diseases, diabetes and metabolic syndrome. Individuals with bipolar disorder need to focus their attention and treatment on mental and physical health. Physical exercise is often recommended in bipolar disorder, based on extrapolation from the major depressive disorder literature, theory and clinical expertise. However, studies tend to exclude individuals with BD or make no distinction between diagnostic groups, which leads to heterogeneity and difficulty in generalizing the results. The aim of this review is to evaluate the role of physical exercise as an intervention in bipolar disorder treatment. Method: The study populations must be humans, aged 18 years or older, with a clinical diagnosis of Bipolar Disorder (BD) according to a recognised widely-used diagnostic classification approach, confirmed with a structured interview. We will evaluate two main outcomes (mood symptoms improvement and functioning) and an additional outcome (prevention of relapse/recurrence). The search strategy will be based on the PICOS framework, using medical subject headings, on the following databases: MEDLINE (via Pubmed), EMBASE, CENTRAL, SPORTDiscus (via EBSCO), PsycINFO (via APA) and OpenGrey Repository. Selection and data collection process will be carried out by two authors, independently. Risk of bias and quality of evidence will be graded acording ROB-2 and GRADE. We will present a narrative and quantitative synthesis of the results from the included studies. Regarding quantitative data, we will extract means (M) and standard deviations (SD), when available, to calculate the standardised mean difference (SMD). Effects size will be calculated using SMD and 95% confidence interval and heterogeneity will be assessed. Subgroup analysis will be conducted to explore heterogeneity across studies depending on quality and quantity of the data extracted.Discussion: To date, there wasn't a systematic review with only randomized controlled trials on effects of physical activity on BD. Because of this, we will conduct this systematic review trying to estabilish the effects of exercise on mood, functionality and prevention of relapse.Registration: submitted


Viruses ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1947
Author(s):  
Stefanie E. M. van van Opstal ◽  
Emma J. Dogterom ◽  
Marlies N. Wagener ◽  
Femke K. Aarsen ◽  
Harald S. Miedema ◽  
...  

Advances in antiretroviral treatment improved the life expectancy of perinatally HIV-infected children. However, growing up with HIV provides challenges in daily functioning. This cross-sectional cohort study investigated the neuropsychological and psychosocial functioning of a group of perinatally HIV-infected children in the Netherlands and compared their outcomes with Dutch normative data and outcomes of a control group of uninfected siblings. The children’s functioning was assessed with internationally well-known and standardized questionnaires, using a multi-informant approach, including the perspectives of caregivers, teachers, and school-aged children. In addition, we explored the associations of socio-demographic and medical characteristics of the HIV-infected children with their neuropsychological and psychosocial functioning. Caregivers reported compromised functioning when compared to Dutch normative data for HIV-infected children in the areas of attention, sensory processing, social-emotional functioning, and health-related quality of life. Teachers reported in addition compromised executive functioning for HIV-infected children. A comparison with siblings revealed differences in executive functioning, problems with peers, and general health. The concurrent resemblance between HIV-infected children and siblings regarding problems in other domains implies that social and contextual factors may be of influence. A family-focused approach with special attention to the child’s socio-environmental context and additional attention for siblings is recommended.


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