Normative Data for the CERAD-NP for Healthy High-Agers (80–84 years) and Effects of Age-Typical Visual Impairment and Hearing Loss

Abstract Objectives: This study aims to establish reference data for nondemented adults between 80 and 84 years of age based on the German version of the Consortium to Establish a Registry for Alzheimer’s disease Neuropsychological (CERAD-NP) test battery and to assess the possible influence of hearing and vision impairments on CERAD-NP performance. Methods: Two hundred one volunteers were examined with the German CERAD-NP test battery, and 18 test scores were calculated from the data. The sample included 99 men (49%), the mean age was 81.8 years (SD = 1.3), and the mean years of education were 13.9 (SD = 3.1). Percentiles for continuous and percentile ranks for discrete test scores were calculated separately for four norm groups. The groups were classified according to gender and education. Multiple regression analysis was used to predict cognitive performance from visual acuity and hearing ability. Results: The normative data obtained were consistent with other findings from younger and older age groups. Worse visual acuity predicted slower performance in the Trail Making Test (TMT). None of the other CERAD-NP tests were correlated to sensory functions. Conclusions: Using age-appropriate reference data, such as that established here for the 80–84 year age group can help to improve the detection of cognitive decline and prevent biases that arise when old-old adults are compared to younger old adults. Visual acuity should be considered an influencing factor on TMT performance.

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Determining Filipino Normative Data for a Battery of Neuropsychological Tests: The Filipino Norming Project (FNP)

Dementia and Geriatric Cognitive Disorders Extra ◽

10.1159/000500519 ◽

2019 ◽

Vol 9 (2) ◽

pp. 260-270

Author(s):

Jacqueline Cotoong Dominguez ◽

Thien Kieu Thi Phung ◽

Ma. Fe Payno de Guzman ◽

Krizelle Cleo Fowler ◽

Macario Reandelar Jr ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Neuropsychological Tests ◽

Normative Data ◽

Neuropsychological Test ◽

Test Battery ◽

Cognitive Domains ◽

Neuropsychological Test Battery ◽

The Mean ◽

Effect Of Age

Background: Filipino normative data for neuropsychological tests are lacking. Objectives: This study aimed to determine the Filipino normative data for the Filipino Norming Project (FNP) Neuropsychological Battery, combining the Alzheimer’s Disease Assessment Scale – Cognitive (ADAS-Cog) and the Neuropsychological Test Battery from the Uniform Dataset of Alzheimer’s Disease Center (UDS-ADC). Methods: We recruited participants 60 years and older with normal cognition (MMSE score of 25 and above and did not fulfill criteria for dementia according to DSM-IV criteria). Psychologists administered the tests to the study participants. We conducted multivariate analyses to study the effect of age, gender, and education on test performance. Results: A total of 191 participants underwent the FNP Neuropsychological Test Battery. The mean age was 68.8 years (SD 5.4). The majority were female (84.1%). The mean score of ADAS-Cog was 9.98 (SD 4.74). The effect of education was prominent throughout the cognitive domains tested while the effect of age was limited to a few cognitive domains. The mean ADAS-Cog scores were 11.80 ± 4.40 for primary education, 9.93 ± 5.08 for secondary, and 8.15 ± 3.95 for tertiary. On average, women scored 2.75 points lower than men and performed better on the verbal components. Men performed better on the constructional praxis component. The same effect of education and gender was observed for the UDS-ADC. Conclusion: For the first time, normative data are available for the ADAS-Cog and UDS-ADC for a Filipino older population. This study stresses the importance of establishing population-specific normative data, taking into account the specific sociocultural and linguistic context of that population.

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Variance Components of the WISC-R in Eleven Age Groups

Psychological Reports ◽

10.2466/pr0.1976.38.3.1001 ◽

1976 ◽

Vol 38 (3) ◽

pp. 1001-1002 ◽

Cited By ~ 2

Author(s):

W. David Dinning

Keyword(s):

Variance Components ◽

Normative Data ◽

Age Groups ◽

Psychological Tests ◽

The Mean ◽

Mean Variance

The mean variance components of the WISC-R were calculated from normative data and compared with previously reported mean variance components of the WISC. Only slight differences were noted in the mean variance components of the two tests. Both the WISC and WISC-R subtests appear to possess relatively less specific variance than do several other psychological tests. It does not appear that the patterning of WISC-R subtests will be any less frustrating than patterning on the WISC.

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BACK MUSCLES' ENDURANCE IN ADOLESCENTS AND ADULTS: NORMATIVE DATA FOR A SUB-SAHARAN AFRICAN POPULATION

Journal of Musculoskeletal Research ◽

10.1142/s0218957711500047 ◽

2011 ◽

Vol 14 (01) ◽

pp. 1150004

Author(s):

Chidozie E. Mbada ◽

Olusola Ayanniyi ◽

Rufus A. Adedoyin ◽

Olubusola E. Johnson ◽

Olumide O. Dada

Keyword(s):

Normative Data ◽

Age Groups ◽

African Population ◽

Teaching Hospitals ◽

Normative Values ◽

Back Muscles ◽

Cross Sectional ◽

Endurance Time ◽

The Mean ◽

Sub Saharan

Purpose: Back muscles' endurance assessment provides an objective indicator of the functional capacity of the back. This study sought to establish a gender and age referenced normative data for back muscles endurance for a Sub-Saharan African population. Methods: This cross sectional study involved 1253 (623 male, 630 female) consecutive participants between the ages of 11 and 69 years without a history of symptomatic LBP within one year to the time of the study. Participants were recruited from eight secondary schools, two universities and two teaching hospitals, respectively. All participants underwent assessment of the back extensor muscles' endurance using the modified Biering-Sorensen test of muscular endurance. The mean and percentile data for endurance time were determined for six gender/age groups classified on a range of 10 years. Results: The mean endurance time (ET) of all the participants was 119 ± 53.6 secs. Men exhibited a significantly (p = 0.001) higher ET than women (125.9 ± 53.3 versus 112.6 ± 53.1 secs). Using percentile values cut-points; poor endurance (less than 25th), moderate endurance (25–75th) and good endurance (> 75th percentile) were < 85.0 secs, 85–163 secs, and > 163 secs, respectively for male; and < 69.8 secs, 69.8–148 secs and > 148 secs, respectively for female. Conclusion: The normative values derived in this study would be useful in assessing impairment in back muscles' endurance in both healthy and patient populations. The results suggest that age, gender and anthropometric factors can significantly influence back muscles' endurance.

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Incidence of Tooth Loss in Adults: A 4-Year Population-Based Prospective Cohort Study

International Journal of Dentistry ◽

10.1155/2017/6074703 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 6

Author(s):

Manoelito Ferreira Silva-Junior ◽

Marília Jesus Batista ◽

Maria da Luz Rosário de Sousa

Keyword(s):

Older Adults ◽

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Tooth Loss ◽

Age Groups ◽

Population Based ◽

Missing Teeth ◽

Old Adults ◽

The Mean

Objective. To verify the incidence of tooth loss in extended age group of adults in 4 years. Materials and Methods. The prospective cohort study assessed adults (20–64 years old) between 2011 and 2015, from Piracicaba, São Paulo, Brazil. The dependent variable was cumulative incidence of tooth loss, assessed by difference between missing teeth (M) of decayed, missing, and filled tooth index (DMFT) in 2011 and 2015. Participants were stratified into young (20–44 years old) and older (45–64 years old) adults. Mann–Whitney U test (p<0.05) was used to compare the means of incidence of tooth loss between age groups. Results. After four years, 57.7% (n=143) of adults were followed up and the mean incidence of tooth loss was 0.91 (SD = 1.65); among these, 51 adults (35.7%) who lost their teeth showed mean tooth loss of 2.55 (SD = 1.86). In older adults, incidence of tooth loss was higher (p=0.008), but no difference between age groups was found when only adults with incidence of tooth loss were assessed (p=0.844). Conclusion. There was higher incidence of tooth loss in older adults after four years, however, without difference between age groups when only those who lost teeth were evaluated.

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Normative data for pituitary size and volume in the general population between 50 and 66 years

Pituitary ◽

10.1007/s11102-021-01150-7 ◽

2021 ◽

Author(s):

Erik Magnus Berntsen ◽

Matias Daleng Haukedal ◽

Asta Kristine Håberg

Keyword(s):

General Population ◽

Anterior Pituitary ◽

Normative Data ◽

Brain Mri ◽

Age Groups ◽

Surrogate Marker ◽

Future Research ◽

3D Mri ◽

The Mean ◽

Size Estimates

Abstract Purpose The main aim of this study was to provide normative data for pituitary height and volume in persons between 50 and 66 years in the general population. The secondary aim was to establish a convenient surrogate marker of pituitary size for use in routine radiological practice. Methods From a geographically defined prospective healthy study, 1006 participants between 50 and 66 years had a brain MRI, of which 988 (519 women) were included in this study. We measured the mid-sagittal height, max-sagittal height and total volume of the anterior pituitary lobe based on T1-weighted 3D MRI images. Results Both the mean mid-sagittal and max-sagittal pituitary height were significantly larger in women compared to men, with 4.9 ± 1.7 mm versus 4.4 ± 1.4 mm (p < .001) for the mean mid-sagittal height and 6.8 ± 1.2 mm versus 6.1 ± 1.1 mm (p < 0.001) for the mean max-sagittal height. The mean anterior pituitary lobe volume was also significantly larger in women than in men (494 ± 138 mm3 vs. 405 ± 118 mm3) (p < 0.001). There were no significant differences in these pituitary sagittal heights nor volume in either sex between the age groups 50–54, 55–59 and 60–66 years. The 95th percentile for mid-sagittal height, max-sagittal height and pituitary volume was 7.7 mm, 8.6 mm and 851 mm3 for women and 6.6 mm, 7.8 mm and 610 mm3 for men. Conclusion This study show that women have a larger pituitary gland than men in the age group between 50 and 66 years and provides normative data for pituitary size estimates which can be used for clinical diagnostic purposes as well as future research.

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Short-term Comparison of Refractive Errors between Two Different Age Groups after LASEK for Moderate Myopia

Journal of the Korean Ophthalmological Society ◽

10.3341/jkos.2021.62.11.1478 ◽

2021 ◽

Vol 62 (11) ◽

pp. 1478-1482

Author(s):

Mi Jeong Kim ◽

Ji Seon An ◽

Ja Yoon Moon ◽

Hee Young Kim ◽

Jin Seok Choi ◽

...

Keyword(s):

Visual Acuity ◽

Age Groups ◽

Refractive Errors ◽

Age Group ◽

Short Term ◽

Corrected Visual Acuity ◽

Group I ◽

The Mean ◽

Group Ii

Purpose: To investigate the safety of laser epithelial keratomileusis (LASEK) by drawing a comparison between two groups divided according to age (18-19 vs. 20-21 years old).Methods: The study was conducted as a retrospective analysis including 339 patients (678 eyes) who underwent LASEK between January 2017 and April 2020. Patients were divided by age group, group I (18-19 years old) and group II (20-21 years old). The objectives of the study included determination of visual acuity and refractive errors before and at 1, 3, and 6 months after the procedure.Results: The preoperative mean spherical equivalents (SEs) were -4.73 ± 0.88 diopters (D) in group I and -4.58 ± 0.87 D in group II (p = 0.34). At 1 month postoperatively, mean SEs were 0.32 ± 0.46 D in group I and 0.26 ± 0.59 D in group II (p = 0.18). At 3 months postoperatively, the mean SEs were 0.30 ± 0.47 D in group I and 0.28 ± 0.50 D in group II (p = 0.67). At 6 months postoperatively, the mean SEs were 0.15 ± 0.47 D in group I and 0.14 ± 0.50 D in group II (p = 0.89). There were no significant differences in postoperative best corrected visual acuity between group I and group II at 1, 3, or 6 months (p = 0.20, p = 0.13, and p = 0.11, respectively).Conclusions: There were no significant differences in postoperative mean SE or safety of LASEK between moderate myopia patients 18-19 years old and those 20-21 years old.

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Reference Data and Known-Groups Validity of the EQ-5D-5L for Vietnam

10.21203/rs.3.rs-229794/v1 ◽

2021 ◽

Author(s):

Mai Quynh Vu ◽

Giang Bao Kim ◽

Minh Van Hoang ◽

Lars Lindholm ◽

Sun Sun ◽

...

Keyword(s):

General Population ◽

Reference Data ◽

Age Groups ◽

Five Dimensions ◽

Population Norms ◽

Gender And Age ◽

Vietnamese Population ◽

The Mean ◽

Eq Vas

Abstract PurposeThis study aims to provide EQ-5D-5L reference data of the general Vietnamese population and to test the EQ-5D-5L’ known-groups validity among people living with hypertension in Vietnam.MethodsThe EQ-5D-5L population norms were obtained via a representative sample from a general population of 1200 adults. Outcomes of the population norms were presented through five dimensions and five levels, EQ-VAS, and EQ-5D-5L indexes. Descriptive statistics of these outcomes were categorised by gender and age groups. Evidence of the known-groups validity was based on a sample of 577 non-hypertensive adults, 242 individuals with undiagnosed and 477 individuals with diagnosed hypertension. A hypothesis was formulated that people with worse health status would have lower EQ-VAS and EQ-5D-5L indexes. ResultsFor the EQ-5D-5L population norms, 54.4% of the respondents reported having full health. The mean EQ-VAS and EQ-5D-5L indexes were 81.10 and 0.94, respectively. The EQ-VAS and EQ-5D-5L indexes were higher among males, people at younger ages, those with more education, a paid job, and single. The mean EQ-VAS and EQ-5D-5L indexes of people in the diagnosed hypertension group were statistically significantly lower than they were in the other two groups. ConclusionThe EQ-5D-5L population norms were derived for the Vietnamese general population. The EQ-5D-5L can distinguish the quality-of-life differences among Vietnamese with hypertension.

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Establishment of a normative data for cervical and lumbar spine movements using spinal column analysis system

Indian Journal of Aerospace Medicine ◽

10.25259/ijasm_9_2020 ◽

2020 ◽

Vol 64 ◽

pp. 51-55

Author(s):

NK Tripathy ◽

MG Praveen ◽

V Raghunandan ◽

M Mukherjee ◽

M Dahiya

Keyword(s):

Lumbar Spine ◽

Normative Data ◽

Age Groups ◽

Spinal Column ◽

Normative Values ◽

German Population ◽

Male Population ◽

Normal Ranges ◽

The Mean ◽

Analysis System

Introduction: The current assessment of spine movements during aeromedical evaluation of aircrew is performed using the CMS 20 spinal column analysis system. However, in the present configuration, the normal ranges of cervical and lumbar spine motions depicted by the equipment are based on normative data of German population measured by goniometric method. The study was conducted to generate normative values of cervical and lumbar spine movements with respect to age-specific Indian male population. Material and Methods: The study included a total of 225 healthy male Indian volunteers, divided into three age groups; <25 years, 25–35 years, and above 35 years, with 75 subjects in each age group. In each participant, ten cervical spine movements and six lumbar spine movements were recorded using CMS 20 S spinal column analysis system. The data were statistically analyzed to establish normative data for each of the cervical and lumbar spine movements for three age groups (<25 years, 25–35 years, and >35 years). Results: The mean age, height & weight of the participants were 21.2, 28.3 and 39.4 years, 173.1, 171.6 and 170.6 cm, 65.9, 68.7 and 70.2 kg respectively for the three different age groups - <25 years, 25-35 years and >35 years. The mean values along with standard deviation of the ten cervical and eight lumbar spine movements were derived and presented for the three different age groups. Conclusion: The normative data generated in the present study as per the three age groups may be used as reference values for male Indian personnel for that specific age groups for the assessment of cervical and lumbar spine movements using spinal column analysis system. The data may also be used as baseline data for aeromedical evaluation and future aviation research involving the same equipment.

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Age related volume of cadaver-prostates in Bangladesh

Ibrahim Medical College Journal ◽

10.3329/imcj.v4i2.6501 ◽

1970 ◽

Vol 4 (2) ◽

pp. 74-77

Author(s):

Rukshana Ahmed ◽

Shamim Ara

Keyword(s):

Prostate Gland ◽

Age Groups ◽

Clinical Settings ◽

Cross Sectional ◽

Medical College ◽

Age Related ◽

Group A ◽

Key Words Prostate ◽

The Mean ◽

Group B

Pathological changes in the prostate gland occur commonly with advancing age including inflammation, atrophy, hyperplasia and carcinoma and a change in volume is also evident. Estimation of volume of prostate may be useful in a variety of clinical settings. A cross-sectional descriptive study was designed to see the changes in volume of the prostate with advancing age and done in the Department of Anatomy, Dhaka Medical College, Dhaka from August 2006 to June 2007. The study was performed on 70 post-mortem human prostates collected from the unclaimed dead bodies that were under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age groups; group A (10-20 years), group B (21-40 years) and group C (41-70 years). Volume of the sample was measured by using the ellipsoid formula. The mean ± SD volume of prostate was 7.68 ± 3.64 cm3 in group A, 10.61 ± 3.99 cm3 in group B and 15.40 ± 6.31 cm3 in group C. Mean difference in volume between group A and group C, group B and group C were statistically significant (p<0.001). Statistically significant positive correlation was found between age and volume of prostate (r = + 0.579, p < 0.001). Key Words: Prostate; volume; Bangladeshi. DOI: 10.3329/imcj.v4i2.6501Ibrahim Med. Coll. J. 2010; 4(2): 74-77

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Observation of the Pulp Chamber of Maxillary First Premolars: A Micro-computed Tomographic Study

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405615666191016125937 ◽

2020 ◽

Vol 16 (3) ◽

pp. 224-230

Author(s):

Gozde Serindere ◽

Ceren Aktuna Belgin ◽

Kaan Orhan

Keyword(s):

Root Canal ◽

Age Groups ◽

Slice Thickness ◽

Micro Ct ◽

Micro Computed Tomography ◽

Pulp Chamber ◽

Anatomical Structures ◽

Computed Tomographic ◽

The Mean ◽

Chamber Floor

Background: There are a few studies about the evaluation of maxillary first premolars internal structure with micro-computed tomography (micro-CT). The aim of this study was to assess morphological features of the pulp chamber in maxillary first premolar teeth using micro- CT. Methods: Extracted 15 maxillary first premolar teeth were selected from the patients who were in different age groups. The distance between the pulp orifices, the diameter of the pulp and the width of the pulp chamber floor were measured on the micro-CT images with the slice thickness of 13.6 µm. The number of root canal orifices and the presence of isthmus were evaluated. Results: The mean diameter of orifices was 0.73 mm on the buccal side while it was 0.61 mm on palatinal side. The mean distance between pulp orifices was 2.84 mm. The mean angle between pulp orifices was -21.53°. The mean height of pulp orifices on the buccal side was 4.32 mm while the mean height of pulp orifices on the palatinal side was 3.56 mm. The most observed shape of root canal orifices was flattened ribbon. No isthmus was found in specimens. Conclusion: Minor anatomical structures can be evaluated in more detail with micro-CT. The observation of the pulp cavity was analyzed using micro-CT.

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